Ronald T Raines

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 94

Top Venues

ACS chemical biology

Journal of the American Chemical Society

The Journal of organic chemistry

Bioconjugate chemistry

University of Wisconsin Madison

Harvard University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Wisconsin Madison

United States

Professor Emeritus

Massachusetts Institute of Technology

United States

Professor :: Chemistry

University of Wisconsin Madison

United States

Professor :: Biochemistry and Chemistry

University of California San Francisco

United States

Postdoctorate :: Biochemistry and Biophysics

Education History

Harvard University

United States

PHD :: Chemistry

Publications

Gyeongjin Park, Evans C Wralstad, Noelia Faginas Lago, Kevin Qian, Ronald T Raines, Giovanni Bistoni, Christopher C Cummins
Pentaphosphorylation via the Anhydride of Dihydrogen Pentametaphosphate: Access to Nucleoside Hexa- and Heptaphosphates and Study of Their Interaction with Ribonuclease A. ACS central science 10 (7) (2024)
Gyeongjin Park, Evans C Wralstad, Noelia Faginas Lago, Kevin Qian, Ronald T Raines, Giovanni Bistoni, Christopher C Cummins
Pentaphosphorylation via the Anhydride of Dihydrogen Pentametaphosphate: Access to Nucleoside Hexa- and Heptaphosphates and Study of Their Interaction with Ribonuclease A. ACS central science 10 (7) (2024)
JoLynn B Giancola, Jonathan B Grimm, Joomyung V Jun, Yana D Petri, Luke D Lavis, Ronald T Raines
Evaluation of the Cytosolic Uptake of HaloTag Using a pH-Sensitive Dye. ACS chemical biology 19 (4) (2024)
Brian J Levandowski, Brian J Graham, Nile S Abularrage, Ronald T Raines
Taming the 1,5-sigmatropic shift across protonated spirocyclic 4 H -pyrazoles. Journal of physical organic chemistry 37 (9) (2024)
Yana D Petri, Forrest G FitzGerald, Ronald T Raines
Chemoselective Reagents for the Traceless Bioreversible Modification of Native Proteins. Bioconjugate chemistry (2024)
Jinyi Yang, Yifan Quan, Yifu Ouyang, Kong Ooi Tan, Ralph T Weber, Robert G Griffin, Ronald T Raines
Peptidic "Molecular Beacon" for Collagen. Biomacromolecules (2024)
Aniekan Okon, Jinyi Yang, JoLynn B Giancola, Oscar J Molina, Jessica Sayers, Keith M Cheah, Yanfeng Li, Eric R Strieter, Ronald T Raines
Facile Access to Branched Multispecific Proteins. Bioconjugate chemistry (2024)
Brian J Levandowski, Brian J Graham, Kendall N Houk, Ronald T Raines
Click Organocatalysis: Acceleration of Azide-Alkyne Cycloadditions with Mutually Orthogonal Click Reactions. The Journal of organic chemistry 89 (4) (2024)
Aniekan Okon, Jinyi Yang, JoLynn B Giancola, Oscar J Molina, Jessica Sayers, Keith M Cheah, Yanfeng Li, Eric R Strieter, Ronald T Raines
Facile Access to Branched Multispecific Proteins. Bioconjugate chemistry 35 (7) (2024)
Brian J Levandowski, Brian J Graham, Nile S Abularrage, Ronald T Raines
Taming the 1,5-sigmatropic shift across protonated spirocyclic 4 H -pyrazoles. Journal of physical organic chemistry 37 (9) (2024)
Evans C Wralstad, Ronald T Raines
Sensitive detection of SARS-CoV-2 main protease 3CL pro with an engineered ribonuclease zymogen. Protein science : a publication of the Protein Society 33 (4) (2024)
Aniekan Okon, Jinyi Yang, JoLynn B Giancola, Oscar J Molina, Jessica Sayers, Keith M Cheah, Yanfeng Li, Eric R Strieter, Ronald T Raines
Facile Access to Branched Multispecific Proteins. Bioconjugate chemistry 35 (7) (2024)
Brian J Levandowski, Brian J Graham, Kendall N Houk, Ronald T Raines
Click Organocatalysis: Acceleration of Azide-Alkyne Cycloadditions with Mutually Orthogonal Click Reactions. The Journal of organic chemistry 89 (4) (2024)
Clair S Gutierrez, Alia A Kassim, Benjamin D Gutierrez, Ronald T Raines
Sitetack: A Deep Learning Model that Improves PTM Prediction by Using Known PTMs. bioRxiv : the preprint server for biology (2024)
JoLynn B Giancola, Jonathan B Grimm, Joomyung V Jun, Yana D Petri, Luke D Lavis, Ronald T Raines
Evaluation of the Cytosolic Uptake of HaloTag Using a pH-Sensitive Dye. ACS chemical biology 19 (4) (2024)
Brian J Levandowski, Brian J Graham, Kendall N Houk, Ronald T Raines
Click Organocatalysis: Acceleration of Azide-Alkyne Cycloadditions with Mutually Orthogonal Click Reactions. The Journal of organic chemistry (2024)
Evans C Wralstad, Ronald T Raines
Sensitive detection of SARS-CoV-2 main protease 3CL pro with an engineered ribonuclease zymogen. Protein science : a publication of the Protein Society 33 (4) (2024)
Brian J Levandowski, Brian J Graham, Kendall N Houk, Ronald T Raines
Click Organocatalysis: Acceleration of Azide-Alkyne Cycloadditions with Mutually Orthogonal Click Reactions. The Journal of organic chemistry 89 (4) (2024)
Aniekan Okon, Jinyi Yang, JoLynn B Giancola, Oscar J Molina, Jessica Sayers, Keith M Cheah, Yanfeng Li, Eric R Strieter, Ronald T Raines
Facile Access to Branched Multispecific Proteins. Bioconjugate chemistry 35 (7) (2024)
Brian J Levandowski, Brian J Graham, Nile S Abularrage, Ronald T Raines
Taming the 1,5-sigmatropic shift across protonated spirocyclic 4 H -pyrazoles. Journal of physical organic chemistry 37 (9) (2024)
JoLynn B Giancola, Jonathan B Grimm, Joomyung V Jun, Yana D Petri, Luke D Lavis, Ronald T Raines
Evaluation of the Cytosolic Uptake of HaloTag Using a pH-Sensitive Dye. ACS chemical biology 19 (4) (2024)
JoLynn B Giancola, Jonathan B Grimm, Joomyung V Jun, Yana D Petri, Luke D Lavis, Ronald T Raines
Evaluation of the Cytosolic Uptake of HaloTag Using a pH-Sensitive Dye. ACS chemical biology 19 (4) (2024)
JoLynn B Giancola, Ronald T Raines
Endosomolytic Peptides Enable the Cellular Delivery of Peptide Nucleic Acids. bioRxiv : the preprint server for biology (2024)
JoLynn B Giancola, Jonathan B Grimm, Joomyung V Jun, Yana D Petri, Luke D Lavis, Ronald T Raines
Evaluation of the Cytosolic Uptake of HaloTag Using a pH-Sensitive Dye. ACS chemical biology (2024)
JoLynn B Giancola, Jonathan B Grimm, Joomyung V Jun, Yana D Petri, Luke D Lavis, Ronald T Raines
Evaluation of the Cytosolic Uptake of HaloTag Using a pH-Sensitive Dye. ACS chemical biology 19 (4) (2024)
Evans C Wralstad, Ronald T Raines
Sensitive detection of SARS-CoV-2 main protease 3CL pro with an engineered ribonuclease zymogen. Protein science : a publication of the Protein Society 33 (4) (2024)
JoLynn B Giancola, Jonathan B Grimm, Joomyung V Jun, Yana D Petri, Luke D Lavis, Ronald T Raines
Evaluation of the Cytosolic Uptake of HaloTag Using a pH-Sensitive Dye. ACS chemical biology 19 (4) (2024)
Lindsey O Calabretta, Yana D Petri, Ronald T Raines
Fluorescent Guanidinium-Azacarbazole for Oxoanion Binding in Water. The Journal of organic chemistry (2023)
Brian J Graham, Ian W Windsor, Ronald T Raines
Inhibition of HIV-1 Protease by a Boronic Acid with High Oxidative Stability. ACS medicinal chemistry letters 14 (2) (2023)
Nile S Abularrage, Brian J Levandowski, JoLynn B Giancola, Brian J Graham, Ronald T Raines
Bioorthogonal 4 H -pyrazole "click" reagents. Chemical communications (Cambridge, England) (2023)
I Caglar Tanrikulu, Lianna Dang, Lekha Nelavelli, Aubrey J Ellison, Bradley D Olsen, Song Jin, Ronald T Raines
Synthetic Collagen Hydrogels through Symmetric Self-Assembly of Small Peptides. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2023)
Evans C Wralstad, Jessica Sayers, Ronald T Raines
Bayesian Inference Elucidates the Catalytic Competency of the SARS-CoV-2 Main Protease 3CL pro . Analytical chemistry (2023)
Brian J Graham, Ian W Windsor, Ronald T Raines
Inhibition of HIV-1 Protease by a Boronic Acid with High Oxidative Stability. ACS medicinal chemistry letters 14 (2) (2023)
Isabella M Borgula, Sergey Shuvaev, Eric Abston, Nicholas J Rotile, Jonah Weigand-Whittier, Iris Yuwen Zhou, Peter Caravan, Ronald T Raines
Detection of Pulmonary Fibrosis with a Collagen-Mimetic Peptide. ACS sensors (2023)
Joomyung V Jun, Yana D Petri, Lucas W Erickson, Ronald T Raines
Modular Diazo Compound for the Bioreversible Late-Stage Modification of Proteins. Journal of the American Chemical Society (2023)
Lindsey O Calabretta, Jinyi Yang, Ronald T Raines
Nα-Methylation of arginine: Implications for cell-penetrating peptides. Journal of peptide science : an official publication of the European Peptide Society (2022)
Brian J Levandowski, Nile S Abularrage, Ronald T Raines
Spirocyclization enhances the Diels-Alder reactivities of geminally substituted cyclopentadienes and 4 H -pyrazoles. Journal of physical organic chemistry 36 (4) (2022)
Brian J Levandowski, Nile S Abularrage, Ronald T Raines
Spirocyclization enhances the Diels-Alder reactivities of geminally substituted cyclopentadienes and 4 H -pyrazoles. Journal of physical organic chemistry 36 (4) (2022)
Sayani Chattopadhyay, Leandro B C Teixeira, Laura L Kiessling, Jonathan F McAnulty, Ronald T Raines
Bifunctional Peptide that Anneals to Damaged Collagen and Clusters TGF-β Receptors Enhances Wound Healing. ACS chemical biology 17 (2) (2022)
Keith M Cheah, Joomyung V Jun, K Dane Wittrup, Ronald T Raines
Host-Guest Complexation by β-Cyclodextrin Enhances the Solubility of an Esterified Protein. Molecular pharmaceutics 19 (11) (2022)
Brian J Levandowski, Nile S Abularrage, Ronald T Raines
Spirocyclization enhances the Diels-Alder reactivities of geminally substituted cyclopentadienes and 4 H -pyrazoles. Journal of physical organic chemistry 36 (4) (2022)
Brian J Graham, Ronald T Raines
Emergent Organoboron Acid Catalysts. The Journal of organic chemistry (2022)
Linus B Boll, Ronald T Raines
Context-Dependence of the Reactivity of Cysteine and Lysine Residues. Chembiochem : a European journal of chemical biology 23 (14) (2022)
Lindsey O Calabretta, Jinyi Yang, Ronald T Raines
N α -Methylation of arginine: Implications for cell-penetrating peptides. Journal of peptide science : an official publication of the European Peptide Society (2022)
Joomyung V Jun, Ronald T Raines
Two-Step Synthesis of α-Aryl-α-diazoamides as Modular Bioreversible Labels. Organic letters 23 (8) (2021)
Brian J Levandowski, Ronald T Raines
Click Chemistry with Cyclopentadiene. Chemical reviews 121 (12) (2021)
Emily R Garnett, Ronald T Raines
Emerging biological functions of ribonuclease 1 and angiogenin. Critical reviews in biochemistry and molecular biology (2021)
Kenton J Hetrick, Miguel A Aguilar Ramos, Ronald T Raines
Endogenous Enzymes Enable Antimicrobial Activity. ACS chemical biology 16 (5) (2021)
Jesús M Dones, Nile S Abularrage, Namrata Khanal, Brian Gold, Ronald T Raines
Acceleration of 1,3-Dipolar Cycloadditions by Integration of Strain and Electronic Tuning. Journal of the American Chemical Society 143 (25) (2021)
Ian W Windsor, Dawn M Dudley, David H O'Connor, Ronald T Raines
Ribonuclease zymogen induces cytotoxicity upon HIV-1 infection. AIDS research and therapy 18 (1) (2021)
Brian J Graham, Ian W Windsor, Brian Gold, Ronald T Raines
Boronic acid with high oxidative stability and utility in biological contexts. Proceedings of the National Academy of Sciences of the United States of America 118 (10) (2021)
Caitlin M McMahon, Christine R Isabella, Ian W Windsor, Paul Kosma, Ronald T Raines, Laura L Kiessling
Stereoelectronic Effects Impact Glycan Recognition. Journal of the American Chemical Society 142 (5) (2020)
Alexandra B Schroeder, Aos Karim, Edgar Ocotl, Jesús M Dones, Jenu V Chacko, Aiping Liu, Ronald T Raines, Angela L F Gibson, Kevin W Eliceiri
Optical imaging of collagen fiber damage to assess thermally injured human skin. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 28 (6) (2020)
I Caglar Tanrikulu, William M Westler, Aubrey J Ellison, John L Markley, Ronald T Raines
Templated Collagen "Double Helices" Maintain Their Structure. Journal of the American Chemical Society 142 (3) (2020)
Brian J Levandowski, Nile S Abularrage, Ronald T Raines
Differential Effects of Nitrogen Substitution in 5- and 6-Membered Aromatic Motifs. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (41) (2020)
Brian J Levandowski, Nile S Abularrage, Ronald T Raines
Differential Effects of Nitrogen Substitution in 5- and 6-Membered Aromatic Motifs. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (41) (2020)
Aubrey J Ellison, Felix Dempwolff, Daniel B Kearns, Ronald T Raines
Role for Cell-Surface Collagen of Streptococcus pyogenes in Infections. ACS infectious diseases 6 (7) (2020)
Chelcie H Eller, Ronald T Raines
Antimicrobial Synergy of a Ribonuclease and a Peptide Secreted by Human Cells. ACS infectious diseases 6 (11) (2020)
Aubrey J Ellison, I Caglar Tanrikulu, Jesús M Dones, Ronald T Raines
Cyclic Peptide Mimetic of Damaged Collagen. Biomacromolecules 21 (4) (2020)
Henry R Kilgore, Andrew P Latham, Valerie T Ressler, Bin Zhang, Ronald T Raines
Structure and Dynamics of N-Glycosylated Human Ribonuclease 1. Biochemistry 59 (34) (2020)
Jane Y Song, Kyriel M Pineault, Jesús M Dones, Ronald T Raines, Deneen M Wellik
Hox genes maintain critical roles in the adult skeleton. Proceedings of the National Academy of Sciences of the United States of America 117 (13) (2020)
Henry R Kilgore, Chase R Olsson, Kyan A D'Angelo, Mohammad Movassaghi, Ronald T Raines
n→π* Interactions Modulate the Disulfide Reduction Potential of Epidithiodiketopiperazines. Journal of the American Chemical Society 142 (35) (2020)
Lindsey Rf Backman, Yolanda Y Huang, Mary C Andorfer, Brian Gold, Ronald T Raines, Emily P Balskus, Catherine L Drennan
Molecular basis for catabolism of the abundant metabolite trans-4-hydroxy-L-proline by a microbial glycyl radical enzyme. eLife 9 (2020)
Yun Hu, Jessica M Roberts, Henry R Kilgore, Amirah S Mat Lani, Ronald T Raines, Jennifer M Schomaker
Triple, Mutually Orthogonal Bioorthogonal Pairs through the Design of Electronically Activated Sulfamate-Containing Cycloalkynes. Journal of the American Chemical Society 142 (44) (2020)
Henry R Kilgore, Ronald T Raines
Disulfide Chromophores Arise from Stereoelectronic Effects. The journal of physical chemistry. B 124 (19) (2020)
Jessica Sayers, Evans C Wralstad, Ronald T Raines
Semisynthesis of Human Ribonuclease-S. Bioconjugate chemistry 32 (1) (2020)
Heemal H Dhanjee, Ivan Buslov, Ian W Windsor, Ronald T Raines, Bradley L Pentelute, Stephen L Buchwald
Palladium-Protein Oxidative Addition Complexes by Amine-Selective Acylation. Journal of the American Chemical Society 142 (51) (2020)
Trish T Hoang, Delinda A Johnson, Ronald T Raines, Jeffrey A Johnson
Angiogenin activates the astrocytic Nrf2/antioxidant-response element pathway and thereby protects murine neurons from oxidative stress. The Journal of biological chemistry 294 (41) (2019)
Eddie L Myers, Michael J Palte, Ronald T Raines
Catalysis of Hydrogen-Deuterium Exchange Reactions by 4-Substituted Proline Derivatives. The Journal of organic chemistry 84 (3) (2019)
Brian J Levandowski, Ronald T Raines, Kendall N Houk
Hyperconjugative π → σ*CF Interactions Stabilize the Enol Form of Perfluorinated Cyclic Keto-Enol Systems. The Journal of organic chemistry 84 (10) (2019)
Ian W Windsor, Crystal J Graff, Ronald T Raines
Circular zymogens of human ribonuclease 1. Protein science : a publication of the Protein Society 28 (9) (2019)
Theresa M Reineke, Ronald T Raines, Vincent M Rotello
Delivery of Proteins and Nucleic Acids: Achievements and Challenges. Bioconjugate chemistry 30 (2) (2019)
Robert W Newberry, Ronald T Raines
Secondary Forces in Protein Folding. ACS chemical biology 14 (8) (2019)
Valerie T Ressler, Ronald T Raines
Consequences of the Endogenous N-Glycosylation of Human Ribonuclease 1. Biochemistry 58 (7) (2019)
Scott M Shepard, Ian W Windsor, Ronald T Raines, Christopher C Cummins
Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent Are Potent Inhibitors of Ribonuclease A. Journal of the American Chemical Society 141 (46) (2019)
Emily R Garnett, Jo E Lomax, Bassem M Mohammed, David Gailani, John P Sheehan, Ronald T Raines
Phenotype of ribonuclease 1 deficiency in mice. RNA (New York, N.Y.) 25 (8) (2019)
Kenton J Hetrick, Miguel A Aguilar Ramos, Ronald T Raines
Terbium(III) Luminescence-Based Assay for Esterase Activity. Analytical chemistry 91 (13) (2019)
Brian J Levandowski, Nile S Abularrage, Kendall N Houk, Ronald T Raines
Hyperconjugative Antiaromaticity Activates 4H-Pyrazoles as Inverse-Electron-Demand Diels-Alder Dienes. Organic letters 21 (20) (2019)
Valerie T Ressler, Kalie A Mix, Ronald T Raines
Esterification Delivers a Functional Enzyme into a Human Cell. ACS chemical biology 14 (4) (2019)
Henry R Kilgore, Ronald T Raines
n→π* Interactions Modulate the Properties of Cysteine Residues and Disulfide Bonds in Proteins. Journal of the American Chemical Society 140 (50) (2018)
Ronald T Raines, Helma Wennemers
Peptides on the Rise. Accounts of chemical research 50 (10) (2018)
James D Vasta, Ronald T Raines
Collagen Prolyl 4-Hydroxylase as a Therapeutic Target. Journal of medicinal chemistry 61 (23) (2018)
Ian W Windsor, Michael J Palte, John C Lukesh, Brian Gold, Katrina T Forest, Ronald T Raines
Sub-picomolar Inhibition of HIV-1 Protease with a Boronic Acid. Journal of the American Chemical Society 140 (43) (2018)
Wen Chyan, Ronald T Raines
Enzyme-Activated Fluorogenic Probes for Live-Cell and in Vivo Imaging. ACS chemical biology 13 (7) (2018)
Ian W Windsor, Brian Gold, Ronald T Raines
An n→π* Interaction in the Bound Substrate of Aspartic Proteases Replicates the Oxyanion Hole. ACS catalysis 9 (2) (2018)
Wen Chyan, Henry R Kilgore, Ronald T Raines
Cytosolic Uptake of Large Monofunctionalized Dextrans. Bioconjugate chemistry 29 (6) (2018)
Sydney P Thomas, Trish T Hoang, Valerie T Ressler, Ronald T Raines
Human angiogenin is a potent cytotoxin in the absence of ribonuclease inhibitor. RNA (New York, N.Y.) 24 (8) (2018)
Thomas P Smith, Ian W Windsor, Katrina T Forest, Ronald T Raines
Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation. Journal of medicinal chemistry 60 (18) (2017)
Kalie A Mix, Jo E Lomax, Ronald T Raines
Cytosolic Delivery of Proteins by Bioreversible Esterification. Journal of the American Chemical Society 139 (41) (2017)
Eileen G Burke, Brian Gold, Trish T Hoang, Ronald T Raines, Jennifer M Schomaker
Fine-Tuning Strain and Electronic Activation of Strain-Promoted 1,3-Dipolar Cycloadditions with Endocyclic Sulfamates in SNO-OCTs. Journal of the American Chemical Society 139 (23) (2017)
Robert W Newberry, Ronald T Raines
The n→π* Interaction. Accounts of chemical research 50 (8) (2017)
Wen Chyan, Henry R Kilgore, Brian Gold, Ronald T Raines
Electronic and Steric Optimization of Fluorogenic Probes for Biomolecular Imaging. The Journal of organic chemistry 82 (8) (2017)
Trish T Hoang, Thomas P Smith, Ronald T Raines
A Boronic Acid Conjugate of Angiogenin that Shows ROS-Responsive Neuroprotective Activity. Angewandte Chemie (International ed. in English) 56 (10) (2017)
James D Vasta, Amit Choudhary, Katrina H Jensen, Nicholas A McGrath, Ronald T Raines
Prolyl 4-Hydroxylase: Substrate Isosteres in Which an (E)- or (Z)-Alkene Replaces the Prolyl Peptide Bond. Biochemistry 56 (1) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Ronald T Raines