Christian A Olsen

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 39

Top Venues

ACS chemical neuroscience

Nature chemistry

Biochemistry

The Journal of organic chemistry

University of Copenhagen

Danish University of Pharmaceutical Sciences (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Copenhagen

Denmark

Professor :: Department of Drug Design and Pharmacology

Technical University of Denmark

Denmark

Associate Professor :: Department of Chemistry

Scripps Research Institute

United States

Research Associate/postdoc :: Department of Chemistry

The Danish University of Pharmaceutical Sciences

Denmark

Assistant Professor (non-tenured) :: Department of Medicinal Chemistry

Education History

Danish University of Pharmaceutical Sciences

Denmark

PHD :: Medicinal Chemistry

Technical University of Denmark

Denmark

MSC :: Chemistry

Publications

Alan Santini, Elisa Tassinari, Eleonora Poeta, Manuela Loi, Elisabetta Ciani, Stefania Trazzi, Rebecca Piccarducci, Simona Daniele, Claudia Martini, Barbara Pagliarani, Andrea Tarozzi, Matteo Bersani, Francesca Spyrakis, Daniela Danková, Christian A Olsen, Roberto Soldati, Vincenzo Tumiatti, Serena Montanari, Angela De Simone, Andrea Milelli
First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer's Disease. ACS chemical neuroscience 15 (11) (2024)
Daniela Danková, Christian A Olsen
Reversing the charge of lysine by genetic code expansion. Nature chemistry 16 (6) (2024)
Tobias N Hansen, Daniela Danková, Michael Bæk, Linda Grlaš, Christian A Olsen
Sulfur(VI) Fluoride Exchange Chemistry in Solid-Phase Synthesis of Compound Arrays: Discovery of Histone Deacetylase Inhibitors. JACS Au 4 (5) (2024)
Benjamin S Bejder, Fabrizio Monda, Bengt H Gless, Martin S Bojer, Hanne Ingmer, Christian A Olsen
A short-lived peptide signal regulates cell-to-cell communication in Listeria monocytogenes. Communications biology 7 (1) (2024)
Alan Santini, Elisa Tassinari, Eleonora Poeta, Manuela Loi, Elisabetta Ciani, Stefania Trazzi, Rebecca Piccarducci, Simona Daniele, Claudia Martini, Barbara Pagliarani, Andrea Tarozzi, Matteo Bersani, Francesca Spyrakis, Daniela Danková, Christian A Olsen, Roberto Soldati, Vincenzo Tumiatti, Serena Montanari, Angela De Simone, Andrea Milelli
First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer's Disease. ACS chemical neuroscience (2024)
Daniela Danková, Christian A Olsen
Reversing the charge of lysine by genetic code expansion. Nature chemistry (2024)
Alan Santini, Elisa Tassinari, Eleonora Poeta, Manuela Loi, Elisabetta Ciani, Stefania Trazzi, Rebecca Piccarducci, Simona Daniele, Claudia Martini, Barbara Pagliarani, Andrea Tarozzi, Matteo Bersani, Francesca Spyrakis, Daniela Danková, Christian A Olsen, Roberto Soldati, Vincenzo Tumiatti, Serena Montanari, Angela De Simone, Andrea Milelli
First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer's Disease. ACS chemical neuroscience 15 (11) (2024)
Daniela Danková, Christian A Olsen
Reversing the charge of lysine by genetic code expansion. Nature chemistry 16 (6) (2024)
Di Zhang, Jinjun Gao, Zhijun Zhu, Qianying Mao, Zhiqiang Xu, Pankaj K Singh, Cornelius C Rimayi, Carlos Moreno-Yruela, Shuling Xu, Gongyu Li, Yi-Cheng Sin, Yue Chen, Christian A Olsen, Nathaniel W Snyder, Lunzhi Dai, Lingjun Li, Yingming Zhao
Lysine L-lactylation is the dominant lactylation isomer induced by glycolysis. Nature chemical biology (2024)
Benjamin S Bejder, Fabrizio Monda, Bengt H Gless, Martin S Bojer, Hanne Ingmer, Christian A Olsen
A short-lived peptide signal regulates cell-to-cell communication in Listeria monocytogenes. Communications biology 7 (1) (2024)
Alan Santini, Elisa Tassinari, Eleonora Poeta, Manuela Loi, Elisabetta Ciani, Stefania Trazzi, Rebecca Piccarducci, Simona Daniele, Claudia Martini, Barbara Pagliarani, Andrea Tarozzi, Matteo Bersani, Francesca Spyrakis, Daniela Danková, Christian A Olsen, Roberto Soldati, Vincenzo Tumiatti, Serena Montanari, Angela De Simone, Andrea Milelli
First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer's Disease. ACS chemical neuroscience 15 (11) (2024)
Tobias N Hansen, Daniela Danková, Michael Bæk, Linda Grlaš, Christian A Olsen
Sulfur(VI) Fluoride Exchange Chemistry in Solid-Phase Synthesis of Compound Arrays: Discovery of Histone Deacetylase Inhibitors. JACS Au 4 (5) (2024)
Bengt H Gless, Sabrina H Schmied, Benjamin S Bejder, Christian A Olsen
Förster Resonance Energy Transfer Assay for Investigating the Reactivity of Thioesters in Biochemistry and Native Chemical Ligation. JACS Au 3 (5) (2023)
Julie E Bolding, Pablo Martín-Gago, Nima Rajabi, Luke F Gamon, Tobias N Hansen, Christian R O Bartling, Kristian Strømgaard, Michael Jonathan Davies, Christian A Olsen
Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase. Angewandte Chemie (International ed. in English) 61 (47) (2022)
Nima Rajabi, Tobias N Hansen, Alexander L Nielsen, Huy T Nguyen, Michael Bæk, Julie E Bolding, Oskar Ø Bahlke, Sylvester E G Petersen, Christian R O Bartling, Kristian Stro Mgaard, Christian A Olsen
Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme. Angewandte Chemie (International ed. in English) 61 (22) (2022)
Carlos Moreno-Yruela, Di Zhang, Wei Wei, Michael Bæk, Wenchao Liu, Jinjun Gao, Daniela Danková, Alexander L Nielsen, Julie E Bolding, Lu Yang, Samuel T Jameson, Jiemin Wong, Christian A Olsen, Yingming Zhao
Class I histone deacetylases (HDAC1-3) are histone lysine delactylases. Science advances 8 (3) (2022)
Carlos Moreno-Yruela, Christian A Olsen
Determination of Slow-Binding HDAC Inhibitor Potency and Subclass Selectivity. ACS medicinal chemistry letters 13 (5) (2022)
Carlos Moreno-Yruela, Michael Bæk, Fabrizio Monda, Christian A Olsen
Chiral Posttranslational Modification to Lysine ε-Amino Groups. Accounts of chemical research 55 (10) (2022)
Kathrin S Troelsen, Michael Bæk, Alexander L Nielsen, Andreas S Madsen, Nima Rajabi, Christian A Olsen
Mitochondria-targeted inhibitors of the human SIRT3 lysine deacetylase. RSC chemical biology 2 (2) (2021)
Alexander L Nielsen, Nima Rajabi, Norio Kudo, Kathrine Lundø, Carlos Moreno-Yruela, Michael Bæk, Martin Fontenas, Alessia Lucidi, Andreas S Madsen, Minoru Yoshida, Christian A Olsen
Mechanism-based inhibitors of SIRT2: structure-activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer cell migration. RSC chemical biology 2 (2) (2021)
Carlos Moreno-Yruela, Michael Bæk, Adela-Eugenie Vrsanova, Clemens Schulte, Hans Michael Maric, Christian A Olsen
Hydroxamic acid-modified peptide microarrays for profiling isozyme-selective interactions and inhibition of histone deacetylases. Nature communications 12 (1) (2021)
Bengt H Gless, Benjamin S Bejder, Fabrizio Monda, Martin S Bojer, Hanne Ingmer, Christian A Olsen
Rearrangement of Thiodepsipeptides by S → N Acyl Shift Delivers Homodetic Autoinducing Peptides. Journal of the American Chemical Society 143 (28) (2021)
Timothy Lynagh, Stephan Kiontke, Maria Meyhoff-Madsen, Bengt H Gless, Jónas Johannesen, Sabrina Kattelmann, Anders Christiansen, Martin Dufva, Andreas H Laustsen, Kanchan Devkota, Christian A Olsen, Daniel Kümmel, Stephan Alexander Pless, Brian Lohse
Peptide Inhibitors of the α-Cobratoxin-Nicotinic Acetylcholine Receptor Interaction. Journal of medicinal chemistry 63 (22) (2020)
Isabelle Wellhöfer, Janina Beck, Karla A Frydenvang, Stefan Bräse, Christian A Olsen
Increasing the Functional Group Diversity in Helical β-Peptoids: Achievement of Solvent- and pH-Dependent Folding. The Journal of organic chemistry 85 (16) (2020)
Michael Baek, Pablo Martín-Gago, Jonas S Laursen, Julie L H Madsen, Saswati Chakladar, Christian A Olsen
Photo Cross-Linking Probes Containing ϵ-N-Thioacyllysine and ϵ-N-Acyl-(δ-aza)lysine Residues. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (17) (2020)
Alexander L Nielsen, Christian A Olsen
Finding the gas pedal on a slow sirtuin. The Journal of biological chemistry 295 (5) (2020)
Bengt H Gless, Martin S Bojer, Pai Peng, Mara Baldry, Hanne Ingmer, Christian A Olsen
Identification of autoinducing thiodepsipeptides from staphylococci enabled by native chemical ligation. Nature chemistry 11 (5) (2019)
Carlos Moreno-Yruela, Daniel M Fass, Chialin Cheng, Joachim Herz, Christian A Olsen, Stephen J Haggarty
Kinetic Tuning of HDAC Inhibitors Affords Potent Inducers of Progranulin Expression. ACS chemical neuroscience 10 (8) (2019)
Isabelle Wellhöfer, Karla A Frydenvang, Simona Kotesova, Andreas M Christiansen, Jonas S Laursen, Christian A Olsen
Functionalized Helical β-Peptoids. The Journal of organic chemistry 84 (7) (2019)
Paul Santner, João Miguel da Silva Martins, Jonas S Laursen, Lars Behrendt, Leise Riber, Christian A Olsen, Isaiah T Arkin, Jakob Rahr Winther, Martin Willemoës, Kresten Lindorff-Larsen
A Robust Proton Flux (pHlux) Assay for Studying the Function and Inhibition of the Influenza A M2 Proton Channel. Biochemistry 57 (41) (2018)
Bengt H Gless, Christian A Olsen
Direct Peptide Cyclization and One-Pot Modification Using the MeDbz Linker. The Journal of organic chemistry 83 (17) (2018)
Sita V Olesen, Nima Rajabi, Birte Svensson, Christian A Olsen, Andreas S Madsen
An NAD+-Dependent Sirtuin Depropionylase and Deacetylase (Sir2La) from the Probiotic Bacterium Lactobacillus acidophilus NCFM. Biochemistry 57 (26) (2018)
Pablo Martín-Gago, Christian A Olsen
Arylfluorosulfate-Based Electrophiles for Covalent Protein Labeling: A New Addition to the Arsenal. Angewandte Chemie (International ed. in English) 58 (4) (2018)
Jens Engel-Andreasen, Isabelle Wellhöfer, Kathrine Wich, Christian A Olsen
Backbone-Fluorinated 1,2,3-Triazole-Containing Dipeptide Surrogates. The Journal of organic chemistry 82 (21) (2018)
Paul Santner, João Miguel da Silva Martins, Caroline Kampmeyer, Rasmus Hartmann-Petersen, Jonas S Laursen, Amelie Stein, Christian A Olsen, Isaiah T Arkin, Jakob Rahr Winther, Martin Willemoës, Kresten Lindorff-Larsen
Random Mutagenesis Analysis of the Influenza A M2 Proton Channel Reveals Novel Resistance Mutants. Biochemistry 57 (41) (2018)
Betül Kitir, Alex R Maolanon, Ragnhild G Ohm, Ana R Colaço, Peter Fristrup, Andreas S Madsen, Christian A Olsen
Chemical Editing of Macrocyclic Natural Products and Kinetic Profiling Reveal Slow, Tight-Binding Histone Deacetylase Inhibitors with Picomolar Affinities. Biochemistry 56 (38) (2017)
Bengt H Gless, Pai Peng, Katja D Pedersen, Charlotte H Gotfredsen, Hanne Ingmer, Christian A Olsen
Structure-Activity Relationship Study Based on Autoinducing Peptide (AIP) from Dog Pathogen S. schleiferi. Organic letters 19 (19) (2017)
Nima Rajabi, Marina Auth, Kathrin R Troelsen, Martin Pannek, Dhaval P Bhatt, Martin Fontenas, Matthew D Hirschey, Clemens Steegborn, Andreas S Madsen, Christian A Olsen
Mechanism-Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure-Activity Relationship, Biostructural, and Kinetic Insight. Angewandte Chemie (International ed. in English) 56 (47) (2017)
Alex R Maolanon, Helle M E Kristensen, Luke J Leman, M Reza Ghadiri, Christian A Olsen
Natural and Synthetic Macrocyclic Inhibitors of the Histone Deacetylase Enzymes. Chembiochem : a European journal of chemical biology 18 (1) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Christian A Olsen