Subra Kugathasan

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 29

Top Topics

Gene Expression

Ulcerative Colitis

Vascular Endothelial Growth Factor

Top Venues

Nature communications

Stem cells (Dayton, Ohio)

Genes and immunity

Journal of Crohn's & colitis

This page only lists publications with an associated author ORCID identifier.

Publications

Margaret Brown, Anne Dodd, Fang Shi, Emily Greenwood, Sini Nagpal, Vasantha L Kolachala, Subra Kugathasan, Greg Gibson
Concordant B and T Cell Heterogeneity Inferred from the Multiomic Landscape of Peripheral Blood Mononuclear Cells in a Crohn's Disease Cohort. Journal of Crohn's & colitis (2024)
Dominik Aschenbrenner, Isar Nassiri, Suresh Venkateswaran, Sumeet Pandey, Matthew Page, Lauren Drowley, Martin Armstrong, Subra Kugathasan, Benjamin P Fairfax, Hans Holm Uhlig
An isoform quantitative trait locus in SBNO2 links genetic susceptibility to Crohn's disease with defective antimicrobial activity. Nature communications 15 (1) (2024)
Dominik Aschenbrenner, Isar Nassiri, Suresh Venkateswaran, Sumeet Pandey, Matthew Page, Lauren Drowley, Martin Armstrong, Subra Kugathasan, Benjamin P Fairfax, Hans Holm Uhlig
An isoform quantitative trait locus in SBNO2 links genetic susceptibility to Crohn's disease with defective antimicrobial activity. Nature communications 15 (1) (2024)
Jonathan R Dillman, Jean A Tkach, Joel G Fletcher, David H Bruining, Aiming Lu, Subra Kugathasan, Adina L Alazraki, Jack Knight-Scott, Ryan W Stidham, Jeremy Adler, Bruce C Trapnell, Scott D Swanson, Lin Fei, Lucia Qian, Alexander J Towbin, Murat Kocaoglu, Christopher G Anton, Rebecca A Imbus, Jonathan A Dudley, Lee A Denson
MRI and Blood-based Biomarkers Are Associated With Surgery in Children and Adults With Ileal Crohn's Disease. Inflammatory bowel diseases (2024)
Dominik Aschenbrenner, Isar Nassiri, Suresh Venkateswaran, Sumeet Pandey, Matthew Page, Lauren Drowley, Martin Armstrong, Subra Kugathasan, Benjamin P Fairfax, Hans Holm Uhlig
An isoform quantitative trait locus in SBNO2 links genetic susceptibility to Crohn's disease with defective antimicrobial activity. Nature communications 15 (1) (2024)
Dominik Aschenbrenner, Isar Nassiri, Suresh Venkateswaran, Sumeet Pandey, Matthew Page, Lauren Drowley, Martin Armstrong, Subra Kugathasan, Benjamin P Fairfax, Hans Holm Uhlig
An isoform quantitative trait locus in SBNO2 links genetic susceptibility to Crohn's disease with defective antimicrobial activity. Nature communications 15 (1) (2024)
Tyler U Faircloth, Sara Temple, Rhett N Parr, Anna Bryce Tucker, Devi Rajan, Peiman Hematti, Subra Kugathasan, Raghavan Chinnadurai
Vascular Endothelial Growth Factor secretion and immunosuppression are distinct potency mechanisms of Human Bone Marrow Mesenchymal Stromal Cells. Stem cells (Dayton, Ohio) (2024)
Tyler U Faircloth, Sara Temple, Rhett N Parr, Anna B Tucker, Devi Rajan, Peiman Hematti, Subra Kugathasan, Raghavan Chinnadurai
Vascular endothelial growth factor secretion and immunosuppression are distinct potency mechanisms of human bone marrow mesenchymal stromal cells. Stem cells (Dayton, Ohio) 42 (8) (2024)
Yiming Wu, Kyle Gettler, Meltem Ece Kars, Mamta Giri, Dalin Li, Cigdem Sevim Bayrak, Peng Zhang, Aayushee Jain, Patrick Maffucci, Ksenija Sabic, Tielman T Van Vleck, Girish Nitin Nadkarni, Lee A Denson, Harry Ostrer, Adam P Levine, Elena R Schiff, Anthony Walter Segal, Subra Kugathasan, Peter D Stenson, David N Cooper, L Philip Schumm, Scott B Snapper, Mark J Daly, Talin Haritunians, Richard H Duerr, Mark S Silverberg, John D Rioux, Steven R Brant, Dermot P B McGovern, Judy H Cho, Yuval Itan
Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients. Nature communications 14 (1) (2023)
Yiming Wu, Kyle Gettler, Meltem Ece Kars, Mamta Giri, Dalin Li, Cigdem Sevim Bayrak, Peng Zhang, Aayushee Jain, Patrick Maffucci, Ksenija Sabic, Tielman T Van Vleck, Girish Nitin Nadkarni, Lee A Denson, Harry Ostrer, Adam P Levine, Elena R Schiff, Anthony Walter Segal, Subra Kugathasan, Peter D Stenson, David N Cooper, L Philip Schumm, Scott B Snapper, Mark J Daly, Talin Haritunians, Richard H Duerr, Mark S Silverberg, John D Rioux, Steven R Brant, Dermot P B McGovern, Judy H Cho, Yuval Itan
Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients. Nature communications 14 (1) (2023)
Murugadas Anbazhagan, Duke Geem, Suresh Venkateswaran, Ranjit Pelia, Vasantha L Kolachala, Anne Dodd, Sushma C Maddipatla, David J Cutler, Jason D Matthews, Raghavan Chinnadurai, Subra Kugathasan
Characterization of Intestinal Mesenchymal Stromal Cells From Patients With Inflammatory Bowel Disease for Autologous Cell Therapy. Stem cells translational medicine 12 (2) (2023)
Yiming Wu, Kyle Gettler, Meltem Ece Kars, Mamta Giri, Dalin Li, Cigdem Sevim Bayrak, Peng Zhang, Aayushee Jain, Patrick Maffucci, Ksenija Sabic, Tielman T Van Vleck, Girish Nitin Nadkarni, Lee A Denson, Harry Ostrer, Adam P Levine, Elena R Schiff, Anthony Walter Segal, Subra Kugathasan, Peter D Stenson, David N Cooper, L Philip Schumm, Scott B Snapper, Mark J Daly, Talin Haritunians, Richard H Duerr, Mark S Silverberg, John D Rioux, Steven R Brant, Dermot P B McGovern, Judy H Cho, Yuval Itan
Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients. Nature communications 14 (1) (2023)
Yiming Wu, Kyle Gettler, Meltem Ece Kars, Mamta Giri, Dalin Li, Cigdem Sevim Bayrak, Peng Zhang, Aayushee Jain, Patrick Maffucci, Ksenija Sabic, Tielman T Van Vleck, Girish Nitin Nadkarni, Lee A Denson, Harry Ostrer, Adam P Levine, Elena R Schiff, Anthony Walter Segal, Subra Kugathasan, Peter D Stenson, David N Cooper, L Philip Schumm, Scott B Snapper, Mark J Daly, Talin Haritunians, Richard H Duerr, Mark S Silverberg, John D Rioux, Steven R Brant, Dermot P B McGovern, Judy H Cho, Yuval Itan
Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients. Nature communications 14 (1) (2023)
Yiming Wu, Kyle Gettler, Meltem Ece Kars, Mamta Giri, Dalin Li, Cigdem Sevim Bayrak, Peng Zhang, Aayushee Jain, Patrick Maffucci, Ksenija Sabic, Tielman T Van Vleck, Girish Nitin Nadkarni, Lee A Denson, Harry Ostrer, Adam P Levine, Elena R Schiff, Anthony Walter Segal, Subra Kugathasan, Peter D Stenson, David N Cooper, L Philip Schumm, Scott B Snapper, Mark J Daly, Talin Haritunians, Richard H Duerr, Mark S Silverberg, John D Rioux, Steven R Brant, Dermot P B McGovern, Judy H Cho, Yuval Itan
Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients. Nature communications 14 (1) (2023)
Yiming Wu, Kyle Gettler, Meltem Ece Kars, Mamta Giri, Dalin Li, Cigdem Sevim Bayrak, Peng Zhang, Aayushee Jain, Patrick Maffucci, Ksenija Sabic, Tielman T Van Vleck, Girish Nitin Nadkarni, Lee A Denson, Harry Ostrer, Adam P Levine, Elena R Schiff, Anthony Walter Segal, Subra Kugathasan, Peter D Stenson, David N Cooper, L Philip Schumm, Scott B Snapper, Mark J Daly, Talin Haritunians, Richard H Duerr, Mark S Silverberg, John D Rioux, Steven R Brant, Dermot P B McGovern, Judy H Cho, Yuval Itan
Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients. Nature communications 14 (1) (2023)
Yiming Wu, Kyle Gettler, Meltem Ece Kars, Mamta Giri, Dalin Li, Cigdem Sevim Bayrak, Peng Zhang, Aayushee Jain, Patrick Maffucci, Ksenija Sabic, Tielman T Van Vleck, Girish Nitin Nadkarni, Lee A Denson, Harry Ostrer, Adam P Levine, Elena R Schiff, Anthony Walter Segal, Subra Kugathasan, Peter D Stenson, David N Cooper, L Philip Schumm, Scott B Snapper, Mark J Daly, Talin Haritunians, Richard H Duerr, Mark S Silverberg, John D Rioux, Steven R Brant, Dermot P B McGovern, Judy H Cho, Yuval Itan
Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients. Nature communications 14 (1) (2023)
Yiming Wu, Kyle Gettler, Meltem Ece Kars, Mamta Giri, Dalin Li, Cigdem Sevim Bayrak, Peng Zhang, Aayushee Jain, Patrick Maffucci, Ksenija Sabic, Tielman T Van Vleck, Girish Nitin Nadkarni, Lee A Denson, Harry Ostrer, Adam P Levine, Elena R Schiff, Anthony Walter Segal, Subra Kugathasan, Peter D Stenson, David N Cooper, L Philip Schumm, Scott B Snapper, Mark J Daly, Talin Haritunians, Richard H Duerr, Mark S Silverberg, John D Rioux, Steven R Brant, Dermot P B McGovern, Judy H Cho, Yuval Itan
Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients. Nature communications 14 (1) (2023)
Yiming Wu, Kyle Gettler, Meltem Ece Kars, Mamta Giri, Dalin Li, Cigdem Sevim Bayrak, Peng Zhang, Aayushee Jain, Patrick Maffucci, Ksenija Sabic, Tielman T Van Vleck, Girish Nitin Nadkarni, Lee A Denson, Harry Ostrer, Adam P Levine, Elena R Schiff, Anthony Walter Segal, Subra Kugathasan, Peter D Stenson, David N Cooper, L Philip Schumm, Scott B Snapper, Mark J Daly, Talin Haritunians, Richard H Duerr, Mark S Silverberg, John D Rioux, Steven R Brant, Dermot P B McGovern, Judy H Cho, Yuval Itan
Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients. Nature communications 14 (1) (2023)
Katya E Sosnovski, Tzipi Braun, Amnon Amir, Danielle Moshel, Marina BenShoshan, Kelli L VanDussen, Nina Levhar, Haya Abbas-Egbariya, Katia Beider, Rakefet Ben-Yishay, Syed Asad Ali, Sean R Moore, Subra Kugathasan, Ifat Abramovich, Efrat Glick Saar, Batya Weiss, Iris Barshack, Eyal Gottlieb, Tamar Geiger, Shomron Ben-Horin, Igor Ulitsky, Jeffrey S Hyams, Lee A Denson, Yael Haberman
GATA6-AS1 regulates intestinal epithelial mitochondrial functions, and its reduced expression is linked to intestinal inflammation and less favorable disease course in ulcerative colitis (UC). Journal of Crohn's & colitis (2023)
Hari K Somineni, Jordan H Weitzner, Suresh Venkateswaran, Anne Dodd, Jarod Prince, Arjuna Karikaran, Cary G Sauer, Shelly Abramowicz, Michael E Zwick, David J Cutler, David T Okou, Pankaj Chopra, Subra Kugathasan
Site- and Taxa-Specific Disease-Associated Oral Microbial Structures Distinguish Inflammatory Bowel Diseases. Inflammatory bowel diseases 27 (12) (2022)
Shikha Nayar, Joshua K Morrison, Mamta Giri, Kyle Gettler, Ling-Shiang Chuang, Laura A Walker, Huaibin Mabel Ko, Ephraim Kenigsberg, Subra Kugathasan, Miriam Merad, Jaime Chu, Judy H Cho
A myeloid-stromal niche and gp130 rescue in NOD2-driven Crohn's disease. Nature 593 (7858) (2021)
Sanam Soomro, Suresh Venkateswaran, Kamala Vanarsa, Marwa Kharboutli, Malavika Nidhi, Ramya Susarla, Ting Zhang, Prashanth Sasidharan, Kyung Hyun Lee, Joel Rosh, James Markowitz, Claudia Pedroza, Lee A Denson, Jeffrey Hyams, Subra Kugathasan, Chandra Mohan
Predicting disease course in ulcerative colitis using stool proteins identified through an aptamer-based screen. Nature communications 12 (1) (2021)
Ranjit Pelia, Suresh Venkateswaran, Jason D Matthews, Yael Haberman, David J Cutler, Jeffrey S Hyams, Lee A Denson, Subra Kugathasan
Profiling non-coding RNA levels with clinical classifiers in pediatric Crohn's disease. BMC medical genomics 14 (1) (2021)
Yael Haberman, Rebekah Karns, Phillip J Dexheimer, Melanie Schirmer, Judith Somekh, Ingrid Jurickova, Tzipi Braun, Elizabeth Novak, Laura Bauman, Margaret H Collins, Angela Mo, Michael J Rosen, Erin Bonkowski, Nathan Gotman, Alison Marquis, Mason Nistel, Paul A Rufo, Susan S Baker, Cary G Sauer, James Markowitz, Marian D Pfefferkorn, Joel R Rosh, Brendan M Boyle, David R Mack, Robert N Baldassano, Sapana Shah, Neal S Leleiko, Melvin B Heyman, Anne M Grifiths, Ashish S Patel, Joshua D Noe, Bruce J Aronow, Subra Kugathasan, Thomas D Walters, Greg Gibson, Sonia Davis Thomas, Kevin Mollen, Shai S Shen-Orr, Curtis Huttenhower, Ramnik J Xavier, Jeffrey S Hyams, Lee A Denson
Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response. Nature communications 10 (1) (2019)
Kyle Gettler, Mamta Giri, Ephraim Kenigsberg, Jerome Martin, Ling-Shiang Chuang, Nai-Yun Hsu, Lee A Denson, Jeffrey S Hyams, Anne Griffiths, Joshua D Noe, Wallace V Crandall, David R Mack, Richard Kellermayer, Clara Abraham, Gabriel E Hoffman, Subra Kugathasan, Judy H Cho
Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets. Genes and immunity 20 (7) (2019)
Melanie Schirmer, Eric A Franzosa, Jason Lloyd-Price, Lauren J McIver, Randall Schwager, Tiffany W Poon, Ashwin N Ananthakrishnan, Elizabeth Andrews, Gildardo Barron, Kathleen Lake, Mahadev Prasad, Jenny Sauk, Betsy Stevens, Robin G Wilson, Jonathan G Braun, Lee A Denson, Subra Kugathasan, Dermot P B McGovern, Hera Vlamakis, Ramnik J Xavier, Curtis Huttenhower
Dynamics of metatranscription in the inflammatory bowel disease gut microbiome. Nature microbiology 3 (3) (2018)
Kelly A Shaw, Kelly A Shaw, David Okou, Anne Dodd, Bruce J Aronow, Yael Haberman, Christine Stevens, Thomas D Walters, Anne Griffiths, Robert N Baldassano, Joshua D Noe, Jeffrey S Hyams, Wallace V Crandall, Barbara S Kirschner, Melvin B Heyman, Scott Snapper, Stephen Guthery, Marla C Dubinsky, Jason M Shapiro, Anthony R Otley, Mark Daly, Lee A Denson, Subra Kugathasan, Michael E Zwick
Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort. Genes and immunity 20 (2) (2018)
Urko M Marigorta, Lee A Denson, Jeffrey S Hyams, Kajari Mondal, Jarod Prince, Thomas D Walters, Anne Griffiths, Joshua D Noe, Wallace V Crandall, Joel R Rosh, David R Mack, Richard Kellermayer, Melvin B Heyman, Susan S Baker, Michael C Stephens, Robert N Baldassano, James F Markowitz, Mi-Ok Kim, Marla C Dubinsky, Judy Cho, Bruce J Aronow, Subra Kugathasan, Greg Gibson
Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease. Nature genetics 49 (10) (2017)
Kelly A Shaw, Madeline Bertha, Tatyana Hofmekler, Pankaj Chopra, Tommi Vatanen, Abhiram Srivatsa, Jarod Prince, Archana Kumar, Cary Sauer, Michael E Zwick, Glen A Satten, Aleksandar D Kostic, Jennifer G Mulle, Ramnik J Xavier, Subra Kugathasan
Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease. Genome medicine 8 (1) (2016)