James H McKerrow (James McKerrow)

Publication Activity (10 Years)

Years Active: 2018-2022
Publications (10 Years): 9

Top Topics

Respiratory Syndrome Coronavirus

Induced Pluripotent Stem Cells

Trypanosoma Cruzi

Top Venues

PLoS neglected tropical diseases

Journal of medicinal chemistry

ACS chemical biology

Journal of chemical information and modeling

This page only lists publications with an associated author ORCID identifier.

Publications

Jean A Bernatchez, Yun-Seo Kil, Elany Barbosa da Silva, Diane Thomas, Laura-Isobel McCall, Karen L Wendt, Julia M Souza, Jasmin Ackermann, James H McKerrow, Robert H Cichewicz, Jair Lage Siqueira-Neto
Identification of Leucinostatins from Ophiocordyceps sp. as Antiparasitic Agents against Trypanosoma cruzi . ACS omega 7 (9) (2022)
Thanigaimalai Pillaiyar, Philipp Flury, Nadine Krüger, Haixia Su, Laura Schäkel, Elany Barbosa da Silva, Olga Eppler, Thales Kronenberger, Tianqing Nie, Stephanie Luedtke, Cheila Rocha, Katharina Sylvester, Marvin R I Petry, James H McKerrow, Antti Poso, Stefan Pöhlmann, Michael Gütschow, Anthony J O'Donoghue, Yechun Xu, Christa Elisabeth Müller, Stefan A Laufer
Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure-Activity Relationships, Antiviral Activity, and X-ray Structure Determination. Journal of medicinal chemistry 65 (13) (2022)
Elany Barbosa da Silva, Vandna Sharma, Lilian Hernandez-Alvarez, Arthur H Tang, Alexander Stoye, Anthony J O'Donoghue, William H Gerwick, Richard J Payne, James H McKerrow, Larissa M Podust
Intramolecular Interactions Enhance the Potency of Gallinamide A Analogues against Trypanosoma cruzi . Journal of medicinal chemistry 65 (5) (2022)
Lucianna H Santos, Thales Kronenberger, Renata G Almeida, Elany Barbosa da Silva, Rafael E O Rocha, Joyce C Oliveira, Luiza V Barreto, Danielle Skinner, Pavla Fajtová, Miriam A Giardini, Brendon Woodworth, Conner Bardine, André L Lourenço, Charles S Craik, Antti Poso, Larissa M Podust, James H McKerrow, Jair Lage Siqueira-Neto, Anthony J O'Donoghue, Eufrânio N da Silva Júnior, Rafaela Salgado Ferreira
Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease M pro and Papain-like Protease PL pro of SARS-CoV-2. Journal of chemical information and modeling (2022)
Drake M Mellott, Chien-Te Tseng, Aleksandra Drelich, Pavla Fajtová, Bala C Chenna, Demetrios H Kostomiris, Jason Hsu, Jiyun Zhu, Zane W Taylor, Klaudia I Kocurek, Vivian Tat, Ardala Katzfuss, Linfeng Li, Miriam A Giardini, Danielle Skinner, Ken Hirata, Michael C Yoon, Sungjun Beck, Aaron F Carlin, Alex E Clark, Laura Beretta, Daniel Maneval, Vivian Hook, Felix Frueh, Brett L Hurst, Hong Wang, Frank M Raushel, Anthony J O'Donoghue, Jair Lage de Siqueira-Neto, Thomas D Meek, James H McKerrow
A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells. ACS chemical biology 16 (4) (2021)
Elany Barbosa da Silva, Débora A Rocha, Isadora S Fortes, Wenqian Yang, Ludovica Monti, Jair L Siqueira-Neto, Conor R Caffrey, James H McKerrow, Saulo Fernandes de Andrade, Rafaela Salgado Ferreira
Structure-Based Optimization of Quinazolines as Cruzain and TbrCATL Inhibitors. Journal of medicinal chemistry 64 (17) (2021)
Claudia Magalhães Calvet, Tatiana Araújo Silva, Diane Thomas, Brian Suzuki, Ken Hirata, Jair Lage Siqueira-Neto, James H McKerrow
Long term follow-up of Trypanosoma cruzi infection and Chagas disease manifestations in mice treated with benznidazole or posaconazole. PLoS neglected tropical diseases 14 (9) (2020)
James H McKerrow
The diverse roles of cysteine proteases in parasites and their suitability as drug targets. PLoS neglected tropical diseases 12 (8) (2018)
James H McKerrow
Update on drug development targeting parasite cysteine proteases. PLoS neglected tropical diseases 12 (8) (2018)