Stephen C Mack (S C Mack)

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 32

Top Venues

Cell death and differentiation

Nature

Neuro-oncology

Nature cell biology

Baylor College of Medicine

University of Toronto (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Baylor College of Medicine Sep 05 2017

United States

Assistant Professor :: Pediatrics

Cleveland Clinic Lerner Research Institute Jul 22 2014 - Jul 31 2017

United States

Post-Doctoral Research Fellow :: Stem Cell Biology and Regenerative Medicine

Education History

University of Toronto Aug 21 2006 - Jun 09 2014

Canada

PHD :: Laboratory Medicine and Pathobiology

Publications

Daqi Li, Xiefeng Wang, Kexin Chen, Danyang Shan, Gaoyuan Cui, Wei Yuan, Qiankun Lin, Ryan C Gimple, Deobrat Dixit, Chenfei Lu, Danling Gu, Hao You, Jiancheng Gao, Yangqing Li, Tao Kang, Junlei Yang, Hang Yu, Kefan Song, Zhumei Shi, Xiao Fan, Qiulian Wu, Wei Gao, Zhe Zhu, Jianghong Man, Qiang-Hu Wang, Fan Lin, Weiwei Tao, Stephen C Mack, Yun Chen, Junxia Zhang, Chao-Jun Li, Nu Zhang, Yongping You, Xu Qian, Kailin Yang, Jeremy N Rich, Qian Zhang, Xiuxing Wang
IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages. Cell death and differentiation (2024)
Daqi Li, Xiefeng Wang, Kexin Chen, Danyang Shan, Gaoyuan Cui, Wei Yuan, Qiankun Lin, Ryan C Gimple, Deobrat Dixit, Chenfei Lu, Danling Gu, Hao You, Jiancheng Gao, Yangqing Li, Tao Kang, Junlei Yang, Hang Yu, Kefan Song, Zhumei Shi, Xiao Fan, Qiulian Wu, Wei Gao, Zhe Zhu, Jianghong Man, Qiang-Hu Wang, Fan Lin, Weiwei Tao, Stephen C Mack, Yun Chen, Junxia Zhang, Chao-Jun Li, Nu Zhang, Yongping You, Xu Qian, Kailin Yang, Jeremy N Rich, Qian Zhang, Xiuxing Wang
IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages. Cell death and differentiation 31 (6) (2024)
Stephen C Mack, Kelsey C Bertrand
Understanding the mechanisms of diffuse midline glioma cell migration toward therapeutic targeting. Neuro-oncology 26 (3) (2024)
Hsiao-Chi Chen, Peihao He, Malcolm McDonald, Michael R Williamson, Srinidhi Varadharajan, Brittney Lozzi, Junsung Woo, Dong-Joo Choi, Debosmita Sardar, Emmet Huang-Hobbs, Hua Sun, Siri M Ippagunta, Antrix Jain, Ganesh Rao, Thomas E Merchant, David W Ellison, Jeffrey L Noebels, Kelsey C Bertrand, Stephen C Mack, Benjamin Deneen
Histone serotonylation regulates ependymoma tumorigenesis. Nature 632 (8026) (2024)
Daqi Li, Xiefeng Wang, Kexin Chen, Danyang Shan, Gaoyuan Cui, Wei Yuan, Qiankun Lin, Ryan C Gimple, Deobrat Dixit, Chenfei Lu, Danling Gu, Hao You, Jiancheng Gao, Yangqing Li, Tao Kang, Junlei Yang, Hang Yu, Kefan Song, Zhumei Shi, Xiao Fan, Qiulian Wu, Wei Gao, Zhe Zhu, Jianghong Man, Qiang-Hu Wang, Fan Lin, Weiwei Tao, Stephen C Mack, Yun Chen, Junxia Zhang, Chao-Jun Li, Nu Zhang, Yongping You, Xu Qian, Kailin Yang, Jeremy N Rich, Qian Zhang, Xiuxing Wang
IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages. Cell death and differentiation 31 (6) (2024)
Daqi Li, Xiefeng Wang, Kexin Chen, Danyang Shan, Gaoyuan Cui, Wei Yuan, Qiankun Lin, Ryan C Gimple, Deobrat Dixit, Chenfei Lu, Danling Gu, Hao You, Jiancheng Gao, Yangqing Li, Tao Kang, Junlei Yang, Hang Yu, Kefan Song, Zhumei Shi, Xiao Fan, Qiulian Wu, Wei Gao, Zhe Zhu, Jianghong Man, Qiang-Hu Wang, Fan Lin, Weiwei Tao, Stephen C Mack, Yun Chen, Junxia Zhang, Chao-Jun Li, Nu Zhang, Yongping You, Xu Qian, Kailin Yang, Jeremy N Rich, Qian Zhang, Xiuxing Wang
IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages. Cell death and differentiation 31 (6) (2024)
Hsiao-Chi Chen, Peihao He, Malcolm McDonald, Michael R Williamson, Srinidhi Varadharajan, Brittney Lozzi, Junsung Woo, Dong-Joo Choi, Debosmita Sardar, Emmet Huang-Hobbs, Hua Sun, Siri M Ippagunta, Antrix Jain, Ganesh Rao, Thomas E Merchant, David W Ellison, Jeffrey L Noebels, Kelsey C Bertrand, Stephen C Mack, Benjamin Deneen
Histone serotonylation regulates ependymoma tumorigenesis. Nature (2024)
Hsiao-Chi Chen, Peihao He, Malcolm McDonald, Michael R Williamson, Srinidhi Varadharajan, Brittney Lozzi, Junsung Woo, Dong-Joo Choi, Debosmita Sardar, Emmet Huang-Hobbs, Hua Sun, Siri M Ippagunta, Antrix Jain, Ganesh Rao, Thomas E Merchant, David W Ellison, Jeffrey L Noebels, Kelsey C Bertrand, Stephen C Mack, Benjamin Deneen
Histone serotonylation regulates ependymoma tumorigenesis. Nature (2024)
Hsiao-Chi Chen, Peihao He, Malcolm McDonald, Michael R Williamson, Srinidhi Varadharajan, Brittney Lozzi, Junsung Woo, Dong-Joo Choi, Debosmita Sardar, Emmet Huang-Hobbs, Hua Sun, Siri M Ippagunta, Antrix Jain, Ganesh Rao, Thomas E Merchant, David W Ellison, Jeffrey L Noebels, Kelsey C Bertrand, Stephen C Mack, Benjamin Deneen
Histone serotonylation regulates ependymoma tumorigenesis. Nature 632 (8026) (2024)
Stephen C Mack, Kelsey C Bertrand
Understanding the mechanisms of diffuse midline glioma cell migration toward therapeutic targeting. Neuro-oncology 26 (3) (2024)
Stephen C Mack, Kelsey C Bertrand
Understanding the mechanisms of diffuse midline glioma cell migration toward therapeutic targeting. Neuro-oncology 26 (3) (2024)
Daqi Li, Xiefeng Wang, Kexin Chen, Danyang Shan, Gaoyuan Cui, Wei Yuan, Qiankun Lin, Ryan C Gimple, Deobrat Dixit, Chenfei Lu, Danling Gu, Hao You, Jiancheng Gao, Yangqing Li, Tao Kang, Junlei Yang, Hang Yu, Kefan Song, Zhumei Shi, Xiao Fan, Qiulian Wu, Wei Gao, Zhe Zhu, Jianghong Man, Qiang-Hu Wang, Fan Lin, Weiwei Tao, Stephen C Mack, Yun Chen, Junxia Zhang, Chao-Jun Li, Nu Zhang, Yongping You, Xu Qian, Kailin Yang, Jeremy N Rich, Qian Zhang, Xiuxing Wang
IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages. Cell death and differentiation 31 (6) (2024)
Han Zou, Bradley Poore, Emily E Brown, Jieqi Qian, Bin Xie, Evridiki Asimakidou, Vladislav Razskazovskiy, Deanna Ayrapetian, Vaibhav Sharma, Shunjin Xia, Fei Liu, Apeng Chen, Yongchang Guan, Zhengwei Li, Siyi Wanggou, Olivier Saulnier, Michelle Ly, Wendy Fellows-Mayle, Guifa Xi, Tadanori Tomita, Adam C Resnick, Stephen C Mack, Eric H Raabe, Charles G Eberhart, Dandan Sun, Beth E Stronach, Sameer Agnihotri, Gary Kohanbash, Songjian Lu, Karl Herrup, Jeremy N Rich, George K Gittes, Alberto Broniscer, Zhongliang Hu, Xuejun Li, Ian F Pollack, Robert M Friedlander, Sarah J Hainer, Michael D Taylor, Baoli Hu
A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis. Nature cell biology 25 (3) (2023)
Han Zou, Bradley Poore, Emily E Brown, Jieqi Qian, Bin Xie, Evridiki Asimakidou, Vladislav Razskazovskiy, Deanna Ayrapetian, Vaibhav Sharma, Shunjin Xia, Fei Liu, Apeng Chen, Yongchang Guan, Zhengwei Li, Siyi Wanggou, Olivier Saulnier, Michelle Ly, Wendy Fellows-Mayle, Guifa Xi, Tadanori Tomita, Adam C Resnick, Stephen C Mack, Eric H Raabe, Charles G Eberhart, Dandan Sun, Beth E Stronach, Sameer Agnihotri, Gary Kohanbash, Songjian Lu, Karl Herrup, Jeremy N Rich, George K Gittes, Alberto Broniscer, Zhongliang Hu, Xuejun Li, Ian F Pollack, Robert M Friedlander, Sarah J Hainer, Michael D Taylor, Baoli Hu
A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis. Nature cell biology 25 (3) (2023)
Stephen C Mack, Kelsey C Bertrand
A Molecular Blueprint to Targeting ALK Gene Fusions in Glioblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Han Zou, Bradley Poore, Emily E Brown, Jieqi Qian, Bin Xie, Evridiki Asimakidou, Vladislav Razskazovskiy, Deanna Ayrapetian, Vaibhav Sharma, Shunjin Xia, Fei Liu, Apeng Chen, Yongchang Guan, Zhengwei Li, Siyi Wanggou, Olivier Saulnier, Michelle Ly, Wendy Fellows-Mayle, Guifa Xi, Tadanori Tomita, Adam C Resnick, Stephen C Mack, Eric H Raabe, Charles G Eberhart, Dandan Sun, Beth E Stronach, Sameer Agnihotri, Gary Kohanbash, Songjian Lu, Karl Herrup, Jeremy N Rich, George K Gittes, Alberto Broniscer, Zhongliang Hu, Xuejun Li, Ian F Pollack, Robert M Friedlander, Sarah J Hainer, Michael D Taylor, Baoli Hu
A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis. Nature cell biology (2023)
Wei Yuan, Qian Zhang, Danling Gu, Chenfei Lu, Deobrat Dixit, Ryan N Gimple, Yisu Gao, Jiancheng Gao, Daqi Li, Danyan Shan, Lang Hu, Lu Li, Yangqing Li, Shusheng Ci, Hao You, Linping Yan, Kexin Chen, Ningwei Zhao, Chuanhai Xu, Jianyun Lan, Dong Liu, Junxia Zhang, Zhumei Shi, Qiulian Wu, Kailin Yang, Linjie Zhao, Zhixin Qiu, Deguan Lv, Wei Gao, Hui Yang, Fan Lin, Qiang-Hu Wang, Jianghong Man, Chao-Jun Li, Weiwei Tao, Sameer Agnihotri, Xu Qian, Stephen C Mack, Nu Zhang, Yongping You, Jeremy N Rich, Guan Sun, Xiuxing Wang
Dual role of CXCL8 in maintaining the mesenchymal state of glioblastoma stem cells and M2-like tumor-associated macrophages. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Stephen C Mack, Kelsey C Bertrand
A Molecular Blueprint to Targeting ALK Gene Fusions in Glioblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Han Zou, Bradley Poore, Emily E Brown, Jieqi Qian, Bin Xie, Evridiki Asimakidou, Vladislav Razskazovskiy, Deanna Ayrapetian, Vaibhav Sharma, Shunjin Xia, Fei Liu, Apeng Chen, Yongchang Guan, Zhengwei Li, Siyi Wanggou, Olivier Saulnier, Michelle Ly, Wendy Fellows-Mayle, Guifa Xi, Tadanori Tomita, Adam C Resnick, Stephen C Mack, Eric H Raabe, Charles G Eberhart, Dandan Sun, Beth E Stronach, Sameer Agnihotri, Gary Kohanbash, Songjian Lu, Karl Herrup, Jeremy N Rich, George K Gittes, Alberto Broniscer, Zhongliang Hu, Xuejun Li, Ian F Pollack, Robert M Friedlander, Sarah J Hainer, Michael D Taylor, Baoli Hu
A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis. Nature cell biology 25 (3) (2023)
Srinidhi Varadharajan, Stephen C Mack
Leveraging epigenomic patterns to resolve the heterogeneity and origins of CNS germ cell tumors. Neuro-oncology 24 (8) (2022)
Selin Jessa, Abdulshakour Mohammadnia, Ashot S Harutyunyan, Maud Hulswit, Srinidhi Varadharajan, Hussein Lakkis, Nisha Kabir, Zahedeh Bashardanesh, Steven Hébert, Damien Faury, Maria C Vladoiu, Samantha Worme, Marie Coutelier, Brian Krug, Augusto Faria Andrade, Manav Pathania, Andrea Bajic, Alexander G Weil, Benjamin Ellezam, Jeffrey Atkinson, Roy W R Dudley, Jean-Pierre Farmer, Sebastien Perreault, Benjamin A Garcia, Valérie Larouche, Mathieu Blanchette, Livia Garzia, Aparna Bhaduri, Keith L Ligon, Pratiti Bandopadhayay, Michael D Taylor, Stephen C Mack, Nada Jabado, Claudia L Kleinman
K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas. Nature genetics 54 (12) (2022)
Brian J Golbourn, Matthew E Halbert, Katharine Halligan, Srinidhi Varadharajan, Brian Krug, Nneka E Mbah, Nisha Kabir, Ann-Catherine J Stanton, Abigail L Locke, Stephanie M Casillo, Yanhua Zhao, Lauren M Sanders, Allison Cheney, Steven J Mullett, Apeng Chen, Michelle Wassell, Anthony Andren, Jennifer Perez, Esther P Jane, Daniel R David Premkumar, Robert F Koncar, Shideh Mirhadi, Lauren H McCarl, Yue-Fang Chang, Yijen L Wu, Taylor A Gatesman, Andrea F Cruz, Michal Zápotocký, Baoli Hu, Gary Kohanbash, Xiuxing Wang, Alenoush Vartanian, Michael F Moran, Frank Lieberman, Nduka M Amankulor, Stacy G Wendell, Olena M Vaske, Ashok Panigrahy, James Felker, Kelsey C Bertrand, Claudia L Kleinman, Jeremy N Rich, Robert M Friedlander, Alberto Broniscer, Costas Andreas Lyssiotis, Nada Jabado, Ian F Pollack, Stephen C Mack, Sameer Agnihotri
Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome. Nature cancer 3 (5) (2022)
Robert Kupp, Lisa Ruff, Sabrina Terranova, Erica Nathan, Stephane Ballereau, Rory Stark, Chandra Sekhar Reddy Chilamakuri, Nadin Hoffmann, Katherine Wickham-Rahrmann, Marcus Widdess, Amir Arabzade, Yanhua Zhao, Srinidhi Varadharajan, Tuyu Zheng, Mohankumar Murugesan, Stefan M Pfister, Daisuke Kawauchi, Kristian W Pajtler, Benjamin Deneen, Stephen C Mack, Katherine E Masih, Berkley E Gryder, Javed Khan, Richard J Gilbertson
ZFTA Translocations Constitute Ependymoma Chromatin Remodeling and Transcription Factors. Cancer discovery 11 (9) (2021)
Amir Arabzade, Yanhua Zhao, Srinidhi Varadharajan, Hsiao-Chi Chen, Selin Jessa, Bryan Rivas, Austin J Stuckert, Minerva Solis, Alisha Kardian, Dana Tlais, Brian J Golbourn, Ann-Catherine J Stanton, Yuen San Chan, Calla Olson, Kristen L Karlin, Kathleen Kong, Robert Kupp, Baoli Hu, Sarah G Injac, Madeline Ngo, Peter R Wang, Luz A De León, Felix Sahm, Daisuke Kawauchi, Stefan M Pfister, Charles Y Lin, H Courtney Hodges, Irtisha Singh, Thomas F Westbrook, Murali M Chintagumpala, Susan M Blaney, Donald W Parsons, Kristian W Pajtler, Sameer Agnihotri, Richard J Gilbertson, Joanna Yi, Nada Jabado, Claudia L Kleinman, Kelsey C Bertrand, Benjamin Deneen, Stephen C Mack
ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma. Cancer discovery 11 (9) (2021)
Tuyu Zheng, David R Ghasemi, Konstantin Okonechnikov, Andrey Korshunov, Martin Sill, Kendra K Maass, Patricia Benites Goncalves da Silva, Marina Ryzhova, Johannes Gojo, Damian Stichel, Amir Arabzade, Robert Kupp, Julia Benzel, Shinichiro Taya, Toma Adachi, Ryo Shiraishi, Nicolas U Gerber, Dominik Sturm, Jonas Ecker, Philipp Sievers, Florian Selt, Rebecca Chapman, Christine Haberler, Dominique Figarella-Branger, Guido Reifenberger, Gudrun Fleischhack, Stefan Rutkowski, Andrew M Donson, Vijay Ramaswamy, David Capper, David W Ellison, Christel C Herold-Mende, Ulrich Schüller, Sebastian Brandner, Pablo Hernáiz Driever, Johan M Kros, Matija Snuderl, Till Milde, Richard G Grundy, Mikio Hoshino, Stephen C Mack, Richard J Gilbertson, David T W Jones, Marcel Kool, Andreas von Deimling, Stefan M Pfister, Felix Sahm, Daisuke Kawauchi, Kristian W Pajtler
Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion-Positive Supratentorial Ependymomas. Cancer discovery 11 (9) (2021)
Xiuxing Wang, Kailin Yang, Qiulian Wu, Leo J Y Kim, Andrew R Morton, Ryan N Gimple, Briana C Prager, Yu Shi, Wenchao Zhou, Shruti Bhargava, Zhe Zhu, Li Jiang, Weiwei Tao, Zhixin Qiu, Linjie Zhao, Guoxing Zhang, Xiqing Li, Sameer Agnihotri, Paul S Mischel, Stephen C Mack, Shideng Bao, Jeremy N Rich
Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells. Science translational medicine 11 (504) (2020)
Briana C Prager, Harish N Vasudevan, Deobrat Dixit, Jean A Bernatchez, Qiulian Wu, Lisa C Wallace, Shruti Bhargava, Derrick Lee, Bradley H King, Andrew R Morton, Ryan N Gimple, Melike Pekmezci, Zhe Zhu, Jair L Siqueira-Neto, Xiuxing Wang, Qi Xie, Clark Chen, Gene H Barnett, Michael A Vogelbaum, Stephen C Mack, Lukas Chavez, Arie Perry, David R Raleigh, Jeremy N Rich
The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies. Cancer discovery 10 (11) (2020)
A Stuckert, K C Bertrand, P Wang, A Smith, Stephen C Mack
Weighing ependymoma as an epigenetic disease. Journal of neuro-oncology 150 (1) (2020)
A Arabzade, A J Stuckert, K C Bertrand, Stephen C Mack
Invited Review: The role and contribution of transcriptional enhancers in brain cancer. Neuropathology and applied neurobiology 46 (1) (2020)
Kelsey C Bertrand, Claudia C Faria, Patryk Skowron, Amanda Luck, Livia Garzia, Xiaochong Wu, Sameer Agnihotri, Christian A Smith, Michael D Taylor, Stephen C Mack, James T Rutka
A functional genomics approach to identify pathways of drug resistance in medulloblastoma. Acta neuropathologica communications 6 (1) (2018)
Xun Jin, Leo J Y Kim, Qiulian Wu, Lisa C Wallace, Briana C Prager, Tanwarat Sanvoranart, Ryan C Gimple, Xiuxing Wang, Stephen C Mack, Tyler E Miller, Ping Huang, Claudia L Valentim, Qi-Gang Zhou, Jill S Barnholtz-Sloan, Shideng Bao, Andrew E Sloan, Jeremy N Rich
Targeting glioma stem cells through combined BMI1 and EZH2 inhibition. Nature medicine 23 (11) (2017)
Stephen C Mack, Christopher G Hubert, Tyler E Miller, Michael D Taylor, Jeremy N Rich
An epigenetic gateway to brain tumor cell identity. Nature neuroscience 19 (1) (2016)

Stephen C Mack.css-eqlu8i{font-size:small;padding-left:4px;} (S C Mack)

Publication Activity (10 Years)

Top Topics

Top Venues

Stephen C Mack (S C Mack)