Feng Shao

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 40

Top Venues

Nature

Science (New York, N.Y.)

Nature structural & molecular biology

Nature communications

National Institute of Biological Sciences

University of Michigan (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

National Institute of Biological Sciences Jul 01 2005

China

Principle Investigator

Education History

University of Michigan Sep 01 1999 - Apr 30 2003

United States

PHD :: Biological Chemistry

Chinese Academy of Sciences Sep 01 1996 - Jun 30 1999

China

MSC :: Institute of Biophysics

Peking University Sep 01 1992 - Jun 30 1996

China

BSC :: Technical Physics

Publications

Chao Wei, Wei Jiang, Ruiyu Wang, Haoyu Zhong, Huabin He, Xinwei Gao, Shilin Zhong, Fengting Yu, Qingchun Guo, Li Zhang, Lisa D J Schiffelers, Bin Zhou, Martin Trepel, Florian Ingo Schmidt, Minmin Luo, Feng Shao
Brain endothelial GSDMD activation mediates inflammatory BBB breakdown. Nature (2024)
Yue Tang, Xiaoying Tian, Min Wang, Ying-Lu Cui, Yang She, Zhaoxiang Shi, Jiaqi Liu, Huijin Mao, Lilu Liu, Chao Li, Yuwei Zhang, Pengwei Li, Yue Ma, Jinyuan Sun, Qing Du, Jie Li, Jun Wang, De-Feng Li, Bian Wu, Feng Shao, Yihua Chen
The β-d- manno -heptoses are immune agonists across kingdoms. Science (New York, N.Y.) 385 (6709) (2024)
Yue Tang, Xiaoying Tian, Min Wang, Ying-Lu Cui, Yang She, Zhaoxiang Shi, Jiaqi Liu, Huijin Mao, Lilu Liu, Chao Li, Yuwei Zhang, Pengwei Li, Yue Ma, Jinyuan Sun, Qing Du, Jie Li, Jun Wang, De-Feng Li, Bian Wu, Feng Shao, Yihua Chen
The β-d- manno -heptoses are immune agonists across kingdoms. Science (New York, N.Y.) 385 (6709) (2024)
Yueyue Li, Yanjie Hou, Qi Sun, Huan Zeng, Fanyi Meng, Xiang Tian, Qun He, Feng Shao, Jingjin Ding
Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms. Science (New York, N.Y.) (2024)
Chao Wei, Wei Jiang, Ruiyu Wang, Haoyu Zhong, Huabin He, Xinwei Gao, Shilin Zhong, Fengting Yu, Qingchun Guo, Li Zhang, Lisa D J Schiffelers, Bin Zhou, Martin Trepel, Florian Ingo Schmidt, Minmin Luo, Feng Shao
Brain endothelial GSDMD activation mediates inflammatory BBB breakdown. Nature 629 (8013) (2024)
Yueyue Li, Yanjie Hou, Qi Sun, Huan Zeng, Fanyi Meng, Xiang Tian, Qun He, Feng Shao, Jingjin Ding
Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms. Science (New York, N.Y.) 384 (6697) (2024)
Chao Wei, Wei Jiang, Ruiyu Wang, Haoyu Zhong, Huabin He, Xinwei Gao, Shilin Zhong, Fengting Yu, Qingchun Guo, Li Zhang, Lisa D J Schiffelers, Bin Zhou, Martin Trepel, Florian Ingo Schmidt, Minmin Luo, Feng Shao
Brain endothelial GSDMD activation mediates inflammatory BBB breakdown. Nature (2024)
Chao Wei, Wei Jiang, Ruiyu Wang, Haoyu Zhong, Huabin He, Xinwei Gao, Shilin Zhong, Fengting Yu, Qingchun Guo, Li Zhang, Lisa D J Schiffelers, Bin Zhou, Martin Trepel, Florian Ingo Schmidt, Minmin Luo, Feng Shao
Brain endothelial GSDMD activation mediates inflammatory BBB breakdown. Nature (2024)
Chao Wei, Wei Jiang, Ruiyu Wang, Haoyu Zhong, Huabin He, Xinwei Gao, Shilin Zhong, Fengting Yu, Qingchun Guo, Li Zhang, Lisa D J Schiffelers, Bin Zhou, Martin Trepel, Florian Ingo Schmidt, Minmin Luo, Feng Shao
Brain endothelial GSDMD activation mediates inflammatory BBB breakdown. Nature 629 (8013) (2024)
Yueyue Li, Yanjie Hou, Qi Sun, Huan Zeng, Fanyi Meng, Xiang Tian, Qun He, Feng Shao, Jingjin Ding
Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms. Science (New York, N.Y.) 384 (6697) (2024)
Chao Wei, Wei Jiang, Ruiyu Wang, Haoyu Zhong, Huabin He, Xinwei Gao, Shilin Zhong, Fengting Yu, Qingchun Guo, Li Zhang, Lisa D J Schiffelers, Bin Zhou, Martin Trepel, Florian Ingo Schmidt, Minmin Luo, Feng Shao
Brain endothelial GSDMD activation mediates inflammatory BBB breakdown. Nature 629 (8013) (2024)
Kun Jiang, Weixun Li, Ming Tong, Jinghua Xu, Zhe Chen, Yan Yang, Yuanrong Zang, Xuyao Jiao, Shuang-Jiang Liu, Bentley Lim, Xianzhi Jiang, Jiawei Wang, Da-Lei Wu, Mingyu Wang, Shuang-Jiang Liu, Feng Shao, Xiang Gao
Bacteroides fragilis ubiquitin homologue drives intraspecies bacterial competition in the gut microbiome. Nature microbiology (2023)
Yanjie Hou, Huan Zeng, Zilin Li, Na Feng, Fanyi Meng, Yue Xu, Lin Li, Feng Shao, Jingjin Ding
Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nature structural & molecular biology 30 (3) (2023)
Xiu Zhong, Huan Zeng, Zhiwei Zhou, Ya Su, Hang Cheng, Yanjie Hou, Yang She, Na Feng, Jia Wang, Feng Shao, Jingjin Ding
Structural mechanisms for regulation of GSDMB pore-forming activity. Nature (2023)
Stefan Alexander Fattinger, Luca Maurer, Petra Geiser, Elliott M Bernard, Ursina Enz, Suwannee Ganguillet, Ersin Gül, Sanne Kroon, Benjamin Demarco, Vanessa Mack, Markus Furter, Manja Barthel, Pawel Pelczar, Feng Shao, Petr Broz, Mikael Erik Sellin, Wolf-Dietrich Hardt
Gasdermin D is the only Gasdermin that provides protection against acute Salmonella gut infection in mice. Proceedings of the National Academy of Sciences of the United States of America 120 (48) (2023)
Yanjie Hou, Huan Zeng, Zilin Li, Na Feng, Fanyi Meng, Yue Xu, Lin Li, Feng Shao, Jingjin Ding
Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nature structural & molecular biology (2023)
Yanjie Hou, Huan Zeng, Zilin Li, Na Feng, Fanyi Meng, Yue Xu, Lin Li, Feng Shao, Jingjin Ding
Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nature structural & molecular biology 30 (3) (2023)
Xiu Zhong, Huan Zeng, Zhiwei Zhou, Ya Su, Hang Cheng, Yanjie Hou, Yang She, Na Feng, Jia Wang, Feng Shao, Jingjin Ding
Structural mechanisms for regulation of GSDMB pore-forming activity. Nature (2023)
Yanjie Hou, Huan Zeng, Zilin Li, Na Feng, Fanyi Meng, Yue Xu, Lin Li, Feng Shao, Jingjin Ding
Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nature structural & molecular biology 30 (3) (2023)
Xuyan Shi, Qichao Sun, Yanjie Hou, Huan Zeng, Yong Cao, Meng-Qiu Dong, Jingjin Ding, Feng Shao
Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome. Nature (2023)
Yaxin Liu, Huan Zeng, Yanjie Hou, Zilin Li, Lin Li, Xiaocui Song, Jingjin Ding, Feng Shao, Yue Xu
Calmodulin Binding Activates Chromobacterium CopC Effector to ADP-Riboxanate Host Apoptotic Caspases. mBio 13 (3) (2022)
Shiyang Cao, Yang Jiao, Wei Jiang, Yarong Wu, Si Qin, Yifan Ren, Yang You, Yafang Tan, Xiao Guo, Hongyan Chen, Yuan Zhang, Gengshan Wu, Tong Wang, Yazhou Zhou, Ya-Jun Song, Yujun Cui, Feng Shao, Ruifu Yang, Zongmin Du
Subversion of GBP-mediated host defense by E3 ligases acquired during Yersinia pestis evolution. Nature communications 13 (1) (2022)
Wulf Tonnus, Francesca Maremonti, Alexia Belavgeni, Markus Latk, Yoshihiro Kusunoki, Anne Brucker, Anne von Mässenhausen, Claudia Meyer, Sophie Locke, Florian Gembardt, Kristina Beer, Paul Hoppenz, Jan U Becker, Christian Hugo, Hans-Joachim Anders, Stefan R Bornstein, Feng Shao, Andreas Linkermann
Gasdermin D-deficient mice are hypersensitive to acute kidney injury. Cell death & disease 13 (9) (2022)
Yue Xu, Sen Cheng, Huan Zeng, Ping Zhou, Yan Ma, Lin Li, Xiaoyun Liu, Feng Shao, Jingjin Ding
ARF GTPases activate Salmonella effector SopF to ADP-ribosylate host V-ATPase and inhibit endomembrane damage-induced autophagy. Nature structural & molecular biology 29 (1) (2022)
Zhan Zhang, Jun Zou, Zhenda Shi, Benyue Zhang, Lucie Etienne-Mesmin, Yanling Wang, Xuyan Shi, Feng Shao, Benoit Chassaing, Andrew T Gewirtz
IL-22-induced cell extrusion and IL-18-induced cell death prevent and cure rotavirus infection. Science immunology 5 (52) (2021)
Pilar Samperio Ventayol, Petra Geiser, Maria Letizia Di Martino, Alexandra Florbrant, Stefan Alexander Fattinger, Naemi Walder, Eduardo Sima, Feng Shao, Nelson O Gekara, Magnus Sundbom, Wolf-Dietrich Hardt, Dominic-Luc Webb, Per M Hellström, Jens Eriksson, Mikael Erik Sellin
Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers. Proceedings of the National Academy of Sciences of the United States of America 118 (16) (2021)
Zilin Li, Wang Liu, Jiaqi Fu, Sen Cheng, Yue Xu, Zhiqiang Wang, Xiaofan Liu, Xuyan Shi, Yaxin Liu, Xiangbing Qi, Xiaoyun Liu, Jingjin Ding, Feng Shao
Shigella evades pyroptosis by arginine ADP-riboxanation of caspase-11. Nature 599 (7884) (2021)
Kun Meng, Xiaohui Zhuang, Ting Peng, Shufan Hu, Jin Yang, Zhen Wang, Jiaqi Fu, Juan Xue, Xing Pan, Jun Lv, Xiaoyun Liu, Feng Shao, Shan Li
Arginine GlcNAcylation of Rab small GTPases by the pathogen Salmonella Typhimurium. Communications biology 3 (1) (2020)
Mausita Karmakar, Martin S Minns, Elyse N Greenberg, Jose Diaz-Aponte, Kersi Pestonjamasp, Jennifer L Johnson, Joseph K Rathkey, Derek W Abbott, Kun Wang, Feng Shao, Sergio D Catz, George R Dubyak, Eric Pearlman
N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis. Nature communications 11 (1) (2020)
Qinyang Wang, Yupeng Wang, Jingjin Ding, Chunhong Wang, Xuehan Zhou, Wenqing Gao, Huanwei Huang, Feng Shao, Zhibo Liu
A bioorthogonal system reveals antitumour immune function of pyroptosis. Nature 579 (7799) (2020)
Zhiwei Zhou, Huabin He, Kun Wang, Xuyan Shi, Yupeng Wang, Ya Su, Yao Wang, Da Li, Wang Liu, Yongliang Zhang, Lianjun Shen, Weidong Han, Lin Shen, Jingjin Ding, Feng Shao
Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells. Science (New York, N.Y.) 368 (6494) (2020)
Jie Ren, Yu Sang, Ran Qin, Yang Su, Zhongli Cui, Zhiguo Mang, Hao Li, Shaoyong Lu, Jian Zhang, Sen Cheng, Xiaoyun Liu, Jixi Li, Jie Lu, Wenjuan Wu, Guo-Ping Zhao, Feng Shao, Yu-Feng Yao
Metabolic intermediate acetyl phosphate modulates bacterial virulence via acetylation. Emerging microbes & infections 8 (1) (2019)
Petr Broz, Pablo Pelegrin, Feng Shao
The gasdermins, a protein family executing cell death and inflammation. Nature reviews. Immunology 20 (3) (2019)
Vijay A K Rathinam, Yue Zhao, Feng Shao
Innate immunity to intracellular LPS. Nature immunology 20 (5) (2019)
Alexander X Jones, Yong Cao, Yu-Liang Tang, Jian-Hua Wang, Yue-He Ding, Hui Tan, Zhen-Lin Chen, Run-Qian Fang, Jili Yin, Rong-Chang Chen, Xing Zhu, Yang She, Niu Huang, Feng Shao, Keqiong Ye, Rui-Xiang Sun, Si-Min He, Xiaoguang Lei, Meng-Qiu Dong
Improving mass spectrometry analysis of protein structures with arginine-selective chemical cross-linkers. Nature communications 10 (1) (2019)
Hao Xu, Jianjin Shi, Hang Gao, Ying Liu, Zhenxiao Yang, Feng Shao, Na Dong
The N-end rule ubiquitin ligase UBR2 mediates NLRP1B inflammasome activation by anthrax lethal toxin. The EMBO journal 38 (13) (2019)
Chenggong Ji, Shuo Du, Peng Li, Qinyu Zhu, Xiaoke Yang, Chunhong Long, Jin Yu, Feng Shao, Junyu Xiao
Structural mechanism for guanylate-binding proteins (GBPs) targeting by the Shigella E3 ligase IpaH9.8. PLoS pathogens 15 (6) (2019)
Ling Gao, Qitao Song, Hao Liang, Yuntao Zhu, Tiantian Wei, Na Dong, Junyu Xiao, Feng Shao, Luhua Lai, Xing Chen
Legionella effector SetA as a general O-glucosyltransferase for eukaryotic proteins. Nature chemical biology 15 (3) (2019)
Wang Liu, Yan Zhou, Tao Peng, Ping Zhou, Xiaojun Ding, Zilin Li, Haoyu Zhong, Yue Xu, She Chen, Howard C Hang, Feng Shao
Nε-fatty acylation of multiple membrane-associated proteins by Shigella IcsB effector to modulate host function. Nature microbiology 3 (9) (2018)
Jingjin Ding, Feng Shao
Growing a gasdermin pore in membranes of pyroptotic cells. The EMBO journal 37 (15) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Feng Shao