Katharina Rox

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 25

Top Topics

Candida Albicans

Respiratory Syncytial Virus

Crystal Structure

Top Venues

Nature communications

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Antibiotics (Basel, Switzerland)

This page only lists publications with an associated author ORCID identifier.

Publications

Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Daniel Kohnhäuser, Tim Seedorf, Katarina Cirnski, Dominik Heimann, Janetta Coetzee, Sylvie Sordello, Jana Richter, Moritz Stappert, Jean-Francois Sabuco, David Corbett, Eric Bacqué, Katharina Rox, Jennifer Herrmann, Aurelie Vassort, Daniel Krug, Andreas Kirschning, Mark Brönstrup
Optimization of the Central α-Amino Acid in Cystobactamids to the Broad-Spectrum, Resistance-Breaking Antibiotic CN-CC-861. Journal of medicinal chemistry (2024)
Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Katharina Rox, Annett Kühne, Jennifer Herrmann, Rolf Jansen, Stephan Hüttel, Steffen Bernecker, Yohannes Hagos, Mark Brönstrup, Marc Stadler, Thomas Hesterkamp, Daniel Krug
Interaction of the Atypical Tetracyclines Chelocardin and Amidochelocardin with Renal Drug Transporters. ACS pharmacology & translational science 7 (7) (2024)
Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Katharina Rox, Annett Kühne, Jennifer Herrmann, Rolf Jansen, Stephan Hüttel, Steffen Bernecker, Yohannes Hagos, Mark Brönstrup, Marc Stadler, Thomas Hesterkamp, Daniel Krug
Interaction of the Atypical Tetracyclines Chelocardin and Amidochelocardin with Renal Drug Transporters. ACS pharmacology & translational science 7 (7) (2024)
Daan Willocx, Lorenzo Bizzarri, Alaa Alhayek, Deepika Kannan, Patricia Bravo, Boris Illarionov, Katharina Rox, Jonas Lohse, Markus Fischer, Andreas Martin Kany, Hannes Hahne, Matthias Rottmann, Matthias Witschel, Audrey Odom John, Mostafa M Hamed, Eleonora Diamanti, Anna Katharina Herta Hirsch
Targeting Plasmodium falciparum IspD in the Methyl-d-erythritol Phosphate Pathway: Urea-Based Compounds with Nanomolar Potency on Target and Low-Micromolar Whole-Cell Activity. Journal of medicinal chemistry (2024)
Sebastian Mielniczuk, Katharina Hoff, Fady Baselious, Yunqi Li, Jörg Haupenthal, Andreas M Kany, Maria Riedner, Holger Rohde, Katharina Rox, Anna Katharina Herta Hirsch, Isabelle Krimm, Wolfgang Sippl, Ralph Holl
Development of Fragment-Based Inhibitors of the Bacterial Deacetylase LpxC with Low Nanomolar Activity. Journal of medicinal chemistry (2024)
Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Mostafa M Hamed, Ahmed S Abdelsamie, Katharina Rox, Christian Schütz, Andreas Martin Kany, Teresa Röhrig, Stefan Schmelz, Wulf Blankenfeldt, Alejandro Arce Rodriguez, José Manuel Borrero-de Acuña, Dieter Jahn, Jessica Rademacher, Felix C C Ringshausen, Nina Cramer, Burkhard Tümmler, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Martin Empting
Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (5) (2023)
Kashaf Khalid, Katharina Rox
All Roads Lead to Rome: Enhancing the Probability of Target Attainment with Different Pharmacokinetic/Pharmacodynamic Modelling Approaches. Antibiotics (Basel, Switzerland) 12 (4) (2023)
Katharina Rox, Rolf Jansen, Tadeja Lukežič, Marina Greweling-Pils, Jennifer Herrmann, Marcus Miethke, Stephan Hüttel, Fabienne Hennessen, Antoine Abou Fayad, Cornelia Holzhausen, Carina Vingsbo Lundberg, Joanne Teague, Enge Sudarman, Lisa Bülter, Thomas Hesterkamp, Marc Stadler, Mark Brönstrup, Daniel Krug
Pharmacokinetic and pharmacodynamic evaluation of the atypical tetracyclines chelocardin and amidochelocardin in murine infection models. Microbiology spectrum (2023)
Mostafa M Hamed, Ahmed S Abdelsamie, Katharina Rox, Christian Schütz, Andreas Martin Kany, Teresa Röhrig, Stefan Schmelz, Wulf Blankenfeldt, Alejandro Arce Rodriguez, José Manuel Borrero-de Acuña, Dieter Jahn, Jessica Rademacher, Felix C C Ringshausen, Nina Cramer, Burkhard Tümmler, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Martin Empting
Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (5) (2023)
Kashaf Khalid, Katharina Rox
All Roads Lead to Rome: Enhancing the Probability of Target Attainment with Different Pharmacokinetic/Pharmacodynamic Modelling Approaches. Antibiotics (Basel, Switzerland) 12 (4) (2023)
Simon Graspeuntner, Katharina Koethke, Celeste Scholz, Lea Semmler, Mariia Lupatsii, Laura Kirchhoff, Jennifer Herrmann, Katharina Rox, Kathrin Wittstein, Nadja Käding, Lars C Hanker, Marc Stadler, Mark Brönstrup, Daniel Krug, Kensuke Shima, Jan Rupp
Sorangicin A Is Active against Chlamydia in Cell Culture, Explanted Fallopian Tubes, and Topical In Vivo Treatment. Antibiotics (Basel, Switzerland) 12 (5) (2023)
Mostafa M Hamed, Ahmed S Abdelsamie, Katharina Rox, Christian Schütz, Andreas Martin Kany, Teresa Röhrig, Stefan Schmelz, Wulf Blankenfeldt, Alejandro Arce Rodriguez, José Manuel Borrero-de Acuña, Dieter Jahn, Jessica Rademacher, Felix C C Ringshausen, Nina Cramer, Burkhard Tümmler, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Martin Empting
Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2023)
Mostafa M Hamed, Ahmed S Abdelsamie, Katharina Rox, Christian Schütz, Andreas Martin Kany, Teresa Röhrig, Stefan Schmelz, Wulf Blankenfeldt, Alejandro Arce Rodriguez, José Manuel Borrero-de Acuña, Dieter Jahn, Jessica Rademacher, Felix C C Ringshausen, Nina Cramer, Burkhard Tümmler, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Martin Empting
Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (5) (2023)
Katharina Rox, Tim Becker, Andrea Schiefer, Miriam Grosse, Alexandra Ehrens, Rolf Jansen, Tilman Aden, Stefan Kehraus, Gabriele M König, Anna K Krome, Marc P Hübner, Karl G Wagner, Marc Stadler, Kenneth M Pfarr, Achim Hoerauf
Pharmacokinetics and Pharmacodynamics (PK/PD) of Corallopyronin A against Methicillin-Resistant Staphylococcus aureus . Pharmaceutics 15 (1) (2022)
Katharina Rox, Tim Becker, Andrea Schiefer, Miriam Grosse, Alexandra Ehrens, Rolf Jansen, Tilman Aden, Stefan Kehraus, Gabriele M König, Anna K Krome, Marc P Hübner, Karl G Wagner, Marc Stadler, Kenneth M Pfarr, Achim Hoerauf
Pharmacokinetics and Pharmacodynamics (PK/PD) of Corallopyronin A against Methicillin-Resistant Staphylococcus aureus . Pharmaceutics 15 (1) (2022)
Katharina Rox, Tim Becker, Andrea Schiefer, Miriam Grosse, Alexandra Ehrens, Rolf Jansen, Tilman Aden, Stefan Kehraus, Gabriele M König, Anna K Krome, Marc P Hübner, Karl G Wagner, Marc Stadler, Kenneth M Pfarr, Achim Hoerauf
Pharmacokinetics and Pharmacodynamics (PK/PD) of Corallopyronin A against Methicillin-Resistant Staphylococcus aureus . Pharmaceutics 15 (1) (2022)
Katharina Rox, Tim Becker, Andrea Schiefer, Miriam Grosse, Alexandra Ehrens, Rolf Jansen, Tilman Aden, Stefan Kehraus, Gabriele M König, Anna K Krome, Marc P Hübner, Karl G Wagner, Marc Stadler, Kenneth M Pfarr, Achim Hoerauf
Pharmacokinetics and Pharmacodynamics (PK/PD) of Corallopyronin A against Methicillin-Resistant Staphylococcus aureus . Pharmaceutics 15 (1) (2022)
Christian Schütz, Duy-Khiet Ho, Mostafa Mohamed Hamed, Ahmed Saad Abdelsamie, Teresa Röhrig, Christian Herr, Andreas Martin Kany, Katharina Rox, Stefan Schmelz, Lorenz Siebenbürger, Marius Wirth, Carsten Börger, Samir Yahiaoui, Robert Bals, Andrea Scrima, Wulf Blankenfeldt, Justus Constantin Horstmann, Rebekka Christmann, Xabier Murgia, Marcus Koch, Aylin Berwanger, Brigitta Loretz, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Claus-Michael Lehr, Martin Empting
A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 8 (12) (2021)
Linlin Zhang, Daizong Lin, Xinyuanyuan Sun, Ute Curth, Christian Drosten, Lucie Sauerhering, Stephan Becker, Katharina Rox, Rolf Hilgenfeld
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors. Science (New York, N.Y.) 368 (6489) (2020)