Brian J Abraham

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 29

Top Topics

Transcription Factor

Gene Expression

Acute Lymphoblastic Leukemia

Genome Wide Association

Top Venues

Science (New York, N.Y.)

Nature communications

Science advances

Nature genetics

This page only lists publications with an associated author ORCID identifier.

Publications

Noha A M Shendy, Melissa Bikowitz, Logan H Sigua, Yang Zhang, Audrey Mercier, Yousef Khashana, Stephanie Nance, Qi Liu, Ian M Delahunty, Sarah Robinson, Vanshita Goel, Matthew G Rees, Melissa A Ronan, Tingjian Wang, Mustafa Kocak, Jennifer A Roth, Yingzhe Wang, Burgess B Freeman, Brent A Orr, Brian J Abraham, Martine F Roussel, Ernst K Schonbrunn, Jun Qi, Adam D Durbin
Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition. Nature communications 15 (1) (2024)
Noha A M Shendy, Melissa Bikowitz, Logan H Sigua, Yang Zhang, Audrey Mercier, Yousef Khashana, Stephanie Nance, Qi Liu, Ian M Delahunty, Sarah Robinson, Vanshita Goel, Matthew G Rees, Melissa A Ronan, Tingjian Wang, Mustafa Kocak, Jennifer A Roth, Yingzhe Wang, Burgess B Freeman, Brent A Orr, Brian J Abraham, Martine F Roussel, Ernst K Schonbrunn, Jun Qi, Adam D Durbin
Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition. Nature communications 15 (1) (2024)
Noha A M Shendy, Melissa Bikowitz, Logan H Sigua, Yang Zhang, Audrey Mercier, Yousef Khashana, Stephanie Nance, Qi Liu, Ian M Delahunty, Sarah Robinson, Vanshita Goel, Matthew G Rees, Melissa A Ronan, Tingjian Wang, Mustafa Kocak, Jennifer A Roth, Yingzhe Wang, Burgess B Freeman, Brent A Orr, Brian J Abraham, Martine F Roussel, Ernst K Schonbrunn, Jun Qi, Adam D Durbin
Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition. Nature communications 15 (1) (2024)
Noha A M Shendy, Melissa Bikowitz, Logan H Sigua, Yang Zhang, Audrey Mercier, Yousef Khashana, Stephanie Nance, Qi Liu, Ian M Delahunty, Sarah Robinson, Vanshita Goel, Matthew G Rees, Melissa A Ronan, Tingjian Wang, Mustafa Kocak, Jennifer A Roth, Yingzhe Wang, Burgess B Freeman, Brent A Orr, Brian J Abraham, Martine F Roussel, Ernst K Schonbrunn, Jun Qi, Adam D Durbin
Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition. Nature communications 15 (1) (2024)
Noha A M Shendy, Melissa Bikowitz, Logan H Sigua, Yang Zhang, Audrey Mercier, Yousef Khashana, Stephanie Nance, Qi Liu, Ian M Delahunty, Sarah Robinson, Vanshita Goel, Matthew G Rees, Melissa A Ronan, Tingjian Wang, Mustafa Kocak, Jennifer A Roth, Yingzhe Wang, Burgess B Freeman, Brent A Orr, Brian J Abraham, Martine F Roussel, Ernst K Schonbrunn, Jun Qi, Adam D Durbin
Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition. Nature communications 15 (1) (2024)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Madeline B Searcy, Randolph K Larsen, Bradley T Stevens, Yang Zhang, Hongjian Jin, Catherine J Drummond, Casey G Langdon, Katherine E Gadek, Kyna Vuong, Kristin B Reed, Matthew R Garcia, Bei-Si Xu, Darden W Kimbrough, Grace E Adkins, Mohamed Nadhir Djekidel, Shaina N Porter, Patrick A Schreiner, Shondra M Pruett-Miller, Brian J Abraham, Jerold E Rehg, Mark E Hatley
PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors. Nature communications 14 (1) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Modupeore O Adetunji, Brian J Abraham
SEAseq: a portable and cloud-based chromatin occupancy analysis suite. BMC bioinformatics 23 (1) (2022)
Marlies P Rossmann, Karen Hoi, Victoria Chan, Brian J Abraham, Song Yang, James P Mullahoo, Malvina Papanastasiou, Ying Wang, Ilaria Elia, Julie R Perlin, Elliott J Hagedorn, Sara Hetzel, Raha Weigert, Sejal Vyas, Partha P Nag, Lucas B Sullivan, Curtis R Warren, Bilguujin Dorjsuren, Eugenia Custo Greig, Isaac Adatto, Chad A Cowan, Stuart L Schreiber, Richard A Young, Alexander Meissner, Marcia C Haigis, Siegfried Hekimi, Steven A Carr, Leonard I Zon
Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis. Science (New York, N.Y.) 372 (6543) (2021)
Mark W Zimmerman, Adam D Durbin, Shuning He, Felix Oppel, Hui Shi, Ting Tao, Zhaodong Li, Alla Berezovskaya, Yu Liu, Jinghui Zhang, Richard A Young, Brian J Abraham, A Thomas Look
Retinoic acid rewires the adrenergic core regulatory circuitry of childhood neuroblastoma. Science advances 7 (43) (2021)
Adam D Durbin, Tingjian Wang, Virangika K Wimalasena, Mark W Zimmerman, Deyao Li, Neekesh V Dharia, Luca Mariani, Noha A M Shendy, Stephanie Nance, Anand G Patel, Ying Shao, Maya Mundada, Lily Maxham, Paul M C Park, Logan H Sigua, Ken Morita, Amy Saur Conway, Amanda L Robichaud, Antonio R Perez-Atayde, Melissa J Bikowitz, Taylor R Quinn, Olaf G Wiest, John Easton, Ernst Schonbrunn, Martha L Bulyk, Brian J Abraham, Kimberly Stegmaier, A Thomas Look, Jun Qi
EP300 selectively controls the enhancer landscape of MYCN-amplified neuroblastoma. Cancer discovery (2021)
Huan-Chang Liang, Mariantonia Costanza, Nicole Prutsch, Mark W Zimmerman, Elisabeth Gurnhofer, Ivonne-Aidee Montes-Mojarro, Brian J Abraham, Nina Prokoph, Stefan Stoiber, Simone Tangermann, Cosimo Lobello, Jan Oppelt, Ioannis Anagnostopoulos, Thomas Hielscher, Shahid Pervez, Wolfram Klapper, Francesca Zammarchi, Daniel Adriano Silva, K Christopher Garcia, Julien S Baker, Martin Janz, Nikolai Schleussner, Falko Fend, Šárka Pospíšilová, Andrea Janiková, Jacqueline Wallwitz, Dagmar Stoiber, Ingrid Simonitsch-Klupp, Lorenzo Cerroni, Stefano Pileri, Laurence L de Leval, David Sibon, Virginie Fataccioli, Philippe Gaulard, Chalid Assaf, Fabian Knörr, Christine Damm-Welk, Wilhelm Woessmann, Suzanne D Turner, A Thomas Look, Stephan Mathas, Lukas Kenner, Olaf Merkel
Super-enhancer-based identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic large cell lymphoma. Nature communications 12 (1) (2021)
Jessica Reddy, Marcos A S Fonseca, Rosario I Corona, Robbin Nameki, Felipe Segato Dezem, Isaac A Klein, Heidi Chang, Daniele Chaves-Moreira, Lena K Afeyan, Tathiane Maistro Malta, Xianzhi Lin, Forough Abbasi, Alba Font-Tello, Thais S Sabedot, Paloma Cejas, Norma Rodríguez-Malavé, Ji-Heui Seo, De-Chen Lin, Ursula Matulonis, Beth Y Karlan, Simon A Gayther, Bogdan Pasaniuc, Alexander Gusev, Houtan Noushmehr, Henry W Long, Matthew L Freedman, Ronny Drapkin, Richard A Young, Brian J Abraham, Kate Lawrenson
Predicting master transcription factors from pan-cancer expression data. Science advances 7 (48) (2021)
Ting Tao, Hui Shi, Luca Mariani, Brian J Abraham, Adam D Durbin, Mark W Zimmerman, John T Powers, Pavlos Missios, Kenneth N Ross, Antonio R Perez-Atayde, Martha L Bulyk, Richard A Young, George Q Daley, A Thomas Look
LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors. Proceedings of the National Academy of Sciences of the United States of America 117 (28) (2020)
Hui Shi, Ting Tao, Brian J Abraham, Adam D Durbin, Mark W Zimmerman, Cigall Kadoch, A Thomas Look
ARID1A loss in neuroblastoma promotes the adrenergic-to-mesenchymal transition by regulating enhancer-mediated gene expression. Science advances 6 (29) (2020)
Avik Choudhuri, Eirini Trompouki, Brian J Abraham, Leandro M Colli, Kian Hong Kock, William Mallard, Min-Lee Yang, Divya S Vinjamur, Alireza Ghamari, Audrey Sporrij, Karen Hoi, Barbara Hummel, Sonja Boatman, Victoria Chan, Sierra Tseng, Satish K Nandakumar, Song Yang, Asher Lichtig, Michael Superdock, Seraj N Grimes, Teresa V Bowman, Yi Zhou, Shinichiro Takahashi, Roby Joehanes, Alan B Cantor, Daniel E Bauer, Santhi K Ganesh, John Rinn, Paul S Albert, Martha L Bulyk, Stephen J Chanock, Richard A Young, Leonard I Zon
Common variants in signaling transcription-factor-binding sites drive phenotypic variability in red blood cell traits. Nature genetics 52 (12) (2020)
Cristina Santoriello, Audrey Sporrij, Song Yang, Ryan A Flynn, Telmo Henriques, Bilguujin Dorjsuren, Eugenia Custo Greig, Wyatt McCall, Meredith E Stanhope, Maurizio Fazio, Michael Superdock, Asher Lichtig, Isaac Adatto, Brian J Abraham, Marian Kalocsay, Michael Jurynec, Yi Zhou, Karen Adelman, Eliezer Calo, Leonard I Zon
RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells. Nature cell biology 22 (4) (2020)
Lu Wang, Tze King Tan, Adam D Durbin, Mark W Zimmerman, Brian J Abraham, Shi Hao Tan, Phuong Cao Thi Ngoc, Nina Weichert-Leahey, Koshi Akahane, Lee N Lawton, Jo Lynne Rokita, John M Maris, Richard A Young, A Thomas Look, Takaomi Sanda
ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry. Nature communications 10 (1) (2019)
Adam D Durbin, Mark W Zimmerman, Neekesh V Dharia, Brian J Abraham, Amanda Balboni Iniguez, Nina Weichert-Leahey, Shuning He, John M Krill-Burger, David E Root, Francisca Vazquez, Aviad Tsherniak, William C Hahn, Todd R Golub, Richard A Young, A Thomas Look, Kimberly Stegmaier
Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry. Nature genetics 50 (9) (2018)
Benjamin R Sabari, Alessandra Dall'Agnese, Ann Boija, Isaac A Klein, Eliot L Coffey, Krishna Shrinivas, Brian J Abraham, Nancy M Hannett, Alicia V Zamudio, John C Manteiga, Charles H Li, Yang E Guo, Daniel S Day, Jurian Schuijers, Eliza Vasile, Sohail Malik, Denes Hnisz, Tong Ihn Lee, Ibrahim I Cisse, Robert G Roeder, Phillip A Sharp, Arup K Chakraborty, Richard A Young
Coactivator condensation at super-enhancers links phase separation and gene control. Science (New York, N.Y.) 361 (6400) (2018)
Rudi Micheletti, Isabelle Plaisance, Brian J Abraham, Alexandre Sarre, Ching-Chia Ting, Michael Alexanian, Daniel Maric, Damien Maison, Mohamed Nemir, Richard A Young, Blanche Schroen, Arantxa González, Samir Ounzain, Thierry Pedrazzini
The long noncoding RNA Wisper controls cardiac fibrosis and remodeling. Science translational medicine 9 (395) (2018)
Marc R Mansour, Shuning He, Zhaodong Li, Riadh Lobbardi, Brian J Abraham, Clemens Hug, Sunniyat Rahman, Theresa E León, You-Yi Kuang, Mark W Zimmerman, Traci M Blonquist, Evisa Gjini, Alejandro Gutierrez, Qin Tang, Laura Garcia-Perez, Karin Pike-Overzet, Lars Anders, Alla Berezovskaya, Yi Zhou, Leonard I Zon, Donna S Neuberg, Adele K Fielding, Frank J T Staal, David M Langenau, Takaomi Sanda, Richard A Young, A Thomas Look
JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia. The Journal of experimental medicine 215 (7) (2018)