Niu Huang

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 36

Top Venues

Journal of chemical information and modeling

Nature communications

International journal of molecular sciences

ACS pharmacology & translational science

National Institute of Biological Sciences, Beijing

University of Maryland, Baltimore (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

National Institute of Biological Sciences, Beijing

China

Principle Investigator

UCSF

United States

Postdoc :: Pharmaceutical Chemistry

Institute of Material Medica

China

Assistant Researcher :: Medicinal Chemistry

Education History

University of Maryland, Baltimore

United States

PHD :: Pharmaceutical Sciences

Nankai University

China

BSC :: Physics

Publications

Qing Wang, Xuegang Fu, Yuting Yan, Tao Liu, Yuting Xie, Xiaoqing Song, Yu Zhou, Min Xu, Ping Wang, Peng Fu, Jianhui Huang, Niu Huang
Structure-Based Identification of Organoruthenium Compounds as Nanomolar Antagonists of Cannabinoid Receptors. Journal of chemical information and modeling 64 (3) (2024)
Qing Wang, Xuegang Fu, Yuting Yan, Tao Liu, Yuting Xie, Xiaoqing Song, Yu Zhou, Min Xu, Ping Wang, Peng Fu, Jianhui Huang, Niu Huang
Structure-Based Identification of Organoruthenium Compounds as Nanomolar Antagonists of Cannabinoid Receptors. Journal of chemical information and modeling (2024)
Xuelian Li, Cheng Shen, Hui Zhu, Yujian Yang, Qing Wang, Jincai Yang, Niu Huang
A High-Quality Data Set of Protein-Ligand Binding Interactions Via Comparative Complex Structure Modeling. Journal of chemical information and modeling 64 (7) (2024)
Xuelian Li, Cheng Shen, Hui Zhu, Yujian Yang, Qing Wang, Jincai Yang, Niu Huang
A High-Quality Data Set of Protein-Ligand Binding Interactions Via Comparative Complex Structure Modeling. Journal of chemical information and modeling 64 (7) (2024)
Ping Wang, Yang Li, Jinyi Yang, Ziwen Li, Xintong Ren, Qingshi Meng, Pengfei Li, Luzhe Qin, Wei Li, Yuting Xie, Nannan Hou, Niu Huang
Structure-Based Identification of Kelch-like ECH-Associated Protein 1 as a Pharmacological Target of Electrophile-Containing Catechol- O -Methyltransferase Inhibitors. ACS pharmacology & translational science 7 (3) (2024)
Qing Wang, Xuegang Fu, Yuting Yan, Tao Liu, Yuting Xie, Xiaoqing Song, Yu Zhou, Min Xu, Ping Wang, Peng Fu, Jianhui Huang, Niu Huang
Structure-Based Identification of Organoruthenium Compounds as Nanomolar Antagonists of Cannabinoid Receptors. Journal of chemical information and modeling 64 (3) (2024)
Qing Wang, Xuegang Fu, Yuting Yan, Tao Liu, Yuting Xie, Xiaoqing Song, Yu Zhou, Min Xu, Ping Wang, Peng Fu, Jianhui Huang, Niu Huang
Structure-Based Identification of Organoruthenium Compounds as Nanomolar Antagonists of Cannabinoid Receptors. Journal of chemical information and modeling 64 (3) (2024)
Xuelian Li, Cheng Shen, Hui Zhu, Yujian Yang, Qing Wang, Jincai Yang, Niu Huang
A High-Quality Data Set of Protein-Ligand Binding Interactions Via Comparative Complex Structure Modeling. Journal of chemical information and modeling 64 (7) (2024)
Xuelian Li, Cheng Shen, Hui Zhu, Yujian Yang, Qing Wang, Jincai Yang, Niu Huang
A High-Quality Data Set of Protein-Ligand Binding Interactions Via Comparative Complex Structure Modeling. Journal of chemical information and modeling (2024)
Ping Wang, Yang Li, Jinyi Yang, Ziwen Li, Xintong Ren, Qingshi Meng, Pengfei Li, Luzhe Qin, Wei Li, Yuting Xie, Nannan Hou, Niu Huang
Structure-Based Identification of Kelch-like ECH-Associated Protein 1 as a Pharmacological Target of Electrophile-Containing Catechol- O -Methyltransferase Inhibitors. ACS pharmacology & translational science 7 (3) (2024)
Qing Wang, Xuegang Fu, Yuting Yan, Tao Liu, Yuting Xie, Xiaoqing Song, Yu Zhou, Min Xu, Ping Wang, Peng Fu, Jianhui Huang, Niu Huang
Structure-Based Identification of Organoruthenium Compounds as Nanomolar Antagonists of Cannabinoid Receptors. Journal of chemical information and modeling 64 (3) (2024)
Qing Wang, Fanhao Meng, Yuting Xie, Wei Wang, Yumin Meng, Linjie Li, Tao Liu, Jianxun Qi, Xiaodan Ni, Sanduo Zheng, Jianhui Huang, Niu Huang
In Silico Discovery of Small Molecule Modulators Targeting the Achilles' Heel of SARS-CoV-2 Spike Protein. ACS central science 9 (2) (2023)
Yingying Nie, Zeming Qiu, Sijia Chen, Zhao Chen, Xiaocui Song, Yan Ma, Niu Huang, Brian J Laidlaw, Sanduo Zheng
Specific binding of GPR174 by endogenous lysophosphatidylserine leads to high constitutive G s signaling. Nature communications 14 (1) (2023)
Qing Wang, Fanhao Meng, Yuting Xie, Wei Wang, Yumin Meng, Linjie Li, Tao Liu, Jianxun Qi, Xiaodan Ni, Sanduo Zheng, Jianhui Huang, Niu Huang
In Silico Discovery of Small Molecule Modulators Targeting the Achilles' Heel of SARS-CoV-2 Spike Protein. ACS central science 9 (2) (2023)
Hui Zhu, Yulin Zhang, Wei Li, Niu Huang
A Comprehensive Survey of Prospective Structure-Based Virtual Screening for Early Drug Discovery in the Past Fifteen Years. International journal of molecular sciences 23 (24) (2022)
Guangchen Li, Yifu Cheng, Chi Han, Chun Song, Niu Huang, Yunfei Du
Pyrazole-containing pharmaceuticals: target, pharmacological activity, and their SAR studies. RSC medicinal chemistry 13 (11) (2022)
Jian-Hua Wang, Yu-Liang Tang, Zhou Gong, Rohit Jain, Fan Xiao, Yu Zhou, Dan Tan, Qiang Li, Niu Huang, Shu-Qun Liu, Keqiong Ye, Chun Tang, Meng-Qiu Dong, Xiaoguang Lei
Characterization of protein unfolding by fast cross-linking mass spectrometry using di-ortho-phthalaldehyde cross-linkers. Nature communications 13 (1) (2022)
Hui Zhu, Yulin Zhang, Wei Li, Niu Huang
A Comprehensive Survey of Prospective Structure-Based Virtual Screening for Early Drug Discovery in the Past Fifteen Years. International journal of molecular sciences 23 (24) (2022)
Hui Zhu, Jincai Yang, Niu Huang
Assessment of the Generalization Abilities of Machine-Learning Scoring Functions for Structure-Based Virtual Screening. Journal of chemical information and modeling 62 (22) (2022)
Hui Zhu, Yulin Zhang, Wei Li, Niu Huang
A Comprehensive Survey of Prospective Structure-Based Virtual Screening for Early Drug Discovery in the Past Fifteen Years. International journal of molecular sciences 23 (24) (2022)
Hui Zhu, Yulin Zhang, Wei Li, Niu Huang
A Comprehensive Survey of Prospective Structure-Based Virtual Screening for Early Drug Discovery in the Past Fifteen Years. International journal of molecular sciences 23 (24) (2022)
Xiao Teng, Sijia Chen, Qing Wang, Zhao Chen, Xiaoying Wang, Niu Huang, Sanduo Zheng
Structural insights into G protein activation by D1 dopamine receptor. Science advances 8 (23) (2022)
Min Xu, Cheng Shen, Jincai Yang, Qing Wang, Niu Huang
Systematic Investigation of Docking Failures in Large-Scale Structure-Based Virtual Screening. ACS omega 7 (43) (2022)
Pengcheng Han, Chao Su, Yanfang Zhang, Chongzhi Bai, Anqi Zheng, Chengpeng Qiao, Qing Wang, Sheng Niu, Qian Chen, Yuqin Zhang, Weiwei Li, Hanyi Liao, Jing Li, Zengyuan Zhang, Heecheol Cho, Mengsu Yang, Xiaoyu Rong, Yu Hu, Niu Huang, Jinghua Yan, Qihui Wang, Xin Zhao, George Fu Gao, Jianxun Qi
Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants. Nature communications 12 (1) (2021)
Dapeng Ju, Wei Zhang, Jiawei Yan, Haijiao Zhao, Wei Li, Jiawen Wang, Meimei Liao, Zhancong Xu, Zhiqiang Wang, Guanshen Zhou, Long Mei, Nannan Hou, Shuhua Ying, Tao Cai, She Chen, Xiaowen Xie, Luhua Lai, Chao Tang, Noheon Park, Joseph S Takahashi, Niu Huang, Xiangbing Qi, Eric Erquan Zhang
Chemical perturbations reveal that RUVBL2 regulates the circadian phase in mammals. Science translational medicine 12 (542) (2021)
Qing Wang, Yu Zhou, Jianhui Huang, Niu Huang
Structure, Function, and Pharmaceutical Ligands of 5-Hydroxytryptamine 2B Receptor. Pharmaceuticals (Basel, Switzerland) 14 (2) (2021)
Jie Chen, Nan Liu, Yinpin Huang, Yuanxun Wang, Yuxing Sun, Qingcui Wu, Dianrong Li, Shuanhu Gao, Hong-Wei Wang, Niu Huang, Xiangbing Qi, Xiaodong Wang
Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells. Nature communications 12 (1) (2021)
Gudong Li, Wei Zhang, Yuting Xie, Yang Li, Rao Cao, Guojun Zheng, Niu Huang, Yu Zhou
Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors. Journal of chemical information and modeling 60 (6) (2020)
Hong Lin, Xiaozhe Zhang, Li Liu, Qiuyu Fu, Chuanlong Zang, Yan Ding, Yang Su, Zhixue Xu, Sining He, Xiaoli Yang, Xiayun Wei, Haibin Mao, Yasong Cui, Yi Wei, Chuanzheng Zhou, Lilin Du, Niu Huang, Ning Zheng, Tao Wang, Feng Rao
Basis for metabolite-dependent Cullin-RING ligase deneddylation by the COP9 signalosome. Proceedings of the National Academy of Sciences of the United States of America 117 (8) (2020)
Shiming Peng, Wen Xiao, Dapeng Ju, Baofa Sun, Nannan Hou, Qianlan Liu, Yanli Wang, Haijiao Zhao, Chunchun Gao, Song Zhang, Ran Cao, Pengfei Li, Huanwei Huang, Yongfen Ma, Yankai Wang, Weiyi Lai, Zhixiong Ma, Wei Zhang, Song Huang, Hailin Wang, Zhiyuan Zhang, Liping Zhao, Tao Cai, Yong-Liang Zhao, Fengchao Wang, Yongzhan Nie, Gang Zhi, Yun-Gui Yang, Eric Erquan Zhang, Niu Huang
Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1. Science translational medicine 11 (488) (2020)
Lei Gao, Cong Su, Xiaoxia Du, Ruishan Wang, Shuming Chen, Yu Zhou, Chengwei Liu, Xiaojing Liu, Runze Tian, Liyun Zhang, Kebo Xie, She Chen, Qianqian Guo, Lanping Guo, Yoshio Hano, Manabu Shimazaki, Atsushi Minami, Hideaki Oikawa, Niu Huang, Kendall N Houk, Luqi Huang, Jun-Gui Dai, Xiaoguang Lei
FAD-dependent enzyme-catalysed intermolecular [4+2] cycloaddition in natural product biosynthesis. Nature chemistry 12 (7) (2020)
Yuanxun Wang, Qiuyu Fu, Yu Zhou, Yunfei Du, Niu Huang
Replacement of Protein Binding-Site Waters Contributes to Favorable Halogen Bond Interactions. Journal of chemical information and modeling 59 (7) (2019)
Alexander X Jones, Yong Cao, Yu-Liang Tang, Jian-Hua Wang, Yue-He Ding, Hui Tan, Zhen-Lin Chen, Run-Qian Fang, Jili Yin, Rong-Chang Chen, Xing Zhu, Yang She, Niu Huang, Feng Shao, Keqiong Ye, Rui-Xiang Sun, Si-Min He, Xiaoguang Lei, Meng-Qiu Dong
Improving mass spectrometry analysis of protein structures with arginine-selective chemical cross-linkers. Nature communications 10 (1) (2019)
Gudong Li, Wei Li, Yuting Xie, Xiaobo Wan, Guojun Zheng, Niu Huang, Yu Zhou
Discovery of Novel Pim-1 Kinase Inhibitors with a Flexible-Receptor Docking Protocol. Journal of chemical information and modeling 59 (10) (2019)
Ling Zhang, Hanzi Sun, Zhen Chen, Zhengsheng Liu, Niu Huang, Feng Qian
Intermolecular Interactions between Coencapsulated Drugs Inhibit Drug Crystallization and Enhance Colloidal Stability of Polymeric Micelles. Molecular pharmaceutics 14 (10) (2017)
Yanli Wang, Yuze Sun, Ran Cao, Dan Liu, Yuting Xie, Li Li, Xiangbing Qi, Niu Huang
In Silico Identification of a Novel Hinge-Binding Scaffold for Kinase Inhibitor Discovery. Journal of medicinal chemistry 60 (20) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Niu Huang