Roderick Eliot Hubbard (Roderick E Hubbard)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 15

Top Venues

RSC medicinal chemistry

Communications chemistry

SLAS discovery : advancing life sciences R & D

Chemistry (Weinheim an der Bergstrasse, Germany)

University of York

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of York Oct 01 1980

United Kingdom

Lecturer, Reader (1990), Professor (1995) :: Chemistry

Publications

Naoki Kuki, David Lee Walmsley, Kazuo Kanai, Sho Takechi, Masao Yoshida, Ryo Murakami, Kohei Takano, Yuichi Tominaga, Mizuki Takahashi, Shuichiro Ito, Naoki Nakao, Hayley Angove, Lisa M Baker, Edward Carter, Pawel Dokurno, Loic Le Strat, Alba T Macias, Carrie-Anne Molyneaux, James B Murray, Allan E Surgenor, Tomoaki Hamada, Roderick Eliot Hubbard
A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase. RSC medicinal chemistry 14 (12) (2023)
Naoki Kuki, David Lee Walmsley, Kazuo Kanai, Sho Takechi, Masao Yoshida, Ryo Murakami, Kohei Takano, Yuichi Tominaga, Mizuki Takahashi, Shuichiro Ito, Naoki Nakao, Hayley Angove, Lisa M Baker, Edward Carter, Pawel Dokurno, Loic Le Strat, Alba T Macias, Carrie-Anne Molyneaux, James B Murray, Allan E Surgenor, Tomoaki Hamada, Roderick Eliot Hubbard
A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase. RSC medicinal chemistry 14 (12) (2023)
Stephanie Wills, Ruben Sanchez-Garcia, Tim Dudgeon, Stephen D Roughley, Andy Merritt, Roderick Eliot Hubbard, James Davidson, Frank von Delft, Charlotte M Deane
Fragment Merging Using a Graph Database Samples Different Catalogue Space than Similarity Search. Journal of chemical information and modeling (2023)
S Paul Jones, James D Firth, Mary C Wheldon, Masakazu Atobe, Roderick Eliot Hubbard, David C Blakemore, Claudia De Fusco, Simon C C Lucas, Stephen D Roughley, Lewis R Vidler, Maria Ann Whatton, Alison J-A Woolford, Gail L Wrigley, Peter O'Brien
Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates. RSC medicinal chemistry 13 (12) (2022)
S Paul Jones, James D Firth, Mary C Wheldon, Masakazu Atobe, Roderick Eliot Hubbard, David C Blakemore, Claudia De Fusco, Simon C C Lucas, Stephen D Roughley, Lewis R Vidler, Maria Ann Whatton, Alison J-A Woolford, Gail L Wrigley, Peter O'Brien
Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates. RSC medicinal chemistry 13 (12) (2022)
Huiyong Ma, James B Murray, Huadong Luo, Xuemin Cheng, Qiuxia Chen, Chao Song, Cong Duan, Ping Tan, Lifang Zhang, Jian Liu, Barry A Morgan, Jin Li, Jinqiao Wan, Lisa M Baker, William Finnie, Lucie Guetzoyan, Richard Harris, Nicole Hendrickson, Natalia Matassova, Heather Simmonite, Julia Smith, Roderick Eliot Hubbard, Guansai Liu
PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery. RSC medicinal chemistry 13 (11) (2022)
David Lee Walmsley, James B Murray, Pawel Dokurno, Andrew J Massey, Karen Benwell, Andrea Fiumana, Nicolas Foloppe, Stuart Ray, Julia Smith, Allan E Surgenor, Thomas Edmonds, Didier Demarles, Mike Burbridge, Francisco Cruzalegui, András Kotschy, Roderick Eliot Hubbard
Fragment-Derived Selective Inhibitors of Dual-Specificity Kinases DYRK1A and DYRK1B. Journal of medicinal chemistry 64 (13) (2021)
Thomas D Downes, S Paul Jones, Hanna F Klein, Mary C Wheldon, Masakazu Atobe, Paul S Bond, James D Firth, Ngai S Chan, Laura Waddelove, Roderick Eliot Hubbard, David C Blakemore, Claudia De Fusco, Stephen D Roughley, Lewis R Vidler, Maria Ann Whatton, Alison J-A Woolford, Gail L Wrigley, Peter O'Brien
Design and Synthesis of 56 Shape-Diverse 3D Fragments. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (41) (2020)
Lisa M Baker, Anthony Aimon, James B Murray, Allan E Surgenor, Natalia Matassova, Stephen D Roughley, Patrick M Collins, Tobias Krojer, Frank von Delft, Roderick Eliot Hubbard
Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures. Communications chemistry 3 (1) (2020)
Lisa M Baker, Anthony Aimon, James B Murray, Allan E Surgenor, Natalia Matassova, Stephen D Roughley, Patrick M Collins, Tobias Krojer, Frank von Delft, Roderick Eliot Hubbard
Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures. Communications chemistry 3 (1) (2020)
Darius Vagrys, James Davidson, I-Jen Chen, Roderick Eliot Hubbard, Ben Davis
Exploring IDP-Ligand Interactions: tau K18 as A Test Case. International journal of molecular sciences 21 (15) (2020)
Claire Raingeval, Olivier Cala, Béatrice Brion, Marc Le Borgne, Roderick Eliot Hubbard, Isabelle Krimm
1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery. Journal of enzyme inhibition and medicinal chemistry 34 (1) (2019)
Bas Lamoree, Roderick Eliot Hubbard
Using Fragment-Based Approaches to Discover New Antibiotics. SLAS discovery : advancing life sciences R & D 23 (6) (2019)
John F Darby, Adam P Hopkins, Seishi Shimizu, Shirley M Roberts, James A Brannigan, Johan P Turkenburg, Gavin Hugh Thomas, Roderick Eliot Hubbard, Marcus Fischer
Water Networks Can Determine the Affinity of Ligand Binding to Proteins. Journal of the American Chemical Society 141 (40) (2019)
John F Darby, Masakazu Atobe, James D Firth, Paul S Bond, Gideon J Davies, Peter O'Brien, Roderick Eliot Hubbard
Increase of enzyme activity through specific covalent modification with fragments. Chemical science 8 (11) (2017)

Roderick Eliot Hubbard.css-eqlu8i{font-size:small;padding-left:4px;} (Roderick E Hubbard)

Publication Activity (10 Years)

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Roderick Eliot Hubbard (Roderick E Hubbard)