Christoph A Sotriffer (Christoph Sotriffer)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 34

Top Topics

Molecular Dynamics Simulations

Protein Protein

Top Venues

ACS chemical biology

Acta crystallographica. Section D, Structural biology

Journal of chemical information and modeling

This page only lists publications with an associated author ORCID identifier.

Publications

Jonathan Vincent Patzke, Florian Sauer, Radhika Karal Nair, Erik Endres, Ewgenij Proschak, Victor Hernandez-Olmos, Christoph A Sotriffer, Caroline Kisker
Structural basis for the bi-specificity of USP25 and USP28 inhibitors. EMBO reports 25 (7) (2024)
Markus Zehe, Josef Kehrein, Curd Schollmayer, Christina Plank, Helena Kovacs, Eduardo Merino Asumendi, Gerhard Bringmann, Clemens Grimm, Christoph A Sotriffer
Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct. ACS chemical biology 19 (2) (2024)
Carina Herbst, Sara Endres, Rebecca Würz, Christoph A Sotriffer
Assessment of fragment docking and scoring with the endothiapepsin model system. Archiv der Pharmazie 357 (6) (2024)
Jonathan Vincent Patzke, Florian Sauer, Radhika Karal Nair, Erik Endres, Ewgenij Proschak, Victor Hernandez-Olmos, Christoph A Sotriffer, Caroline Kisker
Structural basis for the bi-specificity of USP25 and USP28 inhibitors. EMBO reports 25 (7) (2024)
Markus Zehe, Josef Kehrein, Curd Schollmayer, Christina Plank, Helena Kovacs, Eduardo Merino Asumendi, Gerhard Bringmann, Clemens Grimm, Christoph A Sotriffer
Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct. ACS chemical biology 19 (2) (2024)
Jonathan Vincent Patzke, Florian Sauer, Radhika Karal Nair, Erik Endres, Ewgenij Proschak, Victor Hernandez-Olmos, Christoph A Sotriffer, Caroline Kisker
Structural basis for the bi-specificity of USP25 and USP28 inhibitors. EMBO reports (2024)
Markus Zehe, Josef Kehrein, Curd Schollmayer, Christina Plank, Helena Kovacs, Eduardo Merino Asumendi, Gerhard Bringmann, Clemens Grimm, Christoph A Sotriffer
Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct. ACS chemical biology 19 (2) (2024)
Carina Herbst, Sara Endres, Rebecca Würz, Christoph A Sotriffer
Assessment of fragment docking and scoring with the endothiapepsin model system. Archiv der Pharmazie (2024)
Markus Zehe, Josef Kehrein, Curd Schollmayer, Christina Plank, Helena Kovacs, Eduardo Merino Asumendi, Gerhard Bringmann, Clemens Grimm, Christoph A Sotriffer
Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct. ACS chemical biology (2024)
Jonathan Vincent Patzke, Florian Sauer, Radhika Karal Nair, Erik Endres, Ewgenij Proschak, Victor Hernandez-Olmos, Christoph A Sotriffer, Caroline Kisker
Structural basis for the bi-specificity of USP25 and USP28 inhibitors. EMBO reports 25 (7) (2024)
Mathias Diebold, Lars Schönemann, Martin Eilers, Christoph A Sotriffer, Hermann Schindelin
Crystal structure of a covalently linked Aurora-A-MYCN complex. Acta crystallographica. Section D, Structural biology 79 (Pt 1) (2023)
Erik Endres, Natalia Yuan-Chen, Christoph A Sotriffer
MD-Based Assessment of Covalent Inhibitors in Noncovalent Association Complexes: Learning from Cathepsin K as a Test Case. Journal of chemical information and modeling 63 (10) (2023)
Mathias Diebold, Lars Schönemann, Martin Eilers, Christoph A Sotriffer, Hermann Schindelin
Crystal structure of a covalently linked Aurora-A-MYCN complex. Acta crystallographica. Section D, Structural biology 79 (Pt 1) (2023)
Erik Endres, Natalia Yuan-Chen, Christoph A Sotriffer
MD-Based Assessment of Covalent Inhibitors in Noncovalent Association Complexes: Learning from Cathepsin K as a Test Case. Journal of chemical information and modeling (2023)
Erik Endres, Natalia Yuan-Chen, Christoph A Sotriffer
MD-Based Assessment of Covalent Inhibitors in Noncovalent Association Complexes: Learning from Cathepsin K as a Test Case. Journal of chemical information and modeling 63 (10) (2023)
Lukas Hahn, Theresa Zorn, Josef Kehrein, Tobias Kielholz, Anna-Lena Ziegler, Stefan Forster, Benedikt Sochor, Ekaterina S Lisitsyna, Nikita A Durandin, Timo Laaksonen, Vladimir O Aseyev, Christoph A Sotriffer, Kay Saalwächter, Maike Windbergs, Ann-Christin Pöppler, Robert Luxenhofer
Unraveling an Alternative Mechanism in Polymer Self-Assemblies: An Order-Order Transition with Unusual Molecular Interactions between Hydrophilic and Hydrophobic Polymer Blocks. ACS nano (2023)
Josef Kehrein, Christoph A Sotriffer
Molecular Dynamics Simulations for Rationalizing Polymer Bioconjugation Strategies: Challenges, Recent Developments, and Future Opportunities. ACS biomaterials science & engineering (2023)
Mathias Diebold, Lars Schönemann, Martin Eilers, Christoph A Sotriffer, Hermann Schindelin
Crystal structure of a covalently linked Aurora-A-MYCN complex. Acta crystallographica. Section D, Structural biology 79 (Pt 1) (2023)
Sebastian Bothe, Petra Hänzelmann, Stephan Böhler, Josef Kehrein, Markus Zehe, Christoph Wiedemann, Ute A Hellmich, Ruth Brenk, Hermann Schindelin, Christoph A Sotriffer
Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97. Communications chemistry 5 (1) (2022)
Sebastian Bothe, Petra Hänzelmann, Stephan Böhler, Josef Kehrein, Markus Zehe, Christoph Wiedemann, Ute A Hellmich, Ruth Brenk, Hermann Schindelin, Christoph A Sotriffer
Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97. Communications chemistry 5 (1) (2022)
Matthias Scheiner, Alexandra Sink, Matthias Hoffmann, Cassandre Vrigneau, Erik Endres, Allison Carles, Christoph A Sotriffer, Tangui Maurice, Michael Decker
Photoswitchable Pseudoirreversible Butyrylcholinesterase Inhibitors Allow Optical Control of Inhibition in Vitro and Enable Restoration of Cognition in an Alzheimer's Disease Mouse Model upon Irradiation. Journal of the American Chemical Society 144 (7) (2022)
Elisabeth Jeanclos, Jan Schlötzer, Kerstin Hadamek, Natalia Yuan-Chen, Mohammad Alwahsh, Robert Hollmann, Stefanie Fratz, Dilan Yesilyurt-Gerhards, Tina Frankenbach, Daria Engelmann, Angelika Keller, Alexandra Kaestner, Werner Schmitz, Martin Neuenschwander, Roland Hergenröder, Christoph A Sotriffer, Jens Peter von Kries, Hermann Schindelin, Antje Gohla
Glycolytic flux control by drugging phosphoglycolate phosphatase. Nature communications 13 (1) (2022)
Niklas Hauptstein, Paria Pouyan, Josef Kehrein, Michael Dirauf, Marc D Driessen, Martina Raschig, Kai Licha, Michael Gottschaldt, Ulrich Sigmar Schubert, Rainer Haag, Lorenz Meinel, Christoph A Sotriffer, Tessa Lühmann
Molecular Insights into Site-Specific Interferon-α2a Bioconjugates Originated from PEG, LPG, and PEtOx. Biomacromolecules 22 (11) (2021)
Darius P Zlotos, Carine M Abdelmalek, Liza S Botros, Maha M Banoub, Yasmine M Mandour, Ulrike Breitinger, Ahmed El Nady, Hans-Georg Breitinger, Christoph A Sotriffer, Carmen Villmann, Anders A Jensen, Gerhard Bringmann
C-2-Linked Dimeric Strychnine Analogues as Bivalent Ligands Targeting Glycine Receptors. Journal of natural products 84 (2) (2021)
Sandra Eltschkner, Josef Kehrein, Thien Anh Le, Shabnam Davoodi, Benjamin Merget, Sneha Basak, Jonas D Weinrich, Johannes Schiebel, Peter J Tonge, Bernd Engels, Christoph A Sotriffer, Caroline Kisker
A Long Residence Time Enoyl-Reductase Inhibitor Explores an Extended Binding Region with Isoenzyme-Dependent Tautomer Adaptation and Differential Substrate-Binding Loop Closure. ACS infectious diseases 7 (4) (2021)
Anja Dölle, Bikash Adhikari, Andreas Krämer, Janik Weckesser, Nicola Berner, Lena Marie Berger, Mathias Diebold, Magdalena M Szewczyk, Dalia Barsyte-Lovejoy, Cheryl H Arrowsmith, Jakob Gebel, Frank Loehr, Volker Dötsch, Martin Eilers, Stephanie Wilhelm, Bernhard Kuster, Christoph A Sotriffer, Elmar Wolf, Stefan Knapp
Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders. Journal of medicinal chemistry 64 (15) (2021)
Johannes Wiest, Josef Kehrein, Marco Saedtler, Klaus Schilling, Eleonora Cataldi, Christoph A Sotriffer, Gerhard Bringmann, Tim Rasmussen, Bettina Boettcher, Mark Cronin-Golomb, Matthias Lehmann, Nathalie Jung, Mike Windbergs, Lorenz Meinel
Controlling Supramolecular Structures of Drugs by Light. Molecular pharmaceutics 17 (12) (2020)
Jean A Boutin, Paula A Witt-Enderby, Christoph A Sotriffer, Darius P Zlotos
Melatonin receptor ligands: A pharmaco-chemical perspective. Journal of pineal research 69 (3) (2020)
Bikash Adhikari, Jelena Bozilovic, Mathias Diebold, Jessica Denise Schwarz, Julia Hofstetter, Martin Schröder, Marek Wanior, Ashwin Narain, Markus Vogt, Nevenka Dudvarski Stankovic, Apoorva Baluapuri, Lars Schönemann, Lorenz Eing, Pranjali Bhandare, Bernhard Kuster, Andreas Schlosser, Stephanie Wilhelm, Christoph A Sotriffer, Stefan Knapp, Elmar Wolf
PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase. Nature chemical biology 16 (11) (2020)
Christian Kersten, Edmond Fleischer, Josef Kehrein, Christoph Borek, Elmar Jaenicke, Christoph A Sotriffer, Ruth Brenk
How To Design Selective Ligands for Highly Conserved Binding Sites: A Case Study Using N-Myristoyltransferases as a Model System. Journal of medicinal chemistry 63 (5) (2019)
Darius P Zlotos, Amal M Y Mohsen, Yasmine M Mandour, Mohamed A Marzouk, Ulrike Breitinger, Carmen Villmann, Hans-Georg Breitinger, Christoph A Sotriffer, Anders A Jensen, Gerhard Bringmann
11-Aminostrychnine and N-(Strychnine-11-yl)propionamide: Synthesis, Configuration, and Pharmacological Evaluation at Glycine Receptors. Journal of natural products 82 (8) (2019)
Yesid A Ramirez, Thomas B Adler, Eva Altmann, Theresa Klemm, Christian Tiesmeyer, Florian Sauer, Stefan G Kathman, Alexander V Statsyuk, Christoph A Sotriffer, Caroline Kisker
Structural Basis of Substrate Recognition and Covalent Inhibition of Cdu1 from Chlamydia trachomatis. ChemMedChem 13 (19) (2018)
Christoph A Sotriffer
Docking of Covalent Ligands: Challenges and Approaches. Molecular informatics 37 (9-10) (2018)
Amal M Y Mohsen, Yasmine M Mandour, Edita Sarukhanyan, Ulrike Breitinger, Carmen Villmann, Maha M Banoub, Hans-Georg Breitinger, Thomas Dandekar, Ulrike Holzgrabe, Christoph A Sotriffer, Anders A Jensen, Darius P Zlotos
Oxime Ethers of (E)-11-Isonitrosostrychnine as Highly Potent Glycine Receptor Antagonists. Journal of natural products 79 (12) (2016)