Nathaniel W Snyder (Nathaniel Snyder, N W Snyder)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 49

Top Venues

bioRxiv : the preprint server for biology

Cancer research communications

Research square

Science advances

Temple University Lewis Katz School of Medicine

University of Pennsylvania (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Temple University Lewis Katz School of Medicine Jan 01 2020

United States

Associate Professor :: Center for Metabolic Disease Research, Department of Micrbiology and Immunology

Drexel University - Dec 31 2019

United States

Assistant Professor :: AJ Drexel Autism Institute

Education History

University of Pennsylvania Jul 01 2009 - Dec 21 2013

United States

PHD :: Pharmacology

Publications

Jonathan Chernoff, Konstantin Budagyan, Alexa Cannon, Adam Chatoff, Nathaniel W Snyder, Alison N Kurimchak, James Duncan
KRAS mutation-selective requirement for ACSS2 in colorectal adenoma formation. Research square (2024)
Naveen Kumar Tangudu, Raquel Buj, Hui Wang, Jiefei Wang, Aidan R Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Baixue Yang, Adam Chatoff, Claudia V Crispim, Peter Sajjakulnukit, Maureen A Lyons, Kristine L Cooper, Nadine Hempel, Costas Andreas Lyssiotis, Uma R Chandran, Nathaniel W Snyder, Katherine Marie Aird
De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression. Cancer research communications (2024)
Apoorva Uboveja, Zhentai Huang, Raquel Buj, Amandine Amalric, Hui Wang, Naveen Kumar Tangudu, Aidan R Cole, Emily Megill, Daniel Kantner, Adam Chatoff, Hafsah Ahmad, Mariola M Marcinkiewicz, Julie A Disharoon, Sarah Graff, Erika S Dahl, Nadine Hempel, Wayne Stallaert, Simone Sidoli, Benjamin G Bitler, David T Long, Nathaniel W Snyder, Katherine Marie Aird
αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation. bioRxiv : the preprint server for biology (2024)
Naveen Kumar Tangudu, Raquel Buj, Hui Wang, Jiefei Wang, Aidan R Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Baixue Yang, Adam Chatoff, Claudia V Crispim, Peter Sajjakulnukit, Maureen A Lyons, Kristine L Cooper, Nadine Hempel, Costas Andreas Lyssiotis, Uma R Chandran, Nathaniel W Snyder, Katherine Marie Aird
De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression. Cancer research communications 4 (5) (2024)
Jonathan Chernoff, Konstantin Budagyan, Alexa Cannon, Adam Chatoff, Nathaniel W Snyder, Alison N Kurimchak, James Duncan
KRAS mutation-selective requirement for ACSS2 in colorectal adenoma formation. Research square (2024)
Naveen Kumar Tangudu, Raquel Buj, Hui Wang, Jiefei Wang, Aidan R Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Baixue Yang, Adam Chatoff, Claudia V Crispim, Peter Sajjakulnukit, Maureen A Lyons, Kristine L Cooper, Nadine Hempel, Costas Andreas Lyssiotis, Uma R Chandran, Nathaniel W Snyder, Katherine Marie Aird
De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression. Cancer research communications 4 (5) (2024)
Nicholas Forelli, Deborah Eaton, Jiten Patel, Caitlyn E Bowman, Ryo Kawakami, Ivan A Kuznetsov, Kristina Li, Claire Brady, Kenneth Bedi, Yijun Yang, Kaustubh Koya, Emily Megill, Daniel S Kanter, Louis G Smith, Gregory R Bowman, Nathaniel W Snyder, Jonathan Edwards, Kenneth Margulies, Zoltan Arany
SGLT2 inhibitors activate pantothenate kinase in the human heart. bioRxiv : the preprint server for biology (2024)
Apoorva Uboveja, Zhentai Huang, Raquel Buj, Amandine Amalric, Hui Wang, Naveen Kumar Tangudu, Aidan R Cole, Emily Megill, Daniel Kantner, Adam Chatoff, Hafsah Ahmad, Mariola M Marcinkiewicz, Julie A Disharoon, Sarah Graff, Erika S Dahl, Nadine Hempel, Wayne Stallaert, Simone Sidoli, Benjamin G Bitler, David T Long, Nathaniel W Snyder, Katherine Marie Aird
αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation. bioRxiv : the preprint server for biology (2024)
Allison C Sharrow, Emily Megill, Amanda J Chen, Afifa Farooqi, Stacy McGonigal, Nadine Hempel, Nathaniel W Snyder, Ronald J Buckanovich, Katherine M Aird
Acetate drives ovarian cancer quiescence via ACSS2-mediated acetyl-CoA production. bioRxiv : the preprint server for biology (2024)
Naveen Kumar Tangudu, Raquel Buj, Hui Wang, Jiefei Wang, Aidan R Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Baixue Yang, Adam Chatoff, Claudia V Crispim, Peter Sajjakulnukit, Maureen A Lyons, Kristine L Cooper, Nadine Hempel, Costas Andreas Lyssiotis, Uma R Chandran, Nathaniel W Snyder, Katherine Marie Aird
De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression. Cancer research communications 4 (5) (2024)
Nicholas Forelli, Deborah Eaton, Jiten Patel, Caitlyn E Bowman, Ryo Kawakami, Ivan A Kuznetsov, Kristina Li, Claire Brady, Kenneth Bedi, Yijun Yang, Kaustubh Koya, Emily Megill, Daniel S Kanter, Louis G Smith, Gregory R Bowman, Nathaniel W Snyder, Jonathan Edwards, Kenneth Margulies, Zoltan Arany
SGLT2 inhibitors activate pantothenate kinase in the human heart. bioRxiv : the preprint server for biology (2024)
Di Zhang, Jinjun Gao, Zhijun Zhu, Qianying Mao, Zhiqiang Xu, Pankaj K Singh, Cornelius C Rimayi, Carlos Moreno-Yruela, Shuling Xu, Gongyu Li, Yi-Cheng Sin, Yue Chen, Christian A Olsen, Nathaniel W Snyder, Lunzhi Dai, Lingjun Li, Yingming Zhao
Lysine L-lactylation is the dominant lactylation isomer induced by glycolysis. Nature chemical biology (2024)
Bakir Valentić, Andre Kelly, Alexander A Shestov, Zhiyang Gan, Feng Shen, Adam Chatoff, Alison Jaccard, Claudia V Crispim, John Scholler, Simon Heeke, Nathaniel W Snyder, Saba Ghassemi, Nicholas Jones, Saar I Gill, Roderick O'Connor
The Glucose Transporter 5 Enhances CAR-T Cell Metabolic Function and Anti-tumour Durability. Research square (2024)
Naveen Kumar Tangudu, Raquel Buj, Hui Wang, Jiefei Wang, Aidan R Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Baixue Yang, Adam Chatoff, Claudia V Crispim, Peter Sajjakulnukit, Maureen A Lyons, Kristine L Cooper, Nadine Hempel, Costas Andreas Lyssiotis, Uma R Chandran, Nathaniel W Snyder, Katherine Marie Aird
De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression. Cancer research communications (2024)
Konstantin Budyagan, Alexa C Cannon, Adam Chatoff, Nathaniel W Snyder, Alison N Kurimchak, James S Duncan, Jonathan Chernoff
KRAS mutation-selective requirement for ACSS2 in colorectal adenoma formation. Research square (2024)
Allison C Sharrow, Emily Megill, Amanda J Chen, Afifa Farooqi, Stacy McGonigal, Nadine Hempel, Nathaniel W Snyder, Ronald J Buckanovich, Katherine M Aird
Acetate drives ovarian cancer quiescence via ACSS2-mediated acetyl-CoA production. bioRxiv : the preprint server for biology (2024)
Roderick O'Connor, Bakir Valentić, Andre Kelly, Alexander Shestov, Zhiyang Gan, Feng Shen, Adam Chatoff, Alison Jaccard, Claudia Crispim, John Scholler, Simon Heeke, Nathaniel W Snyder, Saba Ghassemi, Nicholas Jones, Saar I Gill
The Glucose Transporter 5 Enhances CAR-T Cell Metabolic Function and Anti-tumour Durability. Research square (2024)
Naveen Kumar Tangudu, Raquel Buj, Hui Wang, Jiefei Wang, Aidan R Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Baixue Yang, Adam Chatoff, Claudia V Crispim, Peter Sajjakulnukit, Maureen A Lyons, Kristine L Cooper, Nadine Hempel, Costas Andreas Lyssiotis, Uma R Chandran, Nathaniel W Snyder, Katherine Marie Aird
De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression. Cancer research communications 4 (5) (2024)
Naveen Kumar Tangudu, Raquel Buj, Hui Wang, Jiefei Wang, Aidan R Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Baixue Yang, Adam Chatoff, Claudia V Crispim, Peter Sajjakulnukit, Maureen A Lyons, Kristine L Cooper, Nadine Hempel, Costas Andreas Lyssiotis, Uma R Chandran, Nathaniel W Snyder, Katherine Marie Aird
De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression. Cancer research communications (2024)
Apoorva Uboveja, Zhentai Huang, Raquel Buj, Amandine Amalric, Hui Wang, Naveen Kumar Tangudu, Aidan R Cole, Emily Megill, Daniel Kantner, Adam Chatoff, Hafsah Ahmad, Mariola M Marcinkiewicz, Julie A Disharoon, Sarah Graff, Erika S Dahl, Nadine Hempel, Wayne Stallaert, Simone Sidoli, Benjamin G Bitler, David T Long, Nathaniel W Snyder, Katherine Marie Aird
αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation. bioRxiv : the preprint server for biology (2024)
Apoorva Uboveja, Zhentai Huang, Raquel Buj, Amandine Amalric, Hui Wang, Naveen Kumar Tangudu, Aidan R Cole, Emily Megill, Daniel Kantner, Adam Chatoff, Hafsah Ahmad, Mariola M Marcinkiewicz, Julie A Disharoon, Sarah Graff, Erika S Dahl, Nadine Hempel, Wayne Stallaert, Simone Sidoli, Benjamin G Bitler, David T Long, Nathaniel W Snyder, Katherine Marie Aird
αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation. bioRxiv : the preprint server for biology (2024)
Charline Ogier, Akino Mercy Charles Solomon, Zhen Lu, Ludmila Recoules, Alena Klochkova, Linara Gabitova-Cornell, Battuya Bayarmagnai, Diana Restifo, Aizhan Surumbayeva, Debora Barbosa Vendramini-Costa, Alexander Y Deneka, Ralph Francescone, Anna C Lilly, Alyssa Sipman, Jaye C Gardiner, Tiffany Q Luong, Janusz Franco-Barraza, Nina Ibeme, Kathy Q Cai, Margret B Einarson, Emmanuelle Nicolas, Andrei Efimov, Emily Megill, Nathaniel W Snyder, Corinne Bousquet, Jerome Cros, Yunyun Zhou, Erica A Golemis, Bojana Gligorijevic, Jonathan Soboloff, Serge Y Fuchs, Edna Cukierman, Igor Astsaturov
Trogocytosis of cancer-associated fibroblasts promotes pancreatic cancer growth and immune suppression via phospholipid scramblase anoctamin 6 (ANO6). bioRxiv : the preprint server for biology (2023)
Luke T Izzo, Sophie Trefely, Christina Demetriadou, Jack M Drummond, Takuya Mizukami, Nina Kuprasertkul, Aimee T Farria, Phuong T T Nguyen, Nivitha Murali, Lauren Reich, Daniel S Kantner, Joshua Shaffer, Hayley C Affronti, Alessandro Carrer, Andrew Andrews, Brian C Capell, Nathaniel W Snyder, Kathryn E Wellen
Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis. Science advances 9 (18) (2023)
Luke T Izzo, Sophie Trefely, Christina Demetriadou, Jack M Drummond, Takuya Mizukami, Nina Kuprasertkul, Aimee T Farria, Phuong T T Nguyen, Nivitha Murali, Lauren Reich, Daniel S Kantner, Joshua Shaffer, Hayley C Affronti, Alessandro Carrer, Andrew Andrews, Brian C Capell, Nathaniel W Snyder, Kathryn E Wellen
Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis. Science advances 9 (18) (2023)
Nathaniel W Snyder, Jordan L Meier
Metabolic regulation of epigenetic drug resistance. Nature chemical biology (2023)
Marissa N Trujillo, Erin Q Jennings, Emely A Hoffman, Hao Zhang, Aiden M Phoebe, Grace E Mastin, Naoya Kitamura, Julie A Reisz, Emily Megill, Daniel S Kantner, Mariola M Marcinkiewicz, Shannon M Twardy, Felicidad Lebario, Eli Chapman, Rebecca L McCullough, Angelo D'Alessandro, Nathaniel W Snyder, Darren A Cusanovich, James J Galligan
Lactoylglutathione promotes inflammatory signaling in macrophages. bioRxiv : the preprint server for biology (2023)
Frank Cichocki, Bin Zhang, Cheng-Ying Wu, Emily Chiu, Abderrahman Day, Roderick O'Connor, Dima Yackoubov, Ronit Simantov, David H McKenna, Qing Cao, Todd E DeFor, Murali Janakiram, Rose Wangen, Zuzan Cayci, Nathaniel W Snyder, Akhilesh Kumar, Bartosz J Grzywacz, Justin H Hwang, Yona Geffen, Jeffrey S Miller, Joseph E Maakaron, Veronika Bachanova
Nicotinamide enhances natural killer cell function and yields remissions in patients with non-Hodgkin lymphoma. Science translational medicine 15 (705) (2023)
Jonathan M Weiss, Erika M Palmieri, Marieli Gonzalez-Cotto, Ian A Bettencourt, Emily L Megill, Nathaniel W Snyder, Daniel W McVicar
Itaconic acid underpins hepatocyte lipid metabolism in non-alcoholic fatty liver disease in male mice. Nature metabolism (2023)
Daniel S Kantner, Anna Bostwick, Vicky Yang, Emily Megill, Carmen Bekeova, Erin Seifert, Nathaniel W Snyder
Comparison of colorimetric, fluorometric, and liquid chromatography-mass spectrometry assays for acetyl-coenzyme A. bioRxiv : the preprint server for biology (2023)
Huairui Yuan, Xujia Wu, Qiulian Wu, Adam Chatoff, Emily Megill, Jinjun Gao, Tengfei Huang, Tingting Duan, Kailin Yang, Chunyu Jin, Fanen Yuan, Shuai Wang, Linjie Zhao, Pascal O Zinn, Kalil G Abdullah, Yingming Zhao, Nathaniel W Snyder, Jeremy N Rich
Lysine catabolism reprograms tumour immunity through histone crotonylation. Nature (2023)
Christina Demetriadou, Andrew A Gibb, John W Elrod, Nathaniel W Snyder
Propionyl-CoA metabolism links chromatin acylation to cardiac transcription. Nature cardiovascular research 2 (12) (2023)
Whitney K Lieberman, Zachary A Brown, Daniel S Kantner, Yihang Jing, Emily Megill, Nya D Evans, McKenna C Crawford, Isita Jhulki, Carissa Grose, Jane E Jones, Nathaniel W Snyder, Jordan L Meier
Chemoproteomics Yields a Selective Molecular Host for Acetyl-CoA. Journal of the American Chemical Society (2023)
Christina Demetriadou, Andrew A Gibb, John W Elrod, Nathaniel W Snyder
Propionyl-CoA metabolism links chromatin acylation to cardiac transcription. Nature cardiovascular research 2 (12) (2023)
Patrick Lundgren, Prateek V Sharma, Lenka Dohnalová, Kyle Coleman, Giulia T Uhr, Susanna Kircher, Lev Litichevskiy, Klaas Bahnsen, Hélène C Descamps, Christina Demetriadou, Jacqueline Chan, Karthikeyani Chellappa, Timothy O Cox, Yael Heyman, Sarshan R Pather, Clarissa Shoffler, Christopher Petucci, Ophir Shalem, Arjun Raj, Joseph A Baur, Nathaniel W Snyder, Kathryn E Wellen, Maayan Levy, Patrick Seale, Mingyao Li, Christoph A Thaiss
A subpopulation of lipogenic brown adipocytes drives thermogenic memory. Nature metabolism (2023)
Luke T Izzo, Sophie Trefely, Christina Demetriadou, Jack M Drummond, Takuya Mizukami, Nina Kuprasertkul, Aimee T Farria, Phuong T T Nguyen, Nivitha Murali, Lauren Reich, Daniel S Kantner, Joshua Shaffer, Hayley C Affronti, Alessandro Carrer, Andrew Andrews, Brian C Capell, Nathaniel W Snyder, Kathryn E Wellen
Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis. Science advances 9 (18) (2023)
Luke T Izzo, Sophie Trefely, Christina Demetriadou, Jack M Drummond, Takuya Mizukami, Nina Kuprasertkul, Aimee T Farria, Phuong T T Nguyen, Nivitha Murali, Lauren Reich, Daniel S Kantner, Joshua Shaffer, Hayley C Affronti, Alessandro Carrer, Andrew Andrews, Brian C Capell, Nathaniel W Snyder, Kathryn E Wellen
Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis. Science advances 9 (18) (2023)
Xuepeng Wei, Kollin Schultz, Hannah L Pepper, Emily Megill, Austin Vogt, Nathaniel W Snyder, Ronen Marmorstein
Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nature communications 14 (1) (2023)
Christina Demetriadou, Andrew A Gibb, John W Elrod, Nathaniel W Snyder
Propionyl-CoA metabolism links chromatin acylation to cardiac transcription. Nature cardiovascular research 2 (12) (2023)
Carmen Bekeova, Ji In Han, Heli Xu, Evan Kerr, Brittney Blackburne, Shannon C Lynch, Clementina A Mesaros, Marta Murgia, Rajanikanth Vadigepalli, Joris Beld, Roberta Leonardi, Nathaniel W Snyder, Erin L Seifert
Acyl-CoA thioesterase-2 facilitates β-oxidation in glycolytic skeletal muscle in a lipid supply dependent manner. bioRxiv : the preprint server for biology (2023)
Sharon Anderson, Peining Xu, Alexander J Frey, Jason R Goodspeed, Mary T Doan, John J Orris, Nicolle Clements, Michael J Glassner, Nathaniel W Snyder
Cumulus cell acetyl-CoA metabolism from acetate is associated with maternal age but only partially with oocyte maturity. Systems biology in reproductive medicine 68 (1) (2021)
Dina Terloyeva, Alexander J Frey, Bo Y Park, Elizabeth M Kauffman, Leny Mathew, Anna Bostwick, Erika L Varner, Brian K Lee, Lisa A Croen, Margaret D Fallin, Irva Hertz-Picciotto, Craig J Newschaffer, Kristen Lyall, Nathaniel W Snyder
Meconium androgens are correlated with ASD-related phenotypic traits in early childhood in a familial enriched risk cohort. Molecular autism 11 (1) (2020)
C Martinez Calejman, S Trefely, S W Entwisle, A Luciano, S M Jung, W Hsiao, A Torres, C M Hung, H Li, Nathaniel W Snyder, Judit Vill N, Kathryn E Wellen, D A Guertin
mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis. Nature communications 11 (1) (2020)
C Martinez Calejman, S Trefely, S W Entwisle, S W Entwisle, S M Jung, W Hsiao, A Torres, C M Hung, H Li, Nathaniel W Snyder, Judit Vill N, Kathryn E Wellen, D A Guertin
Author Correction: mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis. Nature communications 11 (1) (2020)
Elyce Cardonick, Robert Broadrup, Peining Xu, Mary T Doan, Helen Jiang, Nathaniel W Snyder
Preliminary results of identification and quantification of paclitaxel and its metabolites in human meconium from newborns with gestational chemotherapeutic exposure. PloS one 14 (2) (2019)
Erika S Dahl, Raquel Buj, Kelly E Leon, Jordan M Newell, Yuka Imamura, Benjamin G Bitler, Nathaniel W Snyder, Katherine M Aird
Targeting IDH1 as a Prosenescent Therapy in High-grade Serous Ovarian Cancer. Molecular cancer research : MCR 17 (8) (2019)
Alessandro Carrer, Sophie Trefely, Steven Zhao, Sydney L Campbell, Robert J Norgard, Kollin C Schultz, Simone Sidoli, Joshua L D Parris, Hayley C Affronti, Sharanya Sivanand, Shaun Egolf, Yogev Sela, Marco Trizzino, Alessandro Gardini, Benjamin A Garcia, Nathaniel W Snyder, Ben Z Stanger, Kathryn E Wellen
Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis. Cancer discovery 9 (3) (2019)
Sophie Trefely, Clementina Mesaros, Pening Xu, Mary T Doan, Helen Jiang, Oya Altinok, Zulfiya Orynbayeva, Nathaniel W Snyder
Artefactual formation of pyruvate from in-source conversion of lactate. Rapid communications in mass spectrometry : RCM (2018)
Carrie Sims, Noelle Salliant, Andrew J Worth, Robert Parry, Clementina Mesaros, Ian A Blair, Nathaniel W Snyder
Metabolic tracing analysis reveals substrate-specific metabolic deficits in platelet storage lesion. Transfusion 57 (11) (2017)
Wilson R Sinclair, Jonathan H Shrimp, Thomas T Zengeya, Rhushikesh A Kulkarni, Julie M Garlick, Hans Luecke, Andrew J Worth, Ian A Blair, Nathaniel W Snyder, Jordan L Meier
Bioorthogonal pro-metabolites for profiling short chain fatty acylation. Chemical science 9 (5) (2017)

Nathaniel W Snyder.css-eqlu8i{font-size:small;padding-left:4px;} (Nathaniel Snyder, N W Snyder)

Publication Activity (10 Years)

Top Topics

Top Venues

Nathaniel W Snyder (Nathaniel Snyder, N W Snyder)