Kristina Kirschner

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 24

Top Venues

Nature communications

Cancer research communications

Nature aging

Nature medicine

University of Glasgow

University of Edinburgh (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Glasgow Jan 01 2018

United Kingdom

Group leader/ Lead Single Cell Genomics Core Facility :: Institute for Cancer Sciences

University of Glasgow Sep 01 2016 - Feb 28 2018

United Kingdom

Wellcome Trust ISSF Fellow :: Institute for Cancer Sciences

University of Cambridge - Aug 31 2016

United Kingdom

Post-- doctoral Research Fellow :: Haematology

CRUK Cambridge Institute

United Kingdom

Post- doctoral Research Fellow

Education History

University of Edinburgh

United Kingdom

PHD :: Pathology

Publications

Rana Fetit, Alistair Stewart McLaren, Mark White, Megan L Mills, John Falconer, Xabier Cortes-Lavaud, Kathryn L Gilroy, Tamsin R M Lannagan, Rachel A Ridgway, Colin Nixon, Varushka Naiker, Renee Njunge, Cassie J Clarke, Declan Whyte, Kristina Kirschner, Rene Jackstadt, James C Norman, Leo M Carlin, Andrew D Campbell, Owen James Sansom, Colin W Steele
Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils. Cancer research communications 4 (2) (2024)
Rana Fetit, Alistair Stewart McLaren, Mark White, Megan L Mills, John Falconer, Xabier Cortes-Lavaud, Kathryn L Gilroy, Tamsin R M Lannagan, Rachel A Ridgway, Colin Nixon, Varushka Naiker, Renee Njunge, Cassie J Clarke, Declan Whyte, Kristina Kirschner, Rene Jackstadt, James C Norman, Leo M Carlin, Andrew D Campbell, Owen James Sansom, Colin W Steele
Characterising neutrophil subtypes in cancer using scRNA sequencing demonstrates the importance of IL-1β/CXCR2 axis in generation of metastasis specific neutrophils. Cancer research communications (2024)
Rana Fetit, Alistair Stewart McLaren, Mark White, Megan L Mills, John Falconer, Xabier Cortes-Lavaud, Kathryn L Gilroy, Tamsin R M Lannagan, Rachel A Ridgway, Colin Nixon, Varushka Naiker, Renee Njunge, Cassie J Clarke, Declan Whyte, Kristina Kirschner, Rene Jackstadt, James C Norman, Leo M Carlin, Andrew D Campbell, Owen James Sansom, Colin W Steele
Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils. Cancer research communications 4 (2) (2024)
Amy Dawson, Martha M Zarou, Bodhayan Prasad, Joana Bittencourt-Silvestre, Désirée Zerbst, Ekaterini Himonas, Ya-Ching Hsieh, Isabel van Loon, Giovanny Rodriguez Blanco, Angela Ianniciello, Zsombor Kerekes, Vaidehi Krishnan, Puneet Agarwal, Hassan Almasoudi, Laura McCluskey, Lisa E M Hopcroft, Mary T Scott, Pablo Baquero, Karen M Dunn, David Vetrie, Mhairi Copland, Ravi Bhatia, Seth B Coffelt, Sin Tiong Ong, Helen Wheadon, Sara Zanivan, Kristina Kirschner, G Vignir Helgason
Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche. Nature communications 15 (1) (2024)
Rana Fetit, Alistair Stewart McLaren, Mark White, Megan L Mills, John Falconer, Xabier Cortes-Lavaud, Kathryn L Gilroy, Tamsin R M Lannagan, Rachel A Ridgway, Colin Nixon, Varushka Naiker, Renee Njunge, Cassie J Clarke, Declan Whyte, Kristina Kirschner, Rene Jackstadt, James C Norman, Leo M Carlin, Andrew D Campbell, Owen James Sansom, Colin W Steele
Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils. Cancer research communications 4 (2) (2024)
Amy Dawson, Martha M Zarou, Bodhayan Prasad, Joana Bittencourt-Silvestre, Désirée Zerbst, Ekaterini Himonas, Ya-Ching Hsieh, Isabel van Loon, Giovanny Rodriguez Blanco, Angela Ianniciello, Zsombor Kerekes, Vaidehi Krishnan, Puneet Agarwal, Hassan Almasoudi, Laura McCluskey, Lisa E M Hopcroft, Mary T Scott, Pablo Baquero, Karen M Dunn, David Vetrie, Mhairi Copland, Ravi Bhatia, Seth B Coffelt, Sin Tiong Ong, Helen Wheadon, Sara Zanivan, Kristina Kirschner, G Vignir Helgason
Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche. Nature communications 15 (1) (2024)
Amy Dawson, Martha M Zarou, Bodhayan Prasad, Joana Bittencourt-Silvestre, Désirée Zerbst, Ekaterini Himonas, Ya-Ching Hsieh, Isabel van Loon, Giovanny Rodriguez Blanco, Angela Ianniciello, Zsombor Kerekes, Vaidehi Krishnan, Puneet Agarwal, Hassan Almasoudi, Laura McCluskey, Lisa E M Hopcroft, Mary T Scott, Pablo Baquero, Karen M Dunn, David Vetrie, Mhairi Copland, Ravi Bhatia, Seth B Coffelt, Sin Tiong Ong, Helen Wheadon, Sara Zanivan, Kristina Kirschner, G Vignir Helgason
Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche. Nature communications 15 (1) (2024)
Amy Dawson, Martha M Zarou, Bodhayan Prasad, Joana Bittencourt-Silvestre, Désirée Zerbst, Ekaterini Himonas, Ya-Ching Hsieh, Isabel van Loon, Giovanny Rodriguez Blanco, Angela Ianniciello, Zsombor Kerekes, Vaidehi Krishnan, Puneet Agarwal, Hassan Almasoudi, Laura McCluskey, Lisa E M Hopcroft, Mary T Scott, Pablo Baquero, Karen M Dunn, David Vetrie, Mhairi Copland, Ravi Bhatia, Seth B Coffelt, Sin Tiong Ong, Helen Wheadon, Sara Zanivan, Kristina Kirschner, G Vignir Helgason
Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche. Nature communications 15 (1) (2024)
Rana Fetit, Alistair Stewart McLaren, Mark White, Megan L Mills, John Falconer, Xabier Cortes-Lavaud, Kathryn L Gilroy, Tamsin R M Lannagan, Rachel A Ridgway, Colin Nixon, Varushka Naiker, Renee Njunge, Cassie J Clarke, Declan Whyte, Kristina Kirschner, Rene Jackstadt, James C Norman, Leo M Carlin, Andrew D Campbell, Owen James Sansom, Colin W Steele
Characterising neutrophil subtypes in cancer using scRNA sequencing demonstrates the importance of IL-1β/CXCR2 axis in generation of metastasis specific neutrophils. Cancer research communications (2024)
Amy Dawson, Martha M Zarou, Bodhayan Prasad, Joana Bittencourt-Silvestre, Désirée Zerbst, Ekaterini Himonas, Ya-Ching Hsieh, Isabel van Loon, Giovanny Rodriguez Blanco, Angela Ianniciello, Zsombor Kerekes, Vaidehi Krishnan, Puneet Agarwal, Hassan Almasoudi, Laura McCluskey, Lisa E M Hopcroft, Mary T Scott, Pablo Baquero, Karen M Dunn, David Vetrie, Mhairi Copland, Ravi Bhatia, Seth B Coffelt, Sin Tiong Ong, Helen Wheadon, Sara Zanivan, Kristina Kirschner, G Vignir Helgason
Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche. Nature communications 15 (1) (2024)
Richard Burt, Aditi Dey, Ayse Akarca, Hermione Allen, Rodothea Amerikanou, Samantha Atkinson, David Auty, Jenny Chatzigerou, Emily Annie Cutler, Jose Afonso Guerra-Assuncao, Kristina Kirschner, Ruchi Kumari, Jiten Manji, Teresa Marafioti, Juma Ward, Adele K Fielding
Mitochondrial dsRNA from B-ALL cells stimulates mesenchymal stromal cells to become cancer associated fibroblasts. Blood advances (2024)
Eoin Daniel O'Sullivan, Katie J Mylonas, Cuiyan Xin, David P Baird, Cyril Carvalho, Marie-Helena Docherty, Ross Campbell, Kylie P Matchett, Scott H Waddell, Alexander D Walker, Kevin Michael Gallagher, Siyang Jia, Steve Leung, Alexander Laird, Julia Wilflingseder, Michaela Willi, Maximilian Reck, Sarah Finnie, Angela Oliveira Pisco, Sabrina Gordon-Keylock, Alexander Medvinsky, Luke Boulter, Neil Cowan Henderson, Kristina Kirschner, Tamir Chandra, Bryan R Conway, Jeremy Hughes, Laura Denby, Joseph V Bonventre, David A Ferenbach
Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis. Science translational medicine 15 (698) (2023)
Johan Vande Voorde, Rory T Steven, Arafath K Najumudeen, Catriona A Ford, Alex Dexter, Ariadna Gonzalez-Fernandez, Chelsea J Nikula, Yuchen Xiang, Lauren Ford, Stefania Maneta Stavrakaki, Kathryn L Gilroy, Lucas B Zeiger, Kathryn Pennel, Phimmada Hatthakarnkul, Efstathios A Elia, Ammar Nasif, Teresa Murta, Eftychios Manoli, Sam Mason, Michael Gillespie, Tamsin R M Lannagan, Nikola Vlahov, Rachel A Ridgway, Colin Nixon, Alexander Raven, Megan Mills, Dimitris Athineos, Georgios Kanellos, Craig Nourse, David M Gay, Mark Hughes, Amy Burton, Bin Yan, Katherine Sellers, Vincen Wu, Kobe De Ridder, Engy Shokry, Alejandro Huerta Uribe, William Clark, Graeme Clark, Kristina Kirschner, Bernard Thienpont, Vivian Sze Wing Li, Oliver D K Maddocks, Simon T Barry, Richard J A Goodwin, James Macalister Kinross, Joanne Edwards, Mariia O Yuneva, David Sumpton, Zoltán Takáts, Andrew D Campbell, Josephine Bunch, Owen James Sansom
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target. Nature metabolism (2023)
Neil Alistair Robertson, Eric Latorre-Crespo, Maria Terradas Terradas, Jorge Lemos-Portela, Alison C Purcell, Benjamin J Livesey, Robert F Hillary, Lee Murphy, Angie Fawkes, Louise MacGillivray, Mhairi Copland, Riccardo E Marioni, Joseph A Marsh, Sarah E Harris, Simon R Cox, Ian J Deary, Linus J Schumacher, Kristina Kirschner, Tamir Chandra
Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects. Nature medicine 28 (7) (2022)
Chrysa Kapeni, Leslie Nitsche, Alastair M Kilpatrick, Nicola K Wilson, Kankan Xia, Bahar Mirshekar-Syahkal, Vashe Chandrakanthan, Camille Malouf, John E Pimanda, Berthold Göttgens, Kristina Kirschner, Simon R Tomlinson, Katrin Ottersbach
p57Kip2 regulates embryonic blood stem cells by controlling sympathoadrenal progenitor expansion. Blood 140 (5) (2022)
Sarah C Edwards, Ann Hedley, Wilma H M Hoevenaar, Robert Wiesheu, Teresa Glauner, Anna Kilbey, Robin Shaw, Katerina Boufea, Nizar N Batada, Shinya Hatano, Yasunobu Yoshikai, Karen Blyth, Crispin J Miller, Kristina Kirschner, Seth B Coffelt
PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A-producing γδ T cells. The Journal of experimental medicine 220 (2) (2022)
Kosuke Tomimatsu, Dóra Bihary, Ioana Olan, Aled J Parry, Stefan Schoenfelder, Adelyne S L Chan, Guy St C Slater, Yoko Ito, Peter J Rugg-Gunn, Kristina Kirschner, Camino Bermejo-Rodriguez, Tomomi Seko, Hiroyuki Kugoh, Ken Shiraishi, Koji Sayama, Hitoshi Kurumizaka, Peter Fraser, Masako Narita, Shamith A Samarajiwa, Masashi Narita
Locus-specific induction of gene expression from heterochromatin loci during cellular senescence. Nature aging 2 (1) (2021)
Anne-Louise Latif, Ashley Newcombe, Sha Li, Kathryn Gilroy, Neil Alistair Robertson, Xue Lei, Helen J S Stewart, John Cole, Maria Terradas Terradas, Loveena Rishi, Lynn McGarry, Claire McKeeve, Claire Reid, William Clark, Joana Campos, Kristina Kirschner, Andrew Davis, Jonathan Lopez, Jun-Ichi Sakamaki, Jennifer P Morton, Kevin M Ryan, Stephen W G Tait, Sheela A Abraham, Tessa Holyoake, Brian Higgins, Xu Huang, Karen Blyth, Mhairi Copland, Timothy J T Chevassut, Karen Keeshan, Peter D Adams
BRD4-mediated repression of p53 is a target for combination therapy in AML. Nature communications 12 (1) (2021)
Kosuke Tomimatsu, Dóra Bihary, Ioana Olan, Aled J Parry, Stefan Schoenfelder, Adelyne S L Chan, Guy St C Slater, Yoko Ito, Peter J Rugg-Gunn, Kristina Kirschner, Camino Bermejo-Rodriguez, Tomomi Seko, Hiroyuki Kugoh, Ken Shiraishi, Koji Sayama, Hitoshi Kurumizaka, Peter Fraser, Masako Narita, Shamith A Samarajiwa, Masashi Narita
Locus-specific induction of gene expression from heterochromatin loci during cellular senescence. Nature aging 2 (1) (2021)
Ya-Ching Hsieh, Kristina Kirschner, Mhairi Copland
Improving outcomes in chronic myeloid leukemia through harnessing the immunological landscape. Leukemia 35 (5) (2021)
Kosuke Tomimatsu, Dóra Bihary, Ioana Olan, Aled J Parry, Stefan Schoenfelder, Adelyne S L Chan, Guy St C Slater, Yoko Ito, Peter J Rugg-Gunn, Kristina Kirschner, Camino Bermejo-Rodriguez, Tomomi Seko, Hiroyuki Kugoh, Ken Shiraishi, Koji Sayama, Hitoshi Kurumizaka, Peter Fraser, Masako Narita, Shamith A Samarajiwa, Masashi Narita
Locus-specific induction of gene expression from heterochromatin loci during cellular senescence. Nature aging 2 (1) (2021)
Kosuke Tomimatsu, Dóra Bihary, Ioana Olan, Aled J Parry, Stefan Schoenfelder, Adelyne S L Chan, Guy St C Slater, Yoko Ito, Peter J Rugg-Gunn, Kristina Kirschner, Camino Bermejo-Rodriguez, Tomomi Seko, Hiroyuki Kugoh, Ken Shiraishi, Koji Sayama, Hitoshi Kurumizaka, Peter Fraser, Masako Narita, Shamith A Samarajiwa, Masashi Narita
Locus-specific induction of gene expression from heterochromatin loci during cellular senescence. Nature aging 2 (1) (2021)
Dustin J Flanagan, Nalle Pentinmikko, Kalle Luopajärvi, Nicky J Willis, Kathryn Gilroy, Alexander P Raven, Lynn McGarry, Johanna I Englund, Anna T Webb, Sandra Scharaw, Nadia Nasreddin, Michael C Hodder, Rachel A Ridgway, Emma Minnee, Nathalie Sphyris, Ella Gilchrist, Arafath K Najumudeen, Beatrice Romagnolo, Christine Perret, Ann Caroline Williams, Hans Clevers, Pirjo Nummela, Marianne Lähde, Kari Alitalo, Ville Hietakangas, Ann Hedley, William Clark, Colin Nixon, Kristina Kirschner, Edith Yvonne Jones, Ari Ristimäki, Simon J Leedham, Paul V Fish, Jean-Paul Vincent, Pekka Katajisto, Owen James Sansom
NOTUM from Apc-mutant cells biases clonal competition to initiate cancer. Nature 594 (7863) (2021)
Stefano Alivernini, Lucy MacDonald, Aziza Elmesmari, Samuel Finlay, Barbara Tolusso, Maria Rita Gigante, Luca Petricca, Clara Di Mario, Laura Bui, Simone Perniola, Moustafa Attar, Marco Gessi, Anna Laura Fedele, Sabarinadh Chilaka, Domenico Somma, Stephen N Sansom, Andrew Filer, Charles McSharry, Neal L Millar, Kristina Kirschner, Alessandra Nerviani, Myles J Lewis, Costantino Pitzalis, Andrew R Clark, Gianfranco Ferraccioli, Irina A Udalova, Christopher Dominic Buckley, Elisa Gremese, Iain B McInnes, Thomas Dan Otto, Mariola Kurowska-Stolarska
Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis. Nature medicine 26 (8) (2020)

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Publication Activity (10 Years)

Top Topics

Top Venues

Kristina Kirschner