Tyler Jacks

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 50

Top Topics

Squamous Cell Carcinoma

Brain Metastases

Top Venues

Science advances

Nature communications

Research square

This page only lists publications with an associated author ORCID identifier.

Publications

Norihiro Goto, Peter M K Westcott, Saori Goto, Shinya Imada, Martin S Taylor, George Eng, Jonathan Braverman, Vikram Deshpande, Tyler Jacks, Judith Agudo, Ömer H Yilmaz
SOX17 enables immune evasion of early colorectal adenomas and cancers. Nature 627 (8004) (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature (2024)
Sean-Luc Shanahan, Nikesh Kunder, Charles Inaku, Natalie B Hagan, Grace Gibbons, Nicolas Mathey-Andrews, Gayathri Anandappa, Shawn Soares, Kristen E Pauken, Tyler Jacks, Jason M Schenkel
Longitudinal Intravascular Antibody Labeling Identified Regulatory T Cell Recruitment as a Therapeutic Target in a Mouse Model of Lung Cancer. Journal of immunology (Baltimore, Md. : 1950) (2024)
Qian Zhong, Edward Kah Wei Tan, Carmen Martin-Alonso, Tiziana Parisi, Liangliang Hao, Jesse D Kirkpatrick, Tarek Fadel, Sangeeta N Bhatia, Tyler Jacks, Sangeeta N Bhatia
Inhalable point-of-care urinary diagnostic platform. Science advances 10 (1) (2024)
Carina Shiau, Jingyi Cao, Dennis Gong, Mark T Gregory, Nicholas J Caldwell, Xunqin Yin, Jae-Won Cho, Peter L Wang, Jennifer Su, Steven Wang, Jason W Reeves, Tae Kyung Kim, Youngmi Kim, Jimmy A Guo, Nicole A Lester, Jung Woo Bae, Ryan Zhao, Nathan Schurman, Jamie L Barth, Maria L Ganci, Ralph Weissleder, Tyler Jacks, Motaz Qadan, Theodore S Hong, Jennifer Y Wo, Hannah Roberts, Joseph M Beechem, Carlos Fernandez-Del Castillo, Mari A Mino-Kenudson, David Tsai Ting, Martin Hemberg, William L Hwang
Spatially resolved analysis of pancreatic cancer identifies therapy-associated remodeling of the tumor microenvironment. Nature genetics (2024)
E Alejandro Sweet-Cordero, Kieren Marini, Emma Champion, Alex Lee, Isabelle Young, Stanley Leung, Nicolas Mathey-Andrews, Tyler Jacks, Peter K Jackson, Jennifer R Cochran
The CLCF1-CNTFR axis drives an immunosuppressive tumor microenvironment and blockade enhances the effects of established cancer therapies. Research square (2024)
Norihiro Goto, Peter M K Westcott, Saori Goto, Shinya Imada, Martin S Taylor, George Eng, Jonathan Braverman, Vikram Deshpande, Tyler Jacks, Judith Agudo, Ömer H Yilmaz
SOX17 enables immune evasion of early colorectal adenomas and cancers. Nature 627 (8004) (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human hematopoiesis. Nature (2024)
Norihiro Goto, Peter M K Westcott, Saori Goto, Shinya Imada, Martin S Taylor, George Eng, Jonathan Braverman, Vikram Deshpande, Tyler Jacks, Judith Agudo, Ömer H Yilmaz
SOX17 enables immune evasion of early colorectal adenomas and cancers. Nature 627 (8004) (2024)
Norihiro Goto, Peter M K Westcott, Saori Goto, Shinya Imada, Martin S Taylor, George Eng, Jonathan Braverman, Vikram Deshpande, Tyler Jacks, Judith Agudo, Ömer H Yilmaz
SOX17 enables immune evasion of early colorectal adenomas and cancers. Nature (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature 627 (8003) (2024)
Qian Zhong, Edward Kah Wei Tan, Carmen Martin-Alonso, Tiziana Parisi, Liangliang Hao, Jesse D Kirkpatrick, Tarek Fadel, Sangeeta N Bhatia, Tyler Jacks, Sangeeta N Bhatia
Inhalable point-of-care urinary diagnostic platform. Science advances 10 (1) (2024)
E Alejandro Sweet-Cordero, Kieren Marini, Emma Champion, Alex Lee, Isabelle Young, Stanley Leung, Nicolas Mathey-Andrews, Tyler Jacks, Peter K Jackson, Jennifer R Cochran
The CLCF1-CNTFR axis drives an immunosuppressive tumor microenvironment and blockade enhances the effects of established cancer therapies. Research square (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human hematopoiesis. Nature (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human hematopoiesis. Nature (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature 627 (8003) (2024)
Qian Zhong, Edward Kah Wei Tan, Carmen Martin-Alonso, Tiziana Parisi, Liangliang Hao, Jesse D Kirkpatrick, Tarek Fadel, Sangeeta N Bhatia, Tyler Jacks, Sangeeta N Bhatia
Inhalable point-of-care urinary diagnostic platform. Science advances 10 (1) (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature 627 (8003) (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature 627 (8003) (2024)
Norihiro Goto, Peter M K Westcott, Saori Goto, Shinya Imada, Martin S Taylor, George Eng, Jonathan Braverman, Vikram Deshpande, Tyler Jacks, Judith Agudo, Ömer H Yilmaz
SOX17 enables immune evasion of early colorectal adenomas and cancers. Nature (2024)
Qian Zhong, Edward Kah Wei Tan, Carmen Martin-Alonso, Tiziana Parisi, Liangliang Hao, Jesse D Kirkpatrick, Tarek Fadel, Sangeeta N Bhatia, Tyler Jacks, Sangeeta N Bhatia
Inhalable point-of-care urinary diagnostic platform. Science advances 10 (1) (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature 627 (8003) (2024)
Qian Zhong, Edward Kah Wei Tan, Carmen Martin-Alonso, Tiziana Parisi, Liangliang Hao, Jesse D Kirkpatrick, Tarek Fadel, Sangeeta N Bhatia, Tyler Jacks, Sangeeta N Bhatia
Inhalable point-of-care urinary diagnostic platform. Science advances 10 (1) (2024)
Jesse S Boehm, Tyler Jacks
Radical Collaboration: Reimagining Cancer Team Science. Cancer discovery 14 (4) (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature (2024)
Norihiro Goto, Peter M K Westcott, Saori Goto, Shinya Imada, Martin S Taylor, George Eng, Jonathan Braverman, Vikram Deshpande, Tyler Jacks, Judith Agudo, Ömer H Yilmaz
SOX17 enables immune evasion of early colorectal adenomas and cancers. Nature 627 (8004) (2024)
Jesse S Boehm, Tyler Jacks
Radical Collaboration: Reimagining Cancer Team Science. Cancer discovery 14 (4) (2024)
E Alejandro Sweet-Cordero, Kieren Marini, Emma Champion, Alex Lee, Isabelle Young, Stanley Leung, Nicolas Mathey-Andrews, Tyler Jacks, Peter K Jackson, Jennifer R Cochran
The CLCF1-CNTFR axis drives an immunosuppressive tumor microenvironment and blockade enhances the effects of established cancer therapies. Research square (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature 627 (8003) (2024)
Jesse S Boehm, Tyler Jacks
Radical Collaboration: Reimagining Cancer Team Science. Cancer discovery 14 (4) (2024)
Peter M K Westcott, Francesc Muyas, Haley Hauck, Olivia C Smith, Nathan J Sacks, Zackery A Ely, Alex M Jaeger, William M Rideout, Daniel Zhang, Arjun Bhutkar, Mary Clare Beytagh, David A Canner, Grissel C Jaramillo, Roderick T Bronson, Santiago Naranjo, Abbey Jin, Justin J Patten, Amanda M Cruz, Sean-Luc Shanahan, Isidro Cortes-Ciriano, Tyler Jacks
Mismatch repair deficiency is not sufficient to elicit tumor immunogenicity. Nature genetics (2023)
William Hill, Emilia L Lim, Clare E Weeden, Claudia S Y Lee, Marcellus Augustine, Kezhong Chen, Feng-Che Kuan, Fabio Marongiu, Edward J Evans, David Allan Moore, Felipe S Rodrigues, Oriol Pich, Bjorn Bakker, Hongui Cha, Renelle Myers, Febe van Maldegem, Jesse Boumelha, Selvaraju Veeriah, Andrew Rowan, Cristina Naceur-Lombardelli, Takahiro Karasaki, Monica Sivakumar, Swapnanil De, Deborah R Caswell, Ai Nagano, James R M Black, Carlos Martínez-Ruiz, Min Hyung Ryu, Ryan D Huff, Shijia Li, Marie-Julie Favé, Alastair Magness, Alejandro Suarez-Bonnet, Simon Lawrence Priestnall, Margreet Lüchtenborg, Katrina Lavelle, Joanna Pethick, Steven Hardy, Fiona E McRonald, Meng-Hung Lin, Clara I Troccoli, Moumita Ghosh, York E Miller, Daniel T Merrick, Robert L Keith, Maise Al Bakir, Chris Bailey, Mark S Hill, Lao H Saal, Yilun Chen, Anthony M George, Christopher Abbosh, Nnennaya Kanu, Se-Hoon Lee, Nicholas McGranahan, Christine D Berg, Peter D Sasieni, Richard S Houlston, Clare Turnbull, Stephen Lam, Phillip Awadalla, Eva Grönroos, Julian Downward, Tyler Jacks, Christopher Carlsten, Ilaria Malanchi, Allan Hackshaw, Kevin Litchfield, null null, James DeGregori, Mariam Jamal-Hanjani, Charles Swanton
Lung adenocarcinoma promotion by air pollutants. Nature 616 (7955) (2023)
Zackery A Ely, Nicolas Mathey-Andrews, Santiago Naranjo, Samuel I Gould, Kim L Mercer, Gregory A Newby, Christina M Cabana, William M Rideout, Grissel Cervantes Jaramillo, Jennifer M Khirallah, Katie Holland, Peyton B Randolph, William A Freed-Pastor, Jessie R Davis, Zachary Kulstad, Peter M K Westcott, Lin Lin, Andrew V Anzalone, Brendan L Horton, Nimisha B Pattada, Sean-Luc Shanahan, Zhongfeng Ye, Stefani Spranger, Qiaobing Xu, Francisco J Sánchez Rivera, David R Liu, Tyler Jacks
A prime editor mouse to model a broad spectrum of somatic mutations in vivo. Nature biotechnology (2023)
Rodrigo Romero, Francisco J Sánchez Rivera, Peter M K Westcott, Kim L Mercer, Arjun Bhutkar, Alexander Muir, Tania J González Robles, Swanny Lamboy Rodríguez, Laura Z Liao, Sheng Rong Ng, Leanne Li, Caterina I Colón, Santiago Naranjo, Mary Clare Beytagh, Caroline A Lewis, Peggy P Hsu, Roderick T Bronson, Matthew G Vander Heiden, Tyler Jacks
Publisher Correction: Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1. Nature cancer 1 (9) (2023)
Alex M Jaeger, Lauren E Stopfer, Ryuhjin Ahn, Emma A Sanders, Demi A Sandel, William A Freed-Pastor, William M Rideout, Santiago Naranjo, Tim Fessenden, Kim B Nguyen, Peter S Winter, Ryan E Kohn, Peter M K Westcott, Jason M Schenkel, Sean-Luc Shanahan, Alex K Shalek, Stefani Spranger, Forest M White, Tyler Jacks
Deciphering the immunopeptidome in vivo reveals new tumour antigens. Nature 607 (7917) (2022)
William L Hwang, Karthik A Jagadeesh, Jimmy A Guo, Hannah I Hoffman, Payman Yadollahpour, Jason W Reeves, Rahul Mohan, Eugene Drokhlyansky, Nicholas Van Wittenberghe, Orr Ashenberg, Samouil L Farhi, Denis Schapiro, Prajan Divakar, Eric M Miller, Daniel R Zollinger, George Eng, Jason M Schenkel, Jennifer Su, Carina Shiau, Patrick Yu, William A Freed-Pastor, Domenic Abbondanza, Arnav Mehta, Joshua Gould, Conner Lambden, Caroline B M Porter, Alexander Tsankov, Danielle Dionne, Julia Waldman, Michael S Cuoco, Lan Nguyen, Toni Marie Delorey, Devan Phillips, Jaimie L Barth, Marina Kem, Clifton Rodrigues, Debora Ciprani, Jorge Roldan, Piotr Zelga, Vjola Jorgji, Jonathan H Chen, Zackery Ely, Daniel Zhao, Kit Fuhrman, Robin Fropf, Joseph M Beechem, Jay S Loeffler, David P Ryan, Colin D Weekes, Cristina R Ferrone, Motaz Qadan, Martin J Aryee, Rakesh K Jain, Donna S Neuberg, Jennifer Y Wo, Theodore S Hong, Ramnik Xavier, Andrew J Aguirre, Orit Rozenblatt-Rosen, Mari A Mino-Kenudson, Carlos Fernandez-Del Castillo, Andrew S Liss, David Tsai Ting, Tyler Jacks, Aviv Regev
Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment. Nature genetics 54 (8) (2022)
Ava P Soleimany, Jesse D Kirkpatrick, Cathy S Wang, Alex M Jaeger, Susan Su, Santiago Naranjo, Qian Zhong, Christina M Cabana, Tyler Jacks, Sangeeta N Bhatia
Multiscale profiling of protease activity in cancer. Nature communications 13 (1) (2022)
Rupesh S Patel, Rodrigo Romero, Emma V Watson, Anthony C Liang, Megan Burger, Peter M K Westcott, Kim L Mercer, Roderick T Bronson, Eric C Wooten, Arjun Bhutkar, Tyler Jacks, Stephen J Elledge
A GATA4-regulated secretory program suppresses tumors through recruitment of cytotoxic CD8 T cells. Nature communications 13 (1) (2022)
Alex S Genshaft, Carly G K Ziegler, Constantine N Tzouanas, Benjamin E Mead, Alex M Jaeger, Andrew W Navia, Ryan P King, Miyeko D Mana, Siyi Huang, Vanessa Mitsialis, Scott B Snapper, Ömer H Yilmaz, Tyler Jacks, Jeffrey F Van Humbeck, Alex K Shalek
Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes. Nature communications 12 (1) (2021)
Bashar Hamza, Alex B Miller, Lara Meier, Max Stockslager, Sheng Rong Ng, Emily M King, Lin Lin, Kelsey L DeGouveia, Nolawit Mulugeta, Nicholas L Calistri, Haley Strouf, Christina Bray, Felicia Rodriguez, William A Freed-Pastor, Christopher R Chin, Grissel C Jaramillo, Megan L Burger, Robert A Weinberg, Alex K Shalek, Tyler Jacks, Scott R Manalis
Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice. Nature communications 12 (1) (2021)
Tongtong Zhao, Zachary D Chiang, Julia W Morriss, Lindsay M LaFave, Evan M Murray, Isabella Del Priore, Kevin Meli, Caleb A Lareau, Naeem M Nadaf, Jilong Li, Andrew Scott Earl, Evan Z Macosko, Tyler Jacks, Jason D Buenrostro, Fei Chen
Spatial genomics enables multi-modal study of clonal heterogeneity in tissues. Nature 601 (7891) (2021)
Jesse D Kirkpatrick, Andrew D Warren, Ava P Soleimany, Peter M K Westcott, Justin C Voog, Carmen Martin-Alonso, Sangeeta N Bhatia, Tuomas Tammela, Tyler Jacks, Sangeeta N Bhatia
Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling. Science translational medicine 12 (537) (2021)
Cynthia Hajal, Yoojin Shin, Leanne Li, Jean Carlos Serrano, Tyler Jacks, Roger Dale Kamm
The CCL2-CCR2 astrocyte-cancer cell axis in tumor extravasation at the brain. Science advances 7 (26) (2021)
Francisco J Sánchez Rivera, Jeremy Adam Ryan, Yadira M Soto-Feliciano, Mary Clare Beytagh, Lucius Xuan, David M Feldser, Michael T Hemann, Jesse Zamudio, Nadya Dimitrova, Anthony G Letai, Tyler Jacks
Mitochondrial apoptotic priming is a key determinant of cell fate upon p53 restoration. Proceedings of the National Academy of Sciences of the United States of America 118 (23) (2021)
Alex S Genshaft, Carly G K Ziegler, Constantine N Tzouanas, Benjamin E Mead, Alex M Jaeger, Andrew W Navia, Ryan P King, Miyeko D Mana, Siyi Huang, Vanessa Mitsialis, Scott B Snapper, Ömer H Yilmaz, Tyler Jacks, Jeffrey F Van Humbeck, Alex K Shalek
Publisher Correction: Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes. Nature communications 12 (1) (2021)
Danielle M Lussier, Elise Alspach, Jeffrey P Ward, Alexander P Miceli, Daniele Runci, J Michael White, Cedric Mpoy, Cora D Arthur, Heather N Kohlmiller, Tyler Jacks, Maxim N Artyomov, Buck E Rogers, Robert D Schreiber
Radiation-induced neoantigens broaden the immunotherapeutic window of cancers with low mutational loads. Proceedings of the National Academy of Sciences of the United States of America 118 (24) (2021)
Leanne Li, Sheng Rong Ng, Caterina I Colón, Benjamin J Drapkin, Peggy P Hsu, Zhaoqi Li, Christopher S Nabel, Caroline A Lewis, Rodrigo Romero, Kim L Mercer, Arjun Bhutkar, Sarah Phat, David T Myers, Mandar Deepak Muzumdar, Peter M K Westcott, Mary Clare Beytagh, Anna F Farago, Matthew G Vander Heiden, Nicholas J Dyson, Tyler Jacks
Identification of DHODH as a therapeutic target in small cell lung cancer. Science translational medicine 11 (517) (2020)
Steffen Boettcher, Peter Grant Miller, Rohan Sharma, Marie McConkey, Matthew Joseph Leventhal, Andrei V Krivtsov, Andrew O Giacomelli, Waihay J Wong, Jesi Kim, Sherry Chao, Kari J Kurppa, Xiaoping Yang, Kirsten Milenkowic, Frederica Piccioni, David E Root, Frank G Rücker, Yael Flamand, Donna S Neuberg, R Coleman Lindsley, Pasi A Jänne, William C Hahn, Tyler Jacks, Hartmut Döhner, Scott A Armstrong, Benjamin L Ebert
A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies. Science (New York, N.Y.) 365 (6453) (2020)
Martina Damo, Brittany Fitzgerald, Yisi Lu, Mursal Nader, Ivana William, Julie F Cheung, Kelli A Connolly, Gena G Foster, Elliot Akama-Garren, Da-Yae Lee, Greg P Chang, Vasilena Gocheva, Leah M Schmidt, Alice Boileve, Josephine H Wilson, Can Cui, Isabel Monroy, Prashanth Gokare, Peter Cabeceiras, Tyler Jacks, Nikhil S Joshi
Inducible de novo expression of neoantigens in tumor cells and mice. Nature biotechnology 39 (1) (2020)