Colin Nixon (C Nixon)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 55

Top Topics

Radical Prostatectomy

Liver Metastases

Top Venues

Science advances

Nature communications

Science signaling

This page only lists publications with an associated author ORCID identifier.

Publications

Savvas Nikolaou, Amelie Juin, Jamie A Whitelaw, Nikki R Paul, Loic Fort, Colin Nixon, Heather J Spence, Sheila Bryson, Laura M Machesky
CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake. eLife 13 (2024)
Rana Fetit, Alistair Stewart McLaren, Mark White, Megan L Mills, John Falconer, Xabier Cortes-Lavaud, Kathryn L Gilroy, Tamsin R M Lannagan, Rachel A Ridgway, Colin Nixon, Varushka Naiker, Renee Njunge, Cassie J Clarke, Declan Whyte, Kristina Kirschner, Rene Jackstadt, James C Norman, Leo M Carlin, Andrew D Campbell, Owen James Sansom, Colin W Steele
Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils. Cancer research communications 4 (2) (2024)
Gaurav Malviya, Tamsin R M Lannagan, Emma Johnson, Agata Mackintosh, Robert Bielik, Adam Peters, Dmitry Soloviev, Manikandan Kadirvel, Rene Jackstadt, Colin Nixon, Kathryn L Gilroy, Andrew D Campbell, Owen James Sansom, David Y Lewis
Noninvasive Stratification of Colon Cancer by Multiplex PET Imaging. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (8) (2024)
Alice Santi, Emily J Kay, Lisa J Neilson, Lynn McGarry, Sergio Lilla, Margaret Mullin, Nikki R Paul, Frédéric Fercoq, Grigorios Koulouras, Giovanny Rodriguez Blanco, Dimitris Athineos, Susan Mason, Mark Hughes, Gemma Thomson, Yann Kieffer, Colin Nixon, Karen Blyth, Fatima Mechta-Grigoriou, Leo M Carlin, Sara R Zanivan
Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function. Science signaling 17 (827) (2024)
Rana Fetit, Alistair Stewart McLaren, Mark White, Megan L Mills, John Falconer, Xabier Cortes-Lavaud, Kathryn L Gilroy, Tamsin R M Lannagan, Rachel A Ridgway, Colin Nixon, Varushka Naiker, Renee Njunge, Cassie J Clarke, Declan Whyte, Kristina Kirschner, Rene Jackstadt, James C Norman, Leo M Carlin, Andrew D Campbell, Owen James Sansom, Colin W Steele
Characterising neutrophil subtypes in cancer using scRNA sequencing demonstrates the importance of IL-1β/CXCR2 axis in generation of metastasis specific neutrophils. Cancer research communications (2024)
Alice Santi, Emily J Kay, Lisa J Neilson, Lynn McGarry, Sergio Lilla, Margaret Mullin, Nikki R Paul, Frédéric Fercoq, Grigorios Koulouras, Giovanny Rodriguez Blanco, Dimitris Athineos, Susan Mason, Mark Hughes, Gemma Thomson, Yann Kieffer, Colin Nixon, Karen Blyth, Fatima Mechta-Grigoriou, Leo M Carlin, Sara R Zanivan
Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function. Science signaling 17 (827) (2024)
Gaurav Malviya, Tamsin R M Lannagan, Emma Johnson, Agata Mackintosh, Robert Bielik, Adam Peters, Dmitry Soloviev, Manikandan Kadirvel, Rene Jackstadt, Colin Nixon, Kathryn L Gilroy, Andrew D Campbell, Owen James Sansom, David Y Lewis
Noninvasive Stratification of Colon Cancer by Multiplex PET Imaging. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Rana Fetit, Alistair Stewart McLaren, Mark White, Megan L Mills, John Falconer, Xabier Cortes-Lavaud, Kathryn L Gilroy, Tamsin R M Lannagan, Rachel A Ridgway, Colin Nixon, Varushka Naiker, Renee Njunge, Cassie J Clarke, Declan Whyte, Kristina Kirschner, Rene Jackstadt, James C Norman, Leo M Carlin, Andrew D Campbell, Owen James Sansom, Colin W Steele
Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils. Cancer research communications 4 (2) (2024)
Alice Santi, Emily J Kay, Lisa J Neilson, Lynn McGarry, Sergio Lilla, Margaret Mullin, Nikki R Paul, Frédéric Fercoq, Grigorios Koulouras, Giovanny Rodriguez Blanco, Dimitris Athineos, Susan Mason, Mark Hughes, Gemma Thomson, Yann Kieffer, Colin Nixon, Karen Blyth, Fatima Mechta-Grigoriou, Leo M Carlin, Sara R Zanivan
Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function. Science signaling 17 (827) (2024)
Savvas Nikolaou, Amelie Juin, Jamie A Whitelaw, Nikki R Paul, Loic Fort, Colin Nixon, Heather J Spence, Sheila Bryson, Laura M Machesky
CYRI-B mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake. eLife 13 (2024)
Antonia M D Churchhouse, Caroline V Billard, Toshiyasu Suzuki, Sebastian Öther-Gee Pohl, Nora J Doleschall, Kevin Donnelly, Colin Nixon, Mark J Arends, Shahida Din, Kathryn Kirkwood, Jair Marques Junior, Alexander von Kriegsheim, Seth B Coffelt, Kevin B Myant
Loss of DOCK2 potentiates Inflammatory Bowel Disease-associated colorectal cancer via immune dysfunction and IFNγ induction of IDO1 expression. Oncogene (2024)
Rana Fetit, Alistair Stewart McLaren, Mark White, Megan L Mills, John Falconer, Xabier Cortes-Lavaud, Kathryn L Gilroy, Tamsin R M Lannagan, Rachel A Ridgway, Colin Nixon, Varushka Naiker, Renee Njunge, Cassie J Clarke, Declan Whyte, Kristina Kirschner, Rene Jackstadt, James C Norman, Leo M Carlin, Andrew D Campbell, Owen James Sansom, Colin W Steele
Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils. Cancer research communications 4 (2) (2024)
Gaurav Malviya, Tamsin R M Lannagan, Emma Johnson, Agata Mackintosh, Robert Bielik, Adam Peters, Dmitry Soloviev, Manikandan Kadirvel, Rene Jackstadt, Colin Nixon, Kathryn L Gilroy, Andrew D Campbell, Owen James Sansom, David Y Lewis
Noninvasive Stratification of Colon Cancer by Multiplex PET Imaging. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (8) (2024)
Savvas Nikolaou, Amelie Juin, Jamie A Whitelaw, Nikki R Paul, Loic Fort, Colin Nixon, Heather J Spence, Sheila Bryson, Laura M Machesky
CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake. eLife 13 (2024)
Savvas Nikolaou, Amelie Juin, Jamie A Whitelaw, Nikki R Paul, Loic Fort, Colin Nixon, Heather J Spence, Sheila Bryson, Laura M Machesky
CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake. eLife 13 (2024)
Rana Fetit, Alistair Stewart McLaren, Mark White, Megan L Mills, John Falconer, Xabier Cortes-Lavaud, Kathryn L Gilroy, Tamsin R M Lannagan, Rachel A Ridgway, Colin Nixon, Varushka Naiker, Renee Njunge, Cassie J Clarke, Declan Whyte, Kristina Kirschner, Rene Jackstadt, James C Norman, Leo M Carlin, Andrew D Campbell, Owen James Sansom, Colin W Steele
Characterising neutrophil subtypes in cancer using scRNA sequencing demonstrates the importance of IL-1β/CXCR2 axis in generation of metastasis specific neutrophils. Cancer research communications (2024)
Savvas Nikolaou, Amelie Juin, Jamie A Whitelaw, Nikki R Paul, Loic Fort, Colin Nixon, Heather J Spence, Sheila Bryson, Laura M Machesky
CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake. eLife 13 (2024)
Gaurav Malviya, Tamsin R M Lannagan, Emma Johnson, Agata Mackintosh, Robert Bielik, Adam Peters, Dmitry Soloviev, Manikandan Kadirvel, Rene Jackstadt, Colin Nixon, Kathryn L Gilroy, Andrew D Campbell, Owen James Sansom, David Y Lewis
Noninvasive Stratification of Colon Cancer by Multiplex PET Imaging. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (8) (2024)
Emma Sandilands, Eva C Freckmann, Erin M Cumming, Álvaro Román-Fernández, Lynn McGarry, Jayanthi Anand, Laura C A Galbraith, Susan Mason, Rachana Patel, Colin Nixon, Jared Cartwright, Hing Y Leung, Karen Blyth, David M Bryant Editor
The small GTPase ARF3 controls invasion modality and metastasis by regulating N-cadherin levels. The Journal of cell biology 222 (4) (2023)
Emma Sandilands, Eva C Freckmann, Erin M Cumming, Álvaro Román-Fernández, Lynn McGarry, Jayanthi Anand, Laura C A Galbraith, Susan Mason, Rachana Patel, Colin Nixon, Jared Cartwright, Hing Y Leung, Karen Blyth, David M Bryant Editor
The small GTPase ARF3 controls invasion modality and metastasis by regulating N-cadherin levels. The Journal of cell biology 222 (4) (2023)
Álvaro Román-Fernández, Mohammed A Mansour, Fernanda G Kugeratski, Jayanthi Anand, Emma Sandilands, Laura C A Galbraith, Kai Rakovic, Eva C Freckmann, Erin M Cumming, Ji Park, Konstantina Nikolatou, Sergio Lilla, Robin Shaw, David Strachan, Susan Mason, Rachana Patel, Lynn McGarry, Archana Katoch, Kirsteen J Campbell, Colin Nixon, Crispin J Miller, Hing Y Leung, John P C Le Quesne, James C Norman, Sara R Zanivan, Karen Blyth, David M Bryant Editor
Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science advances 9 (5) (2023)
Álvaro Román-Fernández, Mohammed A Mansour, Fernanda G Kugeratski, Jayanthi Anand, Emma Sandilands, Laura C A Galbraith, Kai Rakovic, Eva C Freckmann, Erin M Cumming, Ji Park, Konstantina Nikolatou, Sergio Lilla, Robin Shaw, David Strachan, Susan Mason, Rachana Patel, Lynn McGarry, Archana Katoch, Kirsteen J Campbell, Colin Nixon, Crispin J Miller, Hing Y Leung, John P C Le Quesne, James C Norman, Sara R Zanivan, Karen Blyth, David M Bryant Editor
Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science advances 9 (5) (2023)
Álvaro Román-Fernández, Mohammed A Mansour, Fernanda G Kugeratski, Jayanthi Anand, Emma Sandilands, Laura C A Galbraith, Kai Rakovic, Eva C Freckmann, Erin M Cumming, Ji Park, Konstantina Nikolatou, Sergio Lilla, Robin Shaw, David Strachan, Susan Mason, Rachana Patel, Lynn McGarry, Archana Katoch, Kirsteen J Campbell, Colin Nixon, Crispin J Miller, Hing Y Leung, John P C Le Quesne, James C Norman, Sara R Zanivan, Karen Blyth, David M Bryant Editor
Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science advances 9 (5) (2023)
Colin S Wood, Kathryn A F Pennel, Holly Leslie, Assya Legrini, Andrew J Cameron, Lydia Melissourgou-Syka, Jean A Quinn, Hester C van Wyk, Jennifer Hay, Antonia K Roseweir, Colin Nixon, Campbell Stuart Roxburgh, Donald C McMillan, Andrew V Biankin, Owen James Sansom, Paul G Horgan, Joanne Edwards, Colin W Steele, Nigel B Jamieson
Spatially Resolved Transcriptomics Deconvolutes Prognostic Histological Subgroups in Patients with Colorectal Cancer and Synchronous Liver Metastases. Cancer research 83 (8) (2023)
Álvaro Román-Fernández, Mohammed A Mansour, Fernanda G Kugeratski, Jayanthi Anand, Emma Sandilands, Laura C A Galbraith, Kai Rakovic, Eva C Freckmann, Erin M Cumming, Ji Park, Konstantina Nikolatou, Sergio Lilla, Robin Shaw, David Strachan, Susan Mason, Rachana Patel, Lynn McGarry, Archana Katoch, Kirsteen J Campbell, Colin Nixon, Crispin J Miller, Hing Y Leung, John P C Le Quesne, James C Norman, Sara R Zanivan, Karen Blyth, David M Bryant Editor
Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science advances 9 (5) (2023)
Emma Sandilands, Eva C Freckmann, Erin M Cumming, Álvaro Román-Fernández, Lynn McGarry, Jayanthi Anand, Laura C A Galbraith, Susan Mason, Rachana Patel, Colin Nixon, Jared Cartwright, Hing Y Leung, Karen Blyth, David M Bryant Editor
The small GTPase ARF3 controls invasion modality and metastasis by regulating N-cadherin levels. The Journal of cell biology 222 (4) (2023)
Dustin J Flanagan, Raheleh Amirkhah, David F Vincent, Nuray Gunduz, Pauline Gentaz, Patrizia Cammareri, Aoife J McCooey, Amy M B McCorry, Natalie C Fisher, Hayley L Belnoue-Davis, Rachel A Ridgway, Jeroen Lohuis, Joshua D G Leach, Rene Jackstadt, Kathryn Gilroy, Elisa Mariella, Colin Nixon, William Clark, Ann Hedley, Elke K Markert, Douglas Strathdee, Laurent Bartholin, Keara L Redmond, Emma M Kerr, Daniel B Longley, Fiona Ginty, Sanghee Cho, Helen G Coleman, Maurice B Loughrey, Alberto Bardelli, Timothy S Maughan, Andrew D Campbell, Mark Lawler, Simon J Leedham, Simon T Barry, Gareth J Inman, Jacco van Rheenen, Philip David Dunne, Owen James Sansom
Author Correction: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features. Nature communications 14 (1) (2023)
Emma Sandilands, Eva C Freckmann, Erin M Cumming, Álvaro Román-Fernández, Lynn McGarry, Jayanthi Anand, Laura C A Galbraith, Susan Mason, Rachana Patel, Colin Nixon, Jared Cartwright, Hing Y Leung, Karen Blyth, David M Bryant Editor
The small GTPase ARF3 controls invasion modality and metastasis by regulating N-cadherin levels. The Journal of cell biology 222 (4) (2023)
Emma Sandilands, Eva C Freckmann, Erin M Cumming, Álvaro Román-Fernández, Lynn McGarry, Jayanthi Anand, Laura C A Galbraith, Susan Mason, Rachana Patel, Colin Nixon, Jared Cartwright, Hing Y Leung, Karen Blyth, David M Bryant Editor
The small GTPase ARF3 controls invasion modality and metastasis by regulating N-cadherin levels. The Journal of cell biology 222 (4) (2023)
Johan Vande Voorde, Rory T Steven, Arafath K Najumudeen, Catriona A Ford, Alex Dexter, Ariadna Gonzalez-Fernandez, Chelsea J Nikula, Yuchen Xiang, Lauren Ford, Stefania Maneta Stavrakaki, Kathryn L Gilroy, Lucas B Zeiger, Kathryn Pennel, Phimmada Hatthakarnkul, Efstathios A Elia, Ammar Nasif, Teresa Murta, Eftychios Manoli, Sam Mason, Michael Gillespie, Tamsin R M Lannagan, Nikola Vlahov, Rachel A Ridgway, Colin Nixon, Alexander Raven, Megan Mills, Dimitris Athineos, Georgios Kanellos, Craig Nourse, David M Gay, Mark Hughes, Amy Burton, Bin Yan, Katherine Sellers, Vincen Wu, Kobe De Ridder, Engy Shokry, Alejandro Huerta Uribe, William Clark, Graeme Clark, Kristina Kirschner, Bernard Thienpont, Vivian Sze Wing Li, Oliver D K Maddocks, Simon T Barry, Richard J A Goodwin, James Macalister Kinross, Joanne Edwards, Mariia O Yuneva, David Sumpton, Zoltán Takáts, Andrew D Campbell, Josephine Bunch, Owen James Sansom
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target. Nature metabolism (2023)
Álvaro Román-Fernández, Mohammed A Mansour, Fernanda G Kugeratski, Jayanthi Anand, Emma Sandilands, Laura C A Galbraith, Kai Rakovic, Eva C Freckmann, Erin M Cumming, Ji Park, Konstantina Nikolatou, Sergio Lilla, Robin Shaw, David Strachan, Susan Mason, Rachana Patel, Lynn McGarry, Archana Katoch, Kirsteen J Campbell, Colin Nixon, Crispin J Miller, Hing Y Leung, John P C Le Quesne, James C Norman, Sara R Zanivan, Karen Blyth, David M Bryant Editor
Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science advances 9 (5) (2023)
Álvaro Román-Fernández, Mohammed A Mansour, Fernanda G Kugeratski, Jayanthi Anand, Emma Sandilands, Laura C A Galbraith, Kai Rakovic, Eva C Freckmann, Erin M Cumming, Ji Park, Konstantina Nikolatou, Sergio Lilla, Robin Shaw, David Strachan, Susan Mason, Rachana Patel, Lynn McGarry, Archana Katoch, Kirsteen J Campbell, Colin Nixon, Crispin J Miller, Hing Y Leung, John P C Le Quesne, James C Norman, Sara R Zanivan, Karen Blyth, David M Bryant Editor
Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science advances 9 (5) (2023)
Dustin J Flanagan, Raheleh Amirkhah, David F Vincent, Nuray Gunduz, Pauline Gentaz, Patrizia Cammareri, Aoife J McCooey, Amy M B McCorry, Natalie C Fisher, Hayley L Belnoue-Davis, Rachel A Ridgway, Jeroen Lohuis, Joshua D G Leach, Rene Jackstadt, Kathryn Gilroy, Elisa Mariella, Colin Nixon, William Clark, Ann Hedley, Elke K Markert, Douglas Strathdee, Laurent Bartholin, Keara L Redmond, Emma M Kerr, Daniel B Longley, Fiona Ginty, Sanghee Cho, Helen G Coleman, Maurice B Loughrey, Alberto Bardelli, Timothy S Maughan, Andrew D Campbell, Mark Lawler, Simon J Leedham, Simon T Barry, Gareth J Inman, Jacco van Rheenen, Philip David Dunne, Owen James Sansom
Author Correction: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features. Nature communications 14 (1) (2023)
Alice D Baudot, Victoria Min-Yi Wang, Josh D Leach, Jim O'Prey, Jaclyn S Long, Viola Paulus-Hock, Sergio Lilla, David M Thomson, John Greenhorn, Farah Ghaffar, Colin Nixon, Miep H Helfrich, Douglas Strathdee, Judith A Pratt, Francesco Marchesi, Sara Zanivan, Kevin M Ryan
Glycan degradation promotes macroautophagy. Proceedings of the National Academy of Sciences of the United States of America 119 (26) (2022)
Anna L Koessinger, Catherine Cloix, Dominik Koessinger, Dieter Henrik Heiland, Florian J Bock, Karen Strathdee, Kevin Kinch, Laura Martínez-Escardó, Nikki R Paul, Colin Nixon, Gaurav Malviya, Mark R Jackson, Kirsteen J Campbell, Katrina Stevenson, Sandeep Davis, Yassmin Elmasry, Asma Ahmed, Jim O'Prey, Gabriel Ichim, Oliver Schnell, William Stewart, Karen Blyth, Kevin M Ryan, Anthony J Chalmers, James C Norman, Stephen W G Tait
Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics. Cell death and differentiation 29 (10) (2022)
Timothy J Humpton, Andreas K Hock, Christos Kiourtis, Marco De Donatis, Frédéric Fercoq, Colin Nixon, Sheila Bryson, Douglas Strathdee, Leo M Carlin, Thomas G Bird, Karen Blyth, Karen H Vousden
A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo. Science signaling 15 (720) (2022)
Dustin J Flanagan, Raheleh Amirkhah, David F Vincent, Nuray Gundaz, Pauline Gentaz, Patrizia Cammareri, Aoife J McCooey, Amy M B McCorry, Natalie C Fisher, Hayley L Belnoue-Davis, Rachel A Ridgway, Jeroen Lohuis, Joshua D G Leach, Rene Jackstadt, Kathryn Gilroy, Elisa Mariella, Colin Nixon, William Clark, Ann Hedley, Elke K Markert, Douglas Strathdee, Laurent Bartholin, Keara L Redmond, Emma M Kerr, Daniel B Longley, Fiona Ginty, Sanghee Cho, Helen G Coleman, Maurice B Loughrey, Alberto Bardelli, Timothy S Maughan, Andrew D Campbell, Mark Lawler, Simon J Leedham, Simon T Barry, Gareth J Inman, Jacco van Rheenen, Philip David Dunne, Owen James Sansom
Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features. Nature communications 13 (1) (2022)
Victor H Villar, Maria Francesca Allega, Ruhi S Deshmukh, Tobias Ackermann, Mark A Nakasone, Johan Vande Voorde, Thomas M Drake, Janina Oetjen, Algernon Bloom, Colin Nixon, Miryam Müller, Stephanie May, Ee Hong Tan, Lars Vereecke, Maude Jans, Gillian Blancke, Daniel J Murphy, Danny T Huang, David Y Lewis, Thomas G Bird, Owen James Sansom, Karen Blyth, David Sumpton, Saverio Tardito
Hepatic glutamine synthetase controls N 5 -methylglutamine in homeostasis and cancer. Nature chemical biology (2022)
Arnaud Blomme, Coralie Peter, Ernest Mui, Giovanny Rodriguez Blanco, Ning An, Louise M Mason, Lauren E Jamieson, Grace H McGregor, Sergio Lilla, Chara Ntala, Rachana Patel, Marc Thiry, Sonia H Y Kung, Marine Leclercq, Catriona A Ford, Linda K Rushworth, David J McGarry, Susan Mason, Peter Repiscak, Colin Nixon, Mark J Salji, Elke Markert, Gillian M MacKay, Jurre J Kamphorst, Duncan Graham, Karen Faulds, Ladan Fazli, Martin E Gleave, Edward Avezov, Joanne Edwards, Huabing Yin, David Sumpton, Karen Blyth, Pierre Close, Daniel J Murphy, Sara R Zanivan, Hing Y Leung
THEM6-mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer. EMBO molecular medicine 14 (3) (2022)
Arafath K Najumudeen, Fatih Ceteci, Sigrid K Fey, Gregory Hamm, Rory T Steven, Holly Hall, Chelsea J Nikula, Alex Dexter, Teresa Murta, Alan M Race, David Sumpton, Nikola Vlahov, David M Gay, John R P Knight, Rene Jackstadt, Joshua D G Leach, Rachel A Ridgway, Emma R Johnson, Colin Nixon, Ann Hedley, Kathryn Gilroy, William Clark, Sudhir B Malla, Philip D Dunne, Giovanny Rodriguez Blanco, Susan E Critchlow, Agata Mrowinska, Gaurav Malviya, Dmitry Solovyev, Gavin Brown, David Y Lewis, Gillian M Mackay, Douglas Strathdee, Saverio Tardito, Eyal Gottlieb, null null, Zoltan Takats, Simon T Barry, Richard J A Goodwin, Josephine Bunch, Martin Bushell, Andrew D Campbell, Owen James Sansom
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer. Nature genetics 53 (1) (2021)
Valentin J A Barthet, Martina Brucoli, Marcus J G W Ladds, Christoph Nössing, Christos Kiourtis, Alice D Baudot, James O'Prey, Barbara Zunino, Miryam Müller, Stephanie May, Colin Nixon, Jaclyn S Long, Thomas G Bird, Kevin M Ryan
Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver. Science advances 7 (23) (2021)
Rafael S Martinez, Mark J Salji, Linda Rushworth, Chara Ntala, Giovanny Rodriguez Blanco, Ann Hedley, William Clark, Paul Peixoto, Eric Hervouet, Elodie Renaude, Sonia H Y Kung, Laura C A Galbraith, Colin Nixon, Sergio Lilla, Gillian M MacKay, Ladan Fazli, Luke Gaughan, David Sumpton, Martin E Gleave, Sara R Zanivan, Arnaud Blomme, Hing Y Leung
SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer. Cancer research 81 (13) (2021)
Victoria Gudiño, Sebastian Öther-Gee Pohl, Caroline V Billard, Patrizia Cammareri, Alfonso Bolado, Stuart Aitken, David Stevenson, Adam E Hall, Mark Agostino, John Cassidy, Colin Nixon, Alexander von Kriegsheim, Paz Freile, Linda Popplewell, George Dickson, Laura Murphy, Ann Wheeler, Malcolm Dunlop, Farhat Din, Douglas Strathdee, Owen James Sansom, Kevin B Myant
RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways. Nature communications 12 (1) (2021)
Timothy J Humpton, Holly Hall, Christos Kiourtis, Colin Nixon, William Clark, Ann Hedley, Robin Shaw, Thomas G Bird, Karen Blyth, Karen H Vousden
p53-mediated redox control promotes liver regeneration and maintains liver function in response to CCl4. Cell death and differentiation (2021)
Sarah E Minnis-Lyons, Sofía Ferreira-González, Niya Aleksieva, Tak Yung Man, Victoria L Gadd, Michael J Williams, Rachel V Guest, Wei-Yu Lu, Benjamin J Dwyer, Thomas Jamieson, Colin Nixon, Noémi K M van Hul, Frederic P Lemaigre, John McCafferty, Isabelle A Leclercq, Owen James Sansom, Luke Boulter, Stuart John Forbes
Notch-IGF1 signaling during liver regeneration drives biliary epithelial cell expansion and inhibits hepatocyte differentiation. Science signaling 14 (688) (2021)
Joshua D G Leach, Nikola Vlahov, Petros K Tsantoulis, Rachel A Ridgway, Dustin J Flanagan, Kathryn Gilroy, Nathalie Sphyris, Ester G Vázquez, David F Vincent, William James Faller, Michael C Hodder, Alexander Raven, Sigrid Fey, Arafath K Najumudeen, Douglas Strathdee, Colin Nixon, Mark Hughes, William Clark, Robin Shaw, null null, Sander R van Hooff, David J Huels, Jan Paul Medema, Simon T Barry, Margaret C Frame, Asier Unciti-Broceta, Simon J Leedham, Gareth J Inman, Rene Jackstadt, Barry James Thompson, Andrew D Campbell, Sabine Tejpar, Owen James Sansom
Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis. Nature communications 12 (1) (2021)
Angela Ianniciello, Martha M Zarou, Kevin M Rattigan, Mary T Scott, Amy Dawson, Karen M Dunn, Zuzana Brabcova, Eric R Kalkman, Colin Nixon, Alison M Michie, Mhairi Copland, David Vetrie, Martin Ambler, Barbara Saxty, G Vignir Helgason
ULK1 inhibition promotes oxidative stress-induced differentiation and sensitizes leukemic stem cells to targeted therapy. Science translational medicine 13 (613) (2021)
Mathias T Rosenfeldt, Jim O'Prey, Colin R Lindsay, Colin Nixon, Sabine Roth, Owen James Sansom, Kevin M Ryan
Loss of autophagy affects melanoma development in a manner dependent on PTEN status. Cell death and differentiation 28 (4) (2021)
Dustin J Flanagan, Nalle Pentinmikko, Kalle Luopajärvi, Nicky J Willis, Kathryn Gilroy, Alexander P Raven, Lynn McGarry, Johanna I Englund, Anna T Webb, Sandra Scharaw, Nadia Nasreddin, Michael C Hodder, Rachel A Ridgway, Emma Minnee, Nathalie Sphyris, Ella Gilchrist, Arafath K Najumudeen, Beatrice Romagnolo, Christine Perret, Ann Caroline Williams, Hans Clevers, Pirjo Nummela, Marianne Lähde, Kari Alitalo, Ville Hietakangas, Ann Hedley, William Clark, Colin Nixon, Kristina Kirschner, Edith Yvonne Jones, Ari Ristimäki, Simon J Leedham, Paul V Fish, Jean-Paul Vincent, Pekka Katajisto, Owen James Sansom
NOTUM from Apc-mutant cells biases clonal competition to initiate cancer. Nature 594 (7863) (2021)
K A Pickering, K Gilroy, J W Cassidy, S K Fey, Arafath K Najumudeen, Lucas B Zeiger, D F Vincent, David M Gay, J Johansson, R P Fordham, B Miller, W Clark, A Hedley, E B Unal, C Kiel, E McGhee, Laura M Machesky, Colin Nixon, Anna-Karin Johnsson, M Bain, Douglas Strathdee, S R van Hoof, J P Medema, Kurt I Anderson, S M Brachmann, V M Stucke, Angeliki Malliri, M Drysdale, Martin Turner, Luis Serrano, Kevin B Myant, Andrew D Campbell, Owen James Sansom
A RAC-GEF network critical for early intestinal tumourigenesis. Nature communications 12 (1) (2021)
Jack Leslie, Marina García Macia, Saimir Luli, Julie C Worrell, William J Reilly, Hannah L Paish, Amber Knox, Ben S Barksby, Lucy M Gee, Marco Y W Zaki, Amy L Collins, Rachel A Burgoyne, Rainie Cameron, Charlotte Bragg, Xin Xu, Git W Chung, Colin D A Brown, Andrew D Blanchard, Carmel B Nanthakumar, Morten Karsdal, Stuart M Robinson, Derek M Manas, Gourab Sen, Jeremy French, Steven A White, Sandra Murphy, Matthias Trost, Johannes L Zakrzewski, Ulf Klein, Robert F Schwabe, Ingmar Mederacke, Colin Nixon, Thomas G Bird, Laure-Anne Teuwen, Luc Schoonjans, Peter Carmeliet, Jelena Mann, Andrew J Fisher, Neil S Sheerin, Lee A Borthwick, Derek A Mann, Fiona Oakley
Author Correction: c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis. Nature metabolism (2020)
Jack Leslie, Marina García Macia, Saimir Luli, Julie C Worrell, William J Reilly, Hannah L Paish, Amber Knox, Ben S Barksby, Lucy M Gee, Marco Y W Zaki, Amy L Collins, Rachel A Burgoyne, Rainie Cameron, Charlotte Bragg, Xin Xu, Git W Chung, Colin D A Brown, Andrew D Blanchard, Carmel B Nanthakumar, Morten Karsdal, Stuart M Robinson, Derek M Manas, Gourab Sen, Jeremy French, Steven A White, Sandra Murphy, Matthias Trost, Johannes L Zakrzewski, Ulf Klein, Robert F Schwabe, Ingmar Mederacke, Colin Nixon, Thomas G Bird, Laure-Anne Teuwen, Luc Schoonjans, Peter Carmeliet, Jelena Mann, Andrew J Fisher, Neil S Sheerin, Lee A Borthwick, Derek A Mann, Fiona Oakley
c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis. Nature metabolism 2 (11) (2020)
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