Mikael Akke (M Akke)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 53

Top Venues

Biochemistry

The journal of physical chemistry. B

Journal of the American Chemical Society

International journal of molecular sciences

Lund University (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

Lund University Sep 01 1987 - May 12 1993

Sweden

PHD :: Department of Physical Chemistry 2

Lund University Sep 01 1982 - Aug 31 1987

Sweden

MSC :: Lund Institute of Technology, Chemical Engineering

Publications

Olof Stenström, Carl Diehl, Kristofer Modig, Mikael Akke
Ligand-induced protein transition state stabilization switches the binding pathway from conformational selection to induced fit. Proceedings of the National Academy of Sciences of the United States of America 121 (14) (2024)
Olof Stenström, Carl Diehl, Kristofer Modig, Mikael Akke
Ligand-induced protein transition state stabilization switches the binding pathway from conformational selection to induced fit. Proceedings of the National Academy of Sciences of the United States of America 121 (14) (2024)
Olof Stenström, Carl Diehl, Kristofer Modig, Mikael Akke
Ligand-induced protein transition state stabilization switches the binding pathway from conformational selection to induced fit. Proceedings of the National Academy of Sciences of the United States of America 121 (14) (2024)
Olof Stenström, Carl Diehl, Kristofer Modig, Mikael Akke
Ligand-induced protein transition state stabilization switches the binding pathway from conformational selection to induced fit. Proceedings of the National Academy of Sciences of the United States of America 121 (14) (2024)
Roza Kalabekova, Caitlin M Quinn, Kumar Tekwani Movellan, Angela M Gronenborn, Mikael Akke, Tatyana Polenova
19 F Fast Magic-Angle Spinning NMR Spectroscopy on Microcrystalline Complexes of Fluorinated Ligands and the Carbohydrate Recognition Domain of Galectin-3. Biochemistry (2024)
Heiner N Raum, Kristofer Modig, Mikael Akke, Ulrich Weininger
Proton Transfer Kinetics in Histidine Side Chains Determined by pH-Dependent Multi-Nuclear NMR Relaxation. Journal of the American Chemical Society 146 (32) (2024)
Heiner N Raum, Kristofer Modig, Mikael Akke, Ulrich Weininger
Proton Transfer Kinetics in Histidine Side Chains Determined by pH-Dependent Multi-Nuclear NMR Relaxation. Journal of the American Chemical Society 146 (32) (2024)
Roza Kalabekova, Caitlin M Quinn, Kumar Tekwani Movellan, Angela M Gronenborn, Mikael Akke, Tatyana Polenova
19 F Fast Magic-Angle Spinning NMR Spectroscopy on Microcrystalline Complexes of Fluorinated Ligands and the Carbohydrate Recognition Domain of Galectin-3. Biochemistry 63 (17) (2024)
Heiner N Raum, Kristofer Modig, Mikael Akke, Ulrich Weininger
Proton Transfer Kinetics in Histidine Side Chains Determined by pH-Dependent Multi-Nuclear NMR Relaxation. Journal of the American Chemical Society (2024)
Heiner N Raum, Kristofer Modig, Mikael Akke, Ulrich Weininger
Proton Transfer Kinetics in Histidine Side Chains Determined by pH-Dependent Multi-Nuclear NMR Relaxation. Journal of the American Chemical Society 146 (32) (2024)
Simon Christensen, Olof Stenström, Mikael Akke, Leif Bülow
Conformational Dynamics of Phytoglobin BvPgb1.2 from Beta vulgaris ssp. vulgaris . International journal of molecular sciences 24 (4) (2023)
Mikael Akke, Ulrich Weininger
NMR Studies of Aromatic Ring Flips to Probe Conformational Fluctuations in Proteins. The journal of physical chemistry. B (2023)
Simon Christensen, Olof Stenström, Mikael Akke, Leif Bülow
Conformational Dynamics of Phytoglobin BvPgb1.2 from Beta vulgaris ssp. vulgaris . International journal of molecular sciences 24 (4) (2023)
Mikael Akke, Ulrich Weininger
NMR Studies of Aromatic Ring Flips to Probe Conformational Fluctuations in Proteins. The journal of physical chemistry. B 127 (3) (2023)
Mikael Akke, Ulrich Weininger
NMR Studies of Aromatic Ring Flips to Probe Conformational Fluctuations in Proteins. The journal of physical chemistry. B 127 (3) (2023)
Mikael Akke, Ulrich Weininger
NMR Studies of Aromatic Ring Flips to Probe Conformational Fluctuations in Proteins. The journal of physical chemistry. B 127 (3) (2023)
Simon Christensen, Olof Stenström, Mikael Akke, Leif Bülow
Conformational Dynamics of Phytoglobin BvPgb1.2 from Beta vulgaris ssp. vulgaris . International journal of molecular sciences 24 (4) (2023)
Mikael Akke, Ulrich Weininger
NMR Studies of Aromatic Ring Flips to Probe Conformational Fluctuations in Proteins. The journal of physical chemistry. B 127 (3) (2023)
Simon Christensen, Olof Stenström, Mikael Akke, Leif Bülow
Conformational Dynamics of Phytoglobin BvPgb1.2 from Beta vulgaris ssp. vulgaris . International journal of molecular sciences 24 (4) (2023)
Simon Christensen, Olof Stenström, Mikael Akke, Leif Bülow
Conformational Dynamics of Phytoglobin BvPgb1.2 from Beta vulgaris ssp. vulgaris . International journal of molecular sciences 24 (4) (2023)
Mikael Akke, Ulrich Weininger
NMR Studies of Aromatic Ring Flips to Probe Conformational Fluctuations in Proteins. The journal of physical chemistry. B 127 (3) (2023)
Simon Christensen, Olof Stenström, Mikael Akke, Leif Bülow
Conformational Dynamics of Phytoglobin BvPgb1.2 from Beta vulgaris ssp. vulgaris . International journal of molecular sciences 24 (4) (2023)
Sven Wernersson, Simon Birgersson, Mikael Akke
Cosolvent Dimethyl Sulfoxide Influences Protein-Ligand Binding Kinetics via Solvent Viscosity Effects: Revealing the Success Rate of Complex Formation Following Diffusive Protein-Ligand Encounter. Biochemistry 62 (1) (2022)
Sven Wernersson, Simon Birgersson, Mikael Akke
Cosolvent Dimethyl Sulfoxide Influences Protein-Ligand Binding Kinetics via Solvent Viscosity Effects: Revealing the Success Rate of Complex Formation Following Diffusive Protein-Ligand Encounter. Biochemistry 62 (1) (2022)
Sven Wernersson, Simon Birgersson, Mikael Akke
Cosolvent Dimethyl Sulfoxide Influences Protein-Ligand Binding Kinetics via Solvent Viscosity Effects: Revealing the Success Rate of Complex Formation Following Diffusive Protein-Ligand Encounter. Biochemistry 62 (1) (2022)
Sven Wernersson, Simon Birgersson, Mikael Akke
Cosolvent Dimethyl Sulfoxide Influences Protein-Ligand Binding Kinetics via Solvent Viscosity Effects: Revealing the Success Rate of Complex Formation Following Diffusive Protein-Ligand Encounter. Biochemistry 62 (1) (2022)
Sven Wernersson, Simon Birgersson, Mikael Akke
Cosolvent Dimethyl Sulfoxide Influences Protein-Ligand Binding Kinetics via Solvent Viscosity Effects: Revealing the Success Rate of Complex Formation Following Diffusive Protein-Ligand Encounter. Biochemistry 62 (1) (2022)
Sven Wernersson, Simon Birgersson, Mikael Akke
Cosolvent Dimethyl Sulfoxide Influences Protein-Ligand Binding Kinetics via Solvent Viscosity Effects: Revealing the Success Rate of Complex Formation Following Diffusive Protein-Ligand Encounter. Biochemistry (2022)
Sven Wernersson, Romel Bobby, Liz Flavell, Alexander G Milbradt, Geoffrey A Holdgate, Kevin J Embrey, Mikael Akke
Bromodomain Interactions with Acetylated Histone 4 Peptides in the BRD4 Tandem Domain: Effects on Domain Dynamics and Internal Flexibility. Biochemistry 61 (21) (2022)
Matthias Dreydoppel, Mikael Akke, Ulrich Weininger
Characterizing Fast Conformational Exchange of Aromatic Rings Using Residual Dipolar Couplings: Distinguishing Jumplike Flips from Other Exchange Mechanisms. The journal of physical chemistry. B 126 (40) (2022)
Matthias Dreydoppel, Britta Dorn, Kristofer Modig, Mikael Akke, Ulrich Weininger
Transition-State Compressibility and Activation Volume of Transient Protein Conformational Fluctuations. JACS Au 1 (6) (2021)
Raminta Venskutonytė, Ara Koh, Olof Stenström, Muhammad Tanweer Khan, Annika Lundqvist, Mikael Akke, Fredrik Bäckhed, Karin Lindkvist-Petersson
Structural characterization of the microbial enzyme urocanate reductase mediating imidazole propionate production. Nature communications 12 (1) (2021)
Johan Wallerstein, Vilhelm Ekberg, Majda Misini Ignjatović, Rohit Kumar, Octav Caldararu, Kristoffer Peterson, Sven Wernersson, Ulrika Brath, Hakon Leffler, Esko Oksanen, Derek T Logan, Ulf J Nilsson, Ulf Ryde, Mikael Akke
Entropy-Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C. JACS Au 1 (4) (2021)
Olof Stenström, Carl Diehl, Kristofer Modig, Ulf J Nilsson, Mikael Akke
Mapping the energy landscape of protein-ligand binding via linear free energy relationships determined by protein NMR relaxation dispersion. RSC chemical biology 2 (1) (2020)
Jodi Kraus, Rupal Gupta, Manman Lu, Angela M Gronenborn, Mikael Akke, Tatyana Polenova
Accurate Backbone 13 C and 15 N Chemical Shift Tensors in Galectin-3 Determined by MAS NMR and QM/MM: Details of Structure and Environment Matter. Chemphyschem : a European journal of chemical physics and physical chemistry 21 (13) (2020)
C Köhler, Göran Carlström, A Gunnarsson, Ulrich Weininger, Stefan Tångefjord, V Ullah, M Lepistö, U Karlsson, T Papavoine, Karl Edman, Mikael Akke
Dynamic allosteric communication pathway directing differential activation of the glucocorticoid receptor. Science advances 6 (29) (2020)
Mattias Törnquist, Risto Cukalevski, Ulrich Weininger, Georg Meisl, Tuomas P J Knowles, Thom Leiding, Anders Malmendal, Mikael Akke, Sara Linse
Ultrastructural evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils. Proceedings of the National Academy of Sciences of the United States of America 117 (21) (2020)
Ulrich Weininger, Kristofer Modig, Hiroaki Ishida, Hans J Vogel, Mikael Akke
Rotamer Jumps, Proton Exchange, and Amine Inversion Dynamics of Dimethylated Lysine Residues in Proteins Resolved by pH-Dependent 1H and 13C NMR Relaxation Dispersion. The journal of physical chemistry. B 123 (46) (2019)
Anna Bille, Kristine Steen Jensen, Sandipan Mohanty, Mikael Akke, Anders Irbäck
Stability and Local Unfolding of SOD1 in the Presence of Protein Crowders. The journal of physical chemistry. B 123 (9) (2019)
Göran Carlström, Filip Elvander, Johan Swärd, Andreas Jakobsson, Mikael Akke
Rapid NMR Relaxation Measurements Using Optimal Nonuniform Sampling of Multidimensional Accordion Data Analyzed by a Sparse Reconstruction Method. The journal of physical chemistry. A 123 (27) (2019)
Sven Wernersson, Viktoria Bågenholm, Cecilia Persson, Santosh Kumar Upadhyay, Henrik Stålbrand, Mikael Akke
Backbone 1H, 13C, and 15N resonance assignments of BoMan26A, a β-mannanase of the glycoside hydrolase family 26 from the human gut bacterium Bacteroides ovatus. Biomolecular NMR assignments 13 (1) (2019)
Kristine Steen Jensen, Sara Linse, Mathias Nilsson, Mikael Akke, Anders Malmendal
Revealing Well-Defined Soluble States during Amyloid Fibril Formation by Multilinear Analysis of NMR Diffusion Data. Journal of the American Chemical Society 141 (47) (2019)
Maria Luisa Verteramo, Olof Stenström, Majda Misini Ignjatović, Octav Caldararu, Martin A Olsson, Francesco Manzoni, Hakon Leffler, Esko Oksanen, Derek T Logan, Ulf J Nilsson, Ulf Ryde, Mikael Akke
Interplay between Conformational Entropy and Solvation Entropy in Protein-Ligand Binding. Journal of the American Chemical Society 141 (5) (2019)
Johan Wallerstein, Mikael Akke
Minute Additions of DMSO Affect Protein Dynamics Measurements by NMR Relaxation Experiments through Significant Changes in Solvent Viscosity. Chemphyschem : a European journal of chemical physics and physical chemistry 20 (2) (2018)
Gleb Solomentsev, Carl Diehl, Mikael Akke
Conformational Entropy of FK506 Binding to FKBP12 Determined by Nuclear Magnetic Resonance Relaxation and Molecular Dynamics Simulations. Biochemistry 57 (9) (2018)
Christian Köhler, Göran Carlström, Stefan Tångefjord, Tineke Papavoine, Matti Lepistö, Karl Edman, Mikael Akke
Backbone 1H, 13C, and 15N resonance assignments of the ligand binding domain of the human wildtype glucocorticoid receptor and the F602S mutant variant. Biomolecular NMR assignments 12 (2) (2018)
Francesco Manzoni, Johan Wallerstein, Tobias E Schrader, Andreas Ostermann, Leighton Coates, Mikael Akke, Matthew P Blakeley, Esko Oksanen, Derek T Logan
Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design. Journal of medicinal chemistry 61 (10) (2018)
Kristoffer Peterson, Rohit Kumar, Olof Stenström, Priya Verma, Prashant R Verma, Maria Håkansson, Barbro Kahl-Knutsson, Fredrik Zetterberg, Hakon Leffler, Mikael Akke, Derek T Logan, Ulf J Nilsson
Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity. Journal of medicinal chemistry 61 (3) (2018)
Jodi Kraus, Rupal Gupta, Jenna Yehl, Manman Lu, David A Case, Angela M Gronenborn, Mikael Akke, Tatyana Polenova
Chemical Shifts of the Carbohydrate Binding Domain of Galectin-3 from Magic Angle Spinning NMR and Hybrid Quantum Mechanics/Molecular Mechanics Calculations. The journal of physical chemistry. B 122 (11) (2018)
Cecilia Månsson, Remco T P van Cruchten, Ulrich Weininger, Xiaoting Yang, Risto Cukalevski, Paolo Arosio, Christopher M Dobson, Tuomas P J Knowles, Mikael Akke, Sara Linse, Cecilia Emanuelsson
Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of Aβ42 Amyloid Fibril Formation. Biochemistry 57 (32) (2018)
Clare-Louise Towse, Mikael Akke, Valerie Daggett
The Dynameomics Entropy Dictionary: A Large-Scale Assessment of Conformational Entropy across Protein Fold Space. The journal of physical chemistry. B 121 (16) (2017)
M Ashhar I Khan, Michal Respondek, Sven Kjellström, Shashank Deep, Sara Linse, Mikael Akke
Cu/Zn Superoxide Dismutase Forms Amyloid Fibrils under Near-Physiological Quiescent Conditions: The Roles of Disulfide Bonds and Effects of Denaturant. ACS chemical neuroscience 8 (9) (2017)
Ulrich Weininger, Kristofer Modig, Anne-Juliane Geitner, Philipp A M Schmidpeter, Johanna R Koch, Mikael Akke
Dynamics of Aromatic Side Chains in the Active Site of FKBP12. Biochemistry 56 (1) (2016)

Mikael Akke.css-eqlu8i{font-size:small;padding-left:4px;} (M Akke)

Publication Activity (10 Years)

Top Topics

Top Venues

Mikael Akke (M Akke)