Richard J A Goodwin (Richard Goodwin)

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 25

Top Venues

Nature communications

Metabolites

Nature protocols

Angewandte Chemie (Weinheim an der Bergstrasse, Germany)

AstraZeneca R&D Cambridge

This page only lists publications with an associated author ORCID identifier.

Affiliation History

AstraZeneca R&D Cambridge

United Kingdom

Director :: Imaging and Data Analytics, Clinical Pharmacology and Safety Sciences

Publications

Andreas Dannhorn, Emine Kazanc, Lucy Flint, Fei Guo, Alfie Carter, Andrew R Hall, Stewart A Jones, George Poulogiannis, Simon T Barry, Owen James Sansom, Josephine Bunch, Zoltan Takats, Richard J A Goodwin
Morphological and molecular preservation through universal preparation of fresh-frozen tissue samples for multimodal imaging workflows. Nature protocols (2024)
Richard J A Goodwin, Stefan J Platz, Jorge Sergio Reis-Filho, Simon T Barry
Accelerating Drug Development Using Spatial Multi-omics. Cancer discovery 14 (4) (2024)
Nikita Sushentsev, Gregory Hamm, Lucy Flint, Daniel Birtles, Aleksandr Zakirov, Jack Richings, Stephanie Ling, Jennifer Y Tan, Mary A McLean, Vinay Ayyappan, Ines Horvat Menih, Cara Brodie, Jodi L Miller, Ian Geoffrey Mills, Vincent J Gnanapragasam, Anne Y Warren, Simon T Barry, Richard J A Goodwin, Tristan Barrett, Ferdia A Gallagher
Metabolic imaging across scales reveals distinct prostate cancer phenotypes. Nature communications 15 (1) (2024)
Sophie M Pearce, Neil A Cross, David P Smith, Malcolm R Clench, Lucy E Flint, Gregory Hamm, Richard J A Goodwin, James I Langridge, Emmanuelle Claude, Laura M Cole
Multimodal Mass Spectrometry Imaging of an Osteosarcoma Multicellular Tumour Spheroid Model to Investigate Drug-Induced Response. Metabolites 14 (6) (2024)
Nikita Sushentsev, Gregory Hamm, Lucy Flint, Daniel Birtles, Aleksandr Zakirov, Jack Richings, Stephanie Ling, Jennifer Y Tan, Mary A McLean, Vinay Ayyappan, Ines Horvat Menih, Cara Brodie, Jodi L Miller, Ian Geoffrey Mills, Vincent J Gnanapragasam, Anne Y Warren, Simon T Barry, Richard J A Goodwin, Tristan Barrett, Ferdia A Gallagher
Metabolic imaging across scales reveals distinct prostate cancer phenotypes. Nature communications 15 (1) (2024)
Sophie M Pearce, Neil A Cross, David P Smith, Malcolm R Clench, Lucy E Flint, Gregory Hamm, Richard J A Goodwin, James I Langridge, Emmanuelle Claude, Laura M Cole
Multimodal Mass Spectrometry Imaging of an Osteosarcoma Multicellular Tumour Spheroid Model to Investigate Drug-Induced Response. Metabolites 14 (6) (2024)
Sophie M Pearce, Neil A Cross, David P Smith, Malcolm R Clench, Lucy E Flint, Gregory Hamm, Richard J A Goodwin, James I Langridge, Emmanuelle Claude, Laura M Cole
Multimodal Mass Spectrometry Imaging of an Osteosarcoma Multicellular Tumour Spheroid Model to Investigate Drug-Induced Response. Metabolites 14 (6) (2024)
Nikita Sushentsev, Gregory Hamm, Lucy Flint, Daniel Birtles, Aleksandr Zakirov, Jack Richings, Stephanie Ling, Jennifer Y Tan, Mary A McLean, Vinay Ayyappan, Ines Horvat Menih, Cara Brodie, Jodi L Miller, Ian Geoffrey Mills, Vincent J Gnanapragasam, Anne Y Warren, Simon T Barry, Richard J A Goodwin, Tristan Barrett, Ferdia A Gallagher
Metabolic imaging across scales reveals distinct prostate cancer phenotypes. Nature communications 15 (1) (2024)
Peter A Kreuzaler, Paolo Inglese, Avinash D Ghanate, Ersa Gjelaj, Vincen Wu, Yulia Panina, Andres Mendez-Lucas, Catherine MacLachlan, Neill Patani, Catherine B Hubert, Helen Huang, Gina Greenidge, Oscar M Rueda, Adam J Taylor, Evdoxia Karali, Emine Kazanc, Amy R Spicer-Hadlington, Alex Dexter, Wei Lin, Daria Thompson, Mariana Silva Dos Santos, Enrica Calvani, Nathalie M Legrave, James K Ellis, Wendy Greenwood, Mary Green, Emma Nye, Emma Still, null null, Simon T Barry, Richard J A Goodwin, Alejandra Bruna, Carlos Caldas, James I MacRae, Luiz Pedro Sório de Carvalho, George Poulogiannis, Greg McMahon, Zoltán Takáts, Josephine Bunch, Mariia O Yuneva
Vitamin B 5 supports MYC oncogenic metabolism and tumor progression in breast cancer. Nature metabolism (2023)
Johan Vande Voorde, Rory T Steven, Arafath K Najumudeen, Catriona A Ford, Alex Dexter, Ariadna Gonzalez-Fernandez, Chelsea J Nikula, Yuchen Xiang, Lauren Ford, Stefania Maneta Stavrakaki, Kathryn L Gilroy, Lucas B Zeiger, Kathryn Pennel, Phimmada Hatthakarnkul, Efstathios A Elia, Ammar Nasif, Teresa Murta, Eftychios Manoli, Sam Mason, Michael Gillespie, Tamsin R M Lannagan, Nikola Vlahov, Rachel A Ridgway, Colin Nixon, Alexander Raven, Megan Mills, Dimitris Athineos, Georgios Kanellos, Craig Nourse, David M Gay, Mark Hughes, Amy Burton, Bin Yan, Katherine Sellers, Vincen Wu, Kobe De Ridder, Engy Shokry, Alejandro Huerta Uribe, William Clark, Graeme Clark, Kristina Kirschner, Bernard Thienpont, Vivian Sze Wing Li, Oliver D K Maddocks, Simon T Barry, Richard J A Goodwin, James Macalister Kinross, Joanne Edwards, Mariia O Yuneva, David Sumpton, Zoltán Takáts, Andrew D Campbell, Josephine Bunch, Owen James Sansom
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target. Nature metabolism (2023)
Nikita Sushentsev, Gregory Hamm, Jack Richings, Mary A McLean, Ines Horvat Menih, Vinay Ayyappan, Ian Geoffrey Mills, Anne Y Warren, Vincent J Gnanapragasam, Simon T Barry, Richard J A Goodwin, Ferdia A Gallagher, Tristan Barrett
Imaging tumor lactate is feasible for identifying intermediate-risk prostate cancer patients with postsurgical biochemical recurrence. Proceedings of the National Academy of Sciences of the United States of America 120 (49) (2023)
Sally J Adua, Anna Arnal-Estape, Minghui Zhao, Bowen Qi, Zongzhi Z Liu, Carolyn Kravitz, Heather Hulme, Nicole Strittmatter, Francesc Lopez, Sampada Chande, Alexandra E Albert, Mary-Ann Melnick, Bomiao Hu, Katerina Politi, Veronica Chiang, Nicola Colclough, Richard J A Goodwin, Darren Ae Cross, Paul D Smith, Don X Nguyen
Brain metastatic outgrowth and osimertinib resistance are potentiated by RhoA in EGFR-mutant lung cancer. Nature communications 13 (1) (2022)
Sally J Adua, Anna Arnal-Estape, Minghui Zhao, Bowen Qi, Zongzhi Z Liu, Carolyn Kravitz, Heather Hulme, Nicole Strittmatter, Francesc Lopez, Sampada Chande, Alexandra E Albert, Mary-Ann Melnick, Bomiao Hu, Katerina Politi, Veronica Chiang, Nicola Colclough, Richard J A Goodwin, Darren Ae Cross, Paul D Smith, Don X Nguyen
Brain metastatic outgrowth and osimertinib resistance are potentiated by RhoA in EGFR-mutant lung cancer. Nature communications 13 (1) (2022)
Eva Illes-Toth, Oliver J Hale, James W Hughes, Nicole Strittmatter, Jonathan Rose, Ben Clayton, Rebecca Sargeant, Stewart Jones, Andreas Dannhorn, Richard J A Goodwin, Helen J Cooper
Mass Spectrometry Detection and Imaging of a Non-Covalent Protein-Drug Complex in Tissue from Orally Dosed Rats. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 134 (36) (2022)
Sally J Adua, Anna Arnal-Estape, Minghui Zhao, Bowen Qi, Zongzhi Z Liu, Carolyn Kravitz, Heather Hulme, Nicole Strittmatter, Francesc Lopez, Sampada Chande, Alexandra E Albert, Mary-Ann Melnick, Bomiao Hu, Katerina Politi, Veronica Chiang, Nicola Colclough, Richard J A Goodwin, Darren Ae Cross, Paul D Smith, Don X Nguyen
Brain metastatic outgrowth and osimertinib resistance are potentiated by RhoA in EGFR-mutant lung cancer. Nature communications 13 (1) (2022)
Sally J Adua, Anna Arnal-Estape, Minghui Zhao, Bowen Qi, Zongzhi Z Liu, Carolyn Kravitz, Heather Hulme, Nicole Strittmatter, Francesc Lopez, Sampada Chande, Alexandra E Albert, Mary-Ann Melnick, Bomiao Hu, Katerina Politi, Veronica Chiang, Nicola Colclough, Richard J A Goodwin, Darren Ae Cross, Paul D Smith, Don X Nguyen
Brain metastatic outgrowth and osimertinib resistance are potentiated by RhoA in EGFR-mutant lung cancer. Nature communications 13 (1) (2022)
Sally J Adua, Anna Arnal-Estape, Minghui Zhao, Bowen Qi, Zongzhi Z Liu, Carolyn Kravitz, Heather Hulme, Nicole Strittmatter, Francesc Lopez, Sampada Chande, Alexandra E Albert, Mary-Ann Melnick, Bomiao Hu, Katerina Politi, Veronica Chiang, Nicola Colclough, Richard J A Goodwin, Darren Ae Cross, Paul D Smith, Don X Nguyen
Brain metastatic outgrowth and osimertinib resistance are potentiated by RhoA in EGFR-mutant lung cancer. Nature communications 13 (1) (2022)
Sally J Adua, Anna Arnal-Estape, Minghui Zhao, Bowen Qi, Zongzhi Z Liu, Carolyn Kravitz, Heather Hulme, Nicole Strittmatter, Francesc Lopez, Sampada Chande, Alexandra E Albert, Mary-Ann Melnick, Bomiao Hu, Katerina Politi, Veronica Chiang, Nicola Colclough, Richard J A Goodwin, Darren Ae Cross, Paul D Smith, Don X Nguyen
Brain metastatic outgrowth and osimertinib resistance are potentiated by RhoA in EGFR-mutant lung cancer. Nature communications 13 (1) (2022)
Sally J Adua, Anna Arnal-Estape, Minghui Zhao, Bowen Qi, Zongzhi Z Liu, Carolyn Kravitz, Heather Hulme, Nicole Strittmatter, Francesc Lopez, Sampada Chande, Alexandra E Albert, Mary-Ann Melnick, Bomiao Hu, Katerina Politi, Veronica Chiang, Nicola Colclough, Richard J A Goodwin, Darren Ae Cross, Paul D Smith, Don X Nguyen
Brain metastatic outgrowth and osimertinib resistance are potentiated by RhoA in EGFR-mutant lung cancer. Nature communications 13 (1) (2022)
Eva Illes-Toth, Oliver J Hale, James W Hughes, Nicole Strittmatter, Jonathan Rose, Ben Clayton, Rebecca Sargeant, Stewart Jones, Andreas Dannhorn, Richard J A Goodwin, Helen J Cooper
Mass Spectrometry Detection and Imaging of a Non-Covalent Protein-Drug Complex in Tissue from Orally Dosed Rats. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 134 (36) (2022)
Eva Illes-Toth, Oliver J Hale, James W Hughes, Nicole Strittmatter, Jonathan Rose, Ben Clayton, Rebecca Sargeant, Stewart Jones, Andreas Dannhorn, Richard J A Goodwin, Helen J Cooper
Mass Spectrometry Detection and Imaging of a Non-Covalent Protein-Drug Complex in Tissue from Orally Dosed Rats. Angewandte Chemie (International ed. in English) 61 (36) (2022)
Arafath K Najumudeen, Fatih Ceteci, Sigrid K Fey, Gregory Hamm, Rory T Steven, Holly Hall, Chelsea J Nikula, Alex Dexter, Teresa Murta, Alan M Race, David Sumpton, Nikola Vlahov, David M Gay, John R P Knight, Rene Jackstadt, Joshua D G Leach, Rachel A Ridgway, Emma R Johnson, Colin Nixon, Ann Hedley, Kathryn Gilroy, William Clark, Sudhir B Malla, Philip D Dunne, Giovanny Rodriguez Blanco, Susan E Critchlow, Agata Mrowinska, Gaurav Malviya, Dmitry Solovyev, Gavin Brown, David Y Lewis, Gillian M Mackay, Douglas Strathdee, Saverio Tardito, Eyal Gottlieb, null null, Zoltan Takats, Simon T Barry, Richard J A Goodwin, Josephine Bunch, Martin Bushell, Andrew D Campbell, Owen James Sansom
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer. Nature genetics 53 (1) (2021)
Reza Shariatgorji, Anna Nilsson, Elva Fridjonsdottir, Nicole Strittmatter, Andreas Dannhorn, Per Svenningsson, Richard J A Goodwin, Luke R Odell, Per E Andren
Spatial visualization of comprehensive brain neurotransmitter systems and neuroactive substances by selective in situ chemical derivatization mass spectrometry imaging. Nature protocols 16 (7) (2021)
Nicola Colclough, Kan Chen, Peter Johnström, Nicole Strittmatter, Yumei Yan, Gail L Wrigley, Magnus Schou, Richard J A Goodwin, Katarina Varnäs, Sally J Adua, Minghui Zhao, Don X Nguyen, Gareth Maglennon, Peter Barton, James Atkinson, Lin Zhang, Annika Janefeldt, Joanne Wilson, Aaron Smith, Akihiro Takano, Ryosuke Arakawa, Mikhail Kondrashov, Jonas Malmquist, Evgeny Revunov, Ana Vazquez-Romero, Mohammad Mahdi Moein, Albert D Windhorst, Natasha A Karp, M Raymond V Finlay, Richard A Ward, James W T Yates, Paul D Smith, Lars Farde, Zack Cheng, Darren A E Cross
Preclinical Comparison of the Blood-brain barrier Permeability of Osimertinib with Other EGFR TKIs. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (1) (2020)
Martijn J Schuijs, Shaun Png, Arianne C Richard, Anastasia Tsyben, Gregory Hamm, Julie Stockis, Celine Garcia, Silvain Pinaud, Ashley Nicholls, Xavier Romero Ros, Jing Su, Matthew D Eldridge, Angela Riedel, Eva Mendes Serrao, Hans-Reimer Rodewald, Matthias Mack, Jacqueline D Shields, E Suzanne Cohen, Andrew N J McKenzie, Richard J A Goodwin, Kevin M Brindle, John C Marioni, Timotheus Y F Halim
ILC2-driven innate immune checkpoint mechanism antagonizes NK cell antimetastatic function in the lung. Nature immunology 21 (9) (2020)

Richard J A Goodwin.css-eqlu8i{font-size:small;padding-left:4px;} (Richard Goodwin)

Publication Activity (10 Years)

Top Topics

Top Venues

Richard J A Goodwin (Richard Goodwin)