Martin Horn

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 14

Top Topics

Molecular Docking

High Resolution

Fluorescent Probe

Top Venues

ACS infectious diseases

International journal of molecular sciences

Journal of medicinal chemistry

Parasites & vectors

This page only lists publications with an associated author ORCID identifier.

Publications

Zuzana Matoušková, Katarína Orsághová, Pavel Srb, Jana Pytelková, Zdeněk Kukačka, Michal Buša, Ondřej Hajdušek, Radek Šíma, Milan Fábry, Petr Novák, Martin Horn, Petr Kopáček, Michael Mareš
An Unusual Two-Domain Thyropin from Tick Saliva: NMR Solution Structure and Highly Selective Inhibition of Cysteine Cathepsins Modulated by Glycosaminoglycans. International journal of molecular sciences 25 (4) (2024)
Petra Spiwoková, Martin Horn, Jindřich Fanfrlík, Adéla Jílková, Pavla Fajtová, Adrian Leontovyč, Radka Houštecká, Lucia Bieliková, Jiří Brynda, Marta Chanová, Helena Mertlíková-Kaiserová, Eduardo J E Caro-Diaz, Jehad Almaliti, Nelly El-Sakkary, William H Gerwick, Conor R Caffrey, Michael Mareš
Nature-Inspired Gallinamides Are Potent Antischistosomal Agents: Inhibition of the Cathepsin B1 Protease Target and Binding Mode Analysis. ACS infectious diseases 10 (6) (2024)
Petra Spiwoková, Martin Horn, Jindřich Fanfrlík, Adéla Jílková, Pavla Fajtová, Adrian Leontovyč, Radka Houštecká, Lucia Bieliková, Jiří Brynda, Marta Chanová, Helena Mertlíková-Kaiserová, Eduardo J E Caro-Diaz, Jehad Almaliti, Nelly El-Sakkary, William H Gerwick, Conor R Caffrey, Michael Mareš
Nature-Inspired Gallinamides Are Potent Antischistosomal Agents: Inhibition of the Cathepsin B1 Protease Target and Binding Mode Analysis. ACS infectious diseases (2024)
Petra Spiwoková, Martin Horn, Jindřich Fanfrlík, Adéla Jílková, Pavla Fajtová, Adrian Leontovyč, Radka Houštecká, Lucia Bieliková, Jiří Brynda, Marta Chanová, Helena Mertlíková-Kaiserová, Eduardo J E Caro-Diaz, Jehad Almaliti, Nelly El-Sakkary, William H Gerwick, Conor R Caffrey, Michael Mareš
Nature-Inspired Gallinamides Are Potent Antischistosomal Agents: Inhibition of the Cathepsin B1 Protease Target and Binding Mode Analysis. ACS infectious diseases 10 (6) (2024)
Petra Spiwoková, Martin Horn, Jindřich Fanfrlík, Adéla Jílková, Pavla Fajtová, Adrian Leontovyč, Radka Houštecká, Lucia Bieliková, Jiří Brynda, Marta Chanová, Helena Mertlíková-Kaiserová, Eduardo J E Caro-Diaz, Jehad Almaliti, Nelly El-Sakkary, William H Gerwick, Conor R Caffrey, Michael Mareš
Nature-Inspired Gallinamides Are Potent Antischistosomal Agents: Inhibition of the Cathepsin B1 Protease Target and Binding Mode Analysis. ACS infectious diseases 10 (6) (2024)
Zuzana Matoušková, Katarína Orsághová, Pavel Srb, Jana Pytelková, Zdeněk Kukačka, Michal Buša, Ondřej Hajdušek, Radek Šíma, Milan Fábry, Petr Novák, Martin Horn, Petr Kopáček, Michael Mareš
An Unusual Two-Domain Thyropin from Tick Saliva: NMR Solution Structure and Highly Selective Inhibition of Cysteine Cathepsins Modulated by Glycosaminoglycans. International journal of molecular sciences 25 (4) (2024)
Zuzana Matoušková, Katarína Orsághová, Pavel Srb, Jana Pytelková, Zdeněk Kukačka, Michal Buša, Ondřej Hajdušek, Radek Šíma, Milan Fábry, Petr Novák, Martin Horn, Petr Kopáček, Michael Mareš
An Unusual Two-Domain Thyropin from Tick Saliva: NMR Solution Structure and Highly Selective Inhibition of Cysteine Cathepsins Modulated by Glycosaminoglycans. International journal of molecular sciences 25 (4) (2024)
Carina Lemke, Adéla Jílková, Dominic Ferber, Annett Braune, Anja On, Patrick Johe, Alena Zíková, Tanja Schirmeister, Michael Mareš, Martin Horn, Michael Gütschow
Two Tags in One Probe: Combining Fluorescence- and Biotin-based Detection of the Trypanosomal Cysteine Protease Rhodesain. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (62) (2022)
Lenka Ulrychová, Pavel Ostašov, Marta Chanová, Michael Mareš, Martin Horn, Jan Dvořák
Spatial expression pattern of serine proteases in the blood fluke Schistosoma mansoni determined by fluorescence RNA in situ hybridization. Parasites & vectors 14 (1) (2021)
Carina Lemke, Jakub Benýšek, Dominik Brajtenbach, Christian Breuer, Adéla Jílková, Martin Horn, Michal Buša, Lenka Ulrychová, Annika Illies, Katharina F Kubatzky, Ulrike Bartz, Michael Mareš, Michael Gütschow
An Activity-Based Probe for Cathepsin K Imaging with Excellent Potency and Selectivity. Journal of medicinal chemistry 64 (18) (2021)
Adéla Jílková, Petra Rubešová, Jindřich Fanfrlík, Pavla Fajtová, Pavlína Řezáčová, Jiří Brynda, Martin Lepsik, Helena Mertlíková-Kaiserová, Cory D Emal, Adam R Renslo, William R Roush, Martin Horn, Conor R Caffrey, Michael Mareš
Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors. ACS infectious diseases 7 (5) (2020)
Michael Mareš, Martin Horn, Jindřich Fanfrlík, Jim Küppers, Petr Pachl, Pavlína Řezáčová, Martin Lepsik, Pavla Fajtová, Petra Rubešová, Marta Chanová, Conor R Caffrey, Michael Gütschow, Michael Mareš
Azanitrile Inhibitors of the SmCB1 Protease Target Are Lethal to Schistosoma mansoni: Structural and Mechanistic Insights into Chemotype Reactivity. ACS infectious diseases 7 (1) (2020)
Radka Houštecká, Martin Hadzima, Jindřich Fanfrlík, Jiří Brynda, Lenka Pallová, Iva Hánová, Helena Mertlíková-Kaiserová, Martin Lepšík, Martin Horn, Martin Smrčina, Pavel Majer, Michael Mareš
Biomimetic Macrocyclic Inhibitors of Human Cathepsin D: Structure-Activity Relationship and Binding Mode Analysis. Journal of medicinal chemistry 63 (4) (2020)
Adrian Leontovyč, Lenka Ulrychová, Anthony J O'Donoghue, Jiří Vondrášek, Lucie Marešová, Martin Hubálek, Pavla Fajtová, Marta Chanová, Zhenze Jiang, Charles S Craik, Conor R Caffrey, Michael Mareš, Jan Dvořák, Martin Horn
SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties. PLoS neglected tropical diseases 12 (4) (2018)