Melanie Hinkel

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 9

Top Topics

Acute Myeloid Leukemia

Top Venues

Cancer research communications

Nature genetics

Future medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Robert J Norgard, Pratha Budhani, Sarah A O'Brien, Youli Xia, Jessica N Egan, Brianna Flynn, Joshua R Tagore, Joseph Seco, Gregory W Peet, Ania Mikucka, Ruby Wasti, Li-Chuan Chan, Melanie Hinkel, Sandra Martinez-Morilla, Jeanine Pignatelli, Francesca Trapani, Emily Corse, Di Feng, Kaja Kostyrko, Marco H Hofmann, Kang Liu, Abhishek S Kashyap
Reshaping the Tumor Microenvironment of KRASG12D Pancreatic Ductal Adenocarcinoma with Combined SOS1 and MEK Inhibition for Improved Immunotherapy Response. Cancer research communications 4 (6) (2024)
Robert J Norgard, Pratha Budhani, Sarah A O'Brien, Youli Xia, Jessica N Egan, Brianna Flynn, Joshua R Tagore, Joseph Seco, Gregory W Peet, Ania Mikucka, Ruby Wasti, Li-Chuan Chan, Melanie Hinkel, Sandra Martinez-Morilla, Jeanine Pignatelli, Francesca Trapani, Emily Corse, Di Feng, Kaja Kostyrko, Marco H Hofmann, Kang Liu, Abhishek S Kashyap
Reshaping the Tumor Microenvironment of KRASG12D Pancreatic Ductal Adenocarcinoma with combined SOS1 and MEK Inhibition for Improved Immunotherapy Response. Cancer research communications (2024)
Robert J Norgard, Pratha Budhani, Sarah A O'Brien, Youli Xia, Jessica N Egan, Brianna Flynn, Joshua R Tagore, Joseph Seco, Gregory W Peet, Ania Mikucka, Ruby Wasti, Li-Chuan Chan, Melanie Hinkel, Sandra Martinez-Morilla, Jeanine Pignatelli, Francesca Trapani, Emily Corse, Di Feng, Kaja Kostyrko, Marco H Hofmann, Kang Liu, Abhishek S Kashyap
Reshaping the Tumor Microenvironment of KRASG12D Pancreatic Ductal Adenocarcinoma with combined SOS1 and MEK Inhibition for Improved Immunotherapy Response. Cancer research communications (2024)
Venu Thatikonda, Hengyu Lu, Sabine Jurado, Kaja Kostyrko, Christopher A Bristow, Christoph Albrecht, Donát Alpár, Heribert Arnhof, Oliver Bergner, Karin Bosch, Ningping Feng, Sisi Gao, Daniel Gerlach, Michael Gmachl, Melanie Hinkel, Simone Lieb, Astrid Jeschko, Annette A Machado, Thomas Madensky, Ethan D Marszalek, Mikhila Mahendra, Gabriella Melo-Zainzinger, Jessica M Molkentine, Philipp A Jaeger, David H Peng, Robyn L Schenk, Alexey Sorokin, Sandra Strauss, Francesca Trapani, Edmund S Kopetz, Christopher P Vellano, Mark Petronczki, Norbert Kraut, Timothy P Heffernan, Joseph R Marszalek, Mark Pearson, Irene C Waizenegger, Marco H Hofmann
Co-targeting SOS1 enhances the antitumor effects of KRAS G12C inhibitors by addressing intrinsic and acquired resistance. Nature cancer (2024)
Venu Thatikonda, Hengyu Lu, Sabine Jurado, Kaja Kostyrko, Christopher A Bristow, Christoph Albrecht, Donát Alpár, Heribert Arnhof, Oliver Bergner, Karin Bosch, Ningping Feng, Sisi Gao, Daniel Gerlach, Michael Gmachl, Melanie Hinkel, Simone Lieb, Astrid Jeschko, Annette A Machado, Thomas Madensky, Ethan D Marszalek, Mikhila Mahendra, Gabriella Melo-Zainzinger, Jessica M Molkentine, Philipp A Jaeger, David H Peng, Robyn L Schenk, Alexey Sorokin, Sandra Strauss, Francesca Trapani, Edmund S Kopetz, Christopher P Vellano, Mark Petronczki, Norbert Kraut, Timothy P Heffernan, Joseph R Marszalek, Mark Pearson, Irene C Waizenegger, Marco H Hofmann
Co-targeting SOS1 enhances the antitumor effects of KRAS G12C inhibitors by addressing intrinsic and acquired resistance. Nature cancer (2024)
Robert J Norgard, Pratha Budhani, Sarah A O'Brien, Youli Xia, Jessica N Egan, Brianna Flynn, Joshua R Tagore, Joseph Seco, Gregory W Peet, Ania Mikucka, Ruby Wasti, Li-Chuan Chan, Melanie Hinkel, Sandra Martinez-Morilla, Jeanine Pignatelli, Francesca Trapani, Emily Corse, Di Feng, Kaja Kostyrko, Marco H Hofmann, Kang Liu, Abhishek S Kashyap
Reshaping the Tumor Microenvironment of KRASG12D Pancreatic Ductal Adenocarcinoma with Combined SOS1 and MEK Inhibition for Improved Immunotherapy Response. Cancer research communications 4 (6) (2024)
Robert J Norgard, Pratha Budhani, Sarah A O'Brien, Youli Xia, Jessica N Egan, Brianna Flynn, Joshua R Tagore, Joseph Seco, Gregory W Peet, Ania Mikucka, Ruby Wasti, Li-Chuan Chan, Melanie Hinkel, Sandra Martinez-Morilla, Jeanine Pignatelli, Francesca Trapani, Emily Corse, Di Feng, Kaja Kostyrko, Marco H Hofmann, Kang Liu, Abhishek S Kashyap
Reshaping the Tumor Microenvironment of KRASG12D Pancreatic Ductal Adenocarcinoma with combined SOS1 and MEK Inhibition for Improved Immunotherapy Response. Cancer research communications (2024)
Dirk Kessler, Andreas Bergner, Jark Böttcher, Gerhard Fischer, Sandra Döbel, Melanie Hinkel, Barbara Müllauer, Alexander Weiss-Puxbaum, Darryl B McConnell
Drugging all RAS isoforms with one pocket. Future medicinal chemistry 12 (21) (2020)
Sandra Schick, André Figueiredo Rendeiro, Kathrin Runggatscher, Anna Ringler, Bernd Boidol, Melanie Hinkel, Peter Májek, Loan Vulliard, Thomas Penz, Katja Parapatics, Christian Schmidl, J Formula See Text Rg Menche, Guido Boehmelt, Mark Petronczki, André C Müller, Christoph Bock, Stefan Kubicek
Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers. Nature genetics 51 (9) (2019)