Olaf G Wiest (Olaf Wiest)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 38

Top Topics

Machine Learning

Histone Deacetylase

Molecular Dynamics

Top Venues

The Journal of organic chemistry

Organic letters

Journal of the American Chemical Society

Chemical science

This page only lists publications with an associated author ORCID identifier.

Publications

Angus Keto, Taicheng Guo, Morgan Underdue, Thijs Stuyver, Connor W Coley, Xiangliang Zhang, Elizabeth H Krenske, Olaf G Wiest
Data-Efficient, Chemistry-Aware Machine Learning Predictions of Diels-Alder Reaction Outcomes. Journal of the American Chemical Society (2024)
Olaf G Wiest, Christoph Alexander Bauer, Paul Helquist, Per-Ola Norrby, Samuel Genheden
Finding Relevant Retrosynthetic Disconnections for Stereocontrolled Reactions. Journal of chemical information and modeling (2024)
Olaf G Wiest, Christoph Alexander Bauer, Paul Helquist, Per-Ola Norrby, Samuel Genheden
Finding Relevant Retrosynthetic Disconnections for Stereocontrolled Reactions. Journal of chemical information and modeling 64 (15) (2024)
Angus Keto, Taicheng Guo, Morgan Underdue, Thijs Stuyver, Connor W Coley, Xiangliang Zhang, Elizabeth H Krenske, Olaf G Wiest
Data-Efficient, Chemistry-Aware Machine Learning Predictions of Diels-Alder Reaction Outcomes. Journal of the American Chemical Society 146 (23) (2024)
Michael P Maloney, Connor W Coley, Samuel Genheden, Nessa Carson, Paul Helquist, Per-Ola Norrby, Olaf G Wiest
Negative Data in Data Sets for Machine Learning Training. Organic letters 25 (17) (2023)
Michael P Maloney, Connor W Coley, Samuel Genheden, Nessa Carson, Paul Helquist, Per-Ola Norrby, Olaf G Wiest
Negative Data in Data Sets for Machine Learning Training. Organic letters (2023)
Michael P Maloney, Connor W Coley, Samuel Genheden, Nessa Carson, Paul Helquist, Per-Ola Norrby, Olaf G Wiest
Negative Data in Data Sets for Machine Learning Training. The Journal of organic chemistry 88 (9) (2023)
Michael P Maloney, Connor W Coley, Samuel Genheden, Nessa Carson, Paul Helquist, Per-Ola Norrby, Olaf G Wiest
Negative Data in Data Sets for Machine Learning Training. Organic letters 25 (17) (2023)
Yini Zhu, Yun Zhao, Jiling Wen, Sheng Liu, Tianhe Huang, Ishita Hatial, Xiaoxia Peng, Hawraa Al Janabi, Gang Huang, Jackson Mittlesteadt, Michael Cheng, Atul Bhardwaj, Brandon L Ashfeld, Kenneth R Kao, Dean Y Maeda, Xing Dai, Olaf G Wiest, Brian S J Blagg, Xuemin Lu, Liang Cheng, Jun Wan, Xin Lu
Targeting the chromatin effector Pygo2 promotes cytotoxic T cell responses and overcomes immunotherapy resistance in prostate cancer. Science immunology 8 (81) (2023)
Yini Zhu, Yun Zhao, Jiling Wen, Sheng Liu, Tianhe Huang, Ishita Hatial, Xiaoxia Peng, Hawraa Al Janabi, Gang Huang, Jackson Mittlesteadt, Michael Cheng, Atul Bhardwaj, Brandon L Ashfeld, Kenneth R Kao, Dean Y Maeda, Xing Dai, Olaf G Wiest, Brian S J Blagg, Xuemin Lu, Liang Cheng, Jun Wan, Xin Lu
Targeting the chromatin effector Pygo2 promotes cytotoxic T cell responses and overcomes immunotherapy resistance in prostate cancer. Science immunology 8 (81) (2023)
Yogesh B Narkhede, Atul Bhardwaj, Balindile B Motsa, Roopashi Saxena, Tej Sharma, Prem P Chapagain, Robert V Stahelin, Olaf G Wiest
Elucidating Residue-Level Determinants Affecting Dimerization of Ebola Virus Matrix Protein Using High-Throughput Site Saturation Mutagenesis and Biophysical Approaches. The journal of physical chemistry. B (2023)
Emily P Bacher, Raïssa Twiringiyimana, Kevin X Rodriguez, Renita A Wilson, Alexandra K Bodnar, Ryan O'Connell, Tiffany A Toni, Kaitlyn E Eckert, Olaf G Wiest, Brandon L Ashfeld
A Proline-Squaraine Ligand Framework (Pro-SqEB) for Stereoselective Rhodium(II)-Catalyzed Cyclopropanations. Organic letters (2023)
Himani N Patel, Brandon E Haines, Cynthia V Stauffacher, Paul Helquist, Olaf G Wiest
Computational Study of Base-Catalyzed Thiohemiacetal Decomposition in Pseudomonas mevalonii HMG-CoA Reductase. The journal of physical chemistry. B (2023)
Yini Zhu, Yun Zhao, Jiling Wen, Sheng Liu, Tianhe Huang, Ishita Hatial, Xiaoxia Peng, Hawraa Al Janabi, Gang Huang, Jackson Mittlesteadt, Michael Cheng, Atul Bhardwaj, Brandon L Ashfeld, Kenneth R Kao, Dean Y Maeda, Xing Dai, Olaf G Wiest, Brian S J Blagg, Xuemin Lu, Liang Cheng, Jun Wan, Xin Lu
Targeting the chromatin effector Pygo2 promotes cytotoxic T cell responses and overcomes immunotherapy resistance in prostate cancer. Science immunology 8 (81) (2023)
Yini Zhu, Yun Zhao, Jiling Wen, Sheng Liu, Tianhe Huang, Ishita Hatial, Xiaoxia Peng, Hawraa Al Janabi, Gang Huang, Jackson Mittlesteadt, Michael Cheng, Atul Bhardwaj, Brandon L Ashfeld, Kenneth R Kao, Dean Y Maeda, Xing Dai, Olaf G Wiest, Brian S J Blagg, Xuemin Lu, Liang Cheng, Jun Wan, Xin Lu
Targeting the chromatin effector Pygo2 promotes cytotoxic T cell responses and overcomes immunotherapy resistance in prostate cancer. Science immunology 8 (81) (2023)
Mandana Saebi, Bozhao Nan, John E Herr, Jessica Wahlers, Zhichun Guo, Andrzej M Zurański, Thierry Kogej, Per-Ola Norrby, Abigail G Doyle, Nitesh V Chawla, Olaf G Wiest
On the use of real-world datasets for reaction yield prediction. Chemical science 14 (19) (2023)
Michael P Maloney, Connor W Coley, Samuel Genheden, Nessa Carson, Paul Helquist, Per-Ola Norrby, Olaf G Wiest
Negative Data in Data Sets for Machine Learning Training. The Journal of organic chemistry (2023)
Michael P Maloney, Connor W Coley, Samuel Genheden, Nessa Carson, Paul Helquist, Per-Ola Norrby, Olaf G Wiest
Negative Data in Data Sets for Machine Learning Training. The Journal of organic chemistry 88 (9) (2023)
Mandana Saebi, Bozhao Nan, John E Herr, Jessica Wahlers, Zhichun Guo, Andrzej M Zurański, Thierry Kogej, Per-Ola Norrby, Abigail G Doyle, Nitesh V Chawla, Olaf G Wiest
On the use of real-world datasets for reaction yield prediction. Chemical science 14 (19) (2023)
Mandana Saebi, Bozhao Nan, John E Herr, Jessica Wahlers, Zhichun Guo, Andrzej M Zurański, Thierry Kogej, Per-Ola Norrby, Abigail G Doyle, Nitesh V Chawla, Olaf G Wiest
On the use of real-world datasets for reaction yield prediction. Chemical science 14 (19) (2023)
Francisco J Huizar, Harrison M Hill, Emily P Bacher, Kaitlyn E Eckert, Eva M Gulotty, Kevin X Rodriguez, Zachary D Tucker, Monimoy Banerjee, Haining Liu, Olaf G Wiest, Jeremiah J Zartman, Brandon L Ashfeld
Rational Design and Identification of Harmine-Inspired, N-Heterocyclic DYRK1A Inhibitors Employing a Functional Genomic In Vivo Drosophila Model System. ChemMedChem 17 (4) (2022)
Jessica Wahlers, Anthony R Rosales, Neil Berkel, Aaron Forbes, Paul Helquist, Per-Ola Norrby, Olaf G Wiest
A Quantum-Guided Molecular Mechanics Force Field for the Ferrocene Scaffold. The Journal of organic chemistry 87 (18) (2022)
Taylor R Quinn, Himani N Patel, Kevin H Koh, Brandon E Haines, Per-Ola Norrby, Paul Helquist, Olaf G Wiest
Automated fitting of transition state force fields for biomolecular simulations. PloS one 17 (3) (2022)
Emily P Bacher, Kevin J Koh, Antonio J Lepore, Allen G Oliver, Olaf G Wiest, Brandon L Ashfeld
A Phosphine-Mediated Dearomative Skeletal Rearrangement of Dianiline Squaraine Dyes. Organic letters 23 (8) (2021)
Jessica Wahlers, Jèssica Margalef, Eric Hansen, Armita Bayesteh, Paul Helquist, Montserrat Diéguez, Oscar Pamiès, Olaf G Wiest, Per-Ola Norrby
Proofreading experimentally assigned stereochemistry through Q2MM predictions in Pd-catalyzed allylic aminations. Nature communications 12 (1) (2021)
Adam D Durbin, Tingjian Wang, Virangika K Wimalasena, Mark W Zimmerman, Deyao Li, Neekesh V Dharia, Luca Mariani, Noha A M Shendy, Stephanie Nance, Anand G Patel, Ying Shao, Maya Mundada, Lily Maxham, Paul M C Park, Logan H Sigua, Ken Morita, Amy Saur Conway, Amanda L Robichaud, Antonio R Perez-Atayde, Melissa J Bikowitz, Taylor R Quinn, Olaf G Wiest, John Easton, Ernst Schonbrunn, Martha L Bulyk, Brian J Abraham, Kimberly Stegmaier, A Thomas Look, Jun Qi
EP300 selectively controls the enhancer landscape of MYCN-amplified neuroblastoma. Cancer discovery (2021)
Jessica Wahlers, Michael Maloney, Farbod Salahi, Anthony R Rosales, Paul Helquist, Per-Ola Norrby, Olaf G Wiest
Stereoselectivity Predictions for the Pd-Catalyzed 1,4-Conjugate Addition Using Quantum-Guided Molecular Mechanics. The Journal of organic chemistry 86 (8) (2021)
Dana L Cruz, Nina Pipalia, Shu Mao, Deepti Gadi, Gang Liu, Michael Grigalunas, Matthew O'Neill, Taylor R Quinn, Andi Kipper, Andreas Ekebergh, Alexander Dimmling, Carlos Gartner, Bruce J Melancon, Florence F Wagner, Edward Holson, Paul Helquist, Olaf G Wiest, Frederick R Maxfield
Inhibition of Histone Deacetylases 1, 2, and 3 Enhances Clearance of Cholesterol Accumulation in Niemann-Pick C1 Fibroblasts. ACS pharmacology & translational science 4 (3) (2021)
Taylor R Quinn, C Nicklaus Steussy, Brandon E Haines, Jinping Lei, Wei Wang, Fu Kit Sheong, Cynthia V Stauffacher, Xuhui Huang, Per-Ola Norrby, Paul Helquist, Olaf G Wiest
Microsecond timescale MD simulations at the transition state of PmHMGR predict remote allosteric residues. Chemical science 12 (18) (2021)
Anthony R Rosales, Sean P Ross, Paul Helquist, Per-Ola Norrby, Matthew S Sigman, Olaf G Wiest
Transition State Force Field for the Asymmetric Redox-Relay Heck Reaction. Journal of the American Chemical Society 142 (21) (2020)
Emily M Work, Guillermo Ferraudi, Luke Kiefer, Gang Liu, Michael Grigalunas, Atul Bhardwaj, Rasmin Kaur, Janel M Dempsey, Daniel Wüstner, Paul Helquist, Olaf G Wiest
Design, Synthesis, and Evaluation of a Luminescent Cholesterol Mimic. The Journal of organic chemistry 86 (2) (2020)
Diane N Le, Eric Hansen, Hasan A Khan, Byoungmoo Kim, Olaf G Wiest, Vy M Dong
Hydrogenation catalyst generates cyclic peptide stereocentres in sequence. Nature chemistry 10 (9) (2018)
Farbod Salahi, Vatsal Purohit, Guillermo Ferraudi, Cynthia Stauffacher, Olaf G Wiest, Paul Helquist
pHP-Tethered N-Acyl Carbamate: A Photocage for Nicotinamide. Organic letters 20 (9) (2018)
Xiaoxiao Zhang, Kai Chen, Yun-Dong Wu, Olaf G Wiest
Protein dynamics and structural waters in bromodomains. PloS one 12 (10) (2017)
Xiaoqiang Huang, Taylor R Quinn, Klaus Harms, Richard D Webster, Lilu Zhang, Olaf G Wiest, Eric Meggers
Direct Visible-Light-Excited Asymmetric Lewis Acid Catalysis of Intermolecular [2+2] Photocycloadditions. Journal of the American Chemical Society 139 (27) (2017)
Jiajia Ma, Anthony R Rosales, Xiaoqiang Huang, Klaus Harms, Radostan Riedel, Olaf G Wiest, Eric Meggers
Visible-Light-Activated Asymmetric β-C-H Functionalization of Acceptor-Substituted Ketones with 1,2-Dicarbonyl Compounds. Journal of the American Chemical Society 139 (48) (2017)
Brandon Tutkowski, Eric Meggers, Olaf G Wiest
Understanding Rate Acceleration and Stereoinduction of an Asymmetric Giese Reaction Mediated by a Chiral Rhodium Catalyst. Journal of the American Chemical Society 139 (24) (2017)
Joshua L Brooks, Liping Xu, Olaf G Wiest, Derek S Tan
Diastereoselective Synthesis of Highly Substituted Tetrahydrofurans by Pd-Catalyzed Tandem Oxidative Cyclization-Redox Relay Reactions Controlled by Intramolecular Hydrogen Bonding. The Journal of organic chemistry 82 (1) (2016)