Ruth Brenk

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 27

Top Venues

Journal of chemical information and modeling

PloS one

Archiv der Pharmazie

ChemMedChem

Universitet i Bergen

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Universitet i Bergen Aug 15 2015

Norway

Professor :: Department of Biomedicine

Publications

Fahimeh Khorsand, Bengt Erik Haug, Inari Kursula, Nathalie Reuter, Ruth Brenk
Expression and purification of human neutrophil proteinase 3 from insect cells and characterization of ligand binding. PloS one 19 (6) (2024)
Parveen Gartan, Fahimeh Khorsand, Pushpak Mizar, Juha Ilmari Vahokovski, Luis F Cervantes, Bengt Erik Haug, Ruth Brenk, Charles L Brooks Iii, Nathalie Reuter
Investigating Polypharmacology through Targeting Known Human Neutrophil Elastase Inhibitors to Proteinase 3. Journal of chemical information and modeling (2024)
Parveen Gartan, Fahimeh Khorsand, Pushpak Mizar, Juha Ilmari Vahokovski, Luis F Cervantes, Bengt Erik Haug, Ruth Brenk, Charles L Brooks Iii, Nathalie Reuter
Investigating Polypharmacology through Targeting Known Human Neutrophil Elastase Inhibitors to Proteinase 3. Journal of chemical information and modeling 64 (3) (2024)
Xavier Jalencas, Hannes Berg, Ludvik Olai Espeland, Sridhar Sreeramulu, Franziska Kinnen, Christian Richter, Charis Georgiou, Vladyslav Yadrykhins'ky, Edgar Specker, Kristaps Jaudzems, Tanja Miletić, Robert K Harmel, Philip Gribbon, Harald Schwalbe, Ruth Brenk, Aigars Jirgensons, Andrea Zaliani, Jordi Mestres
Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection. RSC medicinal chemistry 15 (4) (2024)
Xavier Jalencas, Hannes Berg, Ludvik Olai Espeland, Sridhar Sreeramulu, Franziska Kinnen, Christian Richter, Charis Georgiou, Vladyslav Yadrykhins'ky, Edgar Specker, Kristaps Jaudzems, Tanja Miletić, Robert K Harmel, Philip Gribbon, Harald Schwalbe, Ruth Brenk, Aigars Jirgensons, Andrea Zaliani, Jordi Mestres
Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection. RSC medicinal chemistry 15 (4) (2024)
Bruna Schuck, Ruth Brenk
On the hunt for metalloenzyme inhibitors: Investigating the presence of metal-coordinating compounds in screening libraries and chemical spaces. Archiv der Pharmazie (2024)
Parveen Gartan, Fahimeh Khorsand, Pushpak Mizar, Juha Ilmari Vahokovski, Luis F Cervantes, Bengt Erik Haug, Ruth Brenk, Charles L Brooks Iii, Nathalie Reuter
Investigating Polypharmacology through Targeting Known Human Neutrophil Elastase Inhibitors to Proteinase 3. Journal of chemical information and modeling 64 (3) (2024)
Parveen Gartan, Fahimeh Khorsand, Pushpak Mizar, Juha Ilmari Vahokovski, Luis F Cervantes, Bengt Erik Haug, Ruth Brenk, Charles L Brooks Iii, Nathalie Reuter
Investigating Polypharmacology through Targeting Known Human Neutrophil Elastase Inhibitors to Proteinase 3. Journal of chemical information and modeling 64 (3) (2024)
Bruna Schuck, Ruth Brenk
On the hunt for metalloenzyme inhibitors: Investigating the presence of metal-coordinating compounds in screening libraries and chemical spaces. Archiv der Pharmazie 357 (4) (2024)
Parveen Gartan, Fahimeh Khorsand, Pushpak Mizar, Juha Ilmari Vahokovski, Luis F Cervantes, Bengt Erik Haug, Ruth Brenk, Charles L Brooks Iii, Nathalie Reuter
Investigating Polypharmacology through Targeting Known Human Neutrophil Elastase Inhibitors to Proteinase 3. Journal of chemical information and modeling 64 (3) (2024)
Bruna Schuck, Ruth Brenk
On the hunt for metalloenzyme inhibitors: Investigating the presence of metal-coordinating compounds in screening libraries and chemical spaces. Archiv der Pharmazie 357 (4) (2024)
Fahimeh Khorsand, Bengt Erik Haug, Inari Kursula, Nathalie Reuter, Ruth Brenk
Expression and purification of human neutrophil proteinase 3 from insect cells and characterization of ligand binding. PloS one 19 (6) (2024)
Parveen Gartan, Fahimeh Khorsand, Pushpak Mizar, Juha Ilmari Vahokovski, Luis F Cervantes, Bengt Erik Haug, Ruth Brenk, Charles L Brooks Iii, Nathalie Reuter
Investigating Polypharmacology through Targeting Known Human Neutrophil Elastase Inhibitors to Proteinase 3. Journal of chemical information and modeling 64 (3) (2024)
Parveen Gartan, Fahimeh Khorsand, Pushpak Mizar, Juha Ilmari Vahokovski, Luis F Cervantes, Bengt Erik Haug, Ruth Brenk, Charles L Brooks Iii, Nathalie Reuter
Investigating Polypharmacology through Targeting Known Human Neutrophil Elastase Inhibitors to Proteinase 3. Journal of chemical information and modeling 64 (3) (2024)
Bruna Schuck, Ruth Brenk
On the hunt for metalloenzyme inhibitors: Investigating the presence of metal-coordinating compounds in screening libraries and chemical spaces. Archiv der Pharmazie 357 (4) (2024)
Fahimeh Khorsand, Bengt Erik Haug, Inari Kursula, Nathalie Reuter, Ruth Brenk
Expression and purification of human neutrophil proteinase 3 from insect cells and characterization of ligand binding. PloS one 19 (6) (2024)
Sebastian Bothe, Petra Hänzelmann, Stephan Böhler, Josef Kehrein, Markus Zehe, Christoph Wiedemann, Ute A Hellmich, Ruth Brenk, Hermann Schindelin, Christoph A Sotriffer
Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97. Communications chemistry 5 (1) (2022)
Sebastian Bothe, Petra Hänzelmann, Stephan Böhler, Josef Kehrein, Markus Zehe, Christoph Wiedemann, Ute A Hellmich, Ruth Brenk, Hermann Schindelin, Christoph A Sotriffer
Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97. Communications chemistry 5 (1) (2022)
Illimar Hugo Rekand, Ruth Brenk
DrugPred_RNA-A Tool for Structure-Based Druggability Predictions for RNA Binding Sites. Journal of chemical information and modeling 61 (8) (2021)
Vipul Panchal, Ruth Brenk
Riboswitches as Drug Targets for Antibiotics. Antibiotics (Basel, Switzerland) 10 (1) (2021)
Vladyslav Yadrykhins'ky, Charis Georgiou, Ruth Brenk
Crystal structure of Pseudomonas aeruginosa FabB C161A, a template for structure-based design for new antibiotics. F1000Research 10 (2021)
Vladyslav Yadrykhins'ky, Charis Georgiou, Ruth Brenk
Crystal structure of Pseudomonas aeruginosa FabB C161A, a template for structure-based design for new antibiotics. F1000Research 10 (2021)
Ludvik Olai Espeland, Charis Georgiou, Raphael Klein, Hemalatha Bhukya, Bengt Erik Haug, Jarl Underhaug, Prathama S Mainkar, Ruth Brenk
An Experimental Toolbox for Structure-Based Hit Discovery for P. aeruginosa FabF, a Promising Target for Antibiotics. ChemMedChem 16 (17) (2021)
Kasper P Lundquist, Vipul Panchal, Charlotte Held Gotfredsen, Ruth Brenk, Mads Hartvig Clausen
Fragment-Based Drug Discovery for RNA Targets. ChemMedChem 16 (17) (2021)
Christian Kersten, Edmond Fleischer, Josef Kehrein, Christoph Borek, Elmar Jaenicke, Christoph A Sotriffer, Ruth Brenk
How To Design Selective Ligands for Highly Conserved Binding Sites: A Case Study Using N-Myristoyltransferases as a Model System. Journal of medicinal chemistry 63 (5) (2019)
Tanja Schirmeister, Thomas Wehler, Christoph Borek, Werner Kiefer, Ruth Brenk, Maria Elena Ortiz-Soto, Jürgen Seibel, Tanja Schirmeister
Identification of a potential allosteric site of Golgi α-mannosidase II using computer-aided drug design. PloS one 14 (5) (2019)
Raphael Klein, Pasquale Linciano, Giuseppe Celenza, Pierangelo Bellio, Sofia Papaioannou, Jesus Blazquez, Laura Cendron, Ruth Brenk, Donatella Tondi
In silico identification and experimental validation of hits active against KPC-2 β-lactamase. PloS one 13 (11) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Ruth Brenk