Severin Lechner

Publication Activity (10 Years)

Years Active: 2022-2024
Publications (10 Years): 6

Top Topics

Liquid Chromatography

Induced Apoptosis

Top Venues

Nature chemical biology

Nature biotechnology

The EMBO journal

Science (New York, N.Y.)

This page only lists publications with an associated author ORCID identifier.

Publications

Stephan Eckert, Nicola Berner, Karl Kramer, Annika Schneider, Julian Müller, Severin Lechner, Sarah Brajkovic, Amirhossein Sakhteman, Christian Graetz, Jonas Fackler, Michael Dudek, Michael W Pfaffl, Percy Knolle, Stephanie Wilhelm, Bernhard Kuster
Decrypting the molecular basis of cellular drug phenotypes by dose-resolved expression proteomics. Nature biotechnology (2024)
Johanna Tüshaus, Amirhossein Sakhteman, Severin Lechner, Matthew The, Eike Mucha, Christoph Krisp, Jürgen Schlegel, Claire Delbridge, Bernhard Kuster
A region-resolved proteomic map of the human brain enabled by high-throughput proteomics. The EMBO journal (2023)
Severin Lechner, Raphael R Steimbach, Longlong Wang, Marshall L Deline, Yun-Chien Chang, Tobias Fromme, Martin Klingenspor, Patrick Matthias, Aubry K Miller, Guillaume Médard, Bernhard Kuster
Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid. Nature communications 14 (1) (2023)
Jana Zecha, Florian P Bayer, Svenja Wiechmann, Julia Woortman, Nicola Berner, Julian Müller, Annika Schneider, Karl Kramer, Mar Abril-Gil, Thomas A Hopf, Leonie Reichart, Lin Chen, Fynn M Hansen, Severin Lechner, Patroklos Samaras, Stephan Eckert, Ludwig Lautenbacher, Maria Reinecke, Firas Hamood, Polina Prokofeva, Larsen Vornholz, Chiara Falcomatà, Madeleine Dorsch, Ayla Schröder, Anton Venhuizen, Stephanie Wilhelm, Guillaume Médard, Gabriele Stoehr, Juergen Ruland, Barbara M Grüner, Dieter Saur, Maike Buchner, Benjamin Ruprecht, Hannes Hahne, Matthew The, Mathias Wilhelm, Bernhard Kuster
Decrypting drug actions and protein modifications by dose- and time-resolved proteomics. Science (New York, N.Y.) (2023)
Raphael R Steimbach, Corey J Herbst-Gervasoni, Severin Lechner, Tracy Murray Stewart, Glynis Klinke, Johannes Ridinger, Magalie N E Géraldy, Gergely Tihanyi, Jackson R Foley, Ulrike Uhrig, Bernhard Kuster, Gernot Poschet, Robert A Casero, Guillaume Médard, Ina Oehme, David W Christianson, Nikolas Gunkel, Aubry K Miller
Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout. Journal of the American Chemical Society 144 (41) (2022)
Severin Lechner, Martin Ian P Malgapo, Christian Graetz, Raphael R Steimbach, Agnes Baron, Patrick Leopold Rüther, Simon Nadal, Carmen Stumpf, Christina Loos, Xin Ku, Polina Prokofeva, Ludwig Lautenbacher, Tino Heimburg, Vivian Würf, Chen Meng, Mathias Wilhelm, Wolfgang Sippl, Karin Kleigrewe, Josch K Pauling, Karl Kramer, Aubry K Miller, Michael W Pfaffl, Maurine E Linder, Bernhard Kuster, Guillaume Médard
Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target. Nature chemical biology 18 (8) (2022)