Lukas E Dow (Lukas Dow)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 28

Top Topics

Endothelial Cells

Top Venues

Cancer discovery

Cancer research

bioRxiv : the preprint server for biology

Science translational medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Sarah Z Hanif, CheukMan Cherie Au, Ingrid Torregroza, Syeda Y Jannath, Tabassum Fabiha, Bhavneet Bhinder, Michael P Washburn, Dominic Devost, Shuchen Liu, Priya Bhardwaj, Todd Evans, Pradeep Kumar Anand, Robert Tarran, Sailesh Palikhe, Olivier Elemento, Lukas E Dow, John Blenis, Terence E Hébert, Kristy A Brown
The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization. bioRxiv : the preprint server for biology (2024)
Sarah Z Hanif, CheukMan Cherie Au, Ingrid Torregroza, Syeda Y Jannath, Tabassum Fabiha, Bhavneet Bhinder, Michael P Washburn, Dominic Devost, Shuchen Liu, Priya Bhardwaj, Todd Evans, Pradeep Kumar Anand, Robert Tarran, Sailesh Palikhe, Olivier Elemento, Lukas E Dow, John Blenis, Terence E Hébert, Kristy A Brown
The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization. bioRxiv : the preprint server for biology (2024)
Camino Bermejo-Rodriguez, Joaquín Araos Henríquez, Giuseppina Caligiuri, Sara Pinto Teles, Youngkyu Park, Anthony Evans, Lawrence N Barrera, Albrecht Neesse, Robert Grützmann, Daniela E Aust, Petra Rümmele, Thomas Knösel, Masako Narita, Masashi Narita, Fiona Campbell, Daniel Öhlund, Christian Pilarsky, Lukas E Dow, Patrick O Humbert, Giulia Biffi, David A Tuveson, Pedro A Perez-Mancera
Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis. Cancer research (2024)
Kevan Chu, Lukas E Dow
Adding new dimensions to 3D cancer models. Cancer research (2024)
Kevan Chu, Lukas E Dow
Adding New Dimensions to 3D Cancer Models. Cancer research 84 (6) (2024)
Stefan R Torborg, Olivera Grbovic-Huezo, Anupriya Singhal, Matilda Holm, Katherine Wu, Xuexiang Han, Yu-Jui Ho, Caj Haglund, Michael J Mitchell, Scott W Lowe, Lukas E Dow, Kenneth L Pitter, Francisco J Sánchez Rivera, Andre Levchenko, Tuomas Tammela
Solid tumor growth depends on an intricate equilibrium of malignant cell states. bioRxiv : the preprint server for biology (2023)
Alyna Katti, Adrián Vega-Pérez, Miguel Foronda, Jill Zimmerman, Maria Paz Zafra, Elizabeth Granowsky, Sukanya Goswami, Eric E Gardner, Bianca J Diaz, Janelle M Simon, Alexandra Wuest, Wei Luan, Maria Teresa Calvo Fernandez, Anastasia P Kadina, John A Walker, Kevin Holden, Scott W Lowe, Francisco J Sánchez Rivera, Lukas E Dow
Generation of precision preclinical cancer models using regulated in vivo base editing. Nature biotechnology (2023)
Priya Bhardwaj, Neil M Iyengar, Heba M Zahid, Katharine M Carter, Dong Jun Byun, Man Ho Choi, Qi Sun, Oleksandr Savenkov, Charalambia Louka, Catherine Liu, Phoebe Piloco, Monica Acosta, Rohan Bareja, Olivier Elemento, Miguel Foronda, Lukas E Dow, Sofya Oshchepkova, Dilip D Giri, Michael N Pollak, Xi Kathy Zhou, Benjamin D Hopkins, Ashley M Laughney, Melissa K Frey, Lora Hedrick Ellenson, Monica Morrow, Jason A Spector, Lewis C Cantley, Kristy A Brown
Obesity promotes breast epithelium DNA damage in women carrying a germline mutation in BRCA1 or BRCA2 . Science translational medicine 15 (684) (2023)
Priya Bhardwaj, Neil M Iyengar, Heba M Zahid, Katharine M Carter, Dong Jun Byun, Man Ho Choi, Qi Sun, Oleksandr Savenkov, Charalambia Louka, Catherine Liu, Phoebe Piloco, Monica Acosta, Rohan Bareja, Olivier Elemento, Miguel Foronda, Lukas E Dow, Sofya Oshchepkova, Dilip D Giri, Michael N Pollak, Xi Kathy Zhou, Benjamin D Hopkins, Ashley M Laughney, Melissa K Frey, Lora Hedrick Ellenson, Monica Morrow, Jason A Spector, Lewis C Cantley, Kristy A Brown
Obesity promotes breast epithelium DNA damage in women carrying a germline mutation in BRCA1 or BRCA2 . Science translational medicine 15 (684) (2023)
Lily M Blair, Joseph M Juan, Lafia Sebastian, Vy B Tran, Wensheng Nie, Gregory D Wall, Mehmet Gerceker, Ian K Lai, Edwin A Apilado, Gabriel Grenot, David Amar, Giorgia Foggetti, Mariana Do Carmo, Zeynep Ugur, Debbie Deng, Alex Chenchik, Maria Paz Zafra, Lukas E Dow, Katerina Politi, Jonathan J MacQuitty, Dmitri A Petrov, Monte M Winslow, Michael J Rosen, Ian P Winters
Oncogenic context shapes the fitness landscape of tumor suppression. Nature communications 14 (1) (2023)
Francisco J Sánchez Rivera, Lukas E Dow
How CRISPR Is Revolutionizing the Generation of New Models for Cancer Research. Cold Spring Harbor perspectives in medicine (2023)
Priya Bhardwaj, Neil M Iyengar, Heba M Zahid, Katharine M Carter, Dong Jun Byun, Man Ho Choi, Qi Sun, Oleksandr Savenkov, Charalambia Louka, Catherine Liu, Phoebe Piloco, Monica Acosta, Rohan Bareja, Olivier Elemento, Miguel Foronda, Lukas E Dow, Sofya Oshchepkova, Dilip D Giri, Michael N Pollak, Xi Kathy Zhou, Benjamin D Hopkins, Ashley M Laughney, Melissa K Frey, Lora Hedrick Ellenson, Monica Morrow, Jason A Spector, Lewis C Cantley, Kristy A Brown
Obesity promotes breast epithelium DNA damage in women carrying a germline mutation in BRCA1 or BRCA2 . Science translational medicine 15 (684) (2023)
Zhuxuan Li, Xueqian Zhuang, Chun-Hao Pan, Yan Yan, Rohit Thummalapalli, Jill Hallin, Stefan R Torborg, Anupriya Singhal, Jason C Chang, Eusebio Manchado, Lukas E Dow, Rona Yaeger, James G Christensen, Scott W Lowe, Charles M Rudin, Simon Joost, Tuomas Tammela
Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma. Cancer discovery (2023)
Alyna Katti, Bianca J Diaz, Christina M Caragine, Neville E Sanjana, Lukas E Dow
CRISPR in cancer biology and therapy. Nature reviews. Cancer 22 (5) (2022)
Francisco J Sánchez-Rivera, Bianca J Diaz, Edward R Kastenhuber, Henri Schmidt, Alyna Katti, Margaret C Kennedy, Vincent Tem, Yu-Jui Ho, Josef Leibold, Stella V Paffenholz, Francisco M Barriga, Kevan Chu, Sukanya Goswami, Alexandra N Wuest, Janelle M Simon, Kaloyan M Tsanov, Debyani Chakravarty, Hongxin Zhang, Christina S Leslie, Scott W Lowe, Lukas E Dow
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants. Nature biotechnology 40 (6) (2022)
Marie J Parsons, Tuomas Tammela, Lukas E Dow
WNT as a Driver and Dependency in Cancer. Cancer discovery 11 (10) (2021)
Samuel R Taylor, Shakti Ramsamooj, Roger J Liang, Alyna Katti, Rita Pozovskiy, Neil Vasan, Seo-Kyoung Hwang, Navid Nahiyaan, Nancy J Francoeur, Emma M Schatoff, Jared L Johnson, Manish A Shah, Andrew J Dannenberg, Robert P Sebra, Lukas E Dow, Lewis C Cantley, Kyu Y Rhee, Marcus DaSilva Goncalves
Dietary fructose improves intestinal cell survival and nutrient absorption. Nature 597 (7875) (2021)
Salvador Alonso, Lukas E Dow
Engineering chromosome rearrangements in cancer. Disease models & mechanisms 14 (9) (2021)
David C Montrose, Suchandrima Saha, Miguel Foronda, Erin M McNally, Qiuying Chen, Xi Kathy Zhou, Taehoon Ha, Jan Krumsiek, Mustafa Buyukozkan, Akanksha Verma, Olivier Elemento, Rhonda K Yantiss, Steven S Gross, Lorenzo Galluzzi, Lukas E Dow, Andrew J Dannenberg
Exogenous and Endogenous Sources of Serine Contribute to Colon Cancer Metabolism, Growth, and Resistance to 5-Fluorouracil. Cancer research 81 (9) (2021)
Alex Doan, Julia Arand, Diana Gong, Alexandros P Drainas, Yan Ting Shue, Myung Chang Lee, Shuyuan Zhang, David M Walter, Andrea C Chaikovsky, David M Feldser, Hannes Vogel, Lukas E Dow, Jan M Skotheim, Julien Sage
RB depletion is required for the continuous growth of tumors initiated by loss of RB. PLoS genetics 17 (12) (2021)
Maria Paz Zafra, Lukas E Dow
Revealing ARID1A Function in Gastric Cancer from the Bottom Up. Cancer discovery 11 (6) (2021)
Alyna Katti, Lukas E Dow
Base editing goes into hyperdrive. Nature cell biology 22 (6) (2020)
Teng Han, Sukanya Goswami, Yang Hu, Fanying Tang, Maria Paz Zafra, Charles Murphy, Zhen Cao, John T Poirier, Ekta Khurana, Olivier Elemento, Jaclyn F Hechtman, Karuna Ganesh, Rona Yaeger, Lukas E Dow
Lineage Reversion Drives WNT Independence in Intestinal Cancer. Cancer discovery 10 (10) (2020)
Laura Hinze, Roxane Labrosse, James Degar, Teng Han, Emma M Schatoff, Sabine Schreek, Salmaan Karim, Connor McGuckin, Joshua R Sacher, Florence Wagner, Martin Stanulla, Chen Yuan, Ewa Sicinska, Marios Giannakis, Kimmie Ng, Lukas E Dow, Alejandro Gutierrez
Exploiting the Therapeutic Interaction of WNT Pathway Activation and Asparaginase for Colorectal Cancer Therapy. Cancer discovery 10 (11) (2020)
Maria Paz Zafra, Marie J Parsons, Jangkyung Kim, Direna Alonso-Curbelo, Sukanya Goswami, Emma M Schatoff, Teng Han, Alyna Katti, Maria Teresa Calvo Fernandez, John E Wilkinson, Elena Piskounova, Lukas E Dow
An In Vivo Kras Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants. Cancer discovery 10 (11) (2020)
Josef Leibold, Marcus Ruscetti, Zhen Cao, Yu-Jui Ho, Timour Baslan, Min Zou, Wassim Abida, Judith Feucht, Teng Han, Francisco M Barriga, Kaloyan M Tsanov, Leah B Zamechek, Amanda Kulick, Corina Amor, Sha Tian, Katarzyna Rybczyk, Nelson R Salgado, Francisco J Sánchez Rivera, Philip A Watson, Elisa de Stanchina, John E Wilkinson, Lukas E Dow, Cory Abate-Shen, Charles L Sawyers, Scott W Lowe
Somatic Tissue Engineering in Mouse Models Reveals an Actionable Role for WNT Pathway Alterations in Prostate Cancer Metastasis. Cancer discovery 10 (7) (2020)
Brisa Palikuqi, Duc-Huy T Nguyen, Ge Li, Ryan Schreiner, Alessandro Filippo Pellegata, Ying Liu, David Redmond, Fuqiang Geng, Yang Lin, Jesus Maria Gomez Salinero, Masataka Yokoyama, Paul Zumbo, Tuo Zhang, Balvir Kunar, Mavee Witherspoon, Teng Han, Alfonso M Tedeschi, Federico Scottoni, Steven M Lipkin, Lukas E Dow, Olivier Elemento, Jenny Z Xiang, Koji Shido, Jason R Spence, Qiao J Zhou, Robert E Schwartz, Paolo de Coppi, Sina Y Rabbany, Shahin Rafii
Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis. Nature 585 (7825) (2020)
Miguel Foronda, Yusuke Tarumoto, Emma M Schatoff, Benjamin I Leach, Bianca J Diaz, Jill Zimmerman, Sukanya Goswami, Michael Shusterman, Christopher R Vakoc, Lukas E Dow
Tankyrase inhibition sensitizes cells to CDK4 blockade. PloS one 14 (12) (2019)