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Sakthivel Sadayappan

Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 33

Top Venues

The Journal of general physiology

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

International journal of molecular sciences

University of Cincinnati

Madurai Kamaraj University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Cincinnati Aug 15o 2016

United States

Professor :: Internal Medicine

Education History

Madurai Kamaraj University

India

PHD :: Biochemistry

Publications

Mohit Kumar, Kobra Haghighi, Sheryl Koch, Jack Rubinstein, Francesca Stillitano, Roger J Hajjar, Evangelia G Kranias, Sakthivel Sadayappan
Myofilament Alterations Associated with Human R14del-Phospholamban Cardiomyopathy. International journal of molecular sciences 24 (3) (2023)
Shane Nelson, Samantha Beck-Previs, Sakthivel Sadayappan, Carl Tong, David M Warshaw
Myosin-binding protein C stabilizes, but is not the sole determinant of SRX myosin in cardiac muscle. The Journal of general physiology 155 (4) (2023)
Shane Nelson, Samantha Beck-Previs, Sakthivel Sadayappan, Carl Tong, David M Warshaw
Myosin-binding protein C stabilizes, but is not the sole determinant of SRX myosin in cardiac muscle. The Journal of general physiology 155 (4) (2023)
Maicon Landim-Vieira, Weikang Ma, Taejeong Song, Hosna Rastegarpouyani, Henry Gong, Isabella Leite Coscarella, Sylvia J P Bogaards, Stefan P Conijn, Coen A C Ottenheijm, Hyun S Hwang, Maria Papadaki, Björn C Knollmann, Sakthivel Sadayappan, Thomas C Irving, Vitold E Galkin, Prescott Bryant Chase, Jose Renato Pinto
Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function. Proceedings of the National Academy of Sciences of the United States of America 120 (23) (2023)
Shane Nelson, Samantha Beck-Previs, Sakthivel Sadayappan, Carl Tong, David M Warshaw
Myosin-binding protein C stabilizes, but is not the sole determinant of SRX myosin in cardiac muscle. The Journal of general physiology 155 (4) (2023)
Mohit Kumar, Kobra Haghighi, Sheryl Koch, Jack Rubinstein, Francesca Stillitano, Roger J Hajjar, Evangelia G Kranias, Sakthivel Sadayappan
Myofilament Alterations Associated with Human R14del-Phospholamban Cardiomyopathy. International journal of molecular sciences 24 (3) (2023)
Shane Nelson, Samantha Beck-Previs, Sakthivel Sadayappan, Carl Tong, David M Warshaw
Myosin-binding protein C stabilizes, but is not the sole determinant of SRX myosin in cardiac muscle. The Journal of general physiology 155 (4) (2023)
Weikang Ma, Vivek P Jani, Taejeong Song, Chengqian Gao, Henry Gong, Sakthivel Sadayappan, David A Kass, Thomas C Irving
The structural OFF and ON states of myosin can be decoupled from the biochemical super-relaxed and disordered-relaxed states. bioRxiv : the preprint server for biology (2023)
Hongyan Zhao, Peng Wang, Xiaohong Wang, Wa Du, Hui-Hui Yang, Yueying Liu, Shu-Nan Cui, Wei Huang, Tianqing Peng, Jing Chen, Chen Gao, Yigang Wang, Sakthivel Sadayappan, Chengen Ma, Yanbo Fan, Chunting Wang, Guo-Chang Fan
Lipocalin 10 is essential for protection against inflammation-triggered vascular leakage by activating LRP2-Ssh1 signaling pathway. Cardiovascular research (2023)
Shane Nelson, Samantha Beck-Previs, Sakthivel Sadayappan, Carl Tong, David M Warshaw
Myosin-binding protein C stabilizes, but is not the sole determinant of SRX myosin in cardiac muscle. The Journal of general physiology 155 (4) (2023)
Mohit Kumar, Kobra Haghighi, Sheryl Koch, Jack Rubinstein, Francesca Stillitano, Roger J Hajjar, Evangelia G Kranias, Sakthivel Sadayappan
Myofilament Alterations Associated with Human R14del-Phospholamban Cardiomyopathy. International journal of molecular sciences 24 (3) (2023)
Anthony L Hessel, Michel Kuehn, Seong-Won Han, Weikang Ma, Thomas C Irving, Brent A Momb, Taejeong Song, Sakthivel Sadayappan, Wolfgang A Linke, Bradley M Palmer
Fast myosin binding protein C knockout in skeletal muscle alters length-dependent activation and myofilament structure. bioRxiv : the preprint server for biology (2023)
Jamila H Siamwala, Francesco S Pagano, Patrycja M Dubielecka, Malina J Ivey, Jose Pedro Guirao-Abad, Alexander Zhao, Sonja Chen, Haley Granston, Jae Yun Jeong, Sharon Rounds, Onur Kanisicak, Sakthivel Sadayappan, Richard J Gilbert
IL-1β-mediated adaptive reprogramming of endogenous human cardiac fibroblasts to cells with immune features during fibrotic remodeling. Communications biology 6 (1) (2023)
Marisa J Stachowski-Doll, Maria Papadaki, Thomas G Martin, Weikang Ma, Henry M Gong, Stephanie Shao, Shi Shen, Nitha Aima Muntu, Mohit Kumar, Edith Perez, Jody L Martin, Christine S Moravec, Sakthivel Sadayappan, Lorenzo R Sewanan, Thomas Irving, Jonathan A Kirk
GSK-3β Localizes to the Cardiac Z-Disc to Maintain Length Dependent Activation. Circulation research 130 (6) (2022)
Yuliang Feng, Liuyang Cai, Wanzi Hong, Chunxiang Zhang, Ning Tan, Mingyang Wang, Cheng Wang, Feng Liu, Xiaohong Wang, Jianyong Ma, Chen Gao, Mohit Kumar, Yuanxi Mo, Qingshan Geng, Changjun Luo, Yan Lin, Haiyang Chen, Shuang-Yin Wang, Michael J Watson, Anil G Jegga, Roger A Pedersen, Ji-Dong Fu, Zhao V Wang, Guo-Chang Fan, Sakthivel Sadayappan, Yigang Wang, Siim Pauklin, Feng Huang, Wei Huang, Lei Jiang
Rewiring of 3D Chromatin Topology Orchestrates Transcriptional Reprogramming and the Development of Human Dilated Cardiomyopathy. Circulation 145 (22) (2022)
Jared M McLendon, Xiaoming Zhang, Daniel S Matasic, Mohit Kumar, Olha M Koval, Isabella M Grumbach, Sakthivel Sadayappan, Barry London, Ryan L Boudreau
Knockout of Sorbin And SH3 Domain Containing 2 (Sorbs2) in Cardiomyocytes Leads to Dilated Cardiomyopathy in Mice. Journal of the American Heart Association 11 (13) (2022)
Justin G Boyer, Jiuzhou Huo, Sarah Han, Julian R Havens, Vikram Prasad, Brian Leei Lin, David A Kass, Taejeong Song, Sakthivel Sadayappan, Ramzi J Khairallah, Christopher W Ward, Jeffery D Molkentin
Depletion of skeletal muscle satellite cells attenuates pathology in muscular dystrophy. Nature communications 13 (1) (2022)
Sakthivel Sadayappan, Evangelia G Kranias
In Memoriam Tribute to Jeffrey Robbins, PhD (1950-2022). Circulation research 131 (11) (2022)
Kobra Haghighi, George Gardner, Elizabeth Vafiadaki, Mohit Kumar, Lisa C Green, Jianyong Ma, Jeffrey S Crocker, Sheryl Koch, Demetrios A Arvanitis, Phillip Bidwell, Jack Rubinstein, Rutger van de Leur, Pieter A M Doevendans, Fadi G Akar, Michael Tranter, Hong-Sheng Wang, Sakthivel Sadayappan, Deeptankar DeMazumder, Despina Sanoudou, Roger J Hajjar, Francesca Stillitano, Evangelia G Kranias
Impaired Right Ventricular Calcium Cycling Is an Early Risk Factor in R14del-Phospholamban Arrhythmias. Journal of personalized medicine 11 (6) (2021)
Athiththan Yogeswaran, Christian Troidl, James W McNamara, Jochen Wilhelm, Theresa Truschel, Laila Widmann, Muhammad Aslam, Christian W Hamm, Sakthivel Sadayappan, Christoph Lipps
The C0-C1f Region of Cardiac Myosin Binding Protein-C Induces Pro-Inflammatory Responses in Fibroblasts via TLR4 Signaling. Cells 10 (6) (2021)
Sholeh Bazrafshan, Hani Kushlaf, Mashhood Kakroo, John Quinlan, Richard C Becker, Sakthivel Sadayappan
Genetic Modifiers of Hereditary Neuromuscular Disorders and Cardiomyopathy. Cells 10 (2) (2021)
Mohammed Arif, Perwez Alam, Rafeeq Ph Ahmed, Raghav Pandey, Hafeez M Faridi, Sakthivel Sadayappan
Upregulated Angiogenesis Is Incompetent to Rescue Dilated Cardiomyopathy Phenotype in Mice. Cells 10 (4) (2021)
Taejeong Song, James W McNamara, Weikang Ma, Maicon Landim-Vieira, Kyoung Hwan Lee, Lisa A Martin, Judith A Heiny, John N Lorenz, Roger Craig, Jose Renato Pinto, Thomas C Irving, Sakthivel Sadayappan
Fast skeletal myosin-binding protein-C regulates fast skeletal muscle contraction. Proceedings of the National Academy of Sciences of the United States of America 118 (17) (2021)
Alyssa A W Cramer, Vikram Prasad, Einar Eftestøl, Taejeong Song, Kenth-Arne Hansson, Hannah F Dugdale, Sakthivel Sadayappan, Julien Ochala, Kristian Gundersen, Douglas P Millay
Nuclear numbers in syncytial muscle fibers promote size but limit the development of larger myonuclear domains. Nature communications 11 (1) (2020)
Mohit Kumar, Kobra Haghighi, Evangelia G Kranias, Sakthivel Sadayappan
Phosphorylation of cardiac myosin-binding protein-C contributes to calcium homeostasis. The Journal of biological chemistry 295 (32) (2020)
Mohit Kumar, Chellappagounder Thangavel, Richard C Becker, Sakthivel Sadayappan
Monoclonal Antibody-Based Immunotherapy and Its Role in the Development of Cardiac Toxicity. Cancers 13 (1) (2020)
James W McNamara, Rohit R Singh, Sakthivel Sadayappan
Cardiac myosin binding protein-C phosphorylation regulates the super-relaxed state of myosin. Proceedings of the National Academy of Sciences of the United States of America 116 (24) (2019)
Taejeong Song, Palanikumar Manoharan, Douglas P Millay, Sheryl E Koch, Jack Rubinstein, Judith A Heiny, Sakthivel Sadayappan
Dilated cardiomyopathy-mediated heart failure induces a unique skeletal muscle myopathy with inflammation. Skeletal muscle 9 (1) (2019)
Amy Li, Shane R Nelson, Sheema Rahmanseresht, Filip Braet, Anabelle S Cornachione, Samantha Beck Previs, Thomas S O'Leary, James W McNamara, Dilson E Rassier, Sakthivel Sadayappan, Michael J Previs, David M Warshaw
Skeletal MyBP-C isoforms tune the molecular contractility of divergent skeletal muscle systems. Proceedings of the National Academy of Sciences of the United States of America 116 (43) (2019)
Sakthivel Sadayappan, Richard J Gilbert
The potential role of neddylation in pre- and postnatal cardiac remodeling. American journal of physiology. Heart and circulatory physiology 317 (2) (2019)
Brian Leei Lin, Amy Li, Ji Young Mun, Michael J Previs, Samantha Beck Previs, Stuart G Campbell, Cristobal G Dos Remedios, Pieter de P Tombe, Roger Craig, David M Warshaw, Sakthivel Sadayappan
Skeletal myosin binding protein-C isoforms regulate thin filament activity in a Ca2+-dependent manner. Scientific reports 8 (1) (2018)
Wei Huang, Yuliang Feng, Jialiang Liang, Hao Yu, Cheng Wang, Boyu Wang, Mingyang Wang, Lin Jiang, Wei Meng, Wenfeng Cai, Mario Medvedovic, Jenny Chen, Christian Paul, W Sean Davidson, Sakthivel Sadayappan, Peter J Stambrook, Xi-Yong Yu, Yigang Wang
Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration. Nature communications 9 (1) (2018)
Shiv Kumar Viswanathan, Heather K Sanders, James W McNamara, Aravindakshan Jagadeesan, Arshad Jahangir, A Jamil Tajik, Sakthivel Sadayappan
Hypertrophic cardiomyopathy clinical phenotype is independent of gene mutation and mutation dosage. PloS one 12 (11) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Sakthivel Sadayappan