William R Roush (William Roush)

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 12

Top Topics

Multiple Myeloma

Tyrosine Kinase

Trypanosoma Cruzi

Top Venues

Journal of medicinal chemistry

Cancer research

Organic letters

This page only lists publications with an associated author ORCID identifier.

Publications

Karen L Burger, Mario R Fernandez, Mark B Meads, Praneeth Reddy Sudalagunta, Paula S Oliveira, Rafael Renatino Canevarolo, Raghunandan Reddy Alugubelli, Alexandre Tungsevik, Gabe De Avila, Maria Silva, Allison I Graeter, Hongyue Dai, Nicole D Vincelette, Antony Prabhu, Dario Magaletti, Chunying Yang, Weimin Li, Amit Kulkarni, Oliver Alexander Hampton, John M Koomen, William R Roush, Andrii Monastyrskyi, Anders E Berglund, Ariosto S Silva, John L Cleveland, Kenneth H Shain
CK1δ/CK1ε Signaling Sustains Mitochondrial Metabolism and Cell Survival in Multiple Myeloma. Cancer research (2023)
Jun Yong Choi, Yoshihiko Noguchi, James M Alburger, Simon Bayle, Eugene Chung, Wayne Grant, Apirat Chaikuad, Stefan Knapp, Derek R Duckett, William R Roush
Structure-Based Development of Isoform-Selective Inhibitors of Casein Kinase 1ε vs Casein Kinase 1δ. Journal of medicinal chemistry (2023)
Dobeen Hwang, Napon Nilchan, HaJeung Park, Raktim N Roy, William R Roush, Christoph Rader
Sculpting a Uniquely Reactive Cysteine Residue for Site-Specific Antibody Conjugation. Bioconjugate chemistry 33 (6) (2022)
Chen Hao Lo, Gemma Shay, Jeremy J McGuire, Tao Li, Kenneth H Shain, Jun Yong Choi, Rita Fuerst, William R Roush, Anna M Knapinska, Gregg B Fields, Conor C Lynch
Host-Derived Matrix Metalloproteinase-13 Activity Promotes Multiple Myeloma-Induced Osteolysis and Reduces Overall Survival. Cancer research 81 (9) (2021)
Napon Nilchan, James M Alburger, William R Roush, Christoph Rader
An Engineered Arginine Residue of Unusual pH-Sensitive Reactivity Facilitates Site-Selective Antibody Conjugation. Biochemistry 60 (14) (2021)
Adéla Jílková, Petra Rubešová, Jindřich Fanfrlík, Pavla Fajtová, Pavlína Řezáčová, Jiří Brynda, Martin Lepsik, Helena Mertlíková-Kaiserová, Cory D Emal, Adam R Renslo, William R Roush, Martin Horn, Conor R Caffrey, Michael Mareš
Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors. ACS infectious diseases 7 (5) (2020)
Francesca Vena, Simon Bayle, Ainhoa Nieto, Victor Quereda, Massimiliano Aceti, Sylvia M Frydman, Samer S Sansil, Wayne Grant, Andrii Monastyrskyi, Patricia McDonald, William R Roush, Mingxiang Teng, Derek Duckett
Targeting Casein Kinase 1 Delta Sensitizes Pancreatic and Bladder Cancer Cells to Gemcitabine Treatment by Upregulating Deoxycytidine Kinase. Molecular cancer therapeutics 19 (8) (2020)
Claudia Magalhaes Calvet, Jun Yong Choi, Diane Thomas, Brian Suzuki, Ken Hirata, Sharon Lostracco-Johnson, Liliane Batista de Mesquita, Alanderson Nogueira, Marcelo Meuser-Batista, Tatiana Araujo Silva, Jair Lage Siqueira-Neto, William R Roush, Mirian Claudia de Souza Pereira, James H McKerrow, Larissa M Podust
4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infection. PLoS neglected tropical diseases 11 (12) (2017)
Manishabrata Bhowmick, Dorota Tokmina-Roszyk, Lillian Onwuha-Ekpete, Kelli Harmon, Trista Robichaud, Rita Fuerst, Roma Stawikowska, Bjorn Steffensen, William R Roush, Hector R Wong, Gregg B Fields
Second Generation Triple-Helical Peptide Inhibitors of Matrix Metalloproteinases. Journal of medicinal chemistry 60 (9) (2017)
Christophe Allais, William R Roush
Enantio- and Diastereoselective Synthesis of 1,5-syn-(Z)-Amino Alcohols via Imine Double Allylboration: Synthesis of trans-1,2,3,6-Tetrahydropyridines and Total Synthesis of Andrachcine. Organic letters 19 (10) (2017)
Jeremy W Mason, Cullen L Schmid, Laura M Bohn, William R Roush
Stolonidiol: Synthesis, Target Identification, and Mechanism for Choline Acetyltransferase Activation. Journal of the American Chemical Society 139 (16) (2017)
Jun Yong Choi, Rita Fuerst, Anna M Knapinska, Alexander B Taylor, Lyndsay Smith, Xiaohang Cao, P John Hart, Gregg B Fields, William R Roush
Structure-Based Design and Synthesis of Potent and Selective Matrix Metalloproteinase 13 Inhibitors. Journal of medicinal chemistry 60 (13) (2017)