Walter Kolch (W Kolch)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 43

Top Topics

Transcription Factor

Mesenchymal Stem Cells

Top Venues

Journal of personalized medicine

The Biochemical journal

This page only lists publications with an associated author ORCID identifier.

Publications

Mary O'Reilly, Aleksandar Krstic, Luis F Iglesias-Martinez, Éanna J Ryan, Bruce Moran, Des Winter, Kieran Sheahan, Ray S McDermott, Walter Kolch
Genomic and Transcriptomic Analysis of a Patient with Early-Onset Colorectal Cancer and Therapy-Induced Focal Nodular Hyperplasia: A Case Report. Journal of personalized medicine 14 (6) (2024)
Oleksii S Rukhlenko, Hiroaki Imoto, Ayush Tambde, Amy McGillycuddy, Philipp Junk, Anna Tuliakova, Walter Kolch, Boris N Kholodenko
Cell State Transition Models Stratify Breast Cancer Cell Phenotypes and Reveal New Therapeutic Targets. Cancers 16 (13) (2024)
Giorgio Oliviero, Kieran Wynne, Darrell Andrews, John Crean, Walter Kolch, Gerard Cagney
Expression Proteomics and Histone Analysis Reveal Extensive Chromatin Network Changes and a Role for Histone Tail Trimming during Cellular Differentiation. Biomolecules 14 (7) (2024)
Oleksii S Rukhlenko, Hiroaki Imoto, Ayush Tambde, Amy McGillycuddy, Philipp Junk, Anna Tuliakova, Walter Kolch, Boris N Kholodenko
Cell State Transition Models Stratify Breast Cancer Cell Phenotypes and Reveal New Therapeutic Targets. Cancers 16 (13) (2024)
Giorgio Oliviero, Kieran Wynne, Darrell Andrews, John Crean, Walter Kolch, Gerard Cagney
Expression Proteomics and Histone Analysis Reveal Extensive Chromatin Network Changes and a Role for Histone Tail Trimming during Cellular Differentiation. Biomolecules 14 (7) (2024)
Giorgio Oliviero, Kieran Wynne, Darrell Andrews, John Crean, Walter Kolch, Gerard Cagney
Expression Proteomics and Histone Analysis Reveal Extensive Chromatin Network Changes and a Role for Histone Tail Trimming during Cellular Differentiation. Biomolecules 14 (7) (2024)
Mary O'Reilly, Aleksandar Krstic, Luis F Iglesias-Martinez, Éanna J Ryan, Bruce Moran, Des Winter, Kieran Sheahan, Ray S McDermott, Walter Kolch
Genomic and Transcriptomic Analysis of a Patient with Early-Onset Colorectal Cancer and Therapy-Induced Focal Nodular Hyperplasia: A Case Report. Journal of personalized medicine 14 (6) (2024)
Giorgio Oliviero, Kieran Wynne, Darrell Andrews, John Crean, Walter Kolch, Gerard Cagney
Expression Proteomics and Histone Analysis Reveal Extensive Chromatin Network Changes and a Role for Histone Tail Trimming during Cellular Differentiation. Biomolecules 14 (7) (2024)
Luis F Iglesias-Martinez, Nora Rauch, Kieran Wynne, Brendan McCann, Walter Kolch, Jens Rauch
Interactome dynamics of RAF1-BRAF kinase monomers and dimers. Scientific data 10 (1) (2023)
Walter Kolch, Dénes Berta, Edina Rosta
Dynamic regulation of RAS and RAS signaling. The Biochemical journal 480 (1) (2023)
Walter Kolch, Dénes Berta, Edina Rosta
Dynamic regulation of RAS and RAS signaling. The Biochemical journal 480 (1) (2023)
Donagh Egan, Martina Kreileder, Myriam Nabhan, Luis F Iglesias-Martinez, Simon J Dovedi, Viia Valge-Archer, Amit Grover, Robert W Wilkinson, Timothy Slidel, Claus Bendtsen, Ian P Barrett, Donal J Brennan, Walter Kolch, Vadim Zhernovkov
Small gene networks delineate immune cell states and characterize immunotherapy response in melanoma. Cancer immunology research (2023)
Zhi Liu, Aleksandar Krstic, Ashish J Neve, Cristina Casalou, Nora Rauch, Kieran Wynne, Hilary Cassidy, Amanda McCann, Emma Kavanagh, Brendan McCann, Alfonso Blanco, Jens Rauch, Walter Kolch
Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells. International journal of molecular sciences 24 (14) (2023)
Jordan F Hastings, Sharissa L Latham, Alvin Kamili, Madeleine S Wheatley, Jeremy Z R Han, Marie Wong, Monica Phimmachanh, Max Nobis, Chiara Pantarelli, Antonia L Cadell, Yolande E I O'Donnell, King Ho Leong, Sophie Lynn, Fan-Suo Geng, Lujing Cui, Sabrina Yan, Joanna Achinger-Kawecka, Clare Stirzaker, Murray D Norris, Michelle Haber, Toby N Trahair, Frank Speleman, Katleen De Preter, Mark J Cowley, Ozren Bogdanovic, Paul Timpson, Thomas R Cox, Walter Kolch, Jamie I Fletcher, Dirk Fey, David R Croucher
Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma. Science advances 9 (9) (2023)
Aoife Nolan, Cinzia Raso, Walter Kolch, Alexander von Kriegsheim, Kieran Wynne, David Matallanas
Proteomic Mapping of the Interactome of KRAS Mutants Identifies New Features of RAS Signalling Networks and the Mechanism of Action of Sotorasib. Cancers 15 (16) (2023)
Jordan F Hastings, Sharissa L Latham, Alvin Kamili, Madeleine S Wheatley, Jeremy Z R Han, Marie Wong, Monica Phimmachanh, Max Nobis, Chiara Pantarelli, Antonia L Cadell, Yolande E I O'Donnell, King Ho Leong, Sophie Lynn, Fan-Suo Geng, Lujing Cui, Sabrina Yan, Joanna Achinger-Kawecka, Clare Stirzaker, Murray D Norris, Michelle Haber, Toby N Trahair, Frank Speleman, Katleen De Preter, Mark J Cowley, Ozren Bogdanovic, Paul Timpson, Thomas R Cox, Walter Kolch, Jamie I Fletcher, Dirk Fey, David R Croucher
Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma. Science advances 9 (9) (2023)
Thomas Schwarzl, Andrea Keogh, Georgina Shaw, Aleksandar Krstic, Elizabeth Clayton, Desmond G Higgins, Walter Kolch, Frank Barry
Transcriptional profiling of early differentiation of primary human mesenchymal stem cells into chondrocytes. Scientific data 10 (1) (2023)
Walter Kolch, Dénes Berta, Edina Rosta
Dynamic regulation of RAS and RAS signaling. The Biochemical journal 480 (1) (2023)
Jordan F Hastings, Sharissa L Latham, Alvin Kamili, Madeleine S Wheatley, Jeremy Z R Han, Marie Wong, Monica Phimmachanh, Max Nobis, Chiara Pantarelli, Antonia L Cadell, Yolande E I O'Donnell, King Ho Leong, Sophie Lynn, Fan-Suo Geng, Lujing Cui, Sabrina Yan, Joanna Achinger-Kawecka, Clare Stirzaker, Murray D Norris, Michelle Haber, Toby N Trahair, Frank Speleman, Katleen De Preter, Mark J Cowley, Ozren Bogdanovic, Paul Timpson, Thomas R Cox, Walter Kolch, Jamie I Fletcher, Dirk Fey, David R Croucher
Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma. Science advances 9 (9) (2023)
Mary O'Reilly, Anna Linehan, Aleksandar Krstic, Walter Kolch, Kieran Sheahan, Des C Winter, Ray Mc Dermott
Oncotherapeutic Strategies in Early Onset Colorectal Cancer. Cancers 15 (2) (2023)
Mary O'Reilly, Anna Linehan, Aleksandar Krstic, Walter Kolch, Kieran Sheahan, Des C Winter, Ray Mc Dermott
Oncotherapeutic Strategies in Early Onset Colorectal Cancer. Cancers 15 (2) (2023)
Walter Kolch, Dénes Berta, Edina Rosta
Dynamic regulation of RAS and RAS signaling. The Biochemical journal 480 (1) (2023)
Annabelle Nwaokorie, Walter Kolch, Dirk Fey
A Systems Biology Approach to Understand the Racial Disparities in Colorectal Cancer. Cancer research communications (2023)
Nupur Mukherjee, Alacoque Browne, Laura Ivers, Tapesh Santra, Mattia Cremona, Bryan T Hennessy, Norma O'Donovan, John Crown, Walter Kolch, Dirk Fey, Alexander J Eustace
A Systems Biology Approach to Investigate Kinase Signal Transduction Networks That Are Involved in Triple Negative Breast Cancer Resistance to Cisplatin. Journal of personalized medicine 12 (8) (2022)
Darren Cowzer, Mohammed Zameer, Michael R Conroy, Walter Kolch, Austin G Duffy
Targeting KRAS in Pancreatic Cancer. Journal of personalized medicine 12 (11) (2022)
Oleksii S Rukhlenko, Melinda Halasz, Nora Rauch, Vadim Zhernovkov, Thomas Prince, Kieran Wynne, Stephanie Maher, Eugene Kashdan, Kenneth MacLeod, Neil O Carragher, Walter Kolch, Boris N Kholodenko
Control of cell state transitions. Nature 609 (7929) (2022)
Darren Cowzer, Mohammed Zameer, Michael R Conroy, Walter Kolch, Austin G Duffy
Targeting KRAS in Pancreatic Cancer. Journal of personalized medicine 12 (11) (2022)
David Romano, Lucía García-Gutiérrez, Nourhan K Aboud, David J Duffy, Keith T Flaherty, Dennie T Frederick, Walter Kolch, David Matallanas
Proteasomal down-regulation of the proapoptotic MST2 pathway contributes to BRAF inhibitor resistance in melanoma. Life science alliance 5 (10) (2022)
Honey Bokharaie, Walter Kolch, Aleksandar Krstic
Analysis of Alternative mRNA Splicing in Vemurafenib-Resistant Melanoma Cells. Biomolecules 12 (7) (2022)
Christina Kiel, David Matallanas, Walter Kolch
The Ins and Outs of RAS Effector Complexes. Biomolecules 11 (2) (2021)
Aoife A Nolan, Nourhan K Aboud, Walter Kolch, David Matallanas
Hidden Targets in RAF Signalling Pathways to Block Oncogenic RAS Signalling. Genes 12 (4) (2021)
Jeremy Z R Han, Jordan F Hastings, Monica Phimmachanh, Dirk Fey, Walter Kolch, David R Croucher
Personalized Medicine for Neuroblastoma: Moving from Static Genotypes to Dynamic Simulations of Drug Response. Journal of personalized medicine 11 (5) (2021)
Cathal Seoighe, Adrian P Bracken, Patrick Buckley, Peter Doran, Robert Green, Sandra Healy, David Kavanagh, Elaine Kenny, Mark Lawler, Maeve Lowery, Derek Morris, Darrin Morrissey, James J O'Byrne, Denis Shields, Owen Smith, Charles A Steward, Brian Sweeney, Walter Kolch
The future of genomics in Ireland - focus on genomics for health. HRB open research 3 (2020)
Lucía García-Gutiérrez, Stephanie McKenna, Walter Kolch, David Matallanas
RASSF1A Tumour Suppressor: Target the Network for Effective Cancer Therapy. Cancers 12 (1) (2020)
Susan A Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N Kholodenko, Luis F Iglesias-Martinez, Colm J Ryan, Ruth Pilkington, Patrizia Cammareri, Owen James Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J Lynn, Walter Kolch
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D. Nature communications 11 (1) (2020)
Shannon Lee, Jens Rauch, Walter Kolch
Targeting MAPK Signaling in Cancer: Mechanisms of Drug Resistance and Sensitivity. International journal of molecular sciences 21 (3) (2020)
Ana Herrero, Mariana Reis-Cardoso, Iñaki Jiménez-Gómez, Carolanne Doherty, Lorena Agudo-Ibañez, Adan Pinto-Fernandez, Fernando Calvo, Walter Kolch, Piero Crespo, David Matallanas
Characterisation of HRas local signal transduction networks using engineered site-specific exchange factors. Small GTPases 11 (5) (2018)
Jens Rauch, Walter Kolch
Spatial regulation of ARAF controls the MST2-Hippo pathway. Small GTPases 10 (4) (2017)
Branka Radic-Sarikas, Melinda Halasz, Kilian V M Huber, Georg E Winter, Kalliopi P Tsafou, Theodore Papamarkou, Søren Brunak, Walter Kolch, Giulio Superti-Furga
Lapatinib potentiates cytotoxicity of YM155 in neuroblastoma via inhibition of the ABCB1 efflux transporter. Scientific reports 7 (1) (2017)
Amandine Verlande, Michaela Krafčíková, David Potěšil, Lukáš Trantírek, Zbyněk Zdráhal, Moustafa Elkalaf, Jan Trnka, Karel Souček, Nora Rauch, Jens Rauch, Walter Kolch, Stjepan Uldrijan
Metabolic stress regulates ERK activity by controlling KSR-RAF heterodimerization. EMBO reports 19 (2) (2017)
Conor Daly, Lisa Shine, Theresa Heffernan, Sudhakar Deeti, Alison L Reynolds, John J O'Connor, Eugène T Dillon, David J Duffy, Walter Kolch, Gerard Cagney, Breandán N Kennedy
A Brain-Derived Neurotrophic Factor Mimetic Is Sufficient to Restore Cone Photoreceptor Visual Function in an Inherited Blindness Model. Scientific reports 7 (1) (2017)
J Rauch, D Vandamme, B Mack, B McCann, N Volinsky, A Blanco, O Gires, Walter Kolch
Differential localization of A-Raf regulates MST2-mediated apoptosis during epithelial differentiation. Cell death and differentiation 23 (8) (2016)
Philippe Bastiaens, Marc R Birtwistle, Nils Blüthgen, Frank J Bruggeman, Kwang-Hyun Cho, Carlo Cosentino, Alberto de la Fuente, Jan B Hoek, Anatoly Kiyatkin, Steffen Klamt, Walter Kolch, Stefan Legewie, Robert Müller, Takashi Naka, Tapesh Santra, Eduardo Sontag, Hans V Westerhoff, Boris N Kholodenko
Silence on the relevant literature and errors in implementation. Nature biotechnology 33 (4) (2015)