R Kiplin Guy (R Kip Guy)

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 25

Top Venues

Journal of medicinal chemistry

Nature communications

ACS chemical biology

Nature chemical biology

University of Kentucky

Scripps Research Institute (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Kentucky Oct 01 2016

United States

Dean of Pharmacy :: Pharmaceutical Sciences

St. Jude Children's Research Hospital Apr 01 2005 - Sep 30 2016

United States

Chairman :: Chemical BIology and Therapeutics

UCSF Medical Center Sep 01 1998 - Apr 01 2005

United States

Professor :: Pharmaceutical Chemistry

Education History

Scripps Research Institute Sep 01 1991 - May 30 1996

United States

PHD :: Chemistry

Publications

Angela K Carrillo, Tara Man Kadayat, Jong Yeon Hwang, Yizhe Chen, Fangyi Zhu, Gloria Holbrook, Kirsten Gillingwater, Michele C Connelly, Lei Yang, Marcel Kaiser, R Kiplin Guy
Antitrypanosomal Chloronitrobenzamides. Journal of medicinal chemistry 67 (5) (2024)
Angela K Carrillo, Tara Man Kadayat, Jong Yeon Hwang, Yizhe Chen, Fangyi Zhu, Gloria Holbrook, Kirsten Gillingwater, Michele C Connelly, Lei Yang, Marcel Kaiser, R Kiplin Guy
Antitrypanosomal Chloronitrobenzamides. Journal of medicinal chemistry 67 (5) (2024)
Angela K Carrillo, Tara Man Kadayat, Jong Yeon Hwang, Yizhe Chen, Fangyi Zhu, Gloria Holbrook, Kirsten Gillingwater, Michele C Connelly, Lei Yang, Marcel Kaiser, R Kiplin Guy
Antitrypanosomal Chloronitrobenzamides. Journal of medicinal chemistry (2024)
Jennifer L Kamens, Stephanie Nance, Cary Koss, Bei-Si Xu, Anitria Cotton, Jeannie W Lam, Elizabeth A R Garfinkle, Pratima Nallagatla, Amelia M R Smith, Sharnise Mitchell, Jing Ma, Duane Currier, Charlie Wright, Kanisha Kavdia, Vishwajeeth R Pagala, Wonil Kim, LaShanale M Wallace, Ji-Hoon Cho, Yiping Fan, Aman Seth, Nathaniel Twarog, John Kim Choi, Esther A Obeng, Mark E Hatley, Monika L Metzger, Hiroto Inaba, Sima Jeha, Jeffrey E Rubnitz, Junmin Peng, Taosheng Chen, Anang A Shelat, R Kiplin Guy, Tanja A Grüber
Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia. Nature communications 14 (1) (2023)
Ho Shin Kim, Diana Ortiz, Tara Man Kadayat, Corinne M Fargo, Jared T Hammill, Yizhe Chen, Amy L Rice, Kristin L Begley, Gaurav Shoeran, William Pistel, Phillip A Yates, Marco A Sanchez, Scott M Landfear, R Kiplin Guy
Optimization of Orally Bioavailable Antileishmanial 2,4,5-Trisubstituted Benzamides. Journal of medicinal chemistry (2023)
Jennifer L Kamens, Stephanie Nance, Cary Koss, Bei-Si Xu, Anitria Cotton, Jeannie W Lam, Elizabeth A R Garfinkle, Pratima Nallagatla, Amelia M R Smith, Sharnise Mitchell, Jing Ma, Duane Currier, Charlie Wright, Kanisha Kavdia, Vishwajeeth R Pagala, Wonil Kim, LaShanale M Wallace, Ji-Hoon Cho, Yiping Fan, Aman Seth, Nathaniel Twarog, John Kim Choi, Esther A Obeng, Mark E Hatley, Monika L Metzger, Hiroto Inaba, Sima Jeha, Jeffrey E Rubnitz, Junmin Peng, Taosheng Chen, Anang A Shelat, R Kiplin Guy, Tanja A Grüber
Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia. Nature communications 14 (1) (2023)
Jennifer L Kamens, Stephanie Nance, Cary Koss, Bei-Si Xu, Anitria Cotton, Jeannie W Lam, Elizabeth A R Garfinkle, Pratima Nallagatla, Amelia M R Smith, Sharnise Mitchell, Jing Ma, Duane Currier, William C Wright, Kanisha Kavdia, Vishwajeeth R Pagala, Wonil Kim, LaShanale M Wallace, Ji-Hoon Cho, Yiping Fan, Aman Seth, Nathaniel Twarog, John Kim Choi, Esther A Obeng, Mark E Hatley, Monika L Metzger, Hiroto Inaba, Sima Jeha, Jeffrey E Rubnitz, Junmin Peng, Taosheng Chen, Anang A Shelat, R Kiplin Guy, Tanja A Grüber
Author Correction: Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia. Nature communications 14 (1) (2023)
Jennifer L Kamens, Stephanie Nance, Cary Koss, Bei-Si Xu, Anitria Cotton, Jeannie W Lam, Elizabeth A R Garfinkle, Pratima Nallagatla, Amelia M R Smith, Sharnise Mitchell, Jing Ma, Duane Currier, Charlie Wright, Kanisha Kavdia, Vishwajeeth R Pagala, Wonil Kim, LaShanale M Wallace, Ji-Hoon Cho, Yiping Fan, Aman Seth, Nathaniel Twarog, John Kim Choi, Esther A Obeng, Mark E Hatley, Monika L Metzger, Hiroto Inaba, Sima Jeha, Jeffrey E Rubnitz, Junmin Peng, Taosheng Chen, Anang A Shelat, R Kiplin Guy, Tanja A Grüber
Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia. Nature communications 14 (1) (2023)
Jennifer L Kamens, Stephanie Nance, Cary Koss, Bei-Si Xu, Anitria Cotton, Jeannie W Lam, Elizabeth A R Garfinkle, Pratima Nallagatla, Amelia M R Smith, Sharnise Mitchell, Jing Ma, Duane Currier, William C Wright, Kanisha Kavdia, Vishwajeeth R Pagala, Wonil Kim, LaShanale M Wallace, Ji-Hoon Cho, Yiping Fan, Aman Seth, Nathaniel Twarog, John Kim Choi, Esther A Obeng, Mark E Hatley, Monika L Metzger, Hiroto Inaba, Sima Jeha, Jeffrey E Rubnitz, Junmin Peng, Taosheng Chen, Anang A Shelat, R Kiplin Guy, Tanja A Grüber
Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia. Nature communications 14 (1) (2023)
Jennifer L Kamens, Stephanie Nance, Cary Koss, Bei-Si Xu, Anitria Cotton, Jeannie W Lam, Elizabeth A R Garfinkle, Pratima Nallagatla, Amelia M R Smith, Sharnise Mitchell, Jing Ma, Duane Currier, Charlie Wright, Kanisha Kavdia, Vishwajeeth R Pagala, Wonil Kim, LaShanale M Wallace, Ji-Hoon Cho, Yiping Fan, Aman Seth, Nathaniel Twarog, John Kim Choi, Esther A Obeng, Mark E Hatley, Monika L Metzger, Hiroto Inaba, Sima Jeha, Jeffrey E Rubnitz, Junmin Peng, Taosheng Chen, Anang A Shelat, R Kiplin Guy, Tanja A Grüber
Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia. Nature communications 14 (1) (2023)
Jennifer L Kamens, Stephanie Nance, Cary Koss, Bei-Si Xu, Anitria Cotton, Jeannie W Lam, Elizabeth A R Garfinkle, Pratima Nallagatla, Amelia M R Smith, Sharnise Mitchell, Jing Ma, Duane Currier, William C Wright, Kanisha Kavdia, Vishwajeeth R Pagala, Wonil Kim, LaShanale M Wallace, Ji-Hoon Cho, Yiping Fan, Aman Seth, Nathaniel Twarog, John Kim Choi, Esther A Obeng, Mark E Hatley, Monika L Metzger, Hiroto Inaba, Sima Jeha, Jeffrey E Rubnitz, Junmin Peng, Taosheng Chen, Anang A Shelat, R Kiplin Guy, Tanja A Grüber
Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia. Nature communications 14 (1) (2023)
Jennifer L Kamens, Stephanie Nance, Cary Koss, Bei-Si Xu, Anitria Cotton, Jeannie W Lam, Elizabeth A R Garfinkle, Pratima Nallagatla, Amelia M R Smith, Sharnise Mitchell, Jing Ma, Duane Currier, William C Wright, Kanisha Kavdia, Vishwajeeth R Pagala, Wonil Kim, LaShanale M Wallace, Ji-Hoon Cho, Yiping Fan, Aman Seth, Nathaniel Twarog, John Kim Choi, Esther A Obeng, Mark E Hatley, Monika L Metzger, Hiroto Inaba, Sima Jeha, Jeffrey E Rubnitz, Junmin Peng, Taosheng Chen, Anang A Shelat, R Kiplin Guy, Tanja A Grüber
Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia. Nature communications 14 (1) (2023)
Ho Shin Kim, Jared T Hammill, Daniel C Scott, Yizhe Chen, Amy L Rice, William Pistel, Bhuvanesh Singh, Brenda A Schulman, R Kiplin Guy
Improvement of Oral Bioavailability of Pyrazolo-Pyridone Inhibitors of the Interaction of DCN1/2 and UBE2M. Journal of medicinal chemistry 64 (9) (2021)
Jared T Hammill, Vitaliy M Sviripa, Liliia M Kril, Diana Ortiz, Corinne M Fargo, Ho Shin Kim, Yizhe Chen, Jonah Rector, Amy L Rice, Malgorzata A Domagalska, Kristin L Begley, Chunming Liu, Vivek M Rangnekar, Jean-Claude Dujardin, David S Watt, Scott M Landfear, R Kiplin Guy
Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents. Journal of medicinal chemistry 64 (16) (2021)
Scott Eagon, Jared T Hammill, Martina Sigal, Kevin J Ahn, Julia E Tryhorn, Grant Koch, Briana Belanger, Cory A Chaplan, Lauren Loop, Anna S Kashtanova, Kenya Yniguez, Horacio Lazaro, Steven P Wilkinson, Amy L Rice, Mofolusho O Falade, Rei Takahashi, Katie Kim, Ashley Cheung, Celine DiBernardo, Joshua J Kimball, Elizabeth A Winzeler, Korina Eribez, Nimisha Mittal, Francisco-Javier Gamo, Benigno Crespo, Alisje Churchyard, Irene García-Barbazán, Jake Baum, Marc O Anderson, Benoît Laleu, R Kiplin Guy
Synthesis and Structure-Activity Relationship of Dual-Stage Antimalarial Pyrazolo[3,4-b]pyridines. Journal of medicinal chemistry 63 (20) (2020)
Christina D Drenberg, Anang A Shelat, Jinjun Dang, Anitria Cotton, Shelley J Orwick, Mengyu Li, Jae Yoon Jeon, Qiang Fu, Daelynn R Buelow, Marissa Pioso, Shuiying Hu, Hiroto Inaba, Raul C Ribeiro, Jeffrey E Rubnitz, Tanja A Gruber, R Kiplin Guy, Sharyn D Baker
A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatric AML. Nature communications 10 (1) (2019)
Ho Shin Kim, Jared T Hammill, Daniel C Scott, Yizhe Chen, Jaeki Min, Jonah Rector, Bhuvanesh Singh, Brenda A Schulman, R Kiplin Guy
Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation. Journal of medicinal chemistry 62 (18) (2019)
Jamie R Genthe, Jaeki Min, Dana M Farmer, Anang A Shelat, Jose A Grenet, Wenwei Lin, David Finkelstein, Karen Vrijens, Taosheng Chen, R Kiplin Guy, Wilson K Clements, Martine F Roussel
Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway. ACS chemical biology 14 (7) (2019)
Jared T Hammill, Deepak Bhasin, Daniel C Scott, Jaeki Min, Yizhe Chen, Yan Lu, Lei Yang, Ho Shin Kim, Michele C Connelly, Courtney Hammill, Gloria Holbrook, Cynthia Jeffries, Bhuvanesh Singh, Brenda A Schulman, R Kiplin Guy
Discovery of an Orally Bioavailable Inhibitor of Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation. Journal of medicinal chemistry 61 (7) (2018)
Jared T Hammill, Daniel C Scott, Jaeki Min, Michele C Connelly, Gloria Holbrook, Fangyi Zhu, Amy Matheny, Lei Yang, Bhuvanesh Singh, Brenda A Schulman, R Kiplin Guy
Piperidinyl Ureas Chemically Control Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation. Journal of medicinal chemistry 61 (7) (2018)
Andreas Verras, Chris L Waller, Peter Gedeck, Darren V S Green, Thierry Kogej, Anandkumar Raichurkar, Manoranjan Panda, Anang A Shelat, Julie Clark, R Kiplin Guy, George Papadatos, Jeremy Burrows
Shared Consensus Machine Learning Models for Predicting Blood Stage Malaria Inhibition. Journal of chemical information and modeling 57 (3) (2017)
Jamie R Genthe, Jaeki Min, Dana M Farmer, Anang A Shelat, Jose A Grenet, Wenwei Lin, David Finkelstein, Karen Vrijens, Taosheng Chen, R Kiplin Guy, Wilson K Clements, Martine F Roussel
Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway. ACS chemical biology 12 (9) (2017)
Daniel C Scott, Jared T Hammill, Jaeki Min, David Y Rhee, Michele Connelly, Vladislav O Sviderskiy, Deepak Bhasin, Yizhe Chen, Su-Sien Ong, Sergio C Chai, Asli N Goktug, Guochang Huang, Julie K Monda, Jonathan Low, Ho Shin Kim, Joao A Paulo, Joe R Cannon, Anang A Shelat, Taosheng Chen, Ian R Kelsall, Arno F Alpi, Vishwajeeth Pagala, Xusheng Wang, Junmin Peng, Bhuvanesh Singh, J Wade Harper, Brenda A Schulman, R Kiplin Guy
Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase. Nature chemical biology 13 (8) (2017)
Ho Shin Kim, Jared T Hammill, R Kiplin Guy
Seeking the Elusive Long-Acting Ozonide: Discovery of Artefenomel (OZ439). Journal of medicinal chemistry 60 (7) (2017)
Jin Zhang, John J Bowling, David Smithson, Julie Clark, Melissa R Jacob, Shabana I Khan, Babu L Tekwani, Michele Connelly, Vladimir Samoylenko, Mohamed A Ibrahim, Mohamed A Zaki, Mei Wang, John P Hester, Ying Tu, Cynthia Jeffries, Nathaniel Twarog, Anang A Shelat, Larry A Walker, Ilias Muhammad, R Kiplin Guy
Diversity-oriented natural product platform identifies plant constituents targeting Plasmodium falciparum. Malaria journal 15 (1) (2016)

R Kiplin Guy.css-eqlu8i{font-size:small;padding-left:4px;} (R Kip Guy)

Publication Activity (10 Years)

Top Topics

Top Venues

R Kiplin Guy (R Kip Guy)