Akane Kawamura

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 38

Top Venues

Journal of medicinal chemistry

Scientific reports

FEBS letters

Cancers

Newcastle University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Newcastle University Oct 01 2019

United Kingdom

Professor of Chemical Biology :: School of Natural and Environmental Sciences

University of Oxford Feb 01 2019

United Kingdom

Associate Professor :: Department of Chemistry

University of Oxford Apr 01 2016 - Jan 31 2019

United Kingdom

University Research Lecturer :: Department of Chemistry

Publications

Roman Belle, Hilal Saraç, Eidarus Salah, Bhaskar Bhushan, Aleksandra Szykowska, Grace Roper, Anthony Tumber, Skirmantas Kriaucionis, Nicola Burgess-Brown, Christopher J Schofield, Tom Brown, Akane Kawamura
Focused Screening Identifies Different Sensitivities of Human TET Oxygenases to the Oncometabolite 2-Hydroxyglutarate. Journal of medicinal chemistry 67 (6) (2024)
Roman Belle, Hilal Saraç, Eidarus Salah, Bhaskar Bhushan, Aleksandra Szykowska, Grace Roper, Anthony Tumber, Skirmantas Kriaucionis, Nicola Burgess-Brown, Christopher J Schofield, Tom Brown, Akane Kawamura
Focused Screening Identifies Different Sensitivities of Human TET Oxygenases to the Oncometabolite 2-Hydroxyglutarate. Journal of medicinal chemistry 67 (6) (2024)
Roman Belle, Hilal Saraç, Eidarus Salah, Bhaskar Bhushan, Aleksandra Szykowska, Grace Roper, Anthony Tumber, Skirmantas Kriaucionis, Nicola Burgess-Brown, Christopher J Schofield, Tom Brown, Akane Kawamura
Focused Screening Identifies Different Sensitivities of Human TET Oxygenases to the Oncometabolite 2-Hydroxyglutarate. Journal of medicinal chemistry 67 (6) (2024)
Roman Belle, Hilal Saraç, Eidarus Salah, Bhaskar Bhushan, Aleksandra Szykowska, Grace Roper, Anthony Tumber, Skirmantas Kriaucionis, Nicola Burgess-Brown, Christopher J Schofield, Tom Brown, Akane Kawamura
Focused Screening Identifies Different Sensitivities of Human TET Oxygenases to the Oncometabolite 2-Hydroxyglutarate. Journal of medicinal chemistry (2024)
Roman Belle, Hilal Saraç, Eidarus Salah, Bhaskar Bhushan, Aleksandra Szykowska, Grace Roper, Anthony Tumber, Skirmantas Kriaucionis, Nicola Burgess-Brown, Christopher J Schofield, Tom Brown, Akane Kawamura
Focused Screening Identifies Different Sensitivities of Human TET Oxygenases to the Oncometabolite 2-Hydroxyglutarate. Journal of medicinal chemistry (2024)
Roman Belle, Hilal Saraç, Eidarus Salah, Bhaskar Bhushan, Aleksandra Szykowska, Grace Roper, Anthony Tumber, Skirmantas Kriaucionis, Nicola Burgess-Brown, Christopher J Schofield, Tom Brown, Akane Kawamura
Focused Screening Identifies Different Sensitivities of Human TET Oxygenases to the Oncometabolite 2-Hydroxyglutarate. Journal of medicinal chemistry 67 (6) (2024)
Roman Belle, Hilal Saraç, Eidarus Salah, Bhaskar Bhushan, Aleksandra Szykowska, Grace Roper, Anthony Tumber, Skirmantas Kriaucionis, Nicola Burgess-Brown, Christopher J Schofield, Tom Brown, Akane Kawamura
Focused Screening Identifies Different Sensitivities of Human TET Oxygenases to the Oncometabolite 2-Hydroxyglutarate. Journal of medicinal chemistry 67 (6) (2024)
Joanna Bonnici, Razanne Oueini, Eidarus Salah, Catrine Johansson, Christopher J Schofield, Akane Kawamura
The catalytic domains of all human KDM5 JmjC demethylases catalyse N-methyl arginine demethylation. FEBS letters (2023)
Thomas P Smith, Bhaskar Bhushan, Daniele Granata, Christian S Kaas, Birgitte Andersen, Klaas W Decoene, Qiansheng Ren, Haimo Liu, Xinping Qu, Yang Yang, Jia Pan, Quijia Chen, Martin Münzel, Akane Kawamura
Identification and engineering of potent cyclic peptides with selective or promiscuous binding through biochemical profiling and bioinformatic data analysis. RSC chemical biology 5 (1) (2023)
Oliver D Coleman, Jessica Macdonald, Ben Thomson, Jennifer A Ward, Christopher J Stubbs, Tom E McAllister, Shane Clark, Siddique Amin, Yimang Cao, Martine I Abboud, Yijia Zhang, Hitesh Sanganee, Kilian V M Huber, Timothy D W Claridge, Akane Kawamura
Cyclic peptides target the aromatic cage of a PHD-finger reader domain to modulate epigenetic protein function. Chemical science 14 (26) (2023)
Joanna Bonnici, Razanne Oueini, Eidarus Salah, Catrine Johansson, Christopher J Schofield, Akane Kawamura
The catalytic domains of all human KDM5 JmjC demethylases catalyse N-methyl arginine demethylation. FEBS letters (2023)
Thomas P Smith, Bhaskar Bhushan, Daniele Granata, Christian S Kaas, Birgitte Andersen, Klaas W Decoene, Qiansheng Ren, Haimo Liu, Xinping Qu, Yang Yang, Jia Pan, Quijia Chen, Martin Münzel, Akane Kawamura
Identification and engineering of potent cyclic peptides with selective or promiscuous binding through biochemical profiling and bioinformatic data analysis. RSC chemical biology 5 (1) (2023)
Takashi Miura, Tika R Malla, C David Owen, Anthony Tumber, Lennart Brewitz, Michael A McDonough, Eidarus Salah, Naohiro Terasaka, Takayuki Katoh, Petra Lukacik, Claire Strain-Damerell, Halina Mikolajek, Martin Austin Walsh, Akane Kawamura, Christopher J Schofield, Hiroaki Suga
In vitro selection of macrocyclic peptide inhibitors containing cyclic γ 2,4 -amino acids targeting the SARS-CoV-2 main protease. Nature chemistry (2023)
Stuart J Conway, Akane Kawamura, Tracey M Marr, Frances Platt, Angela J Russell
Increasing Diversity in Admissions to Postgraduate Study. Journal of medicinal chemistry 65 (8) (2022)
Toni A Pringle, Oliver Coleman, Akane Kawamura, James C Knight
The influence of degree of labelling upon cellular internalisation of antibody-cell penetrating peptide conjugates. RSC advances 12 (43) (2022)
Ipek Bulut, Adam Lee, Ceyda Acilan, Dusan Ruzic, Roman Belle, Akane Kawamura, Sheraz Gul, Katarina Nikolic, Arasu Ganesan, Ceyda Acilan
Dual LSD1 and HDAC6 Inhibition Induces Doxorubicin Sensitivity in Acute Myeloid Leukemia Cells. Cancers 14 (23) (2022)
Ipek Bulut, Adam Lee, Ceyda Acilan, Dusan Ruzic, Roman Belle, Akane Kawamura, Sheraz Gul, Katarina Nikolic, Arasu Ganesan, Ceyda Acilan
Dual LSD1 and HDAC6 Inhibition Induces Doxorubicin Sensitivity in Acute Myeloid Leukemia Cells. Cancers 14 (23) (2022)
Ipek Bulut, Adam Lee, Ceyda Acilan, Dusan Ruzic, Roman Belle, Akane Kawamura, Sheraz Gul, Katarina Nikolic, Arasu Ganesan, Ceyda Acilan
Dual LSD1 and HDAC6 Inhibition Induces Doxorubicin Sensitivity in Acute Myeloid Leukemia Cells. Cancers 14 (23) (2022)
Bhaskar Bhushan, Daniele Granata, Christian S Kaas, Marina A Kasimova, Qiansheng Ren, Christian N Cramer, Mark D White, Ann Maria K Hansen, Christian Fledelius, Gaetano Invernizzi, Kristine Deibler, Oliver D Coleman, Xin Zhao, Xinping Qu, Haimo Liu, Silvana S Zurmühl, Janos T Kodra, Akane Kawamura, Martin Münzel
An integrated platform approach enables discovery of potent, selective and ligand-competitive cyclic peptides targeting the GIP receptor. Chemical science 13 (11) (2022)
Radosław P Nowak, Anthony Tumber, Eline Hendrix, Mohammad Salik Zeya Ansari, Manuela Sabatino, Lorenzo Antonini, Regina Andrijes, Eidarus Salah, Nicola Mautone, Francesca Romana Pellegrini, Klemensas Simelis, Akane Kawamura, Catrine Johansson, Daniela Passeri, Roberto Pellicciari, Alessia Ciogli, Donatella Del Bufalo, Rino Ragno, Mathew L Coleman, Daniela Trisciuoglio, Antonello Mai, Udo Oppermann, Christopher J Schofield, Dante Rotili
First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53. Journal of medicinal chemistry 64 (23) (2021)
Kamayani Singh, Graham Davies, Yara Alenazi, James R O Eaton, Akane Kawamura, Shoumo Bhattacharya
Author Correction: Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Scientific reports 11 (1) (2021)
Raphael Reinbold, Tobias John, Paolo Spingardi, Akane Kawamura, Christopher J Schofield, Richard J Hopkinson
Metampicillin is a cyclic aminal produced by reaction of ampicillin with formaldehyde. Scientific reports 10 (1) (2020)
Kuo-Feng Hsu, Sarah E Wilkins, Richard J Hopkinson, Rok Sekirnik, Emily Flashman, Akane Kawamura, James S O McCullagh, Louise J Walport, Christopher J Schofield
Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications. Epigenetics 16 (1) (2020)
Brian Josephson, Charlie Fehl, Patrick G Isenegger, Simon Nadal, Tom H Wright, Adeline W J Poh, Ben J Bower, Andrew M Giltrap, Lifu Chen, Christopher Batchelor-McAuley, Grace Roper, Oluwatobi Arisa, Jeroen B I Sap, Akane Kawamura, Andrew J Baldwin, Shabaz Mohammad, Richard G Compton, Véronique Gouverneur, Benjamin G Davis
Light-driven post-translational installation of reactive protein side chains. Nature 585 (7826) (2020)
Raphael Reinbold, Tobias John, Paolo Spingardi, Akane Kawamura, Amber L Thompson, Christopher J Schofield, Richard J Hopkinson
Formaldehyde quantification using ampicillin is not selective. Scientific reports 9 (1) (2019)
Martin Roatsch, Inga Hoffmann, Martine I Abboud, Rebecca L Hancock, Hanna Tarhonskaya, Kuo-Feng Hsu, Sarah E Wilkins, Tzu-Lan Yeh, Kerstin Lippl, Kerstin Serrer, Isabelle Moneke, Theresa D Ahrens, Dina Robaa, Sandra Wenzler, Nicolas P F Barthes, Henriette Franz, Wolfgang Sippl, Silke Lassmann, Sven Diederichs, Erik Schleicher, Christopher J Schofield, Akane Kawamura, Roland Schüle, Manfred Jung
The Clinically Used Iron Chelator Deferasirox Is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases. ACS chemical biology 14 (8) (2019)
Joanna Bonnici, Anthony Tumber, Akane Kawamura, Christopher J Schofield
Inhibitors of both the N-methyl lysyl- and arginyl-demethylase activities of the JmjC oxygenases. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 373 (1748) (2019)
Hilal Saraç, Tunç Morova, Elisabete Pires, James McCullagh, Anıl Kaplan, Ahmet Cingöz, Tugba Bagcı-Önder, Tamer T Önder, Akane Kawamura, Nathan A Lack
Systematic characterization of chromatin modifying enzymes identifies KDM3B as a critical regulator in castration resistant prostate cancer. Oncogene 39 (10) (2019)
Martine I Abboud, Tom E McAllister, Ivanhoe K H Leung, Rasheduzzaman Chowdhury, Christian Jorgensen, Carmen Domene, Jasmin Mecinovic, Kerstin Lippl, Rebecca L Hancock, Richard J Hopkinson, Akane Kawamura, Timothy D W Claridge, Christopher J Schofield
2-Oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2. Chemical communications (Cambridge, England) 54 (25) (2018)
Yara Alenazi, Kamayani Singh, Graham Davies, James R O Eaton, Philip N D Elders, Akane Kawamura, Shoumo Bhattacharya
Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets. Scientific reports 8 (1) (2018)
Louise J Walport, Richard J Hopkinson, Rasheduzzaman Chowdhury, Yijia Zhang, Joanna Bonnici, Rachel Schiller, Akane Kawamura, Christopher J Schofield
Mechanistic and structural studies of KDM-catalysed demethylation of histone 1 isotype 4 at lysine 26. FEBS letters 592 (19) (2018)
Rebecca L Hancock, Martine I Abboud, Tristan J Smart, Emily Flashman, Akane Kawamura, Christopher J Schofield, Richard J Hopkinson
Lysine-241 Has a Role in Coupling 2OG Turnover with Substrate Oxidation During KDM4-Catalysed Histone Demethylation. Chembiochem : a European journal of chemical biology 19 (9) (2018)
Rebecca L Hancock, Norma Masson, Kate Dunne, Emily Flashman, Akane Kawamura
The Activity of JmjC Histone Lysine Demethylase KDM4A is Highly Sensitive to Oxygen Concentrations. ACS chemical biology 12 (4) (2017)
Philip A Gerken, Jamie R Wolstenhulme, Anthony Tumber, Stephanie B Hatch, Yijia Zhang, Susanne Müller, Shane A Chandler, Barbara Mair, Fengling Li, Sebastian M B Nijman, Rebecca Konietzny, Tamas Szommer, Clarence Yapp, Oleg Fedorov, Justin L P Benesch, Masoud Vedadi, Benedikt M Kessler, Akane Kawamura, Paul E Brennan, Martin D Smith
Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7. Angewandte Chemie (International ed. in English) 56 (49) (2017)
Tzu-Lan Yeh, Thomas M Leissing, Martine I Abboud, Cyrille C Thinnes, Onur Atasoylu, James P Holt-Martyn, Dong Zhang, Anthony Tumber, Kerstin Lippl, Christopher T Lohans, Ivanhoe K H Leung, Helen Morcrette, Ian J Clifton, Timothy D W Claridge, Akane Kawamura, Emily Flashman, Xin Lu, Peter J Ratcliffe, Rasheduzzaman Chowdhury, Christopher W Pugh, Christopher J Schofield
Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials. Chemical science 8 (11) (2017)
Akane Kawamura, Martin Münzel, Tatsuya Kojima, Clarence Yapp, Bhaskar Bhushan, Yuki Goto, Anthony Tumber, Takayuki Katoh, Oliver N F King, Toby Passioura, Louise J Walport, Stephanie B Hatch, Sarah K Madden, Susanne Müller, Paul E Brennan, Rasheduzzaman Chowdhury, Richard J Hopkinson, Hiroaki Suga, Christopher J Schofield
Highly selective inhibition of histone demethylases by de novo macrocyclic peptides. Nature communications 8 (2017)
Kamayani Singh, Graham Davies, Yara Alenazi, James R O Eaton, Akane Kawamura, Shoumo Bhattacharya
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Scientific reports 7 (1) (2017)
Grzegorz Dobrynin, Tom E McAllister, Katarzyna B Leszczynska, Shaliny Ramachandran, Adam J Krieg, Akane Kawamura, Ester M Hammond
KDM4A regulates HIF-1 levels through H3K9me3. Scientific reports 7 (1) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Akane Kawamura