Rahul M Kohli

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 45

Top Topics

Top Venues

ACS chemical biology

Nature communications

Nature biotechnology

Nucleic acids research

This page only lists publications with an associated author ORCID identifier.

Publications

Hugo C Medina-Munoz, Eric Kofman, Pratibha Jagannatha, Evan A Boyle, Tao Yu, Krysten L Jones, Jasmine R Mueller, Grace D Lykins, Andrew T Doudna, Samuel S Park, Steven M Blue, Brodie L Ranzau, Rahul M Kohli, Alexis C Komor, Gene W Yeo
Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies. Nature communications 15 (1) (2024)
Hugo C Medina-Munoz, Eric Kofman, Pratibha Jagannatha, Evan A Boyle, Tao Yu, Krysten L Jones, Jasmine R Mueller, Grace D Lykins, Andrew T Doudna, Samuel S Park, Steven M Blue, Brodie L Ranzau, Rahul M Kohli, Alexis C Komor, Gene W Yeo
Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies. Nature communications 15 (1) (2024)
Michael B Cory, Allen Li, Christina M Hurley, Peter J Carman, Ruth A Pumroy, Zachary M Hostetler, Ryann M Perez, Yarra Venkatesh, Xinning Li, Kushol Gupta, E James Petersson, Rahul M Kohli
The LexA-RecA* structure reveals a cryptic lock-and-key mechanism for SOS activation. Nature structural & molecular biology (2024)
Kiara N Berríos, Aleksia Barka, Jasleen Gill, Juan C Serrano, Peter F Bailer, Jared B Parker, Niklaus H Evitt, Kiran S Gajula, Junwei Shi, Rahul M Kohli
Cooperativity between Cas9 and hyperactive AID establishes broad and diversifying mutational footprints in base editors. Nucleic acids research 52 (4) (2024)
Kiara N Berríos, Aleksia Barka, Jasleen Gill, Juan C Serrano, Peter F Bailer, Jared B Parker, Niklaus H Evitt, Kiran S Gajula, Junwei Shi, Rahul M Kohli
Cooperativity between Cas9 and hyperactive AID establishes broad and diversifying mutational footprints in base editors. Nucleic acids research 52 (4) (2024)
Hugo C Medina-Munoz, Eric Kofman, Pratibha Jagannatha, Evan A Boyle, Tao Yu, Krysten L Jones, Jasmine R Mueller, Grace D Lykins, Andrew T Doudna, Samuel S Park, Steven M Blue, Brodie L Ranzau, Rahul M Kohli, Alexis C Komor, Gene W Yeo
Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies. Nature communications 15 (1) (2024)
Hugo C Medina-Munoz, Eric Kofman, Pratibha Jagannatha, Evan A Boyle, Tao Yu, Krysten L Jones, Jasmine R Mueller, Grace D Lykins, Andrew T Doudna, Samuel S Park, Steven M Blue, Brodie L Ranzau, Rahul M Kohli, Alexis C Komor, Gene W Yeo
Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies. Nature communications 15 (1) (2024)
Hugo C Medina-Munoz, Eric Kofman, Pratibha Jagannatha, Evan A Boyle, Tao Yu, Krysten L Jones, Jasmine R Mueller, Grace D Lykins, Andrew T Doudna, Samuel S Park, Steven M Blue, Brodie L Ranzau, Rahul M Kohli, Alexis C Komor, Gene W Yeo
Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies. Nature communications 15 (1) (2024)
Kiara N Berríos, Aleksia Barka, Jasleen Gill, Juan C Serrano, Peter F Bailer, Jared B Parker, Niklaus H Evitt, Kiran S Gajula, Junwei Shi, Rahul M Kohli
Cooperativity between Cas9 and hyperactive AID establishes broad and diversifying mutational footprints in base editors. Nucleic acids research 52 (4) (2024)
Kiara N Berríos, Aleksia Barka, Jasleen Gill, Juan C Serrano, Peter F Bailer, Jared B Parker, Niklaus H Evitt, Kiran S Gajula, Junwei Shi, Rahul M Kohli
Cooperativity between Cas9 and hyperactive AID establishes broad and diversifying mutational footprints in base editors. Nucleic acids research (2024)
Hugo C Medina-Munoz, Eric Kofman, Pratibha Jagannatha, Evan A Boyle, Tao Yu, Krysten L Jones, Jasmine R Mueller, Grace D Lykins, Andrew T Doudna, Samuel S Park, Steven M Blue, Brodie L Ranzau, Rahul M Kohli, Alexis C Komor, Gene W Yeo
Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies. Nature communications 15 (1) (2024)
Kiara N Berríos, Aleksia Barka, Jasleen Gill, Juan C Serrano, Peter F Bailer, Jared B Parker, Niklaus H Evitt, Kiran S Gajula, Junwei Shi, Rahul M Kohli
Cooperativity between Cas9 and hyperactive AID establishes broad and diversifying mutational footprints in base editors. Nucleic acids research (2024)
Hugo C Medina-Munoz, Eric Kofman, Pratibha Jagannatha, Evan A Boyle, Tao Yu, Krysten L Jones, Jasmine R Mueller, Grace D Lykins, Andrew T Doudna, Samuel S Park, Steven M Blue, Brodie L Ranzau, Rahul M Kohli, Alexis C Komor, Gene W Yeo
Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies. Nature communications 15 (1) (2024)
Tong Wang, Johanna M Fowler, Laura Liu, Christian E Loo, Meiqi Luo, Emily K Schutsky, Kiara N Berríos, Jamie E DeNizio, Ashley Dvorak, Nick Downey, Saira Montermoso, Bianca Y Pingul, MacLean Nasrallah, Walraj S Gosal, Hao Wu, Rahul M Kohli
Direct enzymatic sequencing of 5-methylcytosine at single-base resolution. Nature chemical biology (2023)
Zhen Zhang, Amy E Baxter, Diqiu Ren, Kunhua Qin, Zeyu Chen, Sierra M Collins, Hua Huang, Chad A Komar, Peter F Bailer, Jared B Parker, Gerd A Blobel, Rahul M Kohli, E John Wherry, Shelley L Berger, Junwei Shi
Efficient engineering of human and mouse primary cells using peptide-assisted genome editing. Nature biotechnology (2023)
Emily B Fabyanic, Peng Hu, Qi Qiu, Kiara N Berríos, Daniel R Connolly, Tong Wang, Jennifer Flournoy, Zhaolan Zhou, Rahul M Kohli, Hao Wu
Joint single-cell profiling resolves 5mC and 5hmC and reveals their distinct gene regulatory effects. Nature biotechnology (2023)
Zhen Zhang, Amy E Baxter, Diqiu Ren, Kunhua Qin, Zeyu Chen, Sierra M Collins, Hua Huang, Chad A Komar, Peter F Bailer, Jared B Parker, Gerd A Blobel, Rahul M Kohli, E John Wherry, Shelley L Berger, Junwei Shi
Efficient engineering of human and mouse primary cells using peptide-assisted genome editing. Nature biotechnology (2023)
Martyna W Sroka, Damianos Skopelitis, Marit W Vermunt, Jonathan B Preall, Osama El Demerdash, Larissa M N de Almeida, Kenneth Chang, Raditya Utama, Berkley E Gryder, Giuseppina Caligiuri, Diqiu Ren, Benan Nalbant, Joseph P Milazzo, David A Tuveson, Alexander Dobin, Scott W Hiebert, Kristy R Stengel, Roberto Mantovani, Javed Khan, Rahul M Kohli, Junwei Shi, Gerd A Blobel, Christopher R Vakoc
Myo-differentiation reporter screen reveals NF-Y as an activator of PAX3-FOXO1 in rhabdomyosarcoma. Proceedings of the National Academy of Sciences of the United States of America 120 (36) (2023)
Christian E Loo, Mark A Hix, Tong Wang, Gerardo Andrés Cisneros, Rahul M Kohli
Revealing Drivers for Carboxy- S -adenosyl-l-methionine Use by Neomorphic Variants of a DNA Methyltransferase. ACS chemical biology (2023)
Zhen Zhang, Amy E Baxter, Diqiu Ren, Kunhua Qin, Zeyu Chen, Sierra M Collins, Hua Huang, Chad A Komar, Peter F Bailer, Jared B Parker, Gerd A Blobel, Rahul M Kohli, E John Wherry, Shelley L Berger, Junwei Shi
Efficient engineering of human and mouse primary cells using peptide-assisted genome editing. Nature biotechnology (2023)
Anna H Yeaton, Geraldine Cayanan, Sanam Loghavi, Igor Dolgalev, Emmett M Leddin, Christian E Loo, Hedieh Torabifard, Deedra Nicolet, Jingjing Wang, Kate Corrigan, Varvara Paraskevopoulou, Daniel T Starczynowski, Eric Wang, Omar Abdel-Wahab, Aaron D Viny, Richard M Stone, John C Byrd, Olga A Guryanova, Rahul M Kohli, Gerardo Andrés Cisneros, Aristotelis Tsirigos, Ann-Kathrin Eisfeld, Iannis Aifantis, Maria Guillamot
The Impact of Inflammation-Induced Tumor Plasticity during Myeloid Transformation. Cancer discovery 12 (10) (2022)
Juan C Serrano, Dora von Trentini, Kiara N Berríos, Aleksia Barka, Ivan J Dmochowski, Rahul M Kohli
Structure-Guided Design of a Potent and Specific Inhibitor against the Genomic Mutator APOBEC3A. ACS chemical biology 17 (12) (2022)
Juan C Serrano, Dora von Trentini, Kiara N Berríos, Aleksia Barka, Ivan J Dmochowski, Rahul M Kohli
Structure-Guided Design of a Potent and Specific Inhibitor against the Genomic Mutator APOBEC3A. ACS chemical biology 17 (12) (2022)
Aleksia Barka, Kiara N Berríos, Peter Bailer, Emily K Schutsky, Tong Wang, Rahul M Kohli
The Base-Editing Enzyme APOBEC3A Catalyzes Cytosine Deamination in RNA with Low Proficiency and High Selectivity. ACS chemical biology 17 (3) (2022)
Juan C Serrano, Dora von Trentini, Kiara N Berríos, Aleksia Barka, Ivan J Dmochowski, Rahul M Kohli
Structure-Guided Design of a Potent and Specific Inhibitor against the Genomic Mutator APOBEC3A. ACS chemical biology 17 (12) (2022)
Michael B Cory, Allen Li, Christina M Hurley, Zachary M Hostetler, Yarra Venkatesh, Chloe M Jones, E James Petersson, Rahul M Kohli
Engineered RecA Constructs Reveal the Minimal SOS Activation Complex. Biochemistry (2022)
Juan C Serrano, Dora von Trentini, Kiara N Berríos, Aleksia Barka, Ivan J Dmochowski, Rahul M Kohli
Structure-Guided Design of a Potent and Specific Inhibitor against the Genomic Mutator APOBEC3A. ACS chemical biology 17 (12) (2022)
Rahul M Kohli, Stuart N Isaacs
Has the current monkeypox outbreak revealed a pox on 'U'? The Journal of infectious diseases (2022)
Juan C Serrano, Dora von Trentini, Kiara N Berríos, Aleksia Barka, Ivan J Dmochowski, Rahul M Kohli
Structure-Guided Design of a Potent and Specific Inhibitor against the Genomic Mutator APOBEC3A. ACS chemical biology 17 (12) (2022)
Meng-Ju Wu, Lei Shi, Juan Dubrot, Joshua Merritt, Vindhya Vijay, Ting-Yu Wei, Emily A Kessler, Kira E Olander, Ramzi Adil, Amaya Pankaj, Krishna Seshu Tummala, Vajira K Weerasekara, Yuanli Zhen, Qibiao Wu, Meiqi Luo, William Shen, Maria Garcia-Beccaria, Mirian Fernandez-Vaquero, Christine Hudson, Sebastien Ronseaux, Yi Sun, Rodrigo Saad Berreta, Russell William Jenkins, Tong Wang, Mathias Heikenwalder, Cristina R Ferrone, Lipika Goyal, Brandon Nicolay, Vikram Deshpande, Rahul M Kohli, Hongwu Zheng, Robert T Manguso, Nabeel Bardeesy
Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma. Cancer discovery (2021)
Juan Alvarez-Gonzalez, Adam Yasgar, Robert W Maul, Amanda E Rieffer, Daniel J Crawford, Daniel J Salamango, Dorjbal Dorjsuren, Alexey V Zakharov, Daniel J Jansen, Ganesha Rai, Juan Jose Marugan, Anton Simeonov, Reuben S Harris, Rahul M Kohli, Patricia J Gearhart
Small Molecule Inhibitors of Activation-Induced Deaminase Decrease Class Switch Recombination in B Cells. ACS pharmacology & translational science 4 (3) (2021)
Kiara N Berríos, Niklaus H Evitt, Rachel A DeWeerd, Diqiu Ren, Meiqi Luo, Aleksia Barka, Tong Wang, Caroline R Bartman, Yemin Lan, Abby M Green, Junwei Shi, Rahul M Kohli
Controllable genome editing with split-engineered base editors. Nature chemical biology 17 (12) (2021)
Rodrigo A Gier, Krista A Budinich, Niklaus H Evitt, Zhendong Cao, Elizabeth S Freilich, Qingzhou Chen, Jun Qi, Yemin Lan, Rahul M Kohli, Junwei Shi
High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening. Nature communications 11 (1) (2020)
Houra Merrikh, Rahul M Kohli
Targeting evolution to inhibit antibiotic resistance. The FEBS journal 287 (20) (2020)
Uday Ghanty, Tong Wang, Rahul M Kohli
Nucleobase Modifiers Identify TET Enzymes as Bifunctional DNA Dioxygenases Capable of Direct N-Demethylation. Angewandte Chemie (International ed. in English) 59 (28) (2020)
Zachary M Hostetler, Michael B Cory, Chloe M Jones, E James Petersson, Rahul M Kohli
The Kinetic and Molecular Basis for the Interaction of LexA and Activated RecA Revealed by a Fluorescent Amino Acid Probe. ACS chemical biology 15 (5) (2020)
Amanda N Samuels, Manuela Roggiani, Jun Zhu, Mark Goulian, Rahul M Kohli
The SOS Response Mediates Sustained Colonization of the Mammalian Gut. Infection and immunity 87 (2) (2019)
Jamie E DeNizio, Monica Yun Liu, Emmett M Leddin, Gerardo Andrés Cisneros, Rahul M Kohli
Selectivity and Promiscuity in TET-Mediated Oxidation of 5-Methylcytosine in DNA and RNA. Biochemistry 58 (5) (2018)
Emily K Schutsky, Jamie E DeNizio, Peng Hu, Monica Yun Liu, Christopher S Nabel, Emily B Fabyanic, Young Hwang, Frederic D Bushman, Hao Wu, Rahul M Kohli
Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase. Nature biotechnology (2018)
Uday Ghanty, Jamie E DeNizio, Monica Yun Liu, Rahul M Kohli
Exploiting Substrate Promiscuity To Develop Activity-Based Probes for Ten-Eleven Translocation Family Enzymes. Journal of the American Chemical Society 140 (50) (2018)
Charlie Y Mo, Matthew J Culyba, Trevor Selwood, Jeffrey M Kubiak, Zachary M Hostetler, Anthony J Jurewicz, Paul M Keller, Andrew J Pope, Amy Quinn, Jessica Schneck, Katherine L Widdowson, Rahul M Kohli
Inhibitors of LexA Autoproteolysis and the Bacterial SOS Response Discovered by an Academic-Industry Partnership. ACS infectious diseases 4 (3) (2018)
Zachary M Hostetler, John J Ferrie, Marc R Bornstein, Itthipol Sungwienwong, E James Petersson, Rahul M Kohli
Systematic Evaluation of Soluble Protein Expression Using a Fluorescent Unnatural Amino Acid Reveals No Reliable Predictors of Tolerability. ACS chemical biology 13 (10) (2018)
Matthew J Culyba, Jeffrey M Kubiak, Charlie Y Mo, Mark Goulian, Rahul M Kohli
Non-equilibrium repressor binding kinetics link DNA damage dose to transcriptional timing within the SOS gene network. PLoS genetics 14 (6) (2018)
Jeffrey M Kubiak, Matthew J Culyba, Monica Yun Liu, Charlie Y Mo, Mark Goulian, Rahul M Kohli
A Small-Molecule Inducible Synthetic Circuit for Control of the SOS Gene Network without DNA Damage. ACS synthetic biology 6 (11) (2017)
Christopher S Nabel, Jamie E DeNizio, Martin Carroll, Rahul M Kohli
DNA Methyltransferases Demonstrate Reduced Activity against Arabinosylcytosine: Implications for Epigenetic Instability in Acute Myeloid Leukemia. Biochemistry 56 (16) (2017)