Kristaps Jaudzems

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 45

Top Venues

Nature communications

International journal of molecular sciences

Molecules (Basel, Switzerland)

RSC medicinal chemistry

University of Latvia

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Latvia Mar 01 2018

Latvia

Associate Professor :: Department of Organic Chemistry

Latvijas Organiskas sintezes instituts Sep 01 2017

Latvia

Senior Researcher, Group Leader :: Department of Physical Organic Chemistry

Institut des Sciences Analytiques Sep 01 2015 - Aug 31 2017

France

Postdoctoral Researcher :: Centre de RMN à Très Hauts Champs

Latvijas Organiskas sintezes instituts - Aug 31 2015

Latvia

Senior Researcher :: Department of Physical Organic Chemistry

Publications

Raitis Bobrovs, Svetlana Terentjeva, Ninni Elise Olafsen, Zilvinas Dambrauskas, Antanas Gulbinas, Toivo Maimets, Indrek Teino, Aigars Jirgensons, Jason Matthews, Kristaps Jaudzems
Discovery and optimisation of pyrazolo[1,5- a ]pyrimidines as aryl hydrocarbon receptor antagonists. RSC medicinal chemistry (2024)
Rakesh Kumar, Tanguy Le Marchand, Laurène Adam, Raitis Bobrovs, Gefei Chen, Jēkabs Fridmanis, Nina Kronqvist, Henrik Biverstål, Kristaps Jaudzems, Jan Johansson, Guido Pintacuda, Axel Abelein
Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain. Nature communications 15 (1) (2024)
Rakesh Kumar, Tanguy Le Marchand, Laurène Adam, Raitis Bobrovs, Gefei Chen, Jēkabs Fridmanis, Nina Kronqvist, Henrik Biverstål, Kristaps Jaudzems, Jan Johansson, Guido Pintacuda, Axel Abelein
Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain. Nature communications 15 (1) (2024)
Rakesh Kumar, Tanguy Le Marchand, Laurène Adam, Raitis Bobrovs, Gefei Chen, Jēkabs Fridmanis, Nina Kronqvist, Henrik Biverstål, Kristaps Jaudzems, Jan Johansson, Guido Pintacuda, Axel Abelein
Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain. Nature communications 15 (1) (2024)
Xavier Jalencas, Hannes Berg, Ludvik Olai Espeland, Sridhar Sreeramulu, Franziska Kinnen, Christian Richter, Charis Georgiou, Vladyslav Yadrykhins'ky, Edgar Specker, Kristaps Jaudzems, Tanja Miletić, Robert K Harmel, Philip Gribbon, Harald Schwalbe, Ruth Brenk, Aigars Jirgensons, Andrea Zaliani, Jordi Mestres
Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection. RSC medicinal chemistry 15 (4) (2024)
Xavier Jalencas, Hannes Berg, Ludvik Olai Espeland, Sridhar Sreeramulu, Franziska Kinnen, Christian Richter, Charis Georgiou, Vladyslav Yadrykhins'ky, Edgar Specker, Kristaps Jaudzems, Tanja Miletić, Robert K Harmel, Philip Gribbon, Harald Schwalbe, Ruth Brenk, Aigars Jirgensons, Andrea Zaliani, Jordi Mestres
Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection. RSC medicinal chemistry 15 (4) (2024)
Rakesh Kumar, Tanguy Le Marchand, Laurène Adam, Raitis Bobrovs, Gefei Chen, Jēkabs Fridmanis, Nina Kronqvist, Henrik Biverstål, Kristaps Jaudzems, Jan Johansson, Guido Pintacuda, Axel Abelein
Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain. Nature communications 15 (1) (2024)
Ruslans Muhamadejevs, Klara Haldimann, Marina Gysin, David Crich, Kristaps Jaudzems, Sven N Hobbie
Experimental Determination of the p K a Values of Clinically Relevant Aminoglycoside Antibiotics: Toward Establishing p K a -Activity Relationships. ACS omega 9 (5) (2024)
Vadims Kovada, Chrislaine Withers-Martinez, Raitis Bobrovs, Hele Na Ce Rule, Edgars Liepins, Solveiga Grinberga, Fiona Hackett, Christine R Collins, Agrita Kreicberga, María Belén Jiménez-Díaz, Iñigo Angulo-Barturen, Dace Rasina, Edgars Suna, Kristaps Jaudzems, Michael J Blackman, Aigars Jirgensons
Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity. Journal of medicinal chemistry (2023)
Olga Bobileva, Raitis Bobrovs, Evelina Elva Sirma, Iveta Kaņepe-Lapsa, Anna L Bula, Liene Patetko, Anna Ramata-Stunda, Solveiga Grinberga, Aigars Jirgensons, Kristaps Jaudzems
3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors. Molecules (Basel, Switzerland) 28 (2) (2023)
Arenida Bartkeviciene, Aldona Jasukaitiene, Inga Zievyte, Darius Stukas, Sandra Ivanauskiene, Daiva Urboniene, Toivo Maimets, Kristaps Jaudzems, Astra Vitkauskiene, Jason Matthews, Zilvinas Dambrauskas, Antanas Gulbinas
Association between AHR Expression and Immune Dysregulation in Pancreatic Ductal Adenocarcinoma: Insights from Comprehensive Immune Profiling of Peripheral Blood Mononuclear Cells. Cancers 15 (18) (2023)
Olga Bobileva, Raitis Bobrovs, Evelina Elva Sirma, Iveta Kaņepe-Lapsa, Anna L Bula, Liene Patetko, Anna Ramata-Stunda, Solveiga Grinberga, Aigars Jirgensons, Kristaps Jaudzems
3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors. Molecules (Basel, Switzerland) 28 (2) (2023)
Olga Bobileva, Raitis Bobrovs, Evelina Elva Sirma, Iveta Kaņepe-Lapsa, Anna L Bula, Liene Patetko, Anna Ramata-Stunda, Solveiga Grinberga, Aigars Jirgensons, Kristaps Jaudzems
3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors. Molecules (Basel, Switzerland) 28 (2) (2023)
Felix Torres, Matthias Bütikofer, Gabriela R Stadler, Alois Renn, Harindranath Kadavath, Raitis Bobrovs, Kristaps Jaudzems, Roland Riek
Ultrafast Fragment Screening Using Photo-Hyperpolarized (CIDNP) NMR. Journal of the American Chemical Society (2023)
Diana Zelencova-Gopejenko, Melita Videja, Aiga Grandane, Linda Pudnika-Okinčica, Anda Sipola, Karlis Vilks, Maija Dambrova, Kristaps Jaudzems, Edgars Liepiņš
Heart-Type Fatty Acid Binding Protein Binds Long-Chain Acylcarnitines and Protects against Lipotoxicity. International journal of molecular sciences 24 (6) (2023)
Diana Zelencova-Gopejenko, Melita Videja, Aiga Grandane, Linda Pudnika-Okinčica, Anda Sipola, Karlis Vilks, Maija Dambrova, Kristaps Jaudzems, Edgars Liepiņš
Heart-Type Fatty Acid Binding Protein Binds Long-Chain Acylcarnitines and Protects against Lipotoxicity. International journal of molecular sciences 24 (6) (2023)
Raitis Bobrovs, Laura Drunka, Iveta Kanepe, Aigars Jirgensons, Amedeo Caflisch, Matteo Salvalaglio, Kristaps Jaudzems
Exploring the Binding Pathway of Novel Nonpeptidomimetic Plasmepsin V Inhibitors. Journal of chemical information and modeling (2023)
Olga Bobileva, Raitis Bobrovs, Evelina Elva Sirma, Iveta Kaņepe-Lapsa, Anna L Bula, Liene Patetko, Anna Ramata-Stunda, Solveiga Grinberga, Aigars Jirgensons, Kristaps Jaudzems
3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors. Molecules (Basel, Switzerland) 28 (2) (2023)
Diana Zelencova-Gopejenko, Melita Videja, Aiga Grandane, Linda Pudnika-Okinčica, Anda Sipola, Karlis Vilks, Maija Dambrova, Kristaps Jaudzems, Edgars Liepiņš
Heart-Type Fatty Acid Binding Protein Binds Long-Chain Acylcarnitines and Protects against Lipotoxicity. International journal of molecular sciences 24 (6) (2023)
Darius Stukas, Aldona Jasukaitiene, Arenida Bartkeviciene, Jason Matthews, Toivo Maimets, Indrek Teino, Kristaps Jaudzems, Antanas Gulbinas, Zilvinas Dambrauskas
Targeting AHR Increases Pancreatic Cancer Cell Sensitivity to Gemcitabine through the ELAVL1-DCK Pathway. International journal of molecular sciences 24 (17) (2023)
Tanguy Le Marchand, Tobias Schubeis, Marta Bonaccorsi, Piotr Paluch, Daniela Lalli, Andrew J Pell, Loren B Andreas, Kristaps Jaudzems, Jan Stanek, Guido Pintacuda
1 H-Detected Biomolecular NMR under Fast Magic-Angle Spinning. Chemical reviews 122 (10) (2022)
Karina Spunde, Brigita Vigante, Unda Nelda Dubova, Anda Sipola, Irena Timofejeva, Anna Zajakina, Jurģis Jansons, Aiva Plotniece, Karlis Pajuste, Arkadij Sobolev, Ruslan Muhamadejev, Kristaps Jaudzems, Gunars Duburs, Tatjana Kozlovska
Design and Synthesis of Hepatitis B Virus (HBV) Capsid Assembly Modulators and Evaluation of Their Activity in Mammalian Cell Model. Pharmaceuticals (Basel, Switzerland) 15 (7) (2022)
Zigmantas Toleikis, Raitis Bobrovs, Agne Janoniene, Alons Lends, Mantas Ziaunys, Ieva Baronaite, Vytautas Petrauskas, Kristine Kitoka, Vytautas Smirnovas, Kristaps Jaudzems
Interactions between S100A9 and Alpha-Synuclein: Insight from NMR Spectroscopy. International journal of molecular sciences 23 (12) (2022)
Diana Zelencova-Gopejenko, Aiga Grandane, Einars Loza, Daina Lola, Anda Sipola, Edgars Liepinsh, Pavel Arsenyan, Kristaps Jaudzems
Binding versus Enzymatic Processing of ε-Trimethyllysine Dioxygenase Substrate Analogues. ACS medicinal chemistry letters 13 (11) (2022)
Alons Lends, Asen Daskalov, Ansis Maleckis, Aline Delamare, Mélanie Berbon, Axelle Grélard, Estelle Morvan, Jayakrishna Shenoy, Antoine Dutour, James Tolchard, Abdelmajid Noubhani, Marie-France Giraud, Corinne Sanchez, Birgit Habenstein, Gilles Guichard, Guillaume Compain, Kristaps Jaudzems, Sven J Saupe, Antoine Loquet
Cell-free synthesis of amyloid fibrils with infectious properties and amenable to sub-milligram magic-angle spinning NMR analysis. Communications biology 5 (1) (2022)
Salima Bahri, Robert Silvers, Brian Michael, Kristaps Jaudzems, Daniela Lalli, Gilles Casano, Olivier Ouari, Anne Lesage, Guido Pintacuda, Sara Linse, Robert G Griffin
1 H detection and dynamic nuclear polarization-enhanced NMR of Aβ 1-42 fibrils. Proceedings of the National Academy of Sciences of the United States of America 119 (1) (2022)
Raitis Bobrovs, Emils Edgars Basens, Laura Drunka, Iveta Kanepe, Sofija Matisone, Karlis Kristofers Velins, Victor Andrianov, Gundars Leitis, Diana Zelencova-Gopejenko, Dace Rasina, Aigars Jirgensons, Kristaps Jaudzems
Exploring Aspartic Protease Inhibitor Binding to Design Selective Antimalarials. Journal of chemical information and modeling 62 (13) (2022)
Tina Arndt, Kristaps Jaudzems, Olga Shilkova, Juanita Francis, Mathias Johansson, Peter R Laity, Cagla Sahin, Urmimala Chatterjee, Nina Kronqvist, Edgar Barajas-Ledesma, Rakesh Kumar, Gefei Chen, Roger Strömberg, Axel Abelein, Maud Langton, Michael Landreh, Andreas Barth, Chris Holland, Jan Johansson, Anna Rising
Spidroin N-terminal domain forms amyloid-like fibril based hydrogels and provides a protein immobilization platform. Nature communications 13 (1) (2022)
Hongshuang Guo, Rakesh Puttreddy, Turkka Salminen, Alons Lends, Kristaps Jaudzems, Hao Zeng, Arri Priimägi
Halogen-bonded shape memory polymers. Nature communications 13 (1) (2022)
Hannes Berg, Maria Alexandra Wirtz Martin, Nadide Altincekic, Islam Alshamleh, Jasleen Kaur Bains, Julius Blechar, Betül Ceylan, Vanessa de Jesus, Karthikeyan Dhamotharan, Christin Fuks, Santosh L Gande, Bruno Hargittay, Katharina F Hohmann, Marie T Hutchison, Sophie Marianne Korn, Robin Krishnathas, Felicitas Kutz, Verena Linhard, Tobias Matzel, Nathalie Meiser, Anna Niesteruk, Dennis J Pyper, Linda Schulte, Sven Trucks, Kamal Azzaoui, Marcel J J Blommers, Yojana Gadiya, Reagon Karki, Andrea Zaliani, Philip Gribbon, Marcius da Silva Almeida, Cristiane Dinis Anobom, Anna L Bula, Matthias Bütikofer, Ícaro Putinhon Caruso, Isabella C Felli, Andrea T Da Poian, Gisele Cardoso de Amorim, Nikolaos K Fourkiotis, Angelo Gallo, Dhiman Ghosh, Francisco Gomes-Neto, Oksana Gorbatyuk, Bing Hao, Vilius Kurauskas, Lauriane Lecoq, Yunfeng Li, Nathane Cunha Mebus-Antunes, Miguel Mompeán, Thais Cristtina Neves-Martins, Martí Ninot-Pedrosa, Anderson S Pinheiro, Letizia Pontoriero, Yulia Pustovalova, Roland Riek, Angus J Robertson, Marie Jose Abi Saad, Miguel Á Treviño, Aikaterini C Tsika, Fabio Ceneviva Lacerda de Almeida, Adriaan Bax, Katherine A Henzler-Wildman, Jeffrey C Hoch, Kristaps Jaudzems, Douglas V Laurents, Julien Orts, Roberta Pierattelli, Georgios A Spyroulias, Elke Duchardt-Ferner, Jan Ferner, Boris Fürtig, Martin Hengesbach, Frank Loehr, Nusrat S Qureshi, Christian Richter, Krishna Saxena, Andreas Schlundt, Sridhar Sreeramulu, Anna Wacker, Julia E Weigand, Julia Wirmer-Bartoschek, Jens Wöhnert, Harald Schwalbe
Comprehensive Fragment Screening of the SARS-CoV-2 Proteome Explores Novel Chemical Space for Drug Development. Angewandte Chemie (International ed. in English) 61 (46) (2022)
Kristaps Jaudzems, Anna Kirsteina, Tobias Schubeis, Gilles Casano, Olivier Ouari, Janis Bogans, Andris Kazaks, Kaspars Tars, Anne Lesage, Guido Pintacuda
Structural Analysis of an Antigen Chemically Coupled on Virus-Like Particles in Vaccine Formulation. Angewandte Chemie (International ed. in English) 60 (23) (2021)
Olga Bobileva, Raitis Bobrovs, Iveta Kaņepe, Liene Patetko, Gints Kalniņš, Mihails Šišovs, Anna L Bula, Solveiga Gri Nberga, Ma Rtiņš Borodušķis, Anna Ramata-Stunda, Nils Rostoks, Aigars Jirgensons, Kaspars Tars, Kristaps Jaudzems
Potent SARS-CoV-2 mRNA Cap Methyltransferase Inhibitors by Bioisosteric Replacement of Methionine in SAM Cosubstrate. ACS medicinal chemistry letters 12 (7) (2021)
Ruslan Muhamadejev, Renate Melngaile, Paula Paegle, Ieva Zibarte, Marina Petrova, Kristaps Jaudzems, Janis Veliks
Residual Solvent Signal of CDCl3 as a qNMR Internal Standard for Application in Organic Chemistry Laboratory. The Journal of organic chemistry 86 (5) (2021)
Nikla Vs U Dris, Kristaps Jaudzems, Gints Smits
Total Synthesis of the Proposed Structure of Uncarialin A. The Journal of organic chemistry 86 (9) (2021)
Zigmantas Toleikis, Mantas Ziaunys, Lina Baranauskienė, Vytautas Petrauskas, Kristaps Jaudzems, Vytautas Smirnovas
S100A9 Alters the Pathway of Alpha-Synuclein Amyloid Aggregation. International journal of molecular sciences 22 (15) (2021)
Jēkabs Fridmanis, Zigmantas Toleikis, Tomas Šneideris, Mantas Ziaunys, Raitis Bobrovs, Vytautas Smirnovas, Kristaps Jaudzems
Aggregation Condition-Structure Relationship of Mouse Prion Protein Fibrils. International journal of molecular sciences 22 (17) (2021)
Raitis Bobrovs, Iveta Kanepe, Nauris Narvaiss, Liene Patetko, Gints Kalnins, Mihails Sisovs, Anna L Bula, Solveiga Grinberga, Martins Boroduskis, Anna Ramata-Stunda, Nils Rostoks, Aigars Jirgensons, Kaspars Tars, Kristaps Jaudzems
Discovery of SARS-CoV-2 Nsp14 and Nsp16 Methyltransferase Inhibitors by High-Throughput Virtual Screening. Pharmaceuticals (Basel, Switzerland) 14 (12) (2021)
Jēkabs Fridmanis, Raitis Bobrovs, Kalvis Brangulis, Kaspars Tārs, Kristaps Jaudzems
Structural and Functional Analysis of BBA03, Borrelia burgdorferi Competitive Advantage Promoting Outer Surface Lipoprotein. Pathogens (Basel, Switzerland) 9 (10) (2020)
Jēkabs Fridmanis, Mārtiņš Otikovs, Kalvis Brangulis, Kaspars Tārs, Kristaps Jaudzems
Solution NMR structure of Borrelia burgdorferi outer surface lipoprotein BBP28, a member of the mlp protein family. Proteins 89 (5) (2020)
Mohammadi Pezhman, A Sesilja Aranko, Christopher P Landowski, Olli Ikkala, Kristaps Jaudzems, Wolfgang Wagermaier, Markus B Linder
Biomimetic composites with enhanced toughening using silk-inspired triblock proteins and aligned nanocellulose reinforcements. Science advances 5 (9) (2019)
Kristaps Jaudzems, Viktorija Kurbatska, Atis Je Kabsons, Raitis Bobrovs, Zhanna Rudevica, Ainars Leonchiks
Targeting Bacterial Sortase A with Covalent Inhibitors: 27 New Starting Points for Structure-Based Hit-to-Lead Optimization. ACS infectious diseases 6 (2) (2019)
Rupal Gupta, Huilan Zhang, Manman Lu, Guang-Jin Hou, Marc Caporini, Melanie Rosay, Werner Maas, Jochem Struppe, Jinwoo Ahn, In-Ja L Byeon, Hartmut Oschkinat, Kristaps Jaudzems, Emeline Barbet-Massin, Lyndon Emsley, Guido Pintacuda, Anne Lesage, Angela M Gronenborn, Tatyana Polenova
Dynamic Nuclear Polarization Magic-Angle Spinning Nuclear Magnetic Resonance Combined with Molecular Dynamics Simulations Permits Detection of Order and Disorder in Viral Assemblies. The journal of physical chemistry. B 123 (24) (2019)
Raitis Bobrovs, Kristaps Jaudzems, Aigars Jirgensons
Exploiting Structural Dynamics To Design Open-Flap Inhibitors of Malarial Aspartic Proteases. Journal of medicinal chemistry 62 (20) (2019)
Martins Otikovs, Marlene Andersson, Qiupin Jia, Kerstin Nordling, Qing Meng, Loren B Andreas, Guido Pintacuda, Jan Johansson, Anna Rising, Kristaps Jaudzems
Degree of Biomimicry of Artificial Spider Silk Spinning Assessed by NMR Spectroscopy. Angewandte Chemie (International ed. in English) 56 (41) (2017)
Nina Kronqvist, Médoune Sarr, Anton Lindqvist, Kerstin Nordling, Martins Otikovs, Luca Venturi, Barbara Pioselli, Pasi Purhonen, Michael Landreh, Henrik Biverstål, Zigmantas Toleikis, Lisa Sjöberg, Carol V Robinson, Nicola Pelizzi, Hans Jörnvall, Hans Hebert, Kristaps Jaudzems, Tore Curstedt, Anna Rising, Jan Johansson
Efficient protein production inspired by how spiders make silk. Nature communications 8 (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Kristaps Jaudzems