Jeffrey J Babon (Jeffery J Babon, Jeff J Babon)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 21

Top Topics

Intellectual Disability

Systemic Lupus Erythematosus

Disease Activity

Top Venues

Nature communications

The Journal of experimental medicine

Nature immunology

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Kaiseal T G Sarson-Lawrence, Joshua M Hardy, Josephine Iaria, Dina Stockwell, Kira Behrens, Tamanna Saiyed, Cyrus Tan, Leila Jebeli, Nichollas E Scott, Toby A Dite, Nicos A Nicola, Andrew P Leis, Jeffrey J Babon, Nadia J Kershaw
Cryo-EM structure of the extracellular domain of murine Thrombopoietin Receptor in complex with Thrombopoietin. Nature communications 15 (1) (2024)
Yaoyuan Zhang, Rhiannon Morris, Grant J Brown, Ayla May D Lorenzo, Xiangpeng Meng, Nadia J Kershaw, Pamudika Kiridena, Gaetan Burgio, Simon Gross, Jean Y Cappello, Qian Shen, Hao Wang, Cynthia Turnbull, Tom N Lea-Henry, Maurice Stanley, Zhijia Yu, Fiona D Ballard, Aaron Chuah, James C Lee, Ann-Maree Hatch, Anselm Enders, Seth L Masters, Alexander P Headley, Peter Trnka, Dominic Mallon, Jeffery T Fletcher, Giles D Walters, Mario Šestan, Marija Jelusic, Matthew C Cook, Vicki Athanasopoulos, David A Fulcher, Jeffrey J Babon, Carola G Vinuesa, Julia I Ellyard
Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity. The Journal of experimental medicine 221 (4) (2024)
Yaoyuan Zhang, Rhiannon Morris, Grant J Brown, Ayla May D Lorenzo, Xiangpeng Meng, Nadia J Kershaw, Pamudika Kiridena, Gaetan Burgio, Simon Gross, Jean Y Cappello, Qian Shen, Hao Wang, Cynthia Turnbull, Tom N Lea-Henry, Maurice Stanley, Zhijia Yu, Fiona D Ballard, Aaron Chuah, James C Lee, Ann-Maree Hatch, Anselm Enders, Seth L Masters, Alexander P Headley, Peter Trnka, Dominic Mallon, Jeffery T Fletcher, Giles D Walters, Mario Šestan, Marija Jelusic, Matthew C Cook, Vicki Athanasopoulos, David A Fulcher, Jeffrey J Babon, Carola G Vinuesa, Julia I Ellyard
Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity. The Journal of experimental medicine 221 (4) (2024)
Kaiseal T G Sarson-Lawrence, Joshua M Hardy, Josephine Iaria, Dina Stockwell, Kira Behrens, Tamanna Saiyed, Cyrus Tan, Leila Jebeli, Nichollas E Scott, Toby A Dite, Nicos A Nicola, Andrew P Leis, Jeffrey J Babon, Nadia J Kershaw
Cryo-EM structure of the extracellular domain of murine Thrombopoietin Receptor in complex with Thrombopoietin. Nature communications 15 (1) (2024)
Yaoyuan Zhang, Rhiannon Morris, Grant J Brown, Ayla May D Lorenzo, Xiangpeng Meng, Nadia J Kershaw, Pamudika Kiridena, Gaetan Burgio, Simon Gross, Jean Y Cappello, Qian Shen, Hao Wang, Cynthia Turnbull, Tom N Lea-Henry, Maurice Stanley, Zhijia Yu, Fiona D Ballard, Aaron Chuah, James C Lee, Ann-Maree Hatch, Anselm Enders, Seth L Masters, Alexander P Headley, Peter Trnka, Dominic Mallon, Jeffery T Fletcher, Giles D Walters, Mario Šestan, Marija Jelusic, Matthew C Cook, Vicki Athanasopoulos, David A Fulcher, Jeffrey J Babon, Carola G Vinuesa, Julia I Ellyard
Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity. The Journal of experimental medicine 221 (4) (2024)
Kaiseal T G Sarson-Lawrence, Joshua M Hardy, Josephine Iaria, Dina Stockwell, Kira Behrens, Tamanna Saiyed, Cyrus Tan, Leila Jebeli, Nichollas E Scott, Toby A Dite, Nicos A Nicola, Andrew P Leis, Jeffrey J Babon, Nadia J Kershaw
Cryo-EM structure of the extracellular domain of murine Thrombopoietin Receptor in complex with Thrombopoietin. Nature communications 15 (1) (2024)
Yaoyuan Zhang, Rhiannon Morris, Grant J Brown, Ayla May D Lorenzo, Xiangpeng Meng, Nadia J Kershaw, Pamudika Kiridena, Gaetan Burgio, Simon Gross, Jean Y Cappello, Qian Shen, Hao Wang, Cynthia Turnbull, Tom N Lea-Henry, Maurice Stanley, Zhijia Yu, Fiona D Ballard, Aaron Chuah, James C Lee, Ann-Maree Hatch, Anselm Enders, Seth L Masters, Alexander P Headley, Peter Trnka, Dominic Mallon, Jeffery T Fletcher, Giles D Walters, Mario Šestan, Marija Jelusic, Matthew C Cook, Vicki Athanasopoulos, David A Fulcher, Jeffrey J Babon, Carola G Vinuesa, Julia I Ellyard
Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity. The Journal of experimental medicine 221 (4) (2024)
Kaiseal T G Sarson-Lawrence, Joshua M Hardy, Josephine Iaria, Dina Stockwell, Kira Behrens, Tamanna Saiyed, Cyrus Tan, Leila Jebeli, Nichollas E Scott, Toby A Dite, Nicos A Nicola, Andrew P Leis, Jeffrey J Babon, Nadia J Kershaw
Cryo-EM structure of the extracellular domain of murine Thrombopoietin Receptor in complex with Thrombopoietin. Nature communications 15 (1) (2024)
Rhiannon Morris, Narelle Keating, Cyrus Tan, Hao Chen, Artem Laktyushin, Tamanna Saiyed, Nicholas P D Liau, Nicos A Nicola, Tony Tiganis, Nadia J Kershaw, Jeffrey J Babon
Structure guided studies of the interaction between PTP1B and JAK. Communications biology 6 (1) (2023)
Edmond M Linossi, Kunlun Li, Gianluca Veggiani, Cyrus Tan, Farhad Dehkhoda, Colin Hockings, Dale J Calleja, Narelle Keating, Rebecca Feltham, Andrew J Brooks, Shawn Shun-Cheng Li, Sachdev S Sidhu, Jeffrey J Babon, Nadia J Kershaw, Sandra E Nicholson
Author Correction: Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands. Nature communications 14 (1) (2023)
Shuwei Liang, Eric Tran, Xin Du, Jiajun Dong, Harrison Sudholz, Hao Chen, Zihan Qu, Nicholas D Huntington, Jeffrey J Babon, Nadia J Kershaw, Zhong-Yin Zhang, Jonathan B Baell, Florian Wiede, Tony Tiganis
A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity. Nature communications 14 (1) (2023)
Grant J Brown, Pablo F Cañete, Hao Wang, Arti Medhavy, Josiah Bones, Jonathan A Roco, Yuke He, Yuting Qin, Jean Cappello, Julia I Ellyard, Katharine Bassett, Qian Shen, Gaetan Burgio, Yaoyuan Zhang, Cynthia Turnbull, Xiangpeng Meng, Phil Wu, Vicky Cho, Lisa A Miosge, T Daniel Andrews, Matthew A Field, Denis Tvorogov, Angel F Lopez, Jeffrey J Babon, Cristina Aparicio López, África Gónzalez-Murillo, Daniel Clemente Garulo, Virginia M Pascual, Tess Levy, Eric James Mallack, Daniel G Calame, Timothy Lotze, James R. Lupski, Huihua Ding, Tomalika R Ullah, Giles D Walters, Mark E Koina, Matthew C Cook, Nan Shen, Carmen de Lucas Collantes, Ben Corry, Michael P Gantier, Vicki Athanasopoulos, Carola G Vinuesa
TLR7 gain-of-function genetic variation causes human lupus. Nature 605 (7909) (2022)
Shenggen Yao, David W Keizer, Jeffrey J Babon, Frances Separovic
NMR measurement of biomolecular translational and rotational motion for evaluating changes of protein oligomeric state in solution. European biophysics journal : EBJ 51 (3) (2022)
Edmond M Linossi, Kunlun Li, Gianluca Veggiani, Cyrus Tan, Farhad Dehkhoda, Colin Hockings, Dale J Calleja, Narelle Keating, Rebecca Feltham, Andrew J Brooks, Shawn Shun-Cheng Li, Sachdev S Sidhu, Jeffrey J Babon, Nadia J Kershaw, Sandra E Nicholson
Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands. Nature communications 12 (1) (2021)
Rhiannon Morris, Yaoyuan Zhang, Julia I Ellyard, Carola G Vinuesa, James G Murphy, Artem Laktyushin, Nadia J Kershaw, Jeffrey J Babon
Structural and functional analysis of target recognition by the lymphocyte adaptor protein LNK. Nature communications 12 (1) (2021)
Simon H Jiang, Vicki Athanasopoulos, Julia I Ellyard, Aaron Chuah, Jean Cappello, Amelia Cook, Savit B Prabhu, Jacob Cardenas, Jinghua Gu, Maurice Stanley, Jonathan A Roco, Ilenia Papa, Mehmet Yabas, Giles D Walters, Gaetan Burgio, Kathryn McKeon, James M Byers, Charlotte Burrin, Anselm Enders, Lisa A Miosge, Pablo F Canete, Marija Jelusic, Velibor Tasic, Adrian C Lungu, Stephen I Alexander, Arthur Richard Kitching, David A Fulcher, Nan Shen, Todor Arsov, Paul A Gatenby, Jeffrey J Babon, Dominic F Mallon, Carmen de Lucas Collantes, Eric A Stone, Philip Wu, Matthew A Field, Thomas D Andrews, Vicky Cho, Virginia M Pascual, Matthew C Cook, Carola G Vinuesa
Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus. Nature communications 10 (1) (2019)
Rhiannon Morris, Nadia J Kershaw, Jeffrey J Babon
The molecular details of cytokine signaling via the JAK/STAT pathway. Protein science : a publication of the Protein Society 27 (12) (2019)
Mary Speir, Cameron J Nowell, Alyce A Chen, Joanne A O'Donnell, Isaac S Shamie, Paul R Lakin, Akshay A D'Cruz, Roman Othmar Braun, Jeffrey J Babon, Rowena S Lewis, Meghan Bliss-Moreau, Inbar Shlomovitz, Shu Wang, Louise H Cengia, Anca I Stoica, Razq Hakem, Michelle A Kelliher, Lorraine A O'Reilly, Heather Patsiouras, Kate E Lawlor, Edie Weller, Nathan E Lewis, Andrew W Roberts, Mordechay Gerlic, Ben A Croker
Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation. Nature immunology 21 (1) (2019)
Denis Tvorogov, Daniel Thomas, Nicholas P D Liau, Mara Dottore, Emma F Barry, Maya Lathi, Winnie L Kan, Timothy R Hercus, Frank Stomski, Timothy P Hughes, Vinay Tergaonkar, Michael W Parker, David Morrall Ross, Ravindra Majeti, Jeffrey J Babon, Angel F Lopez
Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis. Science advances 4 (11) (2018)
Nicholas P D Liau, Artem Laktyushin, Isabelle S Lucet, James M Murphy, Shenggen Yao, Eden Whitlock, Kimberley Callaghan, Nicos A Nicola, Nadia J Kershaw, Jeffrey J Babon
The molecular basis of JAK/STAT inhibition by SOCS1. Nature communications 9 (1) (2018)
Rebecca B Delconte, Tatiana B Kolesnik, Laura F Dagley, Jai Rautela, Wei Shi, Eva Maria Putz, Kimberley Stannard, Jian-Guo Zhang, Charis Teh, Matt Firth, Takashi Ushiki, Christopher E Andoniou, Mariapia A Degli-Esposti, Phillip P Sharp, Caroline E Sanvitale, Giuseppe Infusini, Nicholas P D Liau, Edmond M Linossi, Christopher J Burns, Sebastian Carotta, Daniel H D Gray, Cyril Seillet, Dana S Hutchinson, Gabrielle T Belz, Andrew I Webb, Warren S Alexander, Shawn S Li, Alex N Bullock, Jeffrey J Babon, Mark J Smyth, Sandra E Nicholson, Nicholas D Huntington
CIS is a potent checkpoint in NK cell-mediated tumor immunity. Nature immunology 17 (7) (2016)
Monika Srivastava, Guowen Duan, Nadia J Kershaw, Vicki Athanasopoulos, Janet H C Yeo, Toyoyuki Ose, Desheng Hu, Simon H J Brown, Slobodan Jergic, Hardip R Patel, Alvin Pratama, Sashika Richards, Anil Verma, E Yvonne Jones, Vigo Heissmeyer, Thomas Preiss, Nicholas E Dixon, Mark M W Chong, Jeffrey J Babon, Carola G Vinuesa
Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis. Nature communications 6 (2015)