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Christopher T Lohans (Christopher Lohans)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 16

Top Venues

Chemistry (Weinheim an der Bergstrasse, Germany)

Angewandte Chemie (International ed. in English)

Journal of medicinal chemistry

Antimicrobial agents and chemotherapy

Queen's University

University of Alberta (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Queen's University Aug 1o 2019

Canada

Assistant Professor :: Department of Biomedical and Molecular Sciences

Education History

University of Alberta Sep 1o 2009 - Oct 1o 2014

Canada

PHD :: Department of Chemistry

Publications

Mitchell A Jeffs, Rachel A V Gray, Prameet M Sheth, Christopher T Lohans
Development of a whole-cell biosensor for β-lactamase inhibitor discovery. Chemical communications (Cambridge, England) (2023)
Pauline A Lang, Ritu Raj, Anthony Tumber, Christopher T Lohans, Patrick Rabe, Carol V Robinson, Jürgen Brem, Christopher J Schofield
Studies on enmetazobactam clarify mechanisms of widely used β-lactamase inhibitors. Proceedings of the National Academy of Sciences of the United States of America 119 (18) (2022)
Mitchell A Jeffs, Christopher T Lohans
Inhibiting the metallo-β-lactamases: challenges and strategies to overcome bacterial β-lactam resistance. Future medicinal chemistry 14 (14) (2022)
Montserrat Mora-Ochomogo, Christopher T Lohans
β-Lactam antibiotic targets and resistance mechanisms: from covalent inhibitors to substrates. RSC medicinal chemistry 12 (10) (2021)
Faraz Shaikh, Yuguang Zhao, Luis Alvarez, Maria Iliopoulou, Christopher T Lohans, Christopher J Schofield, Sergi Padilla-Parra, Shirley Weng In Siu, Elizabeth E Fry, Jingshan Ren, David I Stuart
Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library. Journal of medicinal chemistry 62 (6) (2019)
Mariska de Munnik, Christopher T Lohans, Gareth W Langley, Corentin Bon, Jürgen Brem, Christopher J Schofield
A Fluorescence-Based Assay for Screening β-Lactams Targeting the Mycobacterium tuberculosis Transpeptidase LdtMt2. Chembiochem : a European journal of chemical biology 21 (3) (2019)
Patrick Rabe, Jos J A G Kamps, Christopher J Schofield, Christopher T Lohans
Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in β-lactam biosynthesis. Natural product reports 35 (8) (2019)
Faraz Shaikh, Yuguang Zhao, Luis Alvarez, Maria Iliopoulou, Christopher T Lohans, Christopher J Schofield, Sergi Padilla-Parra, Shirley W I Siu, Elizabeth E Fry, Jingshan Ren, David I Stuart
Correction to "Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library". Journal of medicinal chemistry 62 (21) (2019)
Cyrille C Thinnes, Christopher T Lohans, Martine I Abboud, Tzu-Lan Yeh, Anthony Tumber, Radosław P Nowak, Martin Attwood, Matthew E Cockman, Udo Oppermann, Christoph Loenarz, Christopher J Schofield
Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding. Chemistry (Weinheim an der Bergstrasse, Germany) 25 (8) (2019)
Christopher T Lohans, H T Henry Chan, Tika R Malla, Kiran Kumar, Jos J A G Kamps, Darius J B McArdle, Emma van Groesen, Mariska de Munnik, Catherine L Tooke, James Spencer, Robert S Paton, Jürgen Brem, Christopher J Schofield
Non-Hydrolytic β-Lactam Antibiotic Fragmentation by l,d-Transpeptidases and Serine β-Lactamase Cysteine Variants. Angewandte Chemie (International ed. in English) 58 (7) (2019)
Emma van Groesen, Christopher T Lohans, Jürgen Brem, Kristina M J Aertker, Timothy D W Claridge, Christopher J Schofield
19 F NMR Monitoring of Reversible Protein Post-Translational Modifications: Class D β-Lactamase Carbamylation and Inhibition. Chemistry (Weinheim an der Bergstrasse, Germany) 25 (51) (2019)
Christopher T Lohans, Emma van Groesen, Kiran Kumar, Catherine L Tooke, James Spencer, Robert S Paton, Jürgen Brem, Christopher J Schofield
A New Mechanism for β-Lactamases: Class D Enzymes Degrade 1β-Methyl Carbapenems through Lactone Formation. Angewandte Chemie (International ed. in English) 57 (5) (2018)
Christopher T Lohans, David Y Wang, Christian Jorgensen, Samuel T Cahill, Ian J Clifton, Michael A McDonough, Henry P Oswin, James Spencer, Carmen Domene, Timothy D W Claridge, Jürgen Brem, Christopher J Schofield
13C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions. Organic & biomolecular chemistry 15 (28) (2018)
Christopher T Lohans, Jürgen Brem, Christopher J Schofield
New Delhi Metallo-β-Lactamase 1 Catalyzes Avibactam and Aztreonam Hydrolysis. Antimicrobial agents and chemotherapy 61 (12) (2017)
Guo-Bo Li, Zhu-Jun Yu, Sha Liu, Lu-Yi Huang, Ling-Ling Yang, Christopher T Lohans, Sheng-Yong Yang
IFPTarget: A Customized Virtual Target Identification Method Based on Protein-Ligand Interaction Fingerprinting Analyses. Journal of chemical information and modeling 57 (7) (2017)
Tzu-Lan Yeh, Thomas M Leissing, Martine I Abboud, Cyrille C Thinnes, Onur Atasoylu, James P Holt-Martyn, Dong Zhang, Anthony Tumber, Kerstin Lippl, Christopher T Lohans, Ivanhoe K H Leung, Helen Morcrette, Ian J Clifton, Timothy D W Claridge, Akane Kawamura, Emily Flashman, Xin Lu, Peter J Ratcliffe, Rasheduzzaman Chowdhury, Christopher W Pugh, Christopher J Schofield
Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials. Chemical science 8 (11) (2017)

Christopher T Lohans.css-eqlu8i{font-size:small;padding-left:4px;} (Christopher Lohans)

Publication Activity (10 Years)

Top Topics

Top Venues

Christopher T Lohans (Christopher Lohans)