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George Coukos

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 37

Top Venues

Nature immunology

Nature communications

Clinical and translational medicine

Nature cancer

University Hospital of Lausanne

University of Patras School of Medicine (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University Hospital of Lausanne Jan 1o 2013

Switzerland

Director :: Oncology

Education History

University of Patras School of Medicine Jan 1o 1986 - Dec 1o 1990

Greece

PHD :: Department if Obstetrics and Gynecology

Publications

Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, George Coukos
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology 24 (5) (2023)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, George Coukos
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology 24 (5) (2023)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, George Coukos
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology (2023)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, George Coukos
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology 24 (5) (2023)
Anne I Kraemer, Chloe Chong, Florian Huber, HuiSong Pak, Brian J Stevenson, Markus Müller, Justine Michaux, Emma Ricart Altimiras, Sylvie Rusakiewicz, Laia Simó-Riudalbas, Evarist Planet, Maciej Wiznerowicz, Julien Dagher, Didier Trono, George Coukos, Stephanie Tissot, Michal Bassani-Sternberg
The immunopeptidome landscape associated with T cell infiltration, inflammation and immune editing in lung cancer. Nature cancer (2023)
Marion Arnaud, George Coukos, Alexandre Harari
Towards next-generation TIL therapy: TILs enriched in neoepitope-specific T cells. Clinical and translational medicine 13 (1) (2023)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, George Coukos
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology 24 (5) (2023)
Marion Arnaud, George Coukos, Alexandre Harari
Towards next-generation TIL therapy: TILs enriched in neoepitope-specific T cells. Clinical and translational medicine 13 (1) (2023)
Sara Bobisse, Valentina Bianchi, Janos L Tanyi, Apostolos Sarivalasis, Edoardo Missiaglia, Rémy Pétremand, Fabrizio Benedetti, Drew A Torigian, Raphaël Genolet, David Barras, Alexandra Michel, Spyridon A Mastroyannis, Emese Zsiros, Denarda Dangaj Laniti, Zoi Tsourti, Brian J Stevenson, Christian Iseli, Bruce L Levine, Daniel E Speiser, David Gfeller, Michal Bassani-Sternberg, Daniel J Powell, Carl H June, Urania Dafni, Lana Elias Kandalaft, Alexandre Harari, George Coukos
A phase 1 trial of adoptive transfer of vaccine-primed autologous circulating T cells in ovarian cancer. Nature cancer (2023)
Laure Tillé, Daniela Cropp, Mélanie Charmoy, Patrick Reichenbach, Massimo Andreatta, Tania Wyss Lozano, Gabrielle Bodley, Isaac Crespo, Sina Nassiri, Joao Lourenco, Marine M Leblond, Cristina López-Rodríguez, Daniel E Speiser, George Coukos, Melita Irving, Santiago J Carmona, Werner Held, Grégory Verdeil
Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8 + T cell exhaustion. Nature immunology (2023)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, George Coukos
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology 24 (5) (2023)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, George Coukos
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology (2023)
Marion Arnaud, George Coukos, Alexandre Harari
Towards next-generation TIL therapy: TILs enriched in neoepitope-specific T cells. Clinical and translational medicine 13 (1) (2023)
Anne I Kraemer, Chloe Chong, Florian Huber, HuiSong Pak, Brian J Stevenson, Markus Müller, Justine Michaux, Emma Ricart Altimiras, Sylvie Rusakiewicz, Laia Simó-Riudalbas, Evarist Planet, Maciej Wiznerowicz, Julien Dagher, Didier Trono, George Coukos, Stephanie Tissot, Michal Bassani-Sternberg
The immunopeptidome landscape associated with T cell infiltration, inflammation and immune editing in lung cancer. Nature cancer (2023)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, George Coukos
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology (2023)
Patrick Reichenbach, Greta Maria Paola Giordano Attianese, Khaoula Ouchen, Elisabetta Cribioli, Melanie Triboulet, Sarah Ash, Margaux Saillard, Romain Vuillefroy de Silly, George Coukos, Melita Irving
A lentiviral vector for the production of T cells with an inducible transgene and a constitutively expressed tumour-targeting receptor. Nature biomedical engineering (2023)
Jesus Corria-Osorio, Santiago J Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A Luther, Melita Irving, George Coukos
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8 + T cells. Nature immunology (2023)
Julien Schmidt, Johanna Chiffelle, Marta A S Perez, Morgane Magnin, Sara Bobisse, Marion Arnaud, Raphaël Genolet, Julien Cesbron, David Barras, Blanca Navarro Rodrigo, Fabrizio Benedetti, Alexandra Michel, Lise Queiroz, Petra Baumgaertner, Philippe Guillaume, Michael Hebeisen, Olivier Michielin, Tu Nguyen-Ngoc, Florian Huber, Melita Irving, Stéphanie Tissot-Renaud, Brian J Stevenson, Sylvie Rusakiewicz, Denarda Dangaj Laniti, Michal Bassani-Sternberg, Nathalie Rufer, David Gfeller, Lana Elias Kandalaft, Daniel E Speiser, Vincent Zoete, George Coukos, Alexandre Harari
Neoantigen-specific CD8 T cells with high structural avidity preferentially reside in and eliminate tumors. Nature communications 14 (1) (2023)
Marion Arnaud, George Coukos, Alexandre Harari
Towards next-generation TIL therapy: TILs enriched in neoepitope-specific T cells. Clinical and translational medicine 13 (1) (2023)
Lana Elias Kandalaft, Denarda Dangaj Laniti, George Coukos
Immunobiology of high-grade serous ovarian cancer: lessons for clinical translation. Nature reviews. Cancer 22 (11) (2022)
Melita Irving, Yaquelin Ortiz-Miranda, George Coukos
IL-2 engineered MSCs rescue T cells in tumours. Nature cell biology 24 (12) (2022)
Ute F Röhrig, Somi Reddy Majjigapu, Pierre Vogel, Aline Reynaud, Florence Pojer, Nahzli Dilek, Patrick Reichenbach, Kelly Ascenção, Melita Irving, George Coukos, Olivier Michielin, Vincent Zoete
Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Melita Irving, Yaquelin Ortiz-Miranda, George Coukos
IL-2 engineered MSCs rescue T cells in tumours. Nature cell biology 24 (12) (2022)
Melita Irving, Yaquelin Ortiz-Miranda, George Coukos
IL-2 engineered MSCs rescue T cells in tumours. Nature cell biology 24 (12) (2022)
Amélie Cachot, Mariia Bilous, Yen-Cheng Liu, Xiaokang Li, Margaux Saillard, Mara Cenerenti, Georg Alexander Rockinger, Tania Wyss Lozano, Philippe Guillaume, Julien Schmidt, Raphaël Genolet, Giuseppe Ercolano, Maria Pia Protti, Walter Reith, Kalliopi Ioannidou, Laurence de Leval, Joseph A Trapani, George Coukos, Alexandre Harari, Daniel E Speiser, Alexander Mathis, David Gfeller, Hatice Altug, Pedro Romero, Camilla Jandus
Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer. Science advances 7 (9) (2021)
Hakimeh Ebrahimi-Nik, Marmar Moussa, Ryan P Englander, Summit Singhaviranon, Justine Michaux, HuiSong Pak, Hiroko Miyadera, William L Corwin, Grant L J Keller, Adam T Hagymasi, Tatiana V Shcheglova, George Coukos, Brian M Baker, Ion I Măndoiu, Michal Bassani-Sternberg, Pramod K Srivastava
Reversion analysis reveals the in vivo immunogenicity of a poorly MHC I-binding cancer neoepitope. Nature communications 12 (1) (2021)
Chloe Chong, George Coukos, Michal Bassani-Sternberg
Identification of tumor antigens with immunopeptidomics. Nature biotechnology (2021)
Marion Arnaud, Johanna Chiffelle, Raphael Genolet, Blanca Navarro Rodrigo, Marta A S Perez, Florian Huber, Morgane Magnin, Tu Nguyen-Ngoc, Philippe Guillaume, Petra Baumgaertner, Chloe Chong, Brian J Stevenson, David Gfeller, Melita Irving, Daniel E Speiser, Julien Schmidt, Vincent Zoete, Lana Elias Kandalaft, Michal Bassani-Sternberg, Sara Bobisse, George Coukos, Alexandre Harari
Sensitive identification of neoantigens and cognate TCRs in human solid tumors. Nature biotechnology (2021)
Massimo Andreatta, Jesus Corria-Osorio, Sören Müller, Rafael Cubas, George Coukos, Santiago J Carmona
Interpretation of T cell states from single-cell transcriptomics data using reference atlases. Nature communications 12 (1) (2021)
Matthieu Dietz, Christel-Hermann Kamani, Emmanuel Deshayes, Vincent Dunet, Periklis Mitsakis, George Coukos, Marie Nicod-Lalonde, Niklaus Schaefer, John O Prior
Imaging angiogenesis in atherosclerosis in large arteries with 68Ga-NODAGA-RGD PET/CT: relationship with clinical atherosclerotic cardiovascular disease. EJNMMI research 11 (1) (2021)
Chloe Chong, Markus Müller, HuiSong Pak, Dermot Harnett, Florian Huber, Delphine Grun, Marion Leleu, Aymeric Auger, Marion Arnaud, Brian J Stevenson, Justine Michaux, Ilija Bilic, Antje Hirsekorn, Lorenzo Calviello, Laia Simó-Riudalbas, Evarist Planet, Jan Lubiński, Marta Bryśkiewicz, Maciej Wiznerowicz, Ioannis Xenarios, Lin Zhang, Didier Trono, Alexandre Harari, Uwe Ohler, George Coukos, Michal Bassani-Sternberg
Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes. Nature communications 11 (1) (2020)
Nathalie Brandenberg, Sylke Hoehnel, Fabien Kuttler, Krisztian Homicsko, Camilla Ceroni, Till Ringel, Nikolce Gjorevski, Gerald Schwank, George Coukos, Gerardo Turcatti, Matthias P Lutolf
High-throughput automated organoid culture via stem-cell aggregation in microcavity arrays. Nature biomedical engineering 4 (9) (2020)
Yi-Ru Yu, Hana Imrichova, Haiping Wang, Tung Chao, Zhengtao Xiao, Min Gao, Marcela Rincon-Restrepo, Fabien Franco, Raphael Genolet, Wan-Chen Cheng, Camilla Jandus, George Coukos, Yi-Fan Jiang, Jason W Locasale, Alfred Zippelius, Pu-Ste Liu, Li Tang, Christoph Bock, Nicola Vannini, Ping-Chih Ho
Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion. Nature immunology 21 (12) (2020)
Natalie J Neubert, Martina Schmittnaegel, Natacha Bordry, Sina Nassiri, Noémie Wald, Christophe Martignier, Laure Tillé, Krisztian Homicsko, William E Damsky, Hélène Maby-El Hajjami, Irina Klaman, Esther Danenberg, Kalliopi Ioannidou, Lana Elias Kandalaft, George Coukos, Sabine Hoves, Carola H Ries, Silvia A Fuertes Marraco, Periklis G Foukas, Michele De Palma, Daniel E Speiser
T cell-induced CSF1 promotes melanoma resistance to PD1 blockade. Science translational medicine 10 (436) (2019)
Janos L Tanyi, Sara Bobisse, Eran Ophir, Sandra Tuyaerts, Annalisa Roberti, Raphaël Genolet, Petra Baumgartner, Brian J Stevenson, Christian Iseli, Denarda Dangaj, Brian J Czerniecki, Aikaterini Semilietof, Julien Racle, Alexandra Michel, Ioannis Xenarios, Cheryl Chiang, Dimitri S Monos, Drew A Torigian, Harvey L Nisenbaum, Olivier Michielin, Carl H June, Bruce L Levine, Daniel J Powell, David Gfeller, Rosemarie Mick, Urania Dafni, Vincent Zoete, Alexandre Harari, George Coukos, Lana Elias Kandalaft
Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer. Science translational medicine 10 (436) (2019)
Michele Maio, George Coukos, Soldano Ferrone, Bernard A Fox, Wolf Herman Fridman, Patrick L Garcia, Michael Lahn, Olivier Provendier, Vincenzo Russo, Dominik Rüttinger, Aiman Shalabi, Zlatko Trajanoski, Jean Viallet, Jedd D Wolchok, Ramy Ibrahim
Addressing current challenges and future directions in immuno-oncology: expert perspectives from the 2017 NIBIT Foundation Think Tank, Siena, Italy. Cancer immunology, immunotherapy : CII 68 (1) (2018)
Riccardo Turrini, Angélique Pabois, Ioannis Xenarios, George Coukos, Jean-François Delaloye, Marie-Agnès Doucey
TIE-2 expressing monocytes in human cancers. Oncoimmunology 6 (4) (2017)

George Coukos.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

George Coukos