Peter O'Brien

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 16

Top Topics

Single Molecule

Molecular Dynamics Simulations

Respiratory Syndrome Coronavirus

Top Venues

Nature chemistry

RSC medicinal chemistry

Chemical science

Organic letters

This page only lists publications with an associated author ORCID identifier.

Publications

Petr Slavik, Benjamin R Trowse, Peter O'Brien, David K Smith
Organogel delivery vehicles for the stabilization of organolithium reagents. Nature chemistry 15 (3) (2023)
Petr Slavik, Benjamin R Trowse, Peter O'Brien, David K Smith
Organogel delivery vehicles for the stabilization of organolithium reagents. Nature chemistry (2023)
Petr Slavik, Benjamin R Trowse, Peter O'Brien, David K Smith
Organogel delivery vehicles for the stabilization of organolithium reagents. Nature chemistry 15 (3) (2023)
Petr Slavik, Benjamin R Trowse, Peter O'Brien, David K Smith
Organogel delivery vehicles for the stabilization of organolithium reagents. Nature chemistry 15 (3) (2023)
Petr Slavik, Benjamin R Trowse, Peter O'Brien, David K Smith
Author Correction: Organogel delivery vehicles for the stabilization of organolithium reagents. Nature chemistry (2023)
David J Hamilton, Marieke Beemsterboer, Caroline M Carter, Jasmina Elsayed, Rilana E M Huiberts, Hanna F Klein, Peter O'Brien, Iwan J P de Esch, Maikel Wijtmans
Puckering the Planar Landscape of Fragments: Design and Synthesis of a 3D Cyclobutane Fragment Library. ChemMedChem 17 (9) (2022)
S Paul Jones, James D Firth, Mary C Wheldon, Masakazu Atobe, Roderick Eliot Hubbard, David C Blakemore, Claudia De Fusco, Simon C C Lucas, Stephen D Roughley, Lewis R Vidler, Maria Ann Whatton, Alison J-A Woolford, Gail L Wrigley, Peter O'Brien
Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates. RSC medicinal chemistry 13 (12) (2022)
S Paul Jones, James D Firth, Mary C Wheldon, Masakazu Atobe, Roderick Eliot Hubbard, David C Blakemore, Claudia De Fusco, Simon C C Lucas, Stephen D Roughley, Lewis R Vidler, Maria Ann Whatton, Alison J-A Woolford, Gail L Wrigley, Peter O'Brien
Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates. RSC medicinal chemistry 13 (12) (2022)
Marion Schuller, Galen J Correy, Stefan Gahbauer, Daren Fearon, Taiasean Wu, Roberto Efraín Díaz, Iris D Young, Luan Carvalho Martins, Dominique H Smith, Ursula Schulze-Gahmen, Tristan W Owens, Ishan Deshpande, Gregory E Merz, Aye C Thwin, Justin T Biel, Jessica K Peters, Michelle Moritz, Nadia Herrera, Huong T Kratochvil, null null, Anthony Aimon, James M Bennett, José Brandão-Neto, Aina E Cohen, Alexandre Dias, Alice Douangamath, Louise Dunnett, Oleg Fedorov, Matteo P Ferla, Martin R Fuchs, Tyler J Gorrie-Stone, James M Holton, Michael G Johnson, Tobias Krojer, George Meigs, Ailsa J Powell, Johannes Gregor Matthias Rack, Victor L Rangel, Silvia Russi, Rachael E Skyner, Clyde A Smith, Alexei S Soares, Jennifer L Wierman, Kang Zhu, Peter O'Brien, Natalia Jura, Alan Ashworth, John J Irwin, Michael C Thompson, Jason E Gestwicki, Frank von Delft, Brian K Shoichet, Brian K Shoichet, Ivan Ahel
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking. Science advances 7 (16) (2021)
Thomas D Downes, S Paul Jones, Hanna F Klein, Mary C Wheldon, Masakazu Atobe, Paul S Bond, James D Firth, Ngai S Chan, Laura Waddelove, Roderick Eliot Hubbard, David C Blakemore, Claudia De Fusco, Stephen D Roughley, Lewis R Vidler, Maria Ann Whatton, Alison J-A Woolford, Gail L Wrigley, Peter O'Brien
Design and Synthesis of 56 Shape-Diverse 3D Fragments. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (41) (2020)
Alice Douangamath, Daren Fearon, Paul Gehrtz, Tobias Krojer, Petra Lukacik, C David Owen, Efrat Resnick, Claire Strain-Damerell, Anthony Aimon, Péter Ábrányi-Balogh, José Brandão-Neto, Anna Carbery, Gemma Davison, Alexandre Dias, Thomas D Downes, Louise Dunnett, Michael Fairhead, James D Firth, S Paul Jones, Aaron Keeley, György M Keserü, Hanna F Klein, Mathew P Martin, Martin E M Noble, Peter O'Brien, Ailsa J Powell, Rambabu N Reddi, Rachael E Skyner, Matthew Snee, Michael J Waring, Conor Wild, Nir London, Frank von Delft, Martin Austin Walsh
Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease. Nature communications 11 (1) (2020)
Hon Eong Ho, Angela Pagano, James A Rossi-Ashton, James R Donald, Ryan G Epton, Jonathan C Churchill, Michael J James, Peter O'Brien, Richard J K Taylor, William P Unsworth
Visible-light-induced intramolecular charge transfer in the radical spirocyclisation of indole-tethered ynones. Chemical science 11 (5) (2019)
Hon Eong Ho, Michael J James, Peter O'Brien, Richard J K Taylor, William P Unsworth
Ag(I)-Catalyzed Synthesis of Azabicyclic Alkaloid Frameworks from Ketimine-Tethered Ynones: Total Synthesis of Indolizidine 209D. Organic letters 20 (5) (2018)
James D Firth, Peter O'Brien, Leigh Ferris
General Procedures for the Lithiation/Trapping of N-Boc Piperazines. The Journal of organic chemistry 82 (13) (2017)
James D Firth, Steven J Canipa, Leigh Ferris, Peter O'Brien
Gram-Scale Synthesis of the (-)-Sparteine Surrogate and (-)-Sparteine. Angewandte Chemie (International ed. in English) 57 (1) (2017)
John F Darby, Masakazu Atobe, James D Firth, Paul S Bond, Gideon J Davies, Peter O'Brien, Roderick Eliot Hubbard
Increase of enzyme activity through specific covalent modification with fragments. Chemical science 8 (11) (2017)