Vivian Hook

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 26

Top Topics

Mass Spectrometry

Trypanosoma Cruzi

Gene Expression

Top Venues

Molecular psychiatry

ACS chemical neuroscience

This page only lists publications with an associated author ORCID identifier.

Publications

Sonia Podvin, Jeffrey R Jones, Austin Kang, Ryan Goodman, Patrick Reed, Christopher B Lietz, Joshua Then, Kelly C Lee, Lisa T Eyler, Dilip V Jeste, Fred H Gage, Vivian Hook
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures. Molecular psychiatry (2024)
Sonia Podvin, Jeffrey R Jones, Austin Kang, Ryan Goodman, Patrick Reed, Christopher B Lietz, Joshua Then, Kelly C Lee, Lisa T Eyler, Dilip V Jeste, Fred H Gage, Vivian Hook
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures. Molecular psychiatry 29 (5) (2024)
Sonia Podvin, Jeffrey R Jones, Austin Kang, Ryan Goodman, Patrick Reed, Christopher B Lietz, Joshua Then, Kelly C Lee, Lisa T Eyler, Dilip V Jeste, Fred H Gage, Vivian Hook
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures. Molecular psychiatry (2024)
Jehad Almaliti, Momen Alhindy, Michael C Yoon, Vivian Hook, Tadeusz F Molinski, Anthony J O'Donoghue, William H Gerwick
Orthogonal Deprotection Strategy of Fmoc Provides Improved Synthesis of Sensitive Peptides: Application to Z-Arg-Lys-AOMK. ACS omega 9 (3) (2024)
Jehad Almaliti, Momen Alhindy, Michael C Yoon, Vivian Hook, Tadeusz F Molinski, Anthony J O'Donoghue, William H Gerwick
Orthogonal Deprotection Strategy of Fmoc Provides Improved Synthesis of Sensitive Peptides: Application to Z-Arg-Lys-AOMK. ACS omega 9 (3) (2024)
Sonia Podvin, Jeffrey R Jones, Austin Kang, Ryan Goodman, Patrick Reed, Christopher B Lietz, Joshua Then, Kelly C Lee, Lisa T Eyler, Dilip V Jeste, Fred H Gage, Vivian Hook
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures. Molecular psychiatry 29 (5) (2024)
Sonia Podvin, Jeffrey R Jones, Austin Kang, Ryan Goodman, Patrick Reed, Christopher B Lietz, Joshua Then, Kelly C Lee, Lisa T Eyler, Dilip V Jeste, Fred H Gage, Vivian Hook
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures. Molecular psychiatry (2024)
Jehad Almaliti, Momen Alhindy, Michael C Yoon, Vivian Hook, Tadeusz F Molinski, Anthony J O'Donoghue, William H Gerwick
Orthogonal Deprotection Strategy of Fmoc Provides Improved Synthesis of Sensitive Peptides: Application to Z-Arg-Lys-AOMK. ACS omega 9 (3) (2024)
Sonia Podvin, Jeffrey R Jones, Austin Kang, Ryan Goodman, Patrick Reed, Christopher B Lietz, Joshua Then, Kelly C Lee, Lisa T Eyler, Dilip V Jeste, Fred H Gage, Vivian Hook
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures. Molecular psychiatry 29 (5) (2024)
Michael C Yoon, Von Phan, Sonia Podvin, Charles Mosier, Anthony J O'Donoghue, Vivian Hook
Distinct Cleavage Properties of Cathepsin B Compared to Cysteine Cathepsins Enable the Design and Validation of a Specific Substrate for Cathepsin B over a Broad pH Range. Biochemistry (2023)
Michael C Yoon, Mitchell P Christy, Von V Phan, William H Gerwick, Gregory Hook, Anthony J O'Donoghue, Vivian Hook
Molecular Features of CA-074 pH-Dependent Inhibition of Cathepsin B. Biochemistry 61 (4) (2022)
Michael C Yoon, Janneca Ames, Charles Mosier, Zhenze Jiang, Sonia Podvin, Anthony J O'Donoghue, Vivian Hook
Distinct Dibasic Cleavage Specificities of Neuropeptide-Producing Cathepsin L and Cathepsin V Cysteine Proteases Compared to PC1/3 and PC2 Serine Proteases. ACS chemical neuroscience 13 (2) (2022)
Sonia Podvin, Zhenze Jiang, Ben Boyarko, Leigh-Ana Rossitto, Anthony J O'Donoghue, Robert A Rissman, Vivian Hook
Dysregulation of Neuropeptide and Tau Peptide Signatures in Human Alzheimer's Disease Brain. ACS chemical neuroscience 13 (13) (2022)
Michael C Yoon, Vivian Hook, Anthony J O'Donoghue
Cathepsin B Dipeptidyl Carboxypeptidase and Endopeptidase Activities Demonstrated across a Broad pH Range. Biochemistry 61 (17) (2022)
Von V Phan, Charles Mosier, Michael C Yoon, Evgenia Glukhov, Conor R Caffrey, Anthony J O'Donoghue, William H Gerwick, Vivian Hook
Discovery of pH-Selective Marine and Plant Natural Product Inhibitors of Cathepsin B Revealed by Screening at Acidic and Neutral pH Conditions. ACS omega 7 (29) (2022)
Drake M Mellott, Chien-Te Tseng, Aleksandra Drelich, Pavla Fajtová, Bala C Chenna, Demetrios H Kostomiris, Jason Hsu, Jiyun Zhu, Zane W Taylor, Klaudia I Kocurek, Vivian Tat, Ardala Katzfuss, Linfeng Li, Miriam A Giardini, Danielle Skinner, Ken Hirata, Michael C Yoon, Sungjun Beck, Aaron F Carlin, Alex E Clark, Laura Beretta, Daniel Maneval, Vivian Hook, Felix Frueh, Brett L Hurst, Hong Wang, Frank M Raushel, Anthony J O'Donoghue, Jair Lage de Siqueira-Neto, Thomas D Meek, James H McKerrow
A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells. ACS chemical biology 16 (4) (2021)
Sonia Podvin, Alexander Jones, Qing Liu, Brent Aulston, Charles Mosier, Janneca Ames, Charisse Winston, Christopher B Lietz, Zhenze Jiang, Anthony J O'Donoghue, Tsuneya Ikezu, Robert A Rissman, Shauna H Yuan, Vivian Hook
Mutant Presenilin 1 Dysregulates Exosomal Proteome Cargo Produced by Human-Induced Pluripotent Stem Cell Neurons. ACS omega 6 (20) (2021)
Zhenze Jiang, Christopher B Lietz, Sonia Podvin, Michael C Yoon, Thomas Toneff, Vivian Hook, Anthony J O'Donoghue
Differential Neuropeptidomes of Dense Core Secretory Vesicles (DCSV) Produced at Intravesicular and Extracellular pH Conditions by Proteolytic Processing. ACS chemical neuroscience 12 (13) (2021)
Michael C Yoon, Angelo Solania, Zhenze Jiang, Mitchell P Christy, Sonia Podvin, Charles Mosier, Christopher B Lietz, Gen Ito, William H Gerwick, Dennis W Wolan, Gregory Hook, Anthony J O'Donoghue, Vivian Hook
Selective Neutral pH Inhibitor of Cathepsin B Designed Based on Cleavage Preferences at Cytosolic and Lysosomal pH Conditions. ACS chemical biology 16 (9) (2021)
Betsaida Bibo-Verdugo, Steven C Wang, Jehad Almaliti, Anh P Ta, Zhenze Jiang, Derek A Wong, Christopher B Lietz, Brian M Suzuki, Nelly El-Sakkary, Vivian Hook, Guy S Salvesen, William H Gerwick, Conor R Caffrey, Anthony J O'Donoghue
The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni. ACS infectious diseases 5 (10) (2019)
Paul D Boudreau, Bailey W Miller, Laura-Isobel McCall, Jehad Almaliti, Raphael Reher, Ken Hirata, Thu Le, Jair L Siqueira-Neto, Vivian Hook, William H Gerwick
Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and Trypanosoma cruzi Cruzain. Journal of medicinal chemistry 62 (20) (2019)
Vivian Hook, Tobias Kind, Sonia Podvin, Mine Palazoglu, Carol Tran, Thomas Toneff, Stephanie Samra, Christopher Lietz, Oliver Fiehn
Metabolomics Analyses of 14 Classical Neurotransmitters by GC-TOF with LC-MS Illustrates Secretion of 9 Cell-Cell Signaling Molecules from Sympathoadrenal Chromaffin Cells in the Presence of Lithium. ACS chemical neuroscience 10 (3) (2019)
Christopher B Lietz, Thomas Toneff, Charles Mosier, Sonia Podvin, Anthony J O'Donoghue, Vivian Hook
Phosphopeptidomics Reveals Differential Phosphorylation States and Novel SxE Phosphosite Motifs of Neuropeptides in Dense Core Secretory Vesicles. Journal of the American Society for Mass Spectrometry 29 (5) (2018)
Amy Hsu, Sonia Podvin, Vivian Hook
Lysosomal Cathepsin Protease Gene Expression Profiles in the Human Brain During Normal Development. Journal of molecular neuroscience : MN 65 (4) (2018)
Sonia Podvin, Holly T Reardon, Katrina Yin, Charles Mosier, Vivian Hook
Multiple clinical features of Huntington's disease correlate with mutant HTT gene CAG repeat lengths and neurodegeneration. Journal of neurology 266 (3) (2018)
Vivian Hook, Christopher B Lietz, Sonia Podvin, Tomas Cajka, Oliver Fiehn
Diversity of Neuropeptide Cell-Cell Signaling Molecules Generated by Proteolytic Processing Revealed by Neuropeptidomics Mass Spectrometry. Journal of the American Society for Mass Spectrometry 29 (5) (2018)