Stefani Spranger

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 14

Top Topics

Dendritic Cells

Immune Response

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Science immunology

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Duncan M Morgan, Brendan L Horton, Vidit Bhandarkar, Richard Van, Teresa Dinter, Maria Zagorulya, John Christopher Love, Stefani Spranger
Expansion of tumor-reactive CD8 + T cell clonotypes occurs in the spleen in response to immune checkpoint blockade. Science immunology 9 (99) (2024)
Dig B Mahat, Heena Kumra, Sarah A Castro, Emily Metcalf, Kim Nguyen, Ryo Morisue, William W Ho, Ivy Chen, Brandon Sullivan, Leon K Yim, Arundeep Singh, Jiayu Fu, Sean K Waterton, Yu-Chi Cheng, Sylvie Roberge, Enrico Moiso, Vikash P Chauhan, Hernandez Moura Silva, Stefani Spranger, Rakesh K Jain, Phillip A Sharp
Mutant p53 Exploits Enhancers to Elevate Immunosuppressive Chemokine Expression and Impair Immune Checkpoint Inhibitors in Pancreatic Cancer. bioRxiv : the preprint server for biology (2024)
Sachin H Bhagchandani, Farrukh Vohidov, Lauren E Milling, Evelyn Yuzhou Tong, Christopher M Brown, Michelle L Ramseier, Bin Liu, Timothy B Fessenden, Hung V-T Nguyen, Gavin R Kiel, Lori Won, Robert S Langer, Stefani Spranger, Alex K Shalek, Darrell J Irvine, Jeremiah A Johnson
Engineering kinetics of TLR7/8 agonist release from bottlebrush prodrugs enables tumor-focused immune stimulation. Science advances 9 (16) (2023)
Kim Bich Nguyen, Malte Roerden, Christopher J Copeland, Coralie M Backlund, Nory G Klop-Packel, Tanaka Remba, Byungji Kim, Nishant K Singh, Michael E Birnbaum, Darrell J Irvine, Stefani Spranger
Decoupled neoantigen cross-presentation by dendritic cells limits anti-tumor immunity against tumors with heterogeneous neoantigen expression. eLife 12 (2023)
Brianna M Lax, Joseph R Palmeri, Emi A Lutz, Allison Sheen, Jordan A Stinson, Lauren Duhamel, Luciano Santollani, Alan Kennedy, Adrienne M Rothschilds, Stefani Spranger, David Michael Sansom, Karl Dane Wittrup
Both intratumoral regulatory T cell depletion and CTLA-4 antagonism are required for maximum efficacy of anti-CTLA-4 antibodies. Proceedings of the National Academy of Sciences of the United States of America 120 (31) (2023)
Alex M Jaeger, Lauren E Stopfer, Ryuhjin Ahn, Emma A Sanders, Demi A Sandel, William A Freed-Pastor, William M Rideout, Santiago Naranjo, Tim Fessenden, Kim B Nguyen, Peter S Winter, Ryan E Kohn, Peter M K Westcott, Jason M Schenkel, Sean-Luc Shanahan, Alex K Shalek, Stefani Spranger, Forest M White, Tyler Jacks
Deciphering the immunopeptidome in vivo reveals new tumour antigens. Nature 607 (7917) (2022)
Satyaki Sengupta, Sanjukta Das, Angela C Crespo, Annelisa M Cornel, Anand G Patel, Navin R Mahadevan, Marco Campisi, Alaa K Ali, Bandana Sharma, Jared H Rowe, Hao Huang, David N Debruyne, Esther D Cerda, Malgorzata Krajewska, Ruben Dries, Minyue Chen, Shupei Zhang, Luigi Soriano, Malkiel A Cohen, Rogier Versteeg, Rudolf Jaenisch, Stefani Spranger, Rizwan Romee, Brian C Miller, David A Barbie, Stefan Nierkens, Michael A Dyer, Judy Lieberman, Rani E George
Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes. Nature cancer 3 (10) (2022)
Tim B Fessenden, Lauren E Stopfer, Fiona Chatterjee, Julian Zulueta, Josh Mesfin, Therese Cordero Dumit, Irene Reijers, Esmée P Hoefsmit, Christian Blank, Forest White, Stefani Spranger
Dendritic cell-mediated cross presentation of tumor-derived peptides is biased against plasma membrane proteins. Journal for immunotherapy of cancer 10 (7) (2022)
Emi A Lutz, Yash Agarwal, Noor Momin, Sarah C Cowles, Joseph R Palmeri, Ellen Duong, Vladlena Hornet, Allison Sheen, Brianna M Lax, Adrienne M Rothschilds, Darrell J Irvine, Stefani Spranger, Karl Dane Wittrup
Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies. Proceedings of the National Academy of Sciences of the United States of America 119 (36) (2022)
Brendan L Horton, Duncan M Morgan, Noor Momin, Maria Zagorulya, Elen Torres-Mejia, Vidit Bhandarkar, Karl Dane Wittrup, John Christopher Love, Stefani Spranger
Lack of CD8+ T cell effector differentiation during priming mediates checkpoint blockade resistance in non-small cell lung cancer. Science immunology 6 (64) (2021)
Brendan L Horton, Stefani Spranger
CD36 - the Achilles' heel of Treg cells. Nature immunology 21 (3) (2020)
Noor Momin, Naveen K Mehta, Nitasha R Bennett, Leyuan Ma, Joseph R Palmeri, Magnolia M Chinn, Emi A Lutz, Byong Ha Kang, Darrell J Irvine, Stefani Spranger, Karl Dane Wittrup
Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy. Science translational medicine 11 (498) (2020)
Stefani Spranger, Jason J Luke, Riyue Bao, Yuanyuan Zha, Kyle M Hernandez, Yan Li, Alexander P Gajewski, Jorge Andrade, Thomas F Gajewski
Density of immunogenic antigens does not explain the presence or absence of the T-cell-inflamed tumor microenvironment in melanoma. Proceedings of the National Academy of Sciences of the United States of America 113 (48) (2016)
César Evaristo, Stefani Spranger, Sarah E Barnes, Michelle L Miller, Luciana L Molinero, Frederick L Locke, Thomas F Gajewski, Maria-Luisa Alegre
Cutting Edge: Engineering Active IKKβ in T Cells Drives Tumor Rejection. Journal of immunology (Baltimore, Md. : 1950) 196 (7) (2016)