Stephen D Roughley (Stephen Roughley)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 8

Top Venues

Communications chemistry

RSC medicinal chemistry

Nature chemistry

Chemistry (Weinheim an der Bergstrasse, Germany)

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

University of Cambridge Sep 30 1995 - Sep 30 1999

United Kingdom

PHD :: Department of Chemistry

Publications

Stephanie Wills, Ruben Sanchez-Garcia, Tim Dudgeon, Stephen D Roughley, Andy Merritt, Roderick Eliot Hubbard, James Davidson, Frank von Delft, Charlotte M Deane
Fragment Merging Using a Graph Database Samples Different Catalogue Space than Similarity Search. Journal of chemical information and modeling (2023)
S Paul Jones, James D Firth, Mary C Wheldon, Masakazu Atobe, Roderick Eliot Hubbard, David C Blakemore, Claudia De Fusco, Simon C C Lucas, Stephen D Roughley, Lewis R Vidler, Maria Ann Whatton, Alison J-A Woolford, Gail L Wrigley, Peter O'Brien
Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates. RSC medicinal chemistry 13 (12) (2022)
S Paul Jones, James D Firth, Mary C Wheldon, Masakazu Atobe, Roderick Eliot Hubbard, David C Blakemore, Claudia De Fusco, Simon C C Lucas, Stephen D Roughley, Lewis R Vidler, Maria Ann Whatton, Alison J-A Woolford, Gail L Wrigley, Peter O'Brien
Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates. RSC medicinal chemistry 13 (12) (2022)
Thomas D Downes, S Paul Jones, Hanna F Klein, Mary C Wheldon, Masakazu Atobe, Paul S Bond, James D Firth, Ngai S Chan, Laura Waddelove, Roderick Eliot Hubbard, David C Blakemore, Claudia De Fusco, Stephen D Roughley, Lewis R Vidler, Maria Ann Whatton, Alison J-A Woolford, Gail L Wrigley, Peter O'Brien
Design and Synthesis of 56 Shape-Diverse 3D Fragments. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (41) (2020)
Lisa M Baker, Anthony Aimon, James B Murray, Allan E Surgenor, Natalia Matassova, Stephen D Roughley, Patrick M Collins, Tobias Krojer, Frank von Delft, Roderick Eliot Hubbard
Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures. Communications chemistry 3 (1) (2020)
Lisa M Baker, Anthony Aimon, James B Murray, Allan E Surgenor, Natalia Matassova, Stephen D Roughley, Patrick M Collins, Tobias Krojer, Frank von Delft, Roderick Eliot Hubbard
Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures. Communications chemistry 3 (1) (2020)
Paul A Brough, Lisa Baker, Simon Bedford, Kirsten Brown, Seema Chavda, Victoria Chell, Jalanie D'Alessandro, Nicholas G M Davies, Ben Davis, Loic Le Strat, Alba T Macias, Daniel Maddox, Patrick C Mahon, Andrew J Massey, Natalia Matassova, Sean McKenna, Johannes W G Meissner, Jonathan D Moore, James B Murray, Christopher J Northfield, Charles Parry, Rachel Parsons, Stephen D Roughley, Terry Shaw, Heather Simmonite, Stephen Stokes, Allan Surgenor, Emma Stefaniak, Alan Robertson, Yikang Wang, Paul Webb, Neil Whitehead, Mike Wood
Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors of Pyruvate Dehydrogenase Kinase. Journal of medicinal chemistry 60 (6) (2017)
Sergio Ruiz-Carmona, Peter Schmidtke, F Javier Luque, Lisa Baker, Natalia Matassova, Ben Davis, Stephen D Roughley, James Murray, Rod Hubbard, Xavier Barril
Dynamic undocking and the quasi-bound state as tools for drug discovery. Nature chemistry 9 (3) (2016)

Stephen D Roughley.css-eqlu8i{font-size:small;padding-left:4px;} (Stephen Roughley)

Publication Activity (10 Years)

Top Topics

Top Venues

Stephen D Roughley (Stephen Roughley)