Edmund S Kopetz (Scott E Kopetz, Scott Kopetz)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 96

Top Topics

Epidermal Growth Factor Receptor

Top Venues

Clinical cancer research : an official journal of the American Association for Cancer Research

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Nature medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Yasutoshi Kuboki, Marwan Fakih, John H Strickler, Rona Yaeger, Toshiki Masuishi, Edward J Kim, Christine M Bestvina, Edmund S Kopetz, Gerald S Falchook, Corey Langer, John Krauss, Sonam Puri, Panli Cardona, Emily Chan, Tracy Varrieur, Lata Mukundan, Abraham Anderson, Qui Tran, David S Hong
Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial. Nature medicine 30 (1) (2024)
Neal Bhutiani, Mahmoud M G Yousef, Abdelrahman M G Yousef, Mohammad A Zeineddine, Mark Knafl, Olivia Ratliff, Uditha P Fernando, Anastasia Turin, Fadl A Zeineddine, Jeff Jin, Kristin Alfaro-Munoz, Drew Goldstein, George J Chang, Edmund S Kopetz, John Paul Shen, Abhineet Uppal
Automated, High-Throughput Platform to Generate a High-Reliability, Comprehensive Rectal Cancer Database. JCO clinical cancer informatics 8 (2024)
Rona Yaeger, Nataliya V Uboha, Meredith S Pelster, Tanios S Bekaii-Saab, Minal Barve, Joel Saltzman, Joshua K Sabari, Julio Antonio Peguero, Andrew Scott Paulson, Pasi A Janne, Marcia Roxana Cruz-Correa, Kenna Anderes, Karen Velastegui, Xiaohong Yan, Hirak Der-Torossian, Samuel J Klempner, Edmund S Kopetz
Efficacy and Safety of Adagrasib plus Cetuximab in Patients with KRASG12C-Mutated Metastatic Colorectal Cancer. Cancer discovery (2024)
Kangyu Lin, Saikat Chowdhury, Mohammad A Zeineddine, Fadl A Zeineddine, Nicholas J Hornstein, Oscar Eduardo Villarreal, Dipen Maheshbhai Maru, Cara L Haymaker, Jean-Nicholas Vauthey, George J Chang, Elena Bogatenkova, David G Menter, Edmund S Kopetz, John Paul Shen
Identification of Colorectal Cancer Cell Stemness from Single-Cell RNA Sequencing. Molecular cancer research : MCR 22 (4) (2024)
Yasutoshi Kuboki, Marwan Fakih, John H Strickler, Rona Yaeger, Toshiki Masuishi, Edward J Kim, Christine M Bestvina, Edmund S Kopetz, Gerald S Falchook, Corey Langer, John Krauss, Sonam Puri, Panli Cardona, Emily Chan, Tracy Varrieur, Lata Mukundan, Abraham Anderson, Qui Tran, David S Hong
Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial. Nature medicine 30 (1) (2024)
Saikat Chowdhury, Joanne Xiu, Jennifer R Ribeiro, Theodore Nicolaides, Jian Zhang, W Michael Korn, Kelsey A Poorman, Heinz-Josef Lenz, John L Marshall, Matthew J Oberley, George W Sledge, David Spetzler, Edmund S Kopetz, John Paul Shen
Consensus molecular subtyping of metastatic colorectal cancer expands biomarker-directed therapeutic benefit for patients with CMS1 and CMS2 tumors. British journal of cancer (2024)
Venu Thatikonda, Hengyu Lu, Sabine Jurado, Kaja Kostyrko, Christopher A Bristow, Christoph Albrecht, Donát Alpár, Heribert Arnhof, Oliver Bergner, Karin Bosch, Ningping Feng, Sisi Gao, Daniel Gerlach, Michael Gmachl, Melanie Hinkel, Simone Lieb, Astrid Jeschko, Annette A Machado, Thomas Madensky, Ethan D Marszalek, Mikhila Mahendra, Gabriella Melo-Zainzinger, Jessica M Molkentine, Philipp A Jaeger, David H Peng, Robyn L Schenk, Alexey Sorokin, Sandra Strauss, Francesca Trapani, Edmund S Kopetz, Christopher P Vellano, Mark Petronczki, Norbert Kraut, Timothy P Heffernan, Joseph R Marszalek, Mark Pearson, Irene C Waizenegger, Marco H Hofmann
Co-targeting SOS1 enhances the antitumor effects of KRAS G12C inhibitors by addressing intrinsic and acquired resistance. Nature cancer (2024)
Christopher E Whitehead, Elizabeth K Ziemke, Christy L Frankowski-McGregor, Rachel A Mumby, June Chung, Jinju Li, Nathaniel Osher, Oluwadara Coker, Veerabhadran Baladandayuthapani, Edmund S Kopetz, Judith S Sebolt-Leopold
A first-in-class selective inhibitor of EGFR and PI3K offers a single-molecule approach to targeting adaptive resistance. Nature cancer (2024)
Akram Yazdani, Azam Yazdani, Raul Mendez-Giraldez, Gianluigi Pillonetto, Esmat Samiei, Reza Hadi, Heinz-Josef Lenz, Alan Venook, Ahmad Samiei, Andrew B Nixon, Joseph Lucci, Edmund S Kopetz, Monica Bertagnolli, Charles Perou, Federico Innocenti
Gene expression biomarkers differentiate overall survival of colorectal cancer upon targeted therapies. Research square (2024)
Jeffrey A Klomp, Jennifer E Klomp, Clint A Stalnecker, Kirsten L Bryant, A Cole Edwards, Kristina Drizyte-Miller, Priya S Hibshman, J Nathaniel Diehl, Ye S Lee, Alexis J Morales, Khalilah E Taylor, Sen Peng, Nhan L Tran, Laura E Herring, Alex W Prevatte, Natalie K Barker, Laura D Hover, Jill Hallin, Saikat Chowdhury, Oluwadara Coker, Hey Min Lee, Craig M Goodwin, Prson Gautam, Peter Olson, James G Christensen, John Paul Shen, Edmund S Kopetz, Lee M Graves, Kian-Huat Lim, Andrea Wang-Gillam, Krister Wennerberg, Adrienne D Cox, Channing J Der
Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers. Science (New York, N.Y.) 384 (6700) (2024)
Christopher E Whitehead, Elizabeth K Ziemke, Christy L Frankowski-McGregor, Rachel A Mumby, June Chung, Jinju Li, Nathaniel Osher, Oluwadara Coker, Veerabhadran Baladandayuthapani, Edmund S Kopetz, Judith S Sebolt-Leopold
A first-in-class selective inhibitor of EGFR and PI3K offers a single-molecule approach to targeting adaptive resistance. Nature cancer 5 (8) (2024)
Patrick G Pilié, Virginia Giuliani, Wei-Lien Wang, Daniel J McGrail, Christopher A Bristow, Natalie Yan Li Ngoi, Keith Kyewalabye, Khalida M Wani, Hung Le, Erick Campbell, Nora S Sanchez, Dong Yang, Jinesh S Gheeya, Rohit Vivek Goswamy, Vijaykumar Holla, Kenna Rael Shaw, Funda Meric-Bernstam, Chiu-Yi Liu, XiaoYan Ma, Ningping Feng, Annette A Machado, Jennifer P Bardenhagen, Christopher P Vellano, Joseph R Marszalek, Eeson Rajendra, Desiree Piscitello, Timothy I Johnson, Maria Likhatcheva, Elias Elinati, Jayesh Majithiya, Joana Neves, Vera Grinkevich, Marco Ranzani, Marina Roy Luzarraga, Marie Boursier, Lucy Armstrong, Lerin Geo, Giorgia Lillo, Wai Yiu Tse, Alexander J F Lazar, Edmund S Kopetz, Mary K Geck Do, Sarah Lively, Michael G Johnson, Helen M R Robinson, Graeme C M Smith, Christopher L Carroll, Maria Emilia Di Francesco, Philip Jones, Timothy P Heffernan, Timothy Anthony Yap
Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Yasutoshi Kuboki, Marwan Fakih, John H Strickler, Rona Yaeger, Toshiki Masuishi, Edward J Kim, Christine M Bestvina, Edmund S Kopetz, Gerald S Falchook, Corey Langer, John Krauss, Sonam Puri, Panli Cardona, Emily Chan, Tracy Varrieur, Lata Mukundan, Abraham Anderson, Qui Tran, David S Hong
Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial. Nature medicine 30 (1) (2024)
Rona Yaeger, Nataliya V Uboha, Meredith S Pelster, Tanios S Bekaii-Saab, Minal Barve, Joel Saltzman, Joshua K Sabari, Julio Antonio Peguero, Andrew Scott Paulson, Pasi A Janne, Marcia Roxana Cruz-Correa, Kenna Anderes, Karen Velastegui, Xiaohong Yan, Hirak Der-Torossian, Samuel J Klempner, Edmund S Kopetz
Efficacy and Safety of Adagrasib plus Cetuximab in Patients with KRASG12C-Mutated Metastatic Colorectal Cancer. Cancer discovery 14 (6) (2024)
Rona Yaeger, Nataliya V Uboha, Meredith S Pelster, Tanios S Bekaii-Saab, Minal Barve, Joel Saltzman, Joshua K Sabari, Julio Antonio Peguero, Andrew Scott Paulson, Pasi A Janne, Marcia Roxana Cruz-Correa, Kenna Anderes, Karen Velastegui, Xiaohong Yan, Hirak Der-Torossian, Samuel J Klempner, Edmund S Kopetz
Efficacy and Safety of Adagrasib plus Cetuximab in Patients with KRASG12C-Mutated Metastatic Colorectal Cancer. Cancer discovery 14 (6) (2024)
Venu Thatikonda, Hengyu Lu, Sabine Jurado, Kaja Kostyrko, Christopher A Bristow, Christoph Albrecht, Donát Alpár, Heribert Arnhof, Oliver Bergner, Karin Bosch, Ningping Feng, Sisi Gao, Daniel Gerlach, Michael Gmachl, Melanie Hinkel, Simone Lieb, Astrid Jeschko, Annette A Machado, Thomas Madensky, Ethan D Marszalek, Mikhila Mahendra, Gabriella Melo-Zainzinger, Jessica M Molkentine, Philipp A Jaeger, David H Peng, Robyn L Schenk, Alexey Sorokin, Sandra Strauss, Francesca Trapani, Edmund S Kopetz, Christopher P Vellano, Mark Petronczki, Norbert Kraut, Timothy P Heffernan, Joseph R Marszalek, Mark Pearson, Irene C Waizenegger, Marco H Hofmann
Co-targeting SOS1 enhances the antitumor effects of KRAS G12C inhibitors by addressing intrinsic and acquired resistance. Nature cancer (2024)
Vahid Bahrambeigi, Jaewon J Lee, Vittorio Branchi, Kimal I Rajapakshe, Zhichao Xu, Naishu Kui, Jason T Henry, Wang Kun, Bret M Stephens, Sarah Dhebat, Mark W Hurd, Ryan Sun, Peng Yang, Eytan Ruppin, Wenyi Wang, Edmund S Kopetz, Anirban Maitra, Paola A Guerrero
Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-specific Transcriptome and Molecular Subtype. Cancer research (2024)
Jeffrey A Klomp, Jennifer E Klomp, Clint A Stalnecker, Kirsten L Bryant, A Cole Edwards, Kristina Drizyte-Miller, Priya S Hibshman, J Nathaniel Diehl, Ye S Lee, Alexis J Morales, Khalilah E Taylor, Sen Peng, Nhan L Tran, Laura E Herring, Alex W Prevatte, Natalie K Barker, Laura D Hover, Jill Hallin, Alexey Sorokin, Preeti Marie Kanikarla, Saikat Chowdhury, Oluwadara Coker, Hey Min Lee, Craig M Goodwin, Prson Gautam, Peter Olson, James G Christensen, John Paul Shen, Edmund S Kopetz, Lee M Graves, Kian-Huat Lim, Andrea Wang-Gillam, Krister Wennerberg, Adrienne D Cox, Channing J Der
Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers. Science (New York, N.Y.) 384 (6700) (2024)
Patrick G Pilié, Virginia Giuliani, Wei-Lien Wang, Daniel J McGrail, Christopher A Bristow, Natalie Yan Li Ngoi, Keith Kyewalabye, Khalida M Wani, Hung Le, Erick Campbell, Nora S Sanchez, Dong Yang, Jinesh S Gheeya, Rohit Vivek Goswamy, Vijaykumar Holla, Kenna Rael Shaw, Funda Meric-Bernstam, Chiu-Yi Liu, XiaoYan Ma, Ningping Feng, Annette A Machado, Jennifer P Bardenhagen, Christopher P Vellano, Joseph R Marszalek, Eeson Rajendra, Desiree Piscitello, Timothy I Johnson, Maria Likhatcheva, Elias Elinati, Jayesh Majithiya, Joana Neves, Vera Grinkevich, Marco Ranzani, Marina Roy Luzarraga, Marie Boursier, Lucy Armstrong, Lerin Geo, Giorgia Lillo, Wai Yiu Tse, Alexander J F Lazar, Edmund S Kopetz, Mary K Geck Do, Sarah Lively, Michael G Johnson, Helen M R Robinson, Graeme C M Smith, Christopher L Carroll, Maria Emilia Di Francesco, Philip Jones, Timothy P Heffernan, Timothy Anthony Yap
Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Vahid Bahrambeigi, Jaewon J Lee, Vittorio Branchi, Kimal I Rajapakshe, Zhichao Xu, Naishu Kui, Jason T Henry, Wang Kun, Bret M Stephens, Sarah Dhebat, Mark W Hurd, Ryan Sun, Peng Yang, Eytan Ruppin, Wenyi Wang, Edmund S Kopetz, Anirban Maitra, Paola A Guerrero
Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-specific Transcriptome and Molecular Subtype. Cancer research (2024)
Patrick G Pilié, Virginia Giuliani, Wei-Lien Wang, Daniel J McGrail, Christopher A Bristow, Natalie Yan Li Ngoi, Keith Kyewalabye, Khalida M Wani, Hung Le, Erick Campbell, Nora S Sanchez, Dong Yang, Jinesh S Gheeya, Rohit Vivek Goswamy, Vijaykumar Holla, Kenna Rael Shaw, Funda Meric-Bernstam, Chiu-Yi Liu, XiaoYan Ma, Ningping Feng, Annette A Machado, Jennifer P Bardenhagen, Christopher P Vellano, Joseph R Marszalek, Eeson Rajendra, Desiree Piscitello, Timothy I Johnson, Maria Likhatcheva, Elias Elinati, Jayesh Majithiya, Joana Neves, Vera Grinkevich, Marco Ranzani, Marina Roy Luzarraga, Marie Boursier, Lucy Armstrong, Lerin Geo, Giorgia Lillo, Wai Yiu Tse, Alexander J F Lazar, Edmund S Kopetz, Mary K Geck Do, Sarah Lively, Michael G Johnson, Helen M R Robinson, Graeme C M Smith, Christopher L Carroll, Maria Emilia Di Francesco, Philip Jones, Timothy P Heffernan, Timothy Anthony Yap
Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Jeffrey A Klomp, Jennifer E Klomp, Clint A Stalnecker, Kirsten L Bryant, A Cole Edwards, Kristina Drizyte-Miller, Priya S Hibshman, J Nathaniel Diehl, Ye S Lee, Alexis J Morales, Khalilah E Taylor, Sen Peng, Nhan L Tran, Laura E Herring, Alex W Prevatte, Natalie K Barker, Laura D Hover, Jill Hallin, Saikat Chowdhury, Oluwadara Coker, Hey Min Lee, Craig M Goodwin, Prson Gautam, Peter Olson, James G Christensen, John Paul Shen, Edmund S Kopetz, Lee M Graves, Kian-Huat Lim, Andrea Wang-Gillam, Krister Wennerberg, Adrienne D Cox, Channing J Der
Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers. Science (New York, N.Y.) 384 (6700) (2024)
Hey Min Lee, Ajay Kumar Saw, Van Karlyle Morris, Stefania Napolitano, Christopher A Bristow, Sanjana Srinivasan, Michael D Peoples, Alexey V Sorokin, Preeti Kanikarla, Jonathan Schulz, Anand Kamal Singh, Christopher J Terranova, Oluwadara Coker, Abhinav K Jain, Edmund S Kopetz, Kunal Rai
Epigenome reprogramming through H3K27 and H3K4 trimethylation as a resistance mechanism to DNA methylation inhibition in BRAFV600E-mutated colorectal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Akram Yazdani, Azam Yazdani, Raul Mendez-Giraldez, Gianluigi Pillonetto, Esmat Samiei, Reza Hadi, Heinz-Josef Lenz, Alan Venook, Ahmad Samiei, Andrew B Nixon, null null, Edmund S Kopetz, Monica Bertagnolli, Charles Perou, Federico Innocenti
Gene expression biomarkers differentiate overall survival of colorectal cancer upon targeted therapies. Research square (2024)
Patrick G Pilié, Virginia Giuliani, Wei-Lien Wang, Daniel J McGrail, Christopher A Bristow, Natalie Yan Li Ngoi, Keith Kyewalabye, Khalida M Wani, Hung Le, Erick Campbell, Nora S Sanchez, Dong Yang, Jinesh S Gheeya, Rohit Vivek Goswamy, Vijaykumar Holla, Kenna Rael Shaw, Funda Meric-Bernstam, Chiu-Yi Liu, XiaoYan Ma, Ningping Feng, Annette A Machado, Jennifer P Bardenhagen, Christopher P Vellano, Joseph R Marszalek, Eeson Rajendra, Desiree Piscitello, Timothy I Johnson, Maria Likhatcheva, Elias Elinati, Jayesh Majithiya, Joana Neves, Vera Grinkevich, Marco Ranzani, Marina Roy Luzarraga, Marie Boursier, Lucy Armstrong, Lerin Geo, Giorgia Lillo, Wai Yiu Tse, Alexander J F Lazar, Edmund S Kopetz, Mary K Geck Do, Sarah Lively, Michael G Johnson, Helen M R Robinson, Graeme C M Smith, Christopher L Carroll, Maria Emilia Di Francesco, Philip Jones, Timothy P Heffernan, Timothy Anthony Yap
Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Christopher E Whitehead, Elizabeth K Ziemke, Christy L Frankowski-McGregor, Rachel A Mumby, June Chung, Jinju Li, Nathaniel Osher, Oluwadara Coker, Veerabhadran Baladandayuthapani, Edmund S Kopetz, Judith S Sebolt-Leopold
A first-in-class selective inhibitor of EGFR and PI3K offers a single-molecule approach to targeting adaptive resistance. Nature cancer 5 (8) (2024)
Rona Yaeger, Nataliya V Uboha, Meredith S Pelster, Tanios S Bekaii-Saab, Minal Barve, Joel Saltzman, Joshua K Sabari, Julio Antonio Peguero, Andrew Scott Paulson, Pasi A Janne, Marcia Roxana Cruz-Correa, Kenna Anderes, Karen Velastegui, Xiaohong Yan, Hirak Der-Torossian, Samuel J Klempner, Edmund S Kopetz
Efficacy and Safety of Adagrasib plus Cetuximab in Patients with KRASG12C-Mutated Metastatic Colorectal Cancer. Cancer discovery 14 (6) (2024)
Yasutoshi Kuboki, Marwan Fakih, John H Strickler, Rona Yaeger, Toshiki Masuishi, Edward J Kim, Christine M Bestvina, Edmund S Kopetz, Gerald S Falchook, Corey Langer, John Krauss, Sonam Puri, Panli Cardona, Emily Chan, Tracy Varrieur, Lata Mukundan, Abraham Anderson, Qui Tran, David S Hong
Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial. Nature medicine 30 (1) (2024)
Christopher E Whitehead, Elizabeth K Ziemke, Christy L Frankowski-McGregor, Rachel A Mumby, June Chung, Jinju Li, Nathaniel Osher, Oluwadara Coker, Veerabhadran Baladandayuthapani, Edmund S Kopetz, Judith S Sebolt-Leopold
A first-in-class selective inhibitor of EGFR and PI3K offers a single-molecule approach to targeting adaptive resistance. Nature cancer 5 (8) (2024)
Patrick G Pilié, Virginia Giuliani, Wei-Lien Wang, Daniel J McGrail, Christopher A Bristow, Natalie Yan Li Ngoi, Keith Kyewalabye, Khalida M Wani, Hung Le, Erick Campbell, Nora S Sanchez, Dong Yang, Jinesh S Gheeya, Rohit Vivek Goswamy, Vijaykumar Holla, Kenna Rael Shaw, Funda Meric-Bernstam, Chiu-Yi Liu, XiaoYan Ma, Ningping Feng, Annette A Machado, Jennifer P Bardenhagen, Christopher P Vellano, Joseph R Marszalek, Eeson Rajendra, Desiree Piscitello, Timothy I Johnson, Maria Likhatcheva, Elias Elinati, Jayesh Majithiya, Joana Neves, Vera Grinkevich, Marco Ranzani, Marina Roy Luzarraga, Marie Boursier, Lucy Armstrong, Lerin Geo, Giorgia Lillo, Wai Yiu Tse, Alexander J F Lazar, Edmund S Kopetz, Mary K Geck Do, Sarah Lively, Michael G Johnson, Helen M R Robinson, Graeme C M Smith, Christopher L Carroll, Maria Emilia Di Francesco, Philip Jones, Timothy P Heffernan, Timothy Anthony Yap
Ataxia-Telangiectasia Mutated (ATM) loss of function displays variant and tissue-specific differences across tumor types. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Jeffrey A Klomp, Jennifer E Klomp, Clint A Stalnecker, Kirsten L Bryant, A Cole Edwards, Kristina Drizyte-Miller, Priya S Hibshman, J Nathaniel Diehl, Ye S Lee, Alexis J Morales, Khalilah E Taylor, Sen Peng, Nhan L Tran, Laura E Herring, Alex W Prevatte, Natalie K Barker, Laura D Hover, Jill Hallin, Saikat Chowdhury, Oluwadara Coker, Hey Min Lee, Craig M Goodwin, Prson Gautam, Peter Olson, James G Christensen, John Paul Shen, Edmund S Kopetz, Lee M Graves, Kian-Huat Lim, Andrea Wang-Gillam, Krister Wennerberg, Adrienne D Cox, Channing J Der
Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers. Science (New York, N.Y.) 384 (6700) (2024)
Saikat Chowdhury, Joanne Xiu, Jennifer R Ribeiro, Theodore Nicolaides, Jian Zhang, W Michael Korn, Kelsey A Poorman, Heinz-Josef Lenz, John L Marshall, Matthew J Oberley, George W Sledge, David Spetzler, Edmund S Kopetz, John Paul Shen
Consensus molecular subtyping of metastatic colorectal cancer expands biomarker-directed therapeutic benefit for patients with CMS1 and CMS2 tumors. British journal of cancer (2024)
Rona Yaeger, Nataliya V Uboha, Meredith S Pelster, Tanios S Bekaii-Saab, Minal Barve, Joel Saltzman, Joshua K Sabari, Julio Antonio Peguero, Andrew Scott Paulson, Pasi A Janne, Marcia Roxana Cruz-Correa, Kenna Anderes, Karen Velastegui, Xiaohong Yan, Hirak Der-Torossian, Samuel J Klempner, Edmund S Kopetz
Efficacy and Safety of Adagrasib plus Cetuximab in Patients with KRASG12C-Mutated Metastatic Colorectal Cancer. Cancer discovery 14 (6) (2024)
Christopher E Whitehead, Elizabeth K Ziemke, Christy L Frankowski-McGregor, Rachel A Mumby, June Chung, Jinju Li, Nathaniel Osher, Oluwadara Coker, Veerabhadran Baladandayuthapani, Edmund S Kopetz, Judith S Sebolt-Leopold
A first-in-class selective inhibitor of EGFR and PI3K offers a single-molecule approach to targeting adaptive resistance. Nature cancer (2024)
Kangyu Lin, Saikat Chowdhury, Mohammad A Zeineddine, Fadl A Zeineddine, Nicholas J Hornstein, Oscar Eduardo Villarreal, Dipen Maheshbhai Maru, Cara L Haymaker, Jean-Nicholas Vauthey, George J Chang, Elena Bogatenkova, David G Menter, Edmund S Kopetz, John Paul Shen
Identification of Colorectal Cancer Cell Stemness from Single-Cell RNA Sequencing. Molecular cancer research : MCR 22 (4) (2024)
Yasutoshi Kuboki, Marwan Fakih, John H Strickler, Rona Yaeger, Toshiki Masuishi, Edward J Kim, Christine M Bestvina, Edmund S Kopetz, Gerald S Falchook, Corey Langer, John Krauss, Sonam Puri, Panli Cardona, Emily Chan, Tracy Varrieur, Lata Mukundan, Abraham Anderson, Qui Tran, David S Hong
Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial. Nature medicine (2024)
Yasutoshi Kuboki, Marwan Fakih, John H Strickler, Rona Yaeger, Toshiki Masuishi, Edward J Kim, Christine M Bestvina, Edmund S Kopetz, Gerald S Falchook, Corey Langer, John Krauss, Sonam Puri, Panli Cardona, Emily Chan, Tracy Varrieur, Lata Mukundan, Abraham Anderson, Qui Tran, David S Hong
Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial. Nature medicine 30 (1) (2024)
Vahid Bahrambeigi, Jaewon J Lee, Vittorio Branchi, Kimal I Rajapakshe, Zhichao Xu, Naishu Kui, Jason T Henry, Wang Kun, Bret M Stephens, Sarah Dhebat, Mark W Hurd, Ryan Sun, Peng Yang, Eytan Ruppin, Wenyi Wang, Edmund S Kopetz, Anirban Maitra, Paola A Guerrero
Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-Specific Transcriptome and Molecular Subtype. Cancer research 84 (10) (2024)
Yujie Jiang, Matthew D Montierth, Kaixian Yu, Shuangxi Ji, Shuai Guo, Quang Tran, Xiaoqian Liu, Seung Jun Shin, Shaolong Cao, Ruonan Li, Yuxin Tang, Tom Lesluyes, Edmund S Kopetz, Jaffer A Ajani, Pavlos Msaouel, Sumit K Subudhi, Ana Aparicio, Padmanee Sharma, John Paul Shen, Anil K Sood, Maxime Tarabichi, Jennifer R Wang, Marek Kimmel, Peter Van Loo, Hongtu Zhu, Wenyi Wang
Pan-cancer subclonal mutation analysis of 7,827 tumors predicts clinical outcome. bioRxiv : the preprint server for biology (2024)
Kangyu Lin, Saikat Chowdhury, Mohammad A Zeineddine, Fadl A Zeineddine, Nicholas J Hornstein, Oscar Eduardo Villarreal, Dipen Maheshbhai Maru, Cara L Haymaker, Jean-Nicholas Vauthey, George J Chang, Elena Bogatenkova, David G Menter, Edmund S Kopetz, John Paul Shen
Identification of Colorectal Cancer Cell Stemness from Single-Cell RNA Sequencing. Molecular cancer research : MCR 22 (4) (2024)
Yasutoshi Kuboki, Marwan Fakih, John H Strickler, Rona Yaeger, Toshiki Masuishi, Edward J Kim, Christine M Bestvina, Edmund S Kopetz, Gerald S Falchook, Corey Langer, John Krauss, Sonam Puri, Panli Cardona, Emily Chan, Tracy Varrieur, Lata Mukundan, Abraham Anderson, Qui Tran, David S Hong
Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial. Nature medicine 30 (1) (2024)
Yasutoshi Kuboki, Marwan Fakih, John H Strickler, Rona Yaeger, Toshiki Masuishi, Edward J Kim, Christine M Bestvina, Edmund S Kopetz, Gerald S Falchook, Corey Langer, John Krauss, Sonam Puri, Panli Cardona, Emily Chan, Tracy Varrieur, Lata Mukundan, Abraham Anderson, Qui Tran, David S Hong
Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C -mutated colorectal cancer: a phase 1b trial. Nature medicine 30 (1) (2024)
Kangyu Lin, Saikat Chowdhury, Mohammad A Zeineddine, Fadl A Zeineddine, Nicholas J Hornstein, Oscar Eduardo Villarreal, Dipen Maheshbhai Maru, Cara L Haymaker, Jean-Nicholas Vauthey, George J Chang, Elena Bogatenkova, David G Menter, Edmund S Kopetz, John Paul Shen
Identification of Colorectal Cancer Cell Stemness from Single-Cell RNA Sequencing. Molecular cancer research : MCR 22 (4) (2024)
Vahid Bahrambeigi, Jaewon J Lee, Vittorio Branchi, Kimal I Rajapakshe, Zhichao Xu, Naishu Kui, Jason T Henry, Wang Kun, Bret M Stephens, Sarah Dhebat, Mark W Hurd, Ryan Sun, Peng Yang, Eytan Ruppin, Wenyi Wang, Edmund S Kopetz, Anirban Maitra, Paola A Guerrero
Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-specific Transcriptome and Molecular Subtype. Cancer research (2024)
Vahid Bahrambeigi, Jaewon J Lee, Vittorio Branchi, Kimal I Rajapakshe, Zhichao Xu, Naishu Kui, Jason T Henry, Wang Kun, Bret M Stephens, Sarah Dhebat, Mark W Hurd, Ryan Sun, Peng Yang, Eytan Ruppin, Wenyi Wang, Edmund S Kopetz, Anirban Maitra, Paola A Guerrero
Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-Specific Transcriptome and Molecular Subtype. Cancer research 84 (10) (2024)
Akram Yazdani, Azam Yazdani, Raul Mendez-Giraldez, Gianluigi Pillonetto, Esmat Samiei, Reza Hadi, Heinz-Josef Lenz, Alan Venook, Ahmad Samiei, Andrew B Nixon, null null, Edmund S Kopetz, Monica Bertagnolli, Charles Perou, Federico Innocenti
Gene expression biomarkers differentiate overall survival of colorectal cancer upon targeted therapies. Research square (2024)
Jeffrey A Klomp, Jennifer E Klomp, Clint A Stalnecker, Kirsten L Bryant, A Cole Edwards, Kristina Drizyte-Miller, Priya S Hibshman, J Nathaniel Diehl, Ye S Lee, Alexis J Morales, Khalilah E Taylor, Sen Peng, Nhan L Tran, Laura E Herring, Alex W Prevatte, Natalie K Barker, Laura D Hover, Jill Hallin, Saikat Chowdhury, Oluwadara Coker, Hey Min Lee, Craig M Goodwin, Prson Gautam, Peter Olson, James G Christensen, John Paul Shen, Edmund S Kopetz, Lee M Graves, Kian-Huat Lim, Andrea Wang-Gillam, Krister Wennerberg, Adrienne D Cox, Channing J Der
Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers. Science (New York, N.Y.) 384 (6700) (2024)
Christopher E Whitehead, Elizabeth K Ziemke, Christy L Frankowski-McGregor, Rachel A Mumby, June Chung, Jinju Li, Nathaniel Osher, Oluwadara Coker, Veerabhadran Baladandayuthapani, Edmund S Kopetz, Judith S Sebolt-Leopold
A first-in-class selective inhibitor of EGFR and PI3K offers a single-molecule approach to targeting adaptive resistance. Nature cancer (2024)
Vahid Bahrambeigi, Jaewon J Lee, Vittorio Branchi, Kimal I Rajapakshe, Zhichao Xu, Naishu Kui, Jason T Henry, Wang Kun, Bret M Stephens, Sarah Dhebat, Mark W Hurd, Ryan Sun, Peng Yang, Eytan Ruppin, Wenyi Wang, Edmund S Kopetz, Anirban Maitra, Paola A Guerrero
Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-Specific Transcriptome and Molecular Subtype. Cancer research 84 (10) (2024)
Kanwal P S Raghav, Edmund S Kopetz, Ying Yuan
Reply to Y. Yu et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 41 (7) (2023)
Alexander I Spira, Michael S Wertheim, Edward J Kim, Benjamin Tan, Heinz-Josef Lenz, Petros Nikolinakos, Patricia L Rich, Genevieve Jehl, Andreas Machl, Rena Ito, James L Gulley, Edmund S Kopetz
Bintrafusp Alfa: A Bifunctional Fusion Protein Targeting PD-L1 and TGF-β, in Patients with Pretreated Colorectal Cancer: Results from a Phase I Trial. The oncologist 28 (2) (2023)
Susmita Ghosh, Fan Fan, Reid T Powell, Jason Roszik, Yongsung Park, Clifford Stephen, Manu Sebastian, Lin Tan, Alexey V Sorokin, Philip L Lorenzi, Edmund S Kopetz, Lee M Ellis, Rajat Bhattacharya
Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer. Molecular cancer therapeutics (2023)
Blessie Elizabeth Nelson, Apostolia M Tsimberidou, Xueyao Fu, Siqing Fu, Vivek Subbiah, Anil K Sood, Jordi Rodon, Daniel D Karp, George Blumenschein, Edmund S Kopetz, Shubham Pant, Sarina A Piha-Paul
A Phase I Trial of Bevacizumab and Temsirolimus in Combination With Valproic Acid in Advanced Solid Tumors. The oncologist (2023)
Kanwal P S Raghav, Edmund S Kopetz, Ying Yuan
Reply to Y. Yu et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 41 (7) (2023)
Saikat Chowdhury, Ria Gupta, Joshua Millstein, Kangyu Lin, Valsala Haridas, Mohammad A Zeineddine, Christine M Parseghian, Heinz-Josef Lenz, Edmund S Kopetz, John Paul Shen
Transcriptional Profiling and Consensus Molecular Subtype Assignment to Understand Response and Resistance to Anti-Epidermal Growth Factor Receptor Therapy in Colorectal Cancer. JCO precision oncology 7 (2023)
Kanwal P S Raghav, Jonathan M Loree, Edmund S Kopetz
PRESSING need of precision care in HER2-positive CRC: The ELEPHANT in the room. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Stefania Napolitano, Melanie Woods, Hey Min Lee, Vincenzo De Falco, Giulia Martini, Carminia Maria Della Corte, Erika Martinelli, Vincenzo Famiglietti, Davide Ciardiello, Amanda Anderson, Natalie Wall Fowlkes, Oscar Eduardo Villarreal, Alexey V Sorokin, Preeti Kanikarla, Oluwadara Coker, Van Karlyle Morris, Lucia Altucci, Josep Tabernero, Teresa Troiani, Fortunato Ciardiello, Edmund S Kopetz
Antitumor efficacy of dual blockade with encorafenib plus cetuximab in combination with chemotherapy in human BRAFV600E mutant colorectal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Kanwal P S Raghav, Edmund S Kopetz, Ying Yuan
Reply to Y. Yu et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 41 (7) (2023)
Kaysia Ludford, Won Jin Ho, Jane V Thomas, Kanwal P S Raghav, Mariela Blum Murphy, Nicole D Fleming, Michael S Lee, Brandon G Smaglo, Y Nancy You, Matthew M Tillman, Carlos Kamiya-Matsuoka, Selvi Thirumurthi, Craig Messick, Benny Johnson, Eduardo Vilar, Arvind N Dasari, Sarah M Shin, Alexei Hernandez, Xuan Yuan, Hongqui Yang, Wai Chin Foo, Wei Qiao, Dipen Maheshbhai Maru, Edmund S Kopetz, Michael James Overman
Neoadjuvant Pembrolizumab in Localized Microsatellite Instability High/Deficient Mismatch Repair Solid Tumors. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Stefania Napolitano, Aparna Raj Parikh, Jason T Henry, Christine M Parseghian, Jason Willis, Kanwal P S Raghav, Van Karlyle Morris, Benny Johnson, Bryan K Kee, Arvind N Dasari, Michael James Overman, Raja Luthra, Leylah M Drusbosky, Ryan B Corcoran, Edmund S Kopetz, Ryan Sun
Novel Clinical Tool to Estimate Risk of False-Negative KRAS Mutations in Circulating Tumor DNA Testing. JCO precision oncology 7 (2023)
Kanwal P S Raghav, Edmund S Kopetz, Ying Yuan
Reply to Y. Yu et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Wen-Hao Hsu, Kyle A LaBella, Yiyun Lin, Ping Xu, Rumi Lee, Rodney Cheng-En Hsieh, Lei Yang, Ashley Zhou, Jonathan M Blecher, Chang-Jiun Wu, Kangyu Lin, Xiaoying Shang, Shan Jiang, Denise J Spring, Yan Xia, Peiwen Chen, John Paul Shen, Edmund S Kopetz, Ronald A DePinho
Oncogenic KRAS drives lipo-fibrogenesis to promote angiogenesis and colon cancer progression. Cancer discovery (2023)
Kaysia Ludford, Won Jin Ho, Jane V Thomas, Kanwal P S Raghav, Mariela Blum Murphy, Nicole D Fleming, Michael S Lee, Brandon G Smaglo, Y Nancy You, Matthew M Tillman, Carlos Kamiya-Matsuoka, Selvi Thirumurthi, Craig Messick, Benny Johnson, Eduardo Vilar, Arvind N Dasari, Sarah M Shin, Alexei Hernandez, Xuan Yuan, Hongqui Yang, Wai Chin Foo, Wei Qiao, Dipen Maheshbhai Maru, Edmund S Kopetz, Michael James Overman
Neoadjuvant Pembrolizumab in Localized Microsatellite Instability High/Deficient Mismatch Repair Solid Tumors. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Kangyu Lin, Saikat Chowdhury, Mohammad A Zeineddine, Fadl A Zeineddine, Nicholas J Hornstein, Oscar Eduardo Villarreal, Dipen Maheshbhai Maru, Cara L Haymaker, Jean-Nicholas Vauthey, George J Chang, Elena Bogatenkova, David G Menter, Edmund S Kopetz, John Paul Shen
Identification of colorectal cancer cell stemness from single-cell RNA sequencing. Molecular cancer research : MCR (2023)
Kristen Simmons, Jane V Thomas, Kaysia Ludford, Jason A Willis, Victoria Serpas Higbie, Kanwal P S Raghav, Benny Johnson, Arvind N Dasari, Bryan K Kee, Christine M Parseghian, Michael S Lee, Phat H Le, Maria P Morelli, John Paul Shen, Alisha Bent, Eduardo Vilar, Robert A Wolff, Edmund S Kopetz, Michael James Overman, Van Karlyle Morris
Sustained Disease Control in Immune Checkpoint Blockade Responders with Microsatellite Instability-high Colorectal Cancer after Treatment Termination. Cancer research communications 3 (12) (2023)
Kristen Simmons, Jane V Thomas, Kaysia Ludford, Jason A Willis, Victoria Serpas Higbie, Kanwal P S Raghav, Benny Johnson, Arvind N Dasari, Bryan K Kee, Christine M Parseghian, Michael S Lee, Phat H Le, Maria P Morelli, John Paul Shen, Alisha Bent, Eduardo Vilar, Robert A Wolff, Edmund S Kopetz, Michael James Overman, Van Karlyle Morris
Sustained Disease Control in Immune Checkpoint Blockade Responders with Microsatellite Instability-high Colorectal Cancer after Treatment Termination. Cancer research communications 3 (12) (2023)
Isabella N Grabski, John Victor Heymach, Kenneth L Kehl, Edmund S Kopetz, Ken S Lau, Gregory J Riely, Deborah Schrag, Rona Yaeger, Rafael A Irizarry, Kevin M Haigis
Effects of KRAS genetic interactions on outcomes in cancers of the lung, pancreas, and colorectum. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2023)
Kristen Simmons, Jane V Thomas, Kaysia Ludford, Jason A Willis, Victoria Serpas Higbie, Kanwal P S Raghav, Benny Johnson, Arvind N Dasari, Bryan K Kee, Christine M Parseghian, Michael S Lee, Phat H Le, Maria P Morelli, John Paul Shen, Alisha Bent, Eduardo Vilar, Robert A Wolff, Edmund S Kopetz, Michael James Overman, Van Karlyle Morris
Sustained Disease Control in Immune Checkpoint Blockade Responders with Microsatellite Instability-high Colorectal Cancer after Treatment Termination. Cancer research communications 3 (12) (2023)
Alexander I Spira, Michael S Wertheim, Edward J Kim, Benjamin Tan, Heinz-Josef Lenz, Petros Nikolinakos, Patricia L Rich, Genevieve Jehl, Andreas Machl, Rena Ito, James L Gulley, Edmund S Kopetz
Bintrafusp Alfa: A Bifunctional Fusion Protein Targeting PD-L1 and TGF-β, in Patients with Pretreated Colorectal Cancer: Results from a Phase I Trial. The oncologist 28 (2) (2023)
Kristen Simmons, Jane V Thomas, Kaysia Ludford, Jason A Willis, Victoria Serpas Higbie, Kanwal P S Raghav, Benny Johnson, Arvind N Dasari, Bryan K Kee, Christine M Parseghian, Michael S Lee, Phat H Le, Maria P Morelli, John Paul Shen, Alisha Bent, Eduardo Vilar, Robert A Wolff, Edmund S Kopetz, Michael James Overman, Van Karlyle Morris
Sustained Disease Control in Immune Checkpoint Blockade Responders with Microsatellite Instability-high Colorectal Cancer after Treatment Termination. Cancer research communications 3 (12) (2023)
Christine M Parseghian, Ryan Sun, Melanie Woods, Stefania Napolitano, Hey Min Lee, Jumanah Alshenaifi, Jason A Willis, Shakayla Nunez, Kanwal P S Raghav, Van Karlyle Morris, John Paul Shen, Madhulika Eluri, Alexey Sorokin, Preeti Kanikarla, Eduardo Vilar, Marko Rehn, Agnes Ang, Teresa Troiani, Edmund S Kopetz
Resistance Mechanisms to Anti-Epidermal Growth Factor Receptor Therapy in RAS/RAF Wild-Type Colorectal Cancer Vary by Regimen and Line of Therapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)
Mohamed A Gouda, Dzifa Y Duose, Morten Lapin, Stephanie Zalles, Helen J Huang, Yuanxin Xi, Xiaofeng Zheng, Amira I Aldesoky, Alshimaa M Alhanafy, Mohamed A Shehata, Jing Wang, Edmund S Kopetz, Funda Meric-Bernstam, Ignacio I Wistuba, Rajyalakshmi Luthra, Filip Janku
Mutation-Agnostic Detection of Colorectal Cancer Using Liquid Biopsy-Based Methylation-Specific Signatures. The oncologist (2022)
Kyaw Zin Thein, Amadeo B Biter, Kimberly C Banks, Andrew W Duda, Jennifer Saam, Jason Roszik, Filip Janku, Ferdinandos Skoulidis, John Victor Heymach, Edmund S Kopetz, Funda Meric-Bernstam, David S Hong
Identification of KRAS G12C Mutations in Circulating Tumor DNA in Patients With Cancer. JCO precision oncology 6 (2022)
Madhulika Eluri, Edmund S Kopetz, Christine M Parseghian
Truncal dynamics may trump: serial ctDNA to predict early therapeutic response. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Anai Kothari, Michael G White, Oliver Peacock, Harmeet Kaur, Sarah M Palmquist, Nancy You, Melissa Taggart, Usama Salem, Michael Overman, Edmund S Kopetz, George J Chang
Pathological response following neoadjuvant immunotherapy in mismatch repair-deficient/microsatellite instability-high locally advanced, non-metastatic colorectal cancer. The British journal of surgery 109 (6) (2022)
Marwan G Fakih, Huakang Tu, Hil Hsu, Shivani Aggarwal, Emily Chan, Marko Rehn, Victoria Chia, Edmund S Kopetz
Real-World Study of Characteristics and Treatment Outcomes Among Patients with KRAS p.G12C-Mutated or Other KRAS Mutated Metastatic Colorectal Cancer. The oncologist 27 (8) (2022)
Alexander I Spira, Michael S Wertheim, Edward J Kim, Benjamin Tan, Heinz-Josef Lenz, Petros Nikolinakos, Patricia L Rich, Genevieve Jehl, Andreas Machl, Rena Ito, James L Gulley, Edmund S Kopetz
Bintrafusp Alfa: A Bifunctional Fusion Protein Targeting PD-L1 and TGF-β, in Patients with Pretreated Colorectal Cancer: Results from a Phase I Trial. The oncologist (2022)
Anai Kothari, Michael G White, Oliver Peacock, Harmeet Kaur, Sarah M Palmquist, Nancy You, Melissa Taggart, Usama Salem, Michael Overman, Edmund S Kopetz, George J Chang
Pathological response following neoadjuvant immunotherapy in mismatch repair-deficient/microsatellite instability-high locally advanced, non-metastatic colorectal cancer. The British journal of surgery (2022)
Matthew Dankner, Yifan Wang, Rouhi Fazelzad, Benny Johnson, Caroline A Nebhan, Ibiayi Dagogo-Jack, Nathaniel J Myall, Georg Richtig, Jillian Wilhelmina Paulina Bracht, Marco Gerlinger, Eiji Shinozaki, Takayuki Yoshino, Daisuke Kotani, Jason R Fangusaro, Oliver Gautschi, Julien Mazieres, Jeffrey A Sosman, Edmund S Kopetz, Vivek Subbiah, Michael A Davies, Anna L Groover, Ryan J Sullivan, Keith T Flaherty, Douglas B Johnson, Andrea Benedetti, David W Cescon, Anna Spreafico, George Zogopoulos, April A N Rose
Clinical Activity of Mitogen-Activated Protein Kinase-Targeted Therapies in Patients With Non-V600 BRAF-Mutant Tumors. JCO precision oncology 6 (2022)
Kanwal P S Raghav, Fang-Shu Ou, Alan P Venook, Federico Innocenti, Ryan Sun, Heinz-Josef Lenz, Edmund S Kopetz
Acquired Genomic Alterations on First-Line Chemotherapy With Cetuximab in Advanced Colorectal Cancer: Circulating Tumor DNA Analysis of the CALGB/SWOG-80405 Trial (Alliance). Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)
Shaolong Cao, Jennifer R Wang, Shuangxi Ji, Peng Yang, Yaoyi Dai, Shuai Guo, Matthew D Montierth, John Paul Shen, Xiao Zhao, Jingxiao Chen, Jaewon James Lee, Paola A Guerrero, Nicholas Spetsieris, Nikolai Engedal, Sinja Taavitsainen, Kaixian Yu, Julie Livingstone, Vinayak Bhandari, Shawna Marie Hubert, Najat C Daw, P Andrew Futreal, Eleni Efstathiou, Bora Lim, Andrea Viale, Jianjun Zhang, Matti Nykter, Bogdan A Czerniak, Powel H Brown, Charles Swanton, Pavlos Msaouel, Anirban Maitra, Edmund S Kopetz, Peter J Campbell, Terence P Speed, Paul C Boutros, Hongtu Zhu, Alfonso Urbanucci, Jonas Demeulemeester, Peter Van Loo, Wenyi Wang
Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression. Nature biotechnology 40 (11) (2022)
Alexey V Sorokin, Preeti Kanikarla Marie, Lea Bitner, Muddassir Syed, Melanie Woods, Ganiraju C Manyam, Lawrence N Kwong, Benny Johnson, Van Karlyle Morris, Philip Jones, David G Menter, Michael S Lee, Edmund S Kopetz
Targeting RAS Mutant Colorectal Cancer with Dual Inhibition of MEK and CDK4/6. Cancer research 82 (18) (2022)
Victoria Serpas Higbie, Jane E Rogers, Hyunsoo Hwang, Wei Qiao, Lianchun Xiao, Arvind N Dasari, Kerri Mola-Rudd, Van Karlyle Morris, Robert A Wolff, Kanwal P S Raghav, Ryan Huey, Christine M Parseghian, Jason A Willis, Edmund S Kopetz, Michael James Overman, Benny Johnson
Antibiotic Exposure Does Not Impact Immune Checkpoint Blockade Response in MSI-H/dMMR Metastatic Colorectal Cancer: A Single-Center Experience. The oncologist 27 (11) (2022)
Van Karlyle Morris, Edmund S Kopetz
Don't blame the messenger: lessons learned for cancer mRNA vaccines during the COVID-19 pandemic. Nature reviews. Cancer 22 (6) (2022)
Hamzah Abu-Sbeih, David Szafron, Ahmed A Elkafrawy, Victor Garcia-Rodriguez, Weijie Ma, Ann Xu, Shruti Khurana, Laith Numan, Ellie Chen, Ryan Goldstein, Adrianne Tsen, Yuanzun Peng, Mariela Blum Murphy, Edmund S Kopetz, Naruhiko Ikoma, Malek Shatila, Wei Qiao, Gottumukkala S Raju, William A Ross, Phillip S Ge, Emmanuel Coronel, Yinghong Wang
Endoscopy for the diagnosis and treatment of gastrointestinal bleeding caused by malignancy. Journal of gastroenterology and hepatology 37 (10) (2022)
Pashtoon Murtaza Kasi, Gordon Fehringer, Alexey Aleshin, Edmund S Kopetz
Reply to F. Dayyani et al. JCO precision oncology 6 (2022)
Benny Johnson, Edmund S Kopetz
Applying Precision to the Management of BRAF-Mutant Metastatic Colorectal Cancer. Targeted oncology 15 (5) (2021)
Mihnea Paul Dragomir, Edmund S Kopetz, Jaffer A Ajani, George Adrian Calin
Non-coding RNAs in GI cancers: from cancer hallmarks to clinical utility. Gut 69 (4) (2020)
Sherille D Bradley, Amjad H Talukder, Ivy Lai, Rebecca Davis, Hector Alvarez, Herve Tiriac, Minying Zhang, Yulun Chiu, Brenda Melendez, Kyle R Jackson, Arjun Katailiha, Heather M Sonnemann, Fenge Li, Yaan Kang, Na Qiao, Bih-Fang Pan, Philip L Lorenzi, Mark W Hurd, Elizabeth A Mittendorf, Christine B Peterson, Milind Javle, Christopher Bristow, Michael Kim, David A Tuveson, David H Hawke, Edmund S Kopetz, Robert A Wolff, Patrick Hwu, Anirban Maitra, Jason Roszik, Cassian Yee, Gregory Lizée
Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers. Nature communications 11 (1) (2020)
Arvind N Dasari, Van K Morris, Carmen J Allegra, Chloe Atreya, Al B Benson, Patrick Boland, Ki Chung, Mehmet S Copur, Ryan B Corcoran, Dustin A Deming, Andrea Dwyer, Maximillian Diehn, Cathy Eng, Thomas J George, Marc J Gollub, Rachel A Goodwin, Stanley R Hamilton, Jaclyn F Hechtman, Howard S Hochster, Theodore S Hong, Federico Innocenti, Atif Iqbal, Samuel A Jacobs, Hagen F Kennecke, James J Lee, Christopher H Lieu, Heinz-Josef Lenz, O Wolf Lindwasser, Clara Montagut, Bruno Odisio, Fang-Shu Ou, Laura Porter, Kanwal Raghav, Deborah Schrag, Aaron James Scott, Qian Shi, John H Strickler, Alan P Venook, Rona Yaeger, Greg Yothers, Y Nancy You, Jason A Zell, Edmund S Kopetz
ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal-Anal Task Forces whitepaper. Nature reviews. Clinical oncology 17 (12) (2020)
Jian Yang, Yuhua Gong, Vincent K Lam, Yan Shi, Yanfang Guan, Yanyan Zhang, Liyan Ji, Yongsheng Chen, Yongliang Zhao, Feng Qian, Jun Chen, Pingang Li, Fan Zhang, Jiayin Wang, Xuanping Zhang, Ling Yang, Edmund S Kopetz, P Andrew Futreal, Jianjun Zhang, Xin Yi, Xuefeng Xia, Pei-Wu Yu
Deep sequencing of circulating tumor DNA detects molecular residual disease and predicts recurrence in gastric cancer. Cell death & disease 11 (5) (2020)
Shailesh Advani, Edmund S Kopetz
Ongoing and future directions in the management of metastatic colorectal cancer: Update on clinical trials. Journal of surgical oncology 119 (5) (2019)
Lene Alifrangis, Rik Schoemaker, Niels J Skartved, Rikke Hald, Clara Montagut, Edmund S Kopetz, Josep Tabernero, Michael Kragh, Janet R Wade
Population pharmacokinetics and covariate analysis of Sym004, an antibody mixture against the epidermal growth factor receptor, in subjects with metastatic colorectal cancer and other solid tumors. Journal of pharmacokinetics and pharmacodynamics 47 (1) (2019)
Maliha Khan, Krittiya Korphaisarn, Aneeqa Saif, Wai C Foo, Edmund S Kopetz
Early-Onset Signet-Ring Cell Adenocarcinoma of the Colon: A Case Report and Review of the Literature. Case reports in oncological medicine 2017 (2017)
Ritesh Kumar, Jennifer L Herold, Deborah Schady, Jennifer S Davis, Edmund S Kopetz, Margarita Martinez-Moczygemba, Barbara E Murray, Fang Han, Yu Li, Evelyn Callaway, Robert S Chapkin, Wan-Mohaiza Dashwood, Roderick H Dashwood, Tia Berry, Chris Mackenzie, Yi Xu
Streptococcus gallolyticus subsp. gallolyticus promotes colorectal tumor development. PLoS pathogens 13 (7) (2017)
Amir Mehrvarz Sarshekeh, Shailesh Advani, Michael J Overman, Ganiraju Manyam, Bryan K Kee, David R Fogelman, Arvind Dasari, Kanwal Raghav, Eduardo Vilar, Shanequa Manuel, Imad Shureiqi, Robert A Wolff, Keyur P Patel, Raja Luthra, Kenna Shaw, Cathy Eng, Dipen M Maru, Mark J Routbort, Funda Meric-Bernstam, Edmund S Kopetz
Association of SMAD4 mutation with patient demographics, tumor characteristics, and clinical outcomes in colorectal cancer. PloS one 12 (3) (2017)