Paul W R Harris (P W R Harris)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 32

Top Topics

Structure Activity Relationship

Top Venues

Organic & biomolecular chemistry

Chemical science

Journal of natural products

Chemistry (Weinheim an der Bergstrasse, Germany)

This page only lists publications with an associated author ORCID identifier.

Publications

Dennise Palpal-Latoc, Aimee J Horsfall, Alan J Cameron, Georgia Campbell, Scott A Ferguson, Gregory M Cook, Veronika Sander, Alan J Davidson, Paul W R Harris, Margaret A Brimble
Synthesis, Structure-Activity Relationship Study, Bioactivity, and Nephrotoxicity Evaluation of the Proposed Structure of the Cyclic Lipodepsipeptide Brevicidine B. Journal of natural products (2024)
Dennise Palpal-Latoc, Aimee J Horsfall, Alan J Cameron, Georgia Campbell, Scott A Ferguson, Gregory M Cook, Veronika Sander, Alan J Davidson, Paul W R Harris, Margaret A Brimble
Synthesis, Structure-Activity Relationship Study, Bioactivity, and Nephrotoxicity Evaluation of the Proposed Structure of the Cyclic Lipodepsipeptide Brevicidine B. Journal of natural products 87 (4) (2024)
Andrew Siow, Renata Kowalczyk, Jiwon Hong, Paul W R Harris
Chemical Modifications on the αvβ6 Integrin Targeting A20FMDV2 Peptide: A Review. ChemMedChem (2024)
Dennise Palpal-Latoc, Aimee J Horsfall, Alan J Cameron, Georgia Campbell, Scott A Ferguson, Gregory M Cook, Veronika Sander, Alan J Davidson, Paul W R Harris, Margaret A Brimble
Synthesis, Structure-Activity Relationship Study, Bioactivity, and Nephrotoxicity Evaluation of the Proposed Structure of the Cyclic Lipodepsipeptide Brevicidine B. Journal of natural products 87 (4) (2024)
Andrew Siow, Paul W R Harris
Leveraging the Mukaiyama oxidation-reduction condensation reaction for on-resin aryl thio-esterification for bio-conjugation. Organic & biomolecular chemistry (2024)
Elena Harjes, Patrick J B Edwards, Sean W Bisset, Mark L Patchett, Geoffrey B Jameson, Sung-Hyun Yang, Claudio D Navo, Paul W R Harris, Margaret A Brimble, Gillian E Norris
NMR Shows Why a Small Chemical Change Almost Abolishes the Antimicrobial Activity of Glycocin F. Biochemistry (2023)
Saawan Kumar, Mie Riisom, Stephen M F Jamieson, Iman Kavianinia, Paul W R Harris, Nils Metzler Nolte, Margaret A Brimble, Christian G Hartinger
On-Resin Conjugation of the Ruthenium Anticancer Agent Plecstatin-1 to Peptide Vectors. Inorganic chemistry (2023)
Dennise Palpal-Latoc, Margaret A Brimble, Paul W R Harris, Aimee J Horsfall
Factors influencing on-resin depsipeptide bond formation: case studies on daptomycin- and brevicidine-derived sequences. Organic & biomolecular chemistry (2023)
Clouie Justin Aguilar, Makhdoom Sarwar, Sujay Prabakar, Wenkai Zhang, Paul W R Harris, Margaret A Brimble, Iman Kavianinia
Harnessing the power of a photoinitiated thiol-ene "click" reaction for the efficient synthesis of S -lipidated collagen model peptide amphiphiles. Organic & biomolecular chemistry (2023)
Tyla I Alexander, Zoe Tasma, Andrew Siow, Tayla A Rees, Margaret A Brimble, Paul W R Harris, Debbie L Hay, Christopher S Walker
Novel Fluorescently Labeled PACAP and VIP Highlight Differences between Peptide Internalization and Receptor Pharmacology. ACS pharmacology & translational science 6 (1) (2022)
Shengping Zhang, Luis M De Leon Rodriguez, Freda F Li, Renjie Huang, Ivanhoe K H Leung, Paul W R Harris, Margaret A Brimble
A novel tyrosine hyperoxidation enables selective peptide cleavage. Chemical science 13 (9) (2022)
Nadiia Kovalenko, Jonathan A Swain, Georgina K Howard, Yann O Hermant, Alan J Cameron, Louise A Stubbing, Paul W R Harris, Margaret A Brimble
Synthetic Studies towards the Calcium-Dependent Lipopeptide Antibiotic Cadaside B. Chemistry (Weinheim an der Bergstrasse, Germany) (2022)
Tyla I Alexander, Zoe Tasma, Andrew Siow, Tayla A Rees, Margaret A Brimble, Paul W R Harris, Debbie L Hay, Christopher S Walker
Novel Fluorescently Labeled PACAP and VIP Highlight Differences between Peptide Internalization and Receptor Pharmacology. ACS pharmacology & translational science 6 (1) (2022)
Dianna Truong, Nelson Y S Lam, Meder Kamalov, Mie Riisom, Stephen M F Jamieson, Paul W R Harris, Margaret A Brimble, Nils Metzler Nolte, Christian G Hartinger
A Solid Support-Based Synthetic Strategy for the Site-Selective Functionalization of Peptides with Organometallic Half-Sandwich Moieties. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (12) (2022)
Paul W R Harris, Andrew Siow, Sung-Hyun Yang, Andrew D Wadsworth, Lyndia Tan, Yann Hermant, Yubing Mao, Chalice An, Cameron C Hanna, Alan J Cameron, Jane R Allison, Aparajita Chakraborty, Scott A Ferguson, Sonya Mros, Kiel Hards, Gregory M Cook, Deborah A Williamson, Glen P Carter, Susanna T S Chan, Gavin A Painter, Veronika Sander, Alan J Davidson, Margaret A Brimble
Synthesis, Antibacterial Activity, and Nephrotoxicity of Polymyxin B Analogues Modified at Leu-7, d-Phe-6, and the N-Terminus Enabled by S-Lipidation. ACS infectious diseases (2022)
Zoe Tasma, Andrew Siow, Paul W R Harris, Margaret A Brimble, Debbie L Hay, Christopher S Walker
Characterisation of agonist signalling profiles and agonist-dependent antagonism at PACAP-responsive receptors: Implications for drug discovery. British journal of pharmacology (2021)
Cameron C Hanna, Yann O Hermant, Paul W R Harris, Margaret A Brimble
Discovery, Synthesis, and Optimization of Peptide-Based Antibiotics. Accounts of chemical research 54 (8) (2021)
Yann Hermant, Dennise Palpal-Latoc, Nadiia Kovalenko, Alan J Cameron, Margaret A Brimble, Paul W R Harris
The Total Chemical Synthesis and Biological Evaluation of the Cationic Antimicrobial Peptides, Laterocidine and Brevicidine. Journal of natural products 84 (8) (2021)
Emily S Grant-Mackie, Elyse T Williams, Paul W R Harris, Margaret A Brimble
Aminovinyl Cysteine Containing Peptides: A Unique Motif That Imparts Key Biological Activity. JACS Au 1 (10) (2021)
Yuxin Wang, Sung H Yang, Margaret A Brimble, Paul W R Harris
Recent Progress in the Synthesis of Homogeneous Erythropoietin (EPO) Glycoforms. Chembiochem : a European journal of chemical biology 21 (23) (2020)
Victor V Yim, Iman Kavianinia, Alan J Cameron, Paul W R Harris, Margaret A Brimble
Direct synthesis of cyclic lipopeptides using intramolecular native chemical ligation and thiol-ene CLipPA chemistry. Organic & biomolecular chemistry 18 (15) (2020)
Juliana T W Tong, Iman Kavianinia, Scott A Ferguson, Gregory M Cook, Paul W R Harris, Margaret A Brimble
Synthesis of paenipeptin C' analogues employing solution-phase CLipPA chemistry. Organic & biomolecular chemistry (2020)
Victor V Yim, Iman Kavianinia, Melanie K Knottenbelt, Scott A Ferguson, Gregory M Cook, Simon Swift, Aparajita Chakraborty, Jane R Allison, Alan J Cameron, Paul W R Harris, Margaret A Brimble
"CLipP"ing on lipids to generate antibacterial lipopeptides. Chemical science 11 (22) (2020)
Alan J Cameron, Paul W R Harris, Margaret A Brimble
On-Resin Preparation of Allenamidyl Peptides: A Versatile Chemoselective Conjugation and Intramolecular Cyclisation Tool. Angewandte Chemie (International ed. in English) 59 (41) (2020)
Sung-Hyun Yang, Connor A Clemett, Margaret A Brimble, Simon J O'Carroll, Paul W R Harris
Synthesis and biological evaluation of S-lipidated lipopeptides of a connexin 43 channel inhibitory peptide. RSC medicinal chemistry 11 (9) (2020)
Buzhe Xu, Yann Hermant, Sung-Hyun Yang, Paul W R Harris, Margaret A Brimble
A Versatile Boc Solid Phase Synthesis of Daptomycin and Analogues Using Site Specific, On-Resin Ozonolysis to Install the Kynurenine Residue. Chemistry (Weinheim an der Bergstrasse, Germany) 25 (62) (2019)
Shengping Zhang, Luis M De Leon Rodriguez, Renjie Huang, Ivanhoe K H Leung, Paul W R Harris, Margaret A Brimble
Total synthesis of the proposed structure of talarolide A. Organic & biomolecular chemistry 16 (29) (2019)
Johanes K Kasim, Iman Kavianinia, Jin Ng, Paul W R Harris, Nigel P Birch, Margaret A Brimble
Efficient synthesis and characterisation of the amyloid beta peptide, Aβ1-42, using a double linker system. Organic & biomolecular chemistry 17 (1) (2019)
Emma K Davison, Alan J Cameron, Paul W R Harris, Margaret A Brimble
Synthesis of endolides A and B: naturally occurring N-methylated cyclic tetrapeptides. MedChemComm 10 (5) (2019)
Zaid Amso, Sean W Bisset, Sung-Hyun Yang, Paul W R Harris, Tom H Wright, Claudio D Navo, Mark L Patchett, Gillian E Norris, Margaret A Brimble
Total chemical synthesis of glycocin F and analogues: S-glycosylation confers improved antimicrobial activity. Chemical science 9 (6) (2018)
Buzhe Xu, Emma J Aitken, Benjamin P Baker, Claire A Turner, Joanne E Harvey, Matthew B Stott, Jean F Power, Paul W R Harris, Joanne E Harvey, Margaret A Brimble
Genome mining, isolation, chemical synthesis and biological evaluation of a novel lanthipeptide, tikitericin, from the extremophilic microorganism Thermogemmatispora strain T81. Chemical science 9 (37) (2018)
D J Lee, Alan J Cameron, Tom H Wright, Paul W R Harris, Margaret A Brimble
A synthetic approach to 'click' neoglycoprotein analogues of EPO employing one-pot native chemical ligation and CuAAC chemistry. Chemical science 10 (3) (2018)