Melita Irving

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 21

Top Venues

Ludwig Institute for Cancer Research Lausanne Branch of Immunology

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Ludwig Institute for Cancer Research Lausanne Branch of Immunology Jan 01 2013

Switzerland

Group Leader for T cell Engineering :: Oncology

Publications

Romain Vuillefroy de Silly, Laetitia Troquier, Bili Seijo, Isaac Crespo, Melita Irving
Acidity suppresses CD8 + T-cell function by perturbing IL-2, mTORC1, and c-Myc signaling. The EMBO journal (2024)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, Sergio A Quezada
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology 24 (5) (2023)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, Sergio A Quezada
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology 24 (5) (2023)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, Sergio A Quezada
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology (2023)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, Sergio A Quezada
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology 24 (5) (2023)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, Sergio A Quezada
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology 24 (5) (2023)
Laure Tillé, Daniela Cropp, Mélanie Charmoy, Patrick Reichenbach, Massimo Andreatta, Tania Wyss Lozano, Gabrielle Bodley, Isaac Crespo, Sina Nassiri, Joao Lourenco, Marine M Leblond, Cristina López-Rodríguez, Daniel E Speiser, Sergio A Quezada, Melita Irving, Santiago J Carmona, Werner Held, Grégory Verdeil
Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8 + T cell exhaustion. Nature immunology (2023)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, Sergio A Quezada
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology 24 (5) (2023)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, Sergio A Quezada
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology (2023)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, Sergio A Quezada
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology (2023)
Patrick Reichenbach, Greta Maria Paola Giordano Attianese, Khaoula Ouchen, Elisabetta Cribioli, Melanie Triboulet, Sarah Ash, Margaux Saillard, Romain Vuillefroy de Silly, Sergio A Quezada, Melita Irving
A lentiviral vector for the production of T cells with an inducible transgene and a constitutively expressed tumour-targeting receptor. Nature biomedical engineering (2023)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, Sergio A Quezada
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology (2023)
Greta Maria Paola Giordano Attianese, Sarah Ash, Melita Irving
Coengineering specificity, safety, and function into T cells for cancer immunotherapy. Immunological reviews (2023)
Melita Irving, Yaquelin Ortiz-Miranda, Sergio A Quezada
IL-2 engineered MSCs rescue T cells in tumours. Nature cell biology 24 (12) (2022)
Ute F Röhrig, Somi Reddy Majjigapu, Pierre Vogel, Aline Reynaud, Florence Pojer, Nahzli Dilek, Patrick Reichenbach, Kelly Ascenção, Melita Irving, Sergio A Quezada, Olivier Michielin, Vincent Zoete
Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Melita Irving, Yaquelin Ortiz-Miranda, Sergio A Quezada
IL-2 engineered MSCs rescue T cells in tumours. Nature cell biology 24 (12) (2022)
Melita Irving, Yaquelin Ortiz-Miranda, Sergio A Quezada
IL-2 engineered MSCs rescue T cells in tumours. Nature cell biology 24 (12) (2022)
Evripidis Lanitis, Paris Kosti, Catherine Ronet, Elisabetta Cribioli, Giorgia Rota, Aodrenn Spill, Patrick Reichenbach, Vincent Zoete, Denarda Dangaj Laniti, George Coukos, Melita Irving
VEGFR-2 redirected CAR-T cells are functionally impaired by soluble VEGF-A competition for receptor binding. Journal for immunotherapy of cancer 9 (8) (2022)
Fernanda G Herrera, Catherine Ronet, Maria Ochoa de Olza, David Barras, Isaac Crespo, Massimo Andreatta, Jesus Corria-Osorio, Aodrenn Spill, Fabrizio Benedetti, Raphael Genolet, Angela Orcurto, Martina Imbimbo, Eleonora Ghisoni, Blanca Navarro Rodrigo, Dominik R Berthold, Apostolos Sarivalasis, Khalil Zaman, Rafael Duran, Clarisse Dromain, John O Prior, Niklaus Schaefer, Jean Bourhis, Georgia Dimopoulou, Zoi Tsourti, Marius Messemaker, Thomas Smith, Sarah E Warren, Periklis Foukas, Sylvie Rusakiewicz, Mikael J Pittet, Stefan Zimmermann, Christine Sempoux, Urania Dafni, Alexandre Harari, Lana Elias Kandalaft, Santiago J Carmona, Denarda Dangaj Laniti, Melita Irving, George Coukos
Low Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy. Cancer discovery (2021)
Marion Arnaud, Johanna Chiffelle, Raphael Genolet, Blanca Navarro Rodrigo, Marta A S Perez, Florian Huber, Morgane Magnin, Tu Nguyen-Ngoc, Philippe Guillaume, Petra Baumgaertner, Chloe Chong, Brian J Stevenson, David Gfeller, Melita Irving, Daniel E Speiser, Julien Schmidt, Vincent Zoete, Lana Elias Kandalaft, Michal Bassani-Sternberg, Sara Bobisse, Sergio A Quezada, Alexandre Harari
Sensitive identification of neoantigens and cognate TCRs in human solid tumors. Nature biotechnology (2021)
Greta Giordano-Attianese, Pablo Gainza, Elise Gray-Gaillard, Elisabetta Cribioli, Sailan Shui, Seonghoon Kim, Mi-Jeong Kwak, Sabrina Vollers, Angel De Jesus Corria Osorio, Patrick Reichenbach, Jaume Bonet, Byung-Ha Oh, Melita Irving, George Coukos, Bruno E Correia
A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy. Nature biotechnology 38 (4) (2020)

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Publication Activity (10 Years)

Top Topics

Top Venues

Melita Irving