Mudra Hegde

ORCID

Publication Activity (10 Years)

Years Active: 2018-2022
Publications (10 Years): 9

Top Venues

Nature communications

Nature biotechnology

Research square

Nature genetics

Broad Institute

Northeastern University (MSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Broad Institute Jun 03 2013

United States

Senior Computational Biologist :: Genetic Perturbation Platform

Education History

Northeastern University Sep 05 2011 - May 03 2013

United States

MSC :: Bioinformatics

Publications

Annabel K Sangree, Audrey L Griffith, Zsofia M Szegletes, Priyanka Roy, Peter C DeWeirdt, Mudra Hegde, Abby V McGee, Ruth E Hanna, John G Doench
Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2. Nature communications 13 (1) (2022)
Peter C DeWeirdt, Abby V McGee, Fengyi Zheng, Ifunanya Nwolah, Mudra Hegde, John G Doench
Accounting for small variations in the tracrRNA sequence improves sgRNA activity predictions for CRISPR screening. Nature communications 13 (1) (2022)
Antoine Rebendenne, Priyanka Roy, Boris Bonaventure, Ana Luiza Chaves Valadão, Lowiese Desmarets, Mary Arnaud-Arnould, Yves Rouillé, Marine Tauziet, Donatella Giovannini, Jawida Touhami, Yenarae Lee, Peter DeWeirdt, Mudra Hegde, Serge Urbach, Khadija El Koulali, Francisco Garcia de Gracia, Joe McKellar, Jean Dubuisson, Mélanie Wencker, Sandrine Belouzard, Olivier Moncorgé, John G Doench, Caroline Goujon
Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal HCoVs. Nature genetics 54 (8) (2022)
Caroline Goujon, Antoine Rebendenne, Priyanka Roy, Boris Bonaventure, Ana Chaves Valadao, Lowiese Desmarets, Yves Rouillé, Marine Tauziet, Mary Arnaud-Arnould, Donatella Giovannini, Yenarae Lee, Peter DeWeirdt, Mudra Hegde, Francisco Garcia de Gracia, Joe McKellar, Mélanie Wencker, Jean Dubuisson, Sandrine Belouzard, Olivier Moncorgé, John G Doench
Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal HCoVs. Research square (2021)
Antoine Rebendenne, Priyanka Roy, Boris Bonaventure, Ana Luiza Chaves Valadão, Lowiese Desmarets, Yves Rouillé, Marine Tauziet, Mary Arnaud-Arnould, Donatella Giovannini, Yenarae Lee, Peter DeWeirdt, Mudra Hegde, Francisco Garcia de Gracia, Joe McKellar, Mélanie Wencker, Jean Dubuisson, Sandrine Belouzard, Olivier Moncorgé, John G Doench, Caroline Goujon
Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal coronaviruses. bioRxiv : the preprint server for biology (2021)
Peter C DeWeirdt, Annabel K Sangree, Ruth E Hanna, Kendall R Sanson, Mudra Hegde, Christine Strand, Nicole S Persky, John G Doench
Genetic screens in isogenic mammalian cell lines without single cell cloning. Nature communications 11 (1) (2020)
Peter C DeWeirdt, Kendall R Sanson, Annabel K Sangree, Mudra Hegde, Ruth E Hanna, Marissa N Feeley, Audrey L Griffith, Teng Teng, Samantha M Borys, Christine Strand, J Keith Joung, Benjamin P Kleinstiver, Xuewen Pan, Alan Huang, John G Doench
Optimization of AsCas12a for combinatorial genetic screens in human cells. Nature biotechnology 39 (1) (2020)
Kendall R Sanson, Ruth E Hanna, Mudra Hegde, Katherine F Donovan, Christine Strand, Meagan E Sullender, Emma W Vaimberg, Amy Goodale, David E Root, Frederica Piccioni, John G Doench
Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities. Nature communications 9 (1) (2018)
Mudra Hegde, Christine Strand, Ruth E Hanna, John G Doench
Uncoupling of sgRNAs from their associated barcodes during PCR amplification of combinatorial CRISPR screens. PloS one 13 (5) (2018)

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Publication Activity (10 Years)

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Mudra Hegde