Alex K Shalek (Alex Shalek)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 76

Top Venues

bioRxiv : the preprint server for biology

Nature communications

Microbiology spectrum

Science translational medicine

Massachusetts Institute of Technology

Harvard University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Massachusetts Institute of Technology Jul 01 2019

United States

Associate Professor :: Chemistry

Broad Institute Jul 01 2019

United States

Institute Member

Massachusetts Institute of Technology Jan 01 2018

United States

Extramural Member :: Koch Institute for Integrative Cancer Research

Massachusetts Institute of Technology

United States

Core Member :: Institute for Medical Engineering and Science

Ragon Institute

United States

Associate Member

Harvard-MIT Division of Health Sciences and Technology

United States

Instructor :: HST

Massachusetts General Hospital

United States

Assistant :: Immunology

Massachusetts Institute of Technology - Jun 30 2019

United States

Assistant Professor :: Chemistry

Broad Institute - Jun 30 2019

United States

Associate Member :: Cell Circuits

Broad Institute

United States

Postdoctoral Fellow - Regev Lab :: Cell Circuits

Harvard University

United States

Postdoctoral Fellow - Park Lab :: Chemistry and Chemical Biology

Education History

Harvard University

United States

PHD :: Chemistry and Chemical Biology

Publications

Julien Dilly, Megan T Hoffman, Laleh Abbassi, Ziyue Li, Francesca Paradiso, Brendan D Parent, Connor J Hennessey, Alexander C Jordan, Micaela Morgado, Shatavisha Dasgupta, Giselle A Uribe, Annan Yang, Kevin S Kapner, Felix P Hambitzer, Li Qiang, Hanrong Feng, Jacob Geisberg, Junning Wang, Kyle E Evans, Hengyu Lu, Aislyn Schalck, Ningping Feng, Anastasia M Lopez, Christopher A Bristow, Michael P Kim, Kimal I Rajapakshe, Vahid Bahrambeigi, Jennifer A Roth, Kavita Garg, Paola A Guerrero, Ben Z Stanger, Simona Cristea, Scott W Lowe, Timour Baslan, Eliezer Van Allen, Joseph D Mancias, Emily Chan, Abraham Anderson, Yuliya V Katlinskaya, Alex K Shalek, David S Hong, Shubham Pant, Jill Hallin, Kenna Anderes, Peter Olson, Timothy P Heffernan, Seema Chugh, James G Christensen, Anirban Maitra, Brian M Wolpin, Srivatsan Raghavan, Jonathan Andrew Nowak, Peter S Winter, Stephanie K Dougan, Andrew J Aguirre
Mechanisms of resistance to oncogenic KRAS inhibition in pancreatic cancer. Cancer discovery (2024)
Carly G K Ziegler, Anna H Owings, Michelle Galeas-Pena, Samuel W Kazer, Vincent N Miao, Andrew W Navia, Ying Tang, Joshua D Bromley, Peter Lotfy, Meredith Sloan, Hannah Laird, Haley B Williams, Micayla George, Riley S Drake, Yilianys Pride, George E Abraham, Michal Senitko, Tanya O Robinson, Gill Diamond, Michail S Lionakis, Alex K Shalek, José Ordovas-Montañes, Bruce H Horwitz, Sarah Camille Glover
An enhanced IL17 and muted type I interferon nasal epithelial cell state characterizes severe COVID-19 with fungal coinfection. Microbiology spectrum 12 (6) (2024)
Joachim De Jonghe, James W Opzoomer, Amaia Vilas-Zornoza, Peter Crane, Benedikt S Nilges, Marco Vicari, Hower Lee, David Lara-Astiaso, Torsten Gross, Jörg Morf, Kim Schneider, Juliana Cudini, Lorenzo Ramos-Mucci, Dylan Mooijman, Katarína Tiklová, Sergio Marco Salas, Christoffer Mattsson Langseth, Nachiket D Kashikar, Charles E S Roberts, null null, Joakim Lundeberg, Mats Nilsson, Alex K Shalek, Adam P Cribbs, Jake P Taylor-King
A community effort to track commercial single-cell and spatial 'omic technologies and business trends. Nature biotechnology 42 (7) (2024)
Carly G K Ziegler, Anna H Owings, Michelle Galeas-Pena, Samuel W Kazer, Vincent N Miao, Andrew W Navia, Ying Tang, Joshua D Bromley, Peter Lotfy, Meredith Sloan, Hannah Laird, Haley B Williams, Micayla George, Riley S Drake, Yilianys Pride, George E Abraham, Michal Senitko, Tanya O Robinson, Gill Diamond, Michail S Lionakis, Alex K Shalek, José Ordovas-Montañes, Bruce H Horwitz, Sarah Camille Glover
An enhanced IL17 and muted type I interferon nasal epithelial cell state characterizes severe COVID-19 with fungal coinfection. Microbiology spectrum 12 (6) (2024)
Robert Krause, Paul Ogongo, Liku Tezera, Mohammed Ahmed, Ian Mbano, Mark Chambers, Abigail Ngoepe, Magalli Magnoumba, Daniel Muema, Farina Karim, Khadija Khan, Kapongo Lumamba, Kievershen Nargan, Rajhmun Madansein, Adrie J C Steyn, Alex K Shalek, Paul Elkington, Alasdair Leslie
B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles. Communications biology 7 (1) (2024)
Chibuikem Nwizu, Madeline Hughes, Michelle L Ramseier, Andrew W Navia, Alex K Shalek, Nicolo Fusi, Srivatsan Raghavan, Peter S Winter, Ava P Soleimany, Lorin Crawford
Scalable nonparametric clustering with unified marker gene selection for single-cell RNA-seq data. bioRxiv : the preprint server for biology (2024)
Valerie Lensch, Adele Gabba, Robert Hincapie, Sachin H Bhagchandani, Ankit Basak, Mohammad Murshid Alam, Darrell J Irvine, Alex K Shalek, Jeremiah A Johnson, Neal K Devaraj, Laura L Kiessling
Glycan-costumed virus-like particles promote type 1 anti-tumor immunity. bioRxiv : the preprint server for biology (2024)
Valerie Lensch, Adele Gabba, Robert Hincapie, Sachin H Bhagchandani, Ankit Basak, Mohammad Murshid Alam, Darrell J Irvine, Alex K Shalek, Jeremiah A Johnson, Neal K Devaraj, Laura L Kiessling
Glycan-costumed virus-like particles promote type 1 anti-tumor immunity. bioRxiv : the preprint server for biology (2024)
James Kaminski, Ryan A Fleming, Francesca Alvarez Calderon, Marlana B Winschel, Connor McGuckin, Emily E Ho, Fay Eng, Xianliang Rui, Paula Keskula, Lorenzo Cagnin, Joanne Charles, Jillian Zavistaski, Steven P Margossian, Malika A Kapadia, James B Rottman, Jennifer Lane, Susanne H C Baumeister, Victor Tkachev, Alex K Shalek, Leslie S Kean, Ulrike Gerdemann
B-cell-directed CAR T-cell therapy activates CD8+ cytotoxic CARneg bystander T cells in patients and nonhuman primates. Blood 144 (1) (2024)
Carly G K Ziegler, Anna H Owings, Michelle Galeas-Pena, Samuel W Kazer, Vincent N Miao, Andrew W Navia, Ying Tang, Joshua D Bromley, Peter Lotfy, Meredith Sloan, Hannah Laird, Haley B Williams, Micayla George, Riley S Drake, Yilianys Pride, George E Abraham, Michal Senitko, Tanya O Robinson, Gill Diamond, Michail S Lionakis, Alex K Shalek, José Ordovas-Montañes, Bruce H Horwitz, Sarah Camille Glover
An enhanced IL17 and muted type I interferon nasal epithelial cell state characterizes severe COVID-19 with fungal coinfection. Microbiology spectrum 12 (6) (2024)
Valerie Lensch, Adele Gabba, Robert Hincapie, Sachin H Bhagchandani, Ankit Basak, Mohammad Murshid Alam, Darrell J Irvine, Alex K Shalek, Jeremiah A Johnson, Neal K Devaraj, Laura L Kiessling
Glycan-costumed virus-like particles promote type 1 anti-tumor immunity. bioRxiv : the preprint server for biology (2024)
Carly G K Ziegler, Anna H Owings, Michelle Galeas-Pena, Samuel W Kazer, Vincent N Miao, Andrew W Navia, Ying Tang, Joshua D Bromley, Peter Lotfy, Meredith Sloan, Hannah Laird, Haley B Williams, Micayla George, Riley S Drake, Yilianys Pride, George E Abraham, Michal Senitko, Tanya O Robinson, Gill Diamond, Michail S Lionakis, Alex K Shalek, José Ordovas-Montañes, Bruce H Horwitz, Sarah Camille Glover
An enhanced IL17 and muted type I interferon nasal epithelial cell state characterizes severe COVID-19 with fungal coinfection. Microbiology spectrum 12 (6) (2024)
Sharanya Sivanand, Yetis Gultekin, Peter S Winter, Sidney Y Vermeulen, Konstantine M Tchourine, Keene L Abbott, Laura V Danai, Florian Gourgue, Brian T Do, Kayla Crowder, Tenzin Kunchok, Allison N Lau, Alicia M Darnell, Alexandria Jefferson, Satoru Morita, Dan G Duda, Andrew J Aguirre, Brian M Wolpin, Nicole Henning, Virginia Spanoudaki, Laura Maiorino, Darrell J Irvine, Ömer H Yilmaz, Caroline A Lewis, Dennis Vitkup, Alex K Shalek, Matthew G Vander Heiden
Cancer tissue of origin constrains the growth and metabolism of metastases. Nature metabolism (2024)
Valerie Lensch, Adele Gabba, Robert Hincapie, Sachin H Bhagchandani, Ankit Basak, Mohammad Murshid Alam, Darrell J Irvine, Alex K Shalek, Jeremiah A Johnson, Neal K Devaraj, Laura L Kiessling
Glycan-costumed virus-like particles promote type 1 anti-tumor immunity. bioRxiv : the preprint server for biology (2024)
Ruixu Huang, Caroline Elisabeth Kratka, Jeffrey Pea, Cai McCann, Jack Nelson, John P Bryan, Luhan Tracy Zhou, Daniela D Russo, Emily J Zaniker, Achla H Gandhi, Alex K Shalek, Brian Cleary, Samouil L Farhi, Francesca E Duncan, Brittany A Goods
Single-cell and spatiotemporal profile of ovulation in the mouse ovary. bioRxiv : the preprint server for biology (2024)
Carly G K Ziegler, Anna H Owings, Michelle Galeas-Pena, Samuel W Kazer, Vincent N Miao, Andrew W Navia, Ying Tang, Joshua D Bromley, Peter Lotfy, Meredith Sloan, Hannah Laird, Haley B Williams, Micayla George, Riley S Drake, Yilianys Pride, George E Abraham, Michal Senitko, Tanya O Robinson, Gill Diamond, Michail S Lionakis, Alex K Shalek, José Ordovas-Montañes, Bruce H Horwitz, Sarah Camille Glover
An enhanced IL17 and muted type I interferon nasal epithelial cell state characterizes severe COVID-19 with fungal coinfection. Microbiology spectrum 12 (6) (2024)
James Kaminski, Ryan A Fleming, Francesca Alvarez Calderon, Marlana B Winschel, Connor McGuckin, Emily E Ho, Fay Eng, Xianliang Rui, Paula Keskula, Lorenzo Cagnin, Joanne Charles, Jillian Zavistaski, Steven P Margossian, Malika A Kapadia, James B Rottman, Jennifer Lane, Susanne H C Baumeister, Victor Tkachev, Alex K Shalek, Leslie S Kean, Ulrike Gerdemann
B-cell-directed CAR T-cell therapy activates CD8+ cytotoxic CARneg bystander T cells in patients and nonhuman primates. Blood 144 (1) (2024)
Peter S Winter, Michelle L Ramseier, Andrew W Navia, Sachit D Saksena, Haley Strouf, Nezha Senhaji, Alan DenAdel, Mahnoor Mirza, Hyun Hwan An, Laura Bilal, Peter Dennis, Catharine S Leahy, Kay Shigemori, Jennyfer Galves-Reyes, Ye Zhang, Foster Powers, Nolawit Mulugeta, Alejandro J Gupta, Nicholas L Calistri, Alexandria Van Scoyk, Kristen Jones, Huiyun Liu, Kristen E Stevenson, Siyang Ren, Marlise R Luskin, Charles P Couturier, Ava P Soleimany, Srivatsan Raghavan, Robert J Kimmerling, Mark M Stevens, Lorin Crawford, David M Weinstock, Scott R Manalis, Alex K Shalek, Mark A Murakami
Mutation and cell state compatibility is required and targetable in Ph + acute lymphoblastic leukemia minimal residual disease. bioRxiv : the preprint server for biology (2024)
Chibuikem Nwizu, Madeline Hughes, Michelle L Ramseier, Andrew W Navia, Alex K Shalek, Nicolo Fusi, Srivatsan Raghavan, Peter S Winter, Ava P Soleimany, Lorin Crawford
Scalable nonparametric clustering with unified marker gene selection for single-cell RNA-seq data. bioRxiv : the preprint server for biology (2024)
Chibuikem Nwizu, Madeline Hughes, Michelle L Ramseier, Andrew W Navia, Alex K Shalek, Nicolo Fusi, Srivatsan Raghavan, Peter S Winter, Ava P Soleimany, Lorin Crawford
Scalable nonparametric clustering with unified marker gene selection for single-cell RNA-seq data. bioRxiv : the preprint server for biology (2024)
Joachim De Jonghe, James W Opzoomer, Amaia Vilas-Zornoza, Peter Crane, Benedikt S Nilges, Marco Vicari, Hower Lee, David Lara-Astiaso, Torsten Gross, Jörg Morf, Kim Schneider, Juliana Cudini, Lorenzo Ramos-Mucci, Dylan Mooijman, Katarína Tiklová, Sergio Marco Salas, Christoffer Mattsson Langseth, Nachiket D Kashikar, Charles E S Roberts, null null, Joakim Lundeberg, Mats Nilsson, Alex K Shalek, Adam P Cribbs, Jake P Taylor-King
A community effort to track commercial single-cell and spatial 'omic technologies and business trends. Nature biotechnology 42 (7) (2024)
Valerie Lensch, Adele Gabba, Robert Hincapie, Sachin H Bhagchandani, Ankit Basak, Mohammad Murshid Alam, Jeffery Noble, Darrell J Irvine, Alex K Shalek, Jeremiah A Johnson, Neal K Devaraj, Laura L Kiessling
Carbohydrate-Lectin Interactions Reprogram Dendritic Cells to Promote Type 1 Anti-Tumor Immunity. ACS nano (2024)
Robert Krause, Paul Ogongo, Liku Tezera, Mohammed Ahmed, Ian Mbano, Mark Chambers, Abigail Ngoepe, Magalli Magnoumba, Daniel Muema, Farina Karim, Khadija Khan, Kapongo Lumamba, Kievershen Nargan, Rajhmun Madansein, Adrie J C Steyn, Alex K Shalek, Paul Elkington, Alasdair Leslie
B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles. Communications biology 7 (1) (2024)
Peter S Winter, Michelle L Ramseier, Andrew W Navia, Sachit D Saksena, Haley Strouf, Nezha Senhaji, Alan DenAdel, Mahnoor Mirza, Hyun Hwan An, Laura Bilal, Peter Dennis, Catharine S Leahy, Kay Shigemori, Jennyfer Galves-Reyes, Ye Zhang, Foster Powers, Nolawit Mulugeta, Alejandro J Gupta, Nicholas L Calistri, Alexandria Van Scoyk, Kristen Jones, Huiyun Liu, Kristen E Stevenson, Siyang Ren, Marlise R Luskin, Charles P Couturier, Ava P Soleimany, Srivatsan Raghavan, Robert J Kimmerling, Mark M Stevens, Lorin Crawford, David M Weinstock, Scott R Manalis, Alex K Shalek, Mark A Murakami
Mutation and cell state compatibility is required and targetable in Ph + acute lymphoblastic leukemia minimal residual disease. bioRxiv : the preprint server for biology (2024)
Adam J Rubin, Tyler T Dao, Amelia V Schueppert, Aviv Regev, Alex K Shalek
LAT encodes T cell activation pathway balance. bioRxiv : the preprint server for biology (2024)
Ruixu Huang, Caroline Elisabeth Kratka, Jeffrey Pea, Cai McCann, Jack Nelson, John P Bryan, Luhan Tracy Zhou, Daniela D Russo, Emily J Zaniker, Achla H Gandhi, Alex K Shalek, Brian Cleary, Samouil L Farhi, Francesca E Duncan, Brittany A Goods
Single-cell and spatiotemporal profile of ovulation in the mouse ovary. bioRxiv : the preprint server for biology (2024)
Peter S Winter, Michelle L Ramseier, Andrew W Navia, Sachit D Saksena, Haley Strouf, Nezha Senhaji, Alan DenAdel, Mahnoor Mirza, Hyun Hwan An, Laura Bilal, Peter Dennis, Catharine S Leahy, Kay Shigemori, Jennyfer Galves-Reyes, Ye Zhang, Foster Powers, Nolawit Mulugeta, Alejandro J Gupta, Nicholas L Calistri, Alexandria Van Scoyk, Kristen Jones, Huiyun Liu, Kristen E Stevenson, Siyang Ren, Marlise R Luskin, Charles P Couturier, Ava P Soleimany, Srivatsan Raghavan, Robert J Kimmerling, Mark M Stevens, Lorin Crawford, David M Weinstock, Scott R Manalis, Alex K Shalek, Mark A Murakami
Mutation and cell state compatibility is required and targetable in Ph+ acute lymphoblastic leukemia minimal residual disease. bioRxiv : the preprint server for biology (2024)
Robert Krause, Paul Ogongo, Liku Tezera, Mohammed Ahmed, Ian Mbano, Mark Chambers, Abigail Ngoepe, Magalli Magnoumba, Daniel Muema, Farina Karim, Khadija Khan, Kapongo Lumamba, Kievershen Nargan, Rajhmun Madansein, Adrie J C Steyn, Alex K Shalek, Paul Elkington, Alasdair Leslie
B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles. Communications biology 7 (1) (2024)
Carly G K Ziegler, Anna H Owings, Michelle Galeas-Pena, Samuel W Kazer, Vincent N Miao, Andrew W Navia, Ying Tang, Joshua D Bromley, Peter Lotfy, Meredith Sloan, Hannah Laird, Haley B Williams, Micayla George, Riley S Drake, Yilianys Pride, George E Abraham, Michal Senitko, Tanya O Robinson, Gill Diamond, Michail S Lionakis, Alex K Shalek, José Ordovas-Montañes, Bruce H Horwitz, Sarah Camille Glover
An enhanced IL17 and muted type I interferon nasal epithelial cell state characterizes severe COVID-19 with fungal coinfection. Microbiology spectrum (2024)
James Kaminski, Ryan A Fleming, Francesca Alvarez Calderon, Marlana B Winschel, Connor McGuckin, Emily Elizabeth Ho, Fay Eng, Xianliang Rui, Paula Keskula, Lorenzo Cagnin, Joanne Charles, Jillian M Zavistaski, Steven P Margossian, Malika Kapadia, James B Rottman, Jennifer Lane, Susanne H C Baumeister, Victor Tkachev, Alex K Shalek, Leslie S Kean, Ulrike Gerdemann
B-cell-directed CAR-T cell therapy activates CD8+ cytotoxic CARneg bystander T-cells in non-human primates and patients. Blood (2024)
Constantine N Tzouanas, Marc S Sherman, Jessica E S Shay, Adam J Rubin, Benjamin E Mead, Tyler T Dao, Titus Butzlaff, Miyeko D Mana, Kellie E Kolb, Chad Walesky, Brian J Pepe-Mooney, Colton J Smith, Sanjay M Prakadan, Michelle L Ramseier, Evelyn Y Tong, Julia Joung, Fangtao Chi, Thomas McMahon-Skates, Carolyn L Winston, Woo-Jeong Jeong, Katherine J Aney, Ethan Chen, Sahar Nissim, Feng Zhang, Vikram Deshpande, Georg M Lauer, Ömer H Yilmaz, Wolfram Goessling, Alex K Shalek
Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival. bioRxiv : the preprint server for biology (2023)
Timothy A Gondré-Lewis, Chao Jiang, Mandy L Ford, David M Koelle, Alessandro Sette, Alex K Shalek, Paul Glyndwr Thomas
NIAID workshop on T cell technologies. Nature immunology 24 (1) (2023)
Sachin H Bhagchandani, Farrukh Vohidov, Lauren E Milling, Evelyn Yuzhou Tong, Christopher M Brown, Michelle L Ramseier, Bin Liu, Timothy B Fessenden, Hung V-T Nguyen, Gavin R Kiel, Lori Won, Robert S Langer, Stefani Spranger, Alex K Shalek, Darrell J Irvine, Jeremiah A Johnson
Engineering kinetics of TLR7/8 agonist release from bottlebrush prodrugs enables tumor-focused immune stimulation. Science advances 9 (16) (2023)
Antonio G Salazar-Martín, Aditya S Kalluri, Martin A Villanueva, Travis K Hughes, Marc H Wadsworth, Tyler T Dao, Mercedes Balcells, Farhad Rikhtegar Nezami, Alex K Shalek, Elazer R Edelman
Single-Cell RNA Sequencing Reveals Cellular Adaptation of Human Aortic Endothelial Cells to Antiproliferative Therapies Is Modulated by Flow-Induced Shear Stress. Arteriosclerosis, thrombosis, and vascular biology (2023)
Timothy A Gondré-Lewis, Chao Jiang, Mandy L Ford, David M Koelle, Alessandro Sette, Alex K Shalek, Paul Glyndwr Thomas
NIAID workshop on T cell technologies. Nature immunology 24 (1) (2023)
Aaron J Wilk, Alex K Shalek, Susan Holmes, Catherine A Blish
Comparative analysis of cell-cell communication at single-cell resolution. Nature biotechnology (2023)
Johann S Bergholz Villafane, Qiwei Wang, Qi Wang, Michelle Ramseier, Sanjay Prakadan, Weihua Wang, Rong Fang, Sheheryar K Kabraji, Qian Zhou, G Kenneth Gray, Kayley Abell-Hart, Shaozhen Xie, Xiaocan Guo, Hao Gu, Thanh Von, Tao Jiang, Shuang Tang, Gordon J Freeman, Hye-Jung Kim, Alex K Shalek, Thomas M Roberts, Jean J Zhao
PI3Kβ controls immune evasion in PTEN-deficient breast tumours. Nature (2023)
Caylin G Winchell, Sarah K Nyquist, Michael C Chao, Pauline Maiello, Amy J Myers, Forrest Hopkins, Michael R Chase, Hannah Priyadarshini Gideon, Kush V Patel, Joshua D Bromley, Andrew W Simonson, Roisin Floyd-O'Sullivan, Marc H Wadsworth, Jacob M Rosenberg, Rockib Uddin, Travis Hughes, Ryan J Kelly, Josephine Griffo, Jaime Tomko, Edwin Klein, Bonnie Berger, Charles A Scanga, Joshua T Mattila, Sarah M Fortune, Alex K Shalek, Philana Ling Lin, Joanne L Flynn
CD8+ lymphocytes are critical for early control of tuberculosis in macaques. The Journal of experimental medicine 220 (12) (2023)
Björn Corleis, Constantine N Tzouanas, Marc H Wadsworth, Josalyn L Cho, Alice H Linder, Abigail E Schiff, Björn Zessin, Fabian Stei, Anca Dorhoi, Amy K Dickey, Benjamin D Medoff, Alex K Shalek, Douglas S Kwon
Tobacco smoke exposure recruits inflammatory airspace monocytes that establish permissive lung niches for Mycobacterium tuberculosis . Science translational medicine 15 (725) (2023)
Daniel F Dwyer, José Ordovas-Montañes, Samuel J Allon, Kathleen M Buchheit, Marko Vukovic, Tahereh Derakhshan, Chunli Feng, Juying Lai, Travis K Hughes, Sarah K Nyquist, Matthew P Giannetti, Bonnie Berger, Neil Bhattacharyya, Rachel E Roditi, Howard R Katz, Martijn C Nawijn, Marijn Berg, Maarten van den Berge, Tanya M Laidlaw, Alex K Shalek, Nora A Barrett, Joshua A Boyce
Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation. Science immunology 6 (56) (2022)
Alex M Jaeger, Lauren E Stopfer, Ryuhjin Ahn, Emma A Sanders, Demi A Sandel, William A Freed-Pastor, William M Rideout, Santiago Naranjo, Tim Fessenden, Kim B Nguyen, Peter S Winter, Ryan E Kohn, Peter M K Westcott, Jason M Schenkel, Sean-Luc Shanahan, Alex K Shalek, Stefani Spranger, Forest M White, Tyler Jacks
Deciphering the immunopeptidome in vivo reveals new tumour antigens. Nature 607 (7917) (2022)
Yu-Ying Chen, Daniela D Russo, Riley S Drake, Francesca E Duncan, Alex K Shalek, Brittany A Goods, Teresa K Woodruff
Single-cell transcriptomics of staged oocytes and somatic cells reveal novel regulators of follicle activation. Reproduction (Cambridge, England) 164 (2) (2022)
Carly G K Ziegler, Anna H Owings, Vincent N Miao, Andrew W Navia, Ying Tang, Joshua D Bromley, Peter Lotfy, Meredith Sloan, Hannah Laird, Haley B Williams, Micayla George, Riley S Drake, Yilianys Pride, George E Abraham, Michal Senitko, Tanya O Robinson, Michail S Lionakis, Alex K Shalek, José Ordovas-Montañes, Bruce H Horwitz, Sarah Camille Glover
Severe COVID-19 is associated with fungal colonization of the nasopharynx and potent induction of IL-17 responses in the nasal epithelium. medRxiv : the preprint server for health sciences (2022)
Aaron J Wilk, Alex K Shalek, Susan P Holmes, Catherine A Blish
Comparative analysis of cell-cell communication at single-cell resolution. bioRxiv : the preprint server for biology (2022)
Benjamin E Mead, Kazuki Hattori, Lauren E Levy, Shinya Imada, Norihiro Goto, Marko Vukovic, Daphne Sze, Conner Kummerlowe, Juan D Matute, Jinzhi Duan, Robert S Langer, Richard S Blumberg, Jose Ordovas-Montanes, Ömer H Yilmaz, Jeffrey M Karp, Alex K Shalek
Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation. Nature biomedical engineering 6 (4) (2022)
Conner Kummerlowe, Simutanyi Mwakamui, Travis K Hughes, Nolawit Mulugeta, Victor Mudenda, Ellen Besa, Kanekwa Zyambo, Jessica E S Shay, Ira Fleming, Marko Vukovic, Benjamin A Doran, Toby P Aicher, Marc H Wadsworth, Juliet Tongue Bramante, Amiko M Uchida, Rabiah Fardoos, Osaretin E Asowata, Nicholas Herbert, Ömer H Yilmaz, Henrik N Kløverpris, John J Garber, José Ordovas-Montañes, Zev J Gartner, Thomas Wallach, Alex K Shalek, M Paul Kelly
Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation. Science translational medicine 14 (660) (2022)
Sarah K Nyquist, Patricia Gao, Tessa K J Haining, Michael R Retchin, Yarden Golan, Riley S Drake, Kellie Kolb, Benjamin E Mead, Nadav Ahituv, Micaela E Martinez, Alex K Shalek, Bonnie Berger, Brittany A Goods
Cellular and transcriptional diversity over the course of human lactation. Proceedings of the National Academy of Sciences of the United States of America 119 (15) (2022)
Hannah L Williams, Andressa Dias Costa, Jinming Zhang, Srivatsan Raghavan, Peter S Winter, Kevin S Kapner, Scott P Ginebaugh, Sara A Väyrynen, Juha P Väyrynen, Chen Yuan, Andrew W Navia, Junning Wang, Annan Yang, Timothy L Bosse, Radha L Kalekar, Kristen E Lowder, Mai Chan Lau, Dalia Elganainy, Vicente Morales-Oyarvide, Douglas A Rubinson, Harshabad Singh, Kimberley J Perez, James M Cleary, Thomas E Clancy, Jiping Wang, Joseph D Mancias, Lauren K Brais, Emma R Hill, Margaret M Kozak, David C Linehan, Richard F Dunne, Daniel T Chang, Albert C Koong, Aram F Hezel, William C Hahn, Alex K Shalek, Andrew J Aguirre, Jonathan Andrew Nowak, Brian M Wolpin
Spatially-resolved single-cell assessment of pancreatic cancer expression subtypes reveals co-expressor phenotypes and extensive intra-tumoral heterogeneity. Cancer research (2022)
Hanbing Song, Hannah N W Weinstein, Paul Allegakoen, Marc H Wadsworth, Jamie Xie, Heiko Yang, Ethan A Castro, Kevin L Lu, Bradley A Stohr, Felix Y Feng, Peter R Carroll, Bruce Wang, Matthew R Cooperberg, Alex K Shalek, Franklin W Huang
Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states. Nature communications 13 (1) (2022)
Zohreh Amoozgar, Jonas Kloepper, Jun Ren, Rong En Tay, Samuel W Kazer, Evgeny Kiner, Shanmugarajan Krishnan, Jessica M Posada, Mitrajit Ghosh, Emilie Mamessier, Christina Wong, Gino B Ferraro, Ana Batista, Nancy Wang, Mark Badeaux, Sylvie Roberge, Lei Xu, Peigen Huang, Alex K Shalek, Dai Fukumura, Hye-Jung Kim, Rakesh K Jain
Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas. Nature communications 12 (1) (2021)
Jonathan Youngs, Nicholas M Provine, Nicholas Lim, Hannah R Sharpe, Ali Amini, Yi-Ling Chen, Jian Luo, Matthew D Edmans, Panagiota Zacharopoulou, Wentao Chen, Oliver Sampson, Robert S Paton, William J Hurt, David A Duncan, Anna L McNaughton, Vincent N Miao, Susannah Leaver, Duncan L A Wyncoll, Jonathan Ball, Philip Hopkins, null null, null null, Donal T Skelly, Eleanor Barnes, Susanna J Dunachie, Graham Ogg, Teresa Lambe, Ian Douglas Pavord, Alex K Shalek, Craig P Thompson, Luzheng Xue, Derek C Macallan, Philip J R Goulder, Paul Klenerman, Tihana Bicanic
Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients. PLoS pathogens 17 (9) (2021)
Sanjay M Prakadan, Christopher A Alvarez-Breckenridge, Samuel C Markson, Albert E Kim, Robert H Klein, Naema Nayyar, Andrew W Navia, Benjamin M Kuter, Kellie E Kolb, Ivanna Bihun, Joana Liliana Mora, Mia Solana Bertalan, Brian Shaw, Michael D White, Alexander Kaplan, Jackson H Stocking, Marc H Wadsworth, Eudocia Q Lee, Ugonma Chukwueke, Nancy Wang, Megha Subramanian, Denisse Rotem, Daniel P Cahill, Viktor A Adalsteinsson, Jeffrey W Miller, Ryan J Sullivan, Scott L Carter, Priscilla Kaliopi Brastianos, Alex K Shalek
Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases. Nature communications 12 (1) (2021)
Alex S Genshaft, Carly G K Ziegler, Constantine N Tzouanas, Benjamin E Mead, Alex M Jaeger, Andrew W Navia, Ryan P King, Miyeko D Mana, Siyi Huang, Vanessa Mitsialis, Scott B Snapper, Ömer H Yilmaz, Tyler Jacks, Jeffrey F Van Humbeck, Alex K Shalek
Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes. Nature communications 12 (1) (2021)
Emilie Crouchet, Simonetta Bandiera, Naoto Fujiwara, Shen Li, Hussein El Saghire, Mirian Fernández-Vaquero, Tobias Riedl, Xiaochen Sun, Hadassa Hirschfield, Frank Jühling, Shijia Zhu, Natascha Roehlen, Clara Ponsolles, Laura Heydmann, Antonio Saviano, Tongqi Qian, Anu Venkatesh, Joachim Lupberger, Thomas F Baumert, Mozhdeh Sojoodi, Marine A Oudot, François H T Duong, Ricard Masia, Lan Wei, Christine Thumann, Sarah C Durand, Victor González-Motos, Danijela Heide, Jenny Hetzer, Shigeki Nakagawa, Atsushi Ono, Won-Min Song, Takaaki Higashi, Roberto Sanchez, Rosa S Kim, C Billie Bian, Karun Kiani, Tom Croonenborghs, Aravind Subramanian, Raymond T Chung, Beate K Straub, Detlef Schuppan, Maliki Ankavay, Laurence Cocquerel, Evelyne Schaeffer, Nicolas Goossens, Anna P Koh, Milind Mahajan, Venugopalan D Nair, Ganesh Gunasekaran, Myron E Schwartz, Nabeel El-Bardeesy, Alex K Shalek, Orit Rozenblatt-Rosen, Aviv Regev, Emanuele Felli, Patrick Pessaux, Kenneth K Tanabe, Mathias F Heikenwälder, Catherine Schuster, Nathalie Pochet, Mirjam B Zeisel, Bryan C Fuchs, Yujin Hoshida, Thomas F Baumert
A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery. Nature communications 12 (1) (2021)
Bashar Hamza, Alex B Miller, Lara Meier, Max Stockslager, Sheng Rong Ng, Emily M King, Lin Lin, Kelsey L DeGouveia, Nolawit Mulugeta, Nicholas L Calistri, Haley Strouf, Christina Bray, Felicia Rodriguez, William A Freed-Pastor, Christopher R Chin, Grissel C Jaramillo, Megan L Burger, Robert A Weinberg, Alex K Shalek, Tyler Jacks, Scott R Manalis
Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice. Nature communications 12 (1) (2021)
Joshua M Francis, Del Leistritz-Edwards, W Augustine Dunn, Christina Tarr, Jesse Lehman, Conor Dempsey, Andrew Hamel, Violeta Rayon, Gang Liu, Yuntong Wang, Marcos Wille, Melissa Durkin, Kane Hadley, Aswathy Sheena, Benjamin Roscoe, Mark Ng, Graham Rockwell, Margaret Manto, Elizabeth Gienger, Joshua Nickerson, null null, Amir Moarefi, Michael Noble, Thomas Malia, Philip D Bardwell, William Gordon, Joanna Swain, Mojca Skoberne, Karsten Sauer, Tim Harris, Ananda W Goldrath, Alex K Shalek, Anthony J Coyle, Christophe Benoist, Daniel C Pregibon, Nikolaus Jilg, Jonathan Li, Alex Rosenthal, Colline Wong, George Daley, David Golan, Howard Heller, Arlene Sharpe, Betelihem A Abayneh, Patrick Allen, Diane Antille, Katrina Armstrong, Siobhan Boyce, Joan Braley, Karen Branch, Katherine Broderick, Julia Carney, Andrew Chan, Susan Davidson, Michael Dougan, David Drew, Ashley Elliman, Keith Flaherty, Jeanne Flannery, Pamela Forde, Elise Gettings, Amanda Griffin, Sheila Grimmel, Kathleen Grinke, Kathryn Hall, Meg Healy, Deborah Henault, Grace Holland, Chantal Kayitesi, Vlasta LaValle, Yuting Lu, Sarah Luthern, Jordan Marchewka Schneider, Brittani Martino, Roseann McNamara, Christian Nambu, Susan Nelson, Marjorie Noone, Christine Ommerborn, Lois Chris Pacheco, Nicole Phan, Falisha A Porto, Edward Ryan, Kathleen Selleck, Sue Slaughenhaupt, Kimberly Smith Sheppard, Elizabeth Suschana, Vivine Wilson, Mary Carrington, Maureen Martin, Yuko Yuki, Galit Alter, Alejandro Balazs, Julia Bals, Max Barbash, Yannic Bartsch, Julie Boucau, Mary Carrington, Josh Chevalier, Fatema Chowdhury, Edward DeMers, Kevin Einkauf, Jon Fallon, Liz Fedirko, Kelsey Finn, Pilar Garcia-Broncano, Musie S Ghebremichael, Ciputra Hartana, Chenyang Jiang, Kelly Judge, Paulina Kaplonek, Marshall Karpell, Peggy Lai, Evan C Lam, Kristina Lefteri, Xiaodong Lian, Mathias Lichterfeld, Daniel Lingwood, Hang Liu, Jinqing Liu, Natasha Ly, Zachary Manickas Hill, Ashlin Michell, Ilan Millstrom, Noah Miranda, Claire O'Callaghan, Matthew Osborn, Shiv Pillai, Yelizaveta Rassadkina, Alexandra Reissis, Francis Ruzicka, Kyra Seiger, Libera Sessa, Christianne Sharr, Sally Shin, Nishant Singh, Weiwei Sun, Xiaoming Sun, Hannah Ticheli, Alicja Trocha-Piechocka, Bruce Walker, Daniel Worrall, Xu G Yu, Alex Zhu
Allelic variation in class I HLA determines CD8+ T cell repertoire shape and cross-reactive memory responses to SARS-CoV-2. Science immunology (2021)
Toni Marie Delorey, Carly G K Ziegler, Graham Heimberg, Rachelly Normand, Yiming Yang, Åsa Segerstolpe, Domenic Abbondanza, Stephen J Fleming, Ayshwarya Subramanian, Daniel T Montoro, Karthik A Jagadeesh, Kushal K Dey, Pritha Sen, Michal Slyper, Yered H Pita-Juárez, Devan Phillips, Jana Biermann, Zohar Bloom-Ackermann, Nikolaos Barkas, Andrea Ganna, James Gomez, Johannes C Melms, Igor Katsyv, Erica Normandin, Pourya Naderi, Yury V Popov, Siddharth S Raju, Sebastian Niezen, Linus T-Y Tsai, Katherine J Siddle, Malika Sud, Victoria M Tran, Shamsudheen K Vellarikkal, Yiping Wang, Liat Amir-Zilberstein, Deepak S Atri, Joseph Beechem, Olga R Brook, Jonathan Chen, Prajan Divakar, Phylicia Dorceus, Jesse M Engreitz, Adam Essene, Donna M Fitzgerald, Robin Fropf, Steven Gazal, Joshua Gould, John Grzyb, Tyler Harvey, Jonathan Hecht, Tyler Hether, Judit Jané-Valbuena, Michael Leney-Greene, Hui Ma, Cristin McCabe, Daniel E McLoughlin, Eric M Miller, Christoph Muus, Mari Niemi, Robert Padera, Liuliu Pan, Deepti Pant, Carmel Pe'er, Jenna Pfiffner-Borges, Christopher J Pinto, Jacob Plaisted, Jason Reeves, Marty Ross, Melissa Rudy, Erroll H Rueckert, Michelle Siciliano, Alexander Sturm, Ellen Todres, Avinash Waghray, Sarah Warren, Shuting Zhang, Daniel R Zollinger, Lisa Cosimi, Rajat M Gupta, Nir Hacohen, Hanina Hibshoosh, Winston Hide, Alkes L Price, Jayaraj Rajagopal, Purushothama Rao Tata, Stefan Riedel, Gyongyi Szabo, Timothy L Tickle, Patrick T Ellinor, Deborah Hung, Pardis C Sabeti, Richard Novak, Robert Rogers, Donald E Ingber, Z Gordon Jiang, Dejan Juric, Mehrtash Babadi, Samouil L Farhi, Benjamin Izar, James R Stone, Ioannis S Vlachos, Isaac H Solomon, Orr Ashenberg, Caroline B M Porter, Bo Li, Alex K Shalek, Alexandra-Chloé Villani, Orit Rozenblatt-Rosen, Aviv Regev
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets. Nature 595 (7865) (2021)
Sanjay M Prakadan, Christopher A Alvarez-Breckenridge, Samuel C Markson, Albert E Kim, Robert H Klein, Naema Nayyar, Andrew W Navia, Benjamin M Kuter, Kellie E Kolb, Ivanna Bihun, Joana Liliana Mora, Mia Solana Bertalan, Brian Shaw, Michael D White, Alexander Kaplan, Jackson H Stocking, Marc H Wadsworth, Eudocia Q Lee, Ugonma Chukwueke, Nancy Wang, Megha Subramanian, Denisse Rotem, Daniel P Cahill, Viktor A Adalsteinsson, Jeffrey W Miller, Ryan J Sullivan, Scott L Carter, Priscilla Kaliopi Brastianos, Alex K Shalek
Author Correction: Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases. Nature communications 12 (1) (2021)
Michael H Askenase, Brittany A Goods, Hannah E Beatty, Arthur F Steinschneider, Sofia E Velazquez, Artem Osherov, Margaret J Landreneau, Shaina L Carroll, Tho B Tran, Victor S Avram, Riley S Drake, G James Gatter, Jordan A Massey, Saravanan S Karuppagounder, Rajiv R Ratan, Charles C Matouk, Kevin Navin Sheth, Wendy C Ziai, Adrian R Parry-Jones, Issam A Awad, Mario Zuccarello, Richard E Thompson, Jesse Dawson, Daniel F Hanley, John Christopher Love, Alex K Shalek, Lauren Hachmann Sansing, null null, null null, null null
Longitudinal transcriptomics define the stages of myeloid activation in the living human brain after intracerebral hemorrhage. Science immunology 6 (56) (2021)
Johanne T Jacobsen, Wei Hu, Tiago Rezende de Castro, Sigrid Solem, Alice Galante, Zeran Lin, Samuel J Allon, Luka Mesin, Angelina M Bilate, Ariën Schiepers, Alex K Shalek, Alexander Y Rudensky, Gabriel D Victora
Expression of Foxp3 by T follicular helper cells in end-stage germinal centers. Science (New York, N.Y.) 373 (6552) (2021)
Victor Tkachev, James Kaminski, E Lake Potter, Scott N Furlan, Alison Yu, Daniel J Hunt, Connor McGuckin, Hengqi Betty Zheng, Lucrezia Colonna, Ulrike Gerdemann, Judith Carlson, Michelle Hoffman, Joe Olvera, Chris English, Audrey Baldessari, Angela Panoskaltsis-Mortari, Benjamin K Watkins, Muna Qayed, Yvonne Suessmuth, Kayla Betz, Brandi Bratrude, Amelia A Langston, John T Horan, José Ordovas-Montañes, Alex K Shalek, Bruce R Blazar, Mario Roederer, Leslie S Kean
Spatiotemporal single-cell profiling reveals that invasive and tissue-resident memory donor CD8+ T cells drive gastrointestinal acute graft-versus-host disease. Science translational medicine 13 (576) (2021)
Alex S Genshaft, Carly G K Ziegler, Constantine N Tzouanas, Benjamin E Mead, Alex M Jaeger, Andrew W Navia, Ryan P King, Miyeko D Mana, Siyi Huang, Vanessa Mitsialis, Scott B Snapper, Ömer H Yilmaz, Tyler Jacks, Jeffrey F Van Humbeck, Alex K Shalek
Publisher Correction: Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes. Nature communications 12 (1) (2021)
Feiyang Ma, Travis K Hughes, Rosane M B Teles, Priscila R Andrade, Bruno J de Andrade Silva, Olesya Plazyo, Lam C Tsoi, Tran Do, Marc H Wadsworth, Aislyn Oulee, Maria Teresa Ochoa, Euzenir N Sarno, M Luisa Iruela-Arispe, Eynav Klechevsky, Bryan Bryson, Alex K Shalek, Barry R Bloom, Johann E Gudjonsson, Matteo Pellegrini, Robert L Modlin
The cellular architecture of the antimicrobial response network in human leprosy granulomas. Nature immunology 22 (7) (2021)
Chad M Walesky, Kellie E Kolb, Carolyn L Winston, Jake Henderson, Benjamin Kruft, Ira Fleming, Sungjin Ko, Satdarshan Paul Monga, Florian Mueller, Udayan Apte, Alex K Shalek, Wolfram Goessling
Functional compensation precedes recovery of tissue mass following acute liver injury. Nature communications 11 (1) (2020)
Samuel W Kazer, Toby P Aicher, Daniel M Muema, Shaina L Carroll, Jose Ordovas-Montanes, Vincent N Miao, Ang A Tu, Carly G K Ziegler, Sarah K Nyquist, Emily B Wong, Nasreen Ismail, Mary Dong, Amber Moodley, Bonnie Berger, John Christopher Love, Krista L Dong, Alasdair Leslie, Zaza Mtine Ndhlovu, Thumbi Ndung'u, Bruce D Walker, Alex K Shalek
Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection. Nature medicine 26 (4) (2020)
José Ordovas-Montañes, Semir Beyaz, Seth Rakoff-Nahoum, Alex K Shalek
Distribution and storage of inflammatory memory in barrier tissues. Nature reviews. Immunology 20 (5) (2020)
Partha P Majumder, Musa M Mhlanga, Alex K Shalek
The Human Cell Atlas and equity: lessons learned. Nature medicine 26 (10) (2020)
Emily Berger, Deniz Yorukoglu, Lillian Zhang, Sarah K Nyquist, Alex K Shalek, Manolis Kellis, Ibrahim Numanagić, Bonnie Berger
Improved haplotype inference by exploiting long-range linking and allelic imbalance in RNA-seq datasets. Nature communications 11 (1) (2020)
Jiarui Ding, Xian Adiconis, Sean K Simmons, Monika S Kowalczyk, Cynthia C Hession, Nemanja D Marjanovic, Travis K Hughes, Marc H Wadsworth, Tyler Burks, Lan T Nguyen, John Y H Kwon, Boaz Barak, William Ge, Amanda J Kedaigle, Shaina Carroll, Shuqiang Li, Nir Hacohen, Orit Rozenblatt-Rosen, Alex K Shalek, Alexandra-Chloé Villani, Aviv Regev, Joshua Z Levin
Systematic comparison of single-cell and single-nucleus RNA-sequencing methods. Nature biotechnology 38 (6) (2020)
Zaza Mtine Ndhlovu, Samuel W Kazer, Thandeka Nkosi, Funsho Ogunshola, Daniel M Muema, Gursev Anmole, Shayda A Swann, Amber Moodley, Krista L Dong, Tarylee Reddy, Mark A Brockman, Alex K Shalek, Thumbi Ndung'u, Bruce D Walker
Augmentation of HIV-specific T cell function by immediate treatment of hyperacute HIV-1 infection. Science translational medicine 11 (493) (2020)
Jocelyn R Farmer, Hugues Allard-Chamard, Na Sun, Maimuna Ahmad, Alice Bertocchi, Vinay S Mahajan, Toby P Aicher, Johan Arnold, Mark D Benson, Jordan E Morningstar, Sara Barmettler, Grace J Yuen, Samuel J H Murphy, Jolan Eszter Walter, Musie Ghebremichael, Alex K Shalek, Facundo D Batista, Robert Gerszten, Shiv S Pillai
Induction of metabolic quiescence defines the transitional to follicular B cell switch. Science signaling 12 (604) (2019)
Chen Lossos, Yunpeng Liu, Kellie E Kolb, Amanda L Christie, Alexandria Van Scoyk, Sanjay M Prakadan, Kay Shigemori, Kristen E Stevenson, Sara Morrow, Olivia D Plana, Cameron Fraser, Kristen L Jones, Huiyun Liu, Christian P Pallasch, Rebecca Modiste, Quang-De Nguyen, Jeffrey W Craig, Elizabeth A Morgan, Francisco Vega, Jon C Aster, Kristopher A Sarosiek, Alex K Shalek, Michael T Hemann, David M Weinstock
Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents. Cancer discovery 9 (7) (2019)
Alexander M Tsankov, Marc H Wadsworth, Veronika Akopian, Jocelyn Charlton, Samuel J Allon, Aleksandra Arczewska, Benjamin E Mead, Riley S Drake, Zachary D Smith, Tarjei S Mikkelsen, Alex K Shalek, Alexander Meissner
Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression. Development (Cambridge, England) 146 (19) (2019)
Bashar Hamza, Sheng Rong Ng, Sanjay M Prakadan, Francisco Feijó Delgado, Christopher R Chin, Emily M King, Lucy F Yang, Shawn M Davidson, Kelsey L DeGouveia, Nathan Cermak, Andrew W Navia, Peter S Winter, Riley S Drake, Tuomas Tammela, Carman Man-Chung Li, Thales Papagiannakopoulos, Alejandro J Gupta, Josephine Shaw Bagnall, Scott M Knudsen, Matthew G Vander Heiden, Steven C Wasserman, Tyler Jacks, Alex K Shalek, Scott R Manalis
Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer. Proceedings of the National Academy of Sciences of the United States of America 116 (6) (2019)
Ang A Tu, Todd M Gierahn, Brinda Monian, Duncan M Morgan, Naveen K Mehta, Bert Ruiter, Wayne G Shreffler, Alex K Shalek, John Christopher Love
TCR sequencing paired with massively parallel 3' RNA-seq reveals clonotypic T cell signatures. Nature immunology 20 (12) (2019)
Alex K Shalek, Mikael Benson
Single-cell analyses to tailor treatments. Science translational medicine 9 (408) (2018)

Alex K Shalek.css-eqlu8i{font-size:small;padding-left:4px;} (Alex Shalek)

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Alex K Shalek (Alex Shalek)