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Thomas D Meek

ORCID

Publication Activity (10 Years)

Years Active: 2018-2022
Publications (10 Years): 10

Top Venues

Journal of medicinal chemistry

Biochemistry

ACS chemical biology

PLoS neglected tropical diseases

University of Virginia (BSC)

This page only lists publications with an associated author ORCID identifier.

Education History

University of Virginia

United States

BSC :: Chemistry

Publications

Kayla Glockzin, Thomas D Meek, Ardala Katzfuss
Characterization of adenine phosphoribosyltransferase (APRT) activity in Trypanosoma brucei brucei: Only one of the two isoforms is kinetically active. PLoS neglected tropical diseases 16 (2) (2022)
Anneliese S Ashhurst, Arthur H Tang, Pavla Fajtová, Michael C Yoon, Anupriya Aggarwal, Max J Bedding, Alexander Stoye, Laura Beretta, Dustin Pwee, Aleksandra Drelich, Danielle Skinner, Linfeng Li, Thomas D Meek, James H McKerrow, Vivian Hook, Chien-Te Tseng, Mark Larance, Stuart Turville, William H Gerwick, Anthony J O'Donoghue, Richard J Payne
Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L. Journal of medicinal chemistry (2021)
Drake M Mellott, Chien-Te Tseng, Aleksandra Drelich, Pavla Fajtová, Bala C Chenna, Demetrios H Kostomiris, Jason Hsu, Jiyun Zhu, Zane W Taylor, Klaudia I Kocurek, Vivian Tat, Ardala Katzfuss, Linfeng Li, Miriam A Giardini, Danielle Skinner, Ken Hirata, Michael C Yoon, Sungjun Beck, Aaron F Carlin, Alex E Clark, Laura Beretta, Daniel Maneval, Vivian Hook, Felix Frueh, Brett L Hurst, Hong Wang, Frank M Raushel, Anthony J O'Donoghue, Jair Lage de Siqueira-Neto, Thomas D Meek, James H McKerrow
A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells. ACS chemical biology 16 (4) (2021)
Truc Viet Pham, Drake M Mellott, Zahra Moghadamchargari, Kevin Chen, Inna Krieger, Arthur D Laganowsky, James C Sacchettini, Thomas D Meek
Covalent Inactivation of Mycobacterium tuberculosis Isocitrate Lyase by cis-2,3-Epoxy-Succinic Acid. ACS chemical biology 16 (3) (2021)
Drake M Mellott, Dan Torres, Inna V Krieger, Scott A Cameron, Zahra Moghadamchargari, Arthur D Laganowsky, James C Sacchettini, Thomas D Meek, Lawrence D Harris
Mechanism-Based Inactivation of Mycobacterium tuberculosis Isocitrate Lyase 1 by (2R,3S)-2-Hydroxy-3-(nitromethyl)succinic acid. Journal of the American Chemical Society 143 (42) (2021)
Linfeng Li, Bala C Chenna, Kai S Yang, Taylor R Cole, Zachary T Goodall, Miriam Giardini, Zahra Moghadamchargari, Elizabeth A Hernandez, Jana Gomez, Claudia M Calvet, Jean A Bernatchez, Drake M Mellott, Jiyun Zhu, Andrew Rademacher, Diane Thomas, Lauren R Blankenship, Aleksandra Drelich, Arthur D Laganowsky, Chien-Te K Tseng, Wenshe R Liu, A Joshua Wand, Jorge Cruz-Reyes, Jair Lage Siqueira-Neto, Thomas D Meek
Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases. Journal of medicinal chemistry 64 (15) (2021)
Bala C Chenna, Linfeng Li, Drake M Mellott, Xiang Zhai, Jair L Siqueira-Neto, Claudia Calvet Alvarez, Jean A Bernatchez, Emily Desormeaux, Elizabeth Alvarez Hernandez, Jana Gomez, James H McKerrow, Jorge Cruz-Reyes, Thomas D Meek
Peptidomimetic Vinyl Heterocyclic Inhibitors of Cruzain Effect Antitrypanosomal Activity. Journal of medicinal chemistry 63 (6) (2020)
Vern L Schramm, Thomas D Meek
Enhanced Antibiotic Discovery by PROSPECTing. Biochemistry 58 (33) (2019)
Yuying Ma, Linfeng Li, Shuai He, Chengyou Shang, Yang Sun, Ning Liu, Thomas D Meek, Yaxin Wang, Luqing Shang
Application of Dually Activated Michael Acceptor to the Rational Design of Reversible Covalent Inhibitor for Enterovirus 71 3C Protease. Journal of medicinal chemistry 62 (13) (2019)
Xiang Zhai, Thomas D Meek
Catalytic Mechanism of Cruzain from Trypanosoma cruzi As Determined from Solvent Kinetic Isotope Effects of Steady-State and Pre-Steady-State Kinetics. Biochemistry 57 (22) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Thomas D Meek