Xianming Deng

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 28

Top Venues

Nature communications

Journal of medicinal chemistry

The journal of physical chemistry. B

Science advances

Dana Farber Cancer Institute

Shanghai Institute of Organic Chemistry (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Dana Farber Cancer Institute Aug 07 2006 - Mar 29 2012

United States

Research Fellow :: Department of Cancer Biology

Harvard Medical School Aug 07 2006 - Mar 29 2012

United States

Research Fellow :: Department of Biological Chemistry and Molecular Pharmacology

Education History

Shanghai Institute of Organic Chemistry Sep 01 2001 - Jul 10 2006

China

PHD

Xiamen University Sep 01 1997 - Jul 01 2001

China

BSC :: Chemistry

Publications

Yixin Li, Yuezhou Wang, Xiaolan Lin, Shuqian Sun, Anan Wu, Yintong Ge, Menghui Yuan, Jianhua Wang, Xianming Deng, Yun Tian
Algicidal bacteria-derived membrane vesicles as shuttles mediating cross-kingdom interactions between bacteria and algae. Science advances 10 (32) (2024)
Yixin Li, Yuezhou Wang, Xiaolan Lin, Shuqian Sun, Anan Wu, Yintong Ge, Menghui Yuan, Jianhua Wang, Xianming Deng, Yun Tian
Algicidal bacteria-derived membrane vesicles as shuttles mediating cross-kingdom interactions between bacteria and algae. Science advances 10 (32) (2024)
Fangchen Hu, Yiqiu Wang, Juan Zeng, Xianming Deng, Fei Xia, Xin Xu
Unveiling the State Transition Mechanisms of Ras Proteins through Enhanced Sampling and QM/MM Simulations. The journal of physical chemistry. B 128 (6) (2024)
Ruixue Xu, Lirong Lin, Zhiwei Jiao, Rui Liang, Yazhen Guo, Yixin Zhang, Xiaoxu Shang, Yuezhou Wang, Xu Wang, Luming Yao, Shengfa Liu, Xianming Deng, Jing Yuan, Xin-Zhuan Su, Jian Li
Deaggregation of mutant Plasmodium yoelii de-ubiquitinase UBP1 alters MDR1 localization to confer multidrug resistance. Nature communications 15 (1) (2024)
Fangchen Hu, Yiqiu Wang, Juan Zeng, Xianming Deng, Fei Xia, Xin Xu
Unveiling the State Transition Mechanisms of Ras Proteins through Enhanced Sampling and QM/MM Simulations. The journal of physical chemistry. B 128 (6) (2024)
Fangchen Hu, Yiqiu Wang, Juan Zeng, Xianming Deng, Fei Xia, Xin Xu
Unveiling the State Transition Mechanisms of Ras Proteins through Enhanced Sampling and QM/MM Simulations. The journal of physical chemistry. B (2024)
Ruixue Xu, Lirong Lin, Zhiwei Jiao, Rui Liang, Yazhen Guo, Yixin Zhang, Xiaoxu Shang, Yuezhou Wang, Xu Wang, Luming Yao, Shengfa Liu, Xianming Deng, Jing Yuan, Xin-Zhuan Su, Jian Li
Deaggregation of mutant Plasmodium yoelii de-ubiquitinase UBP1 alters MDR1 localization to confer multidrug resistance. Nature communications 15 (1) (2024)
Mengqi Li, Yu Wang, Xiaoyan Wei, Wei-Feng Cai, Jianfeng Wu, Mingxia Zhu, Yongliang Wang, Yan-Hui Liu, Jinye Xiong, Qi Qu, Yan Chen, Xiao Tian, Luming Yao, Renxiang Xie, Xiaomin Li, Siwei Chen, Xi Huang, Cixiong Zhang, Changchuan Xie, Yaying Wu, Zheni Xu, Baoding Zhang, Bin Jiang, Zhi-Chao Wang, Qinxi Li, Gang Li, Shu-Yong Lin, Li Yu, Hai-Long Piao, Xianming Deng, Jiahuai Han, Chen-Song Zhang, Sheng-Cai Lin
AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine. Cell research (2024)
Ruixue Xu, Lirong Lin, Zhiwei Jiao, Rui Liang, Yazhen Guo, Yixin Zhang, Xiaoxu Shang, Yuezhou Wang, Xu Wang, Luming Yao, Shengfa Liu, Xianming Deng, Jing Yuan, Xin-Zhuan Su, Jian Li
Deaggregation of mutant Plasmodium yoelii de-ubiquitinase UBP1 alters MDR1 localization to confer multidrug resistance. Nature communications 15 (1) (2024)
Monica J Bohmer, Jinhua Wang, Eva S Istvan, Madeline R Luth, Jennifer E Collins, Edward L Huttlin, Lushun Wang, Nimisha Mittal, Mingfeng Hao, Nicholas P Kwiatkowski, Steven P Gygi, Ratna Chakrabarti, Xianming Deng, Daniel E Goldberg, Elizabeth A Winzeler, Nathanael S Gray, Debopam Chakrabarti
Human Polo-like Kinase Inhibitors as Antiplasmodials. ACS infectious diseases (2023)
Li Li, Yuezhou Wang, Naixin Chen, Xiaoyang Li, Hanpeng Li, Ling Jin, Yixin Ou, Xiang-Jian Kong, Shugeng Cao, Qingyan Xu, Xiaobing Wu, Jianyong Han, Xianming Deng
Exploring Diversity through Dimerization in Natural Products by a Rational Tandem Mass-Based Molecular Network Strategy. Organic letters (2023)
Monica J Bohmer, Jinhua Wang, Eva S Istvan, Madeline R Luth, Jennifer E Collins, Edward L Huttlin, Lushun Wang, Nimisha Mittal, Mingfeng Hao, Nicholas P Kwiatkowski, Steven P Gygi, Ratna Chakrabarti, Xianming Deng, Daniel E Goldberg, Elizabeth A Winzeler, Nathanael S Gray, Debopam Chakrabarti
Human Polo-like Kinase Inhibitors as Antiplasmodials. ACS infectious diseases (2023)
Chen-Song Zhang, Mengqi Li, Yu Wang, Xiaoyang Li, Yue Zong, Shating Long, Mingliang Zhang, Jin-Wei Feng, Xiaoyan Wei, Yan-Hui Liu, Baoding Zhang, Jianfeng Wu, Cixiong Zhang, Wenhua Lian, Teng Ma, Xiao Tian, Qi Qu, Yaxin Yu, Jinye Xiong, Dong-Tai Liu, Zhenhua Wu, Mingxia Zhu, Changchuan Xie, Yaying Wu, Zheni Xu, Chunyan Yang, Junjie Chen, Guohong Huang, Qingxia He, Xi Huang, Lei Zhang, Xiufeng Sun, Qingfeng Liu, Abdul Ghafoor, Fu Gui, Kaili Zheng, Wen Wang, Zhi-Chao Wang, Yong Yu, Qingliang Zhao, Shu-Yong Lin, Zhi-Xin Wang, Hai-Long Piao, Xianming Deng, Sheng-Cai Lin
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK. Nature metabolism 4 (10) (2022)
Qi-Tao Chen, Zhi-Yuan Zhang, Qiao-Ling Huang, Hang-Zi Chen, Wen-Bin Hong, Tianwei Lin, Wen-Xiu Zhao, Xiao-Min Wang, Cui-Yu Ju, Liu-Zheng Wu, Ya-Ying Huang, Pei-Pei Hou, Wei-Jia Wang, Dawang Zhou, Xianming Deng, Qiao Wu
HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma. Nature metabolism 4 (10) (2022)
Liying Feng, Kai Chen, Wei Huang, Yuelong Jiang, Xihuan Sun, Yong Zhou, Li Li, Yin Li, Xianming Deng, Bing Xu
Pharmacological targeting PIKfyve and tubulin as an effective treatment strategy for double-hit lymphoma. Cell death discovery 8 (1) (2022)
Teng Ma, Xiao Tian, Baoding Zhang, Mengqi Li, Yu Wang, Chunyan Yang, Jianfeng Wu, Xiaoyan Wei, Qi Qu, Yaxin Yu, Shating Long, Jin-Wei Feng, Chun Li, Cixiong Zhang, Changchuan Xie, Yaying Wu, Zheni Xu, Junjie Chen, Yong Yu, Xi Huang, Ying He, Luming Yao, Lei Zhang, Mingxia Zhu, Wen Wang, Zhi-Chao Wang, Mingliang Zhang, Yuqian Bao, Weiping Jia, Shu-Yong Lin, Zhiyun Ye, Hai-Long Piao, Xianming Deng, Chen-Song Zhang, Sheng-Cai Lin
Low-dose metformin targets the lysosomal AMPK pathway through PEN2. Nature 603 (7899) (2022)
Jingyi Su, Jing Zheng, Wei Huang, Yali Zhang, Cairui Lv, Baoding Zhang, Lina Jiang, Tong Cheng, Quan Yuan, Ning-Shao Xia, Jianming Zhang, Li Li, Li Li, Xianming Deng
PIKfyve inhibitors against SARS-CoV-2 and its variants including Omicron. Signal transduction and targeted therapy 7 (1) (2022)
Huiling Guo, Juan Wang, Su Ren, Lang-Fan Zheng, Yi-Xuan Zhuang, Dong-Lin Li, Hui-Hui Sun, Li-Ying Liu, Changchuan Xie, Ya-Ying Wu, Hong-Rui Wang, Xianming Deng, Peng Li, Tong-Jin Zhao
Targeting EGFR-dependent tumors by disrupting an ARF6-mediated sorting system. Nature communications 13 (1) (2022)
Yue Lu, Zhenzhen Fan, Su-Jie Zhu, Xiaoxing Huang, Zhongji Zhuang, Yunzhan Li, Zhou Deng, Lei Gao, Xuehui Hong, Ting Zhang, Li Li, Xihuan Sun, Wei Huang, Jingfang Zhang, Yan Liu, Baoding Zhang, Jie Jiang, Fu Gui, Zheng Wang, Qiyuan Li, Siyang Song, Xin Huang, Qiao Wu, Lanfen Chen, Dawang Zhou, Jianming Zhang, Cai-Hong Yun, Liang Chen, Xianming Deng
A new ALK inhibitor overcomes resistance to first- and second-generation inhibitors in NSCLC. EMBO molecular medicine (2021)
Lei Zhang, Yuezhou Wang, Wei Huang, Yanling Wei, Zile Jiang, Lulin Kong, An-An Wu, Zhiyu Hu, Huiying Huang, Qingyan Xu, Li Li, Xianming Deng
Biosynthesis and Chemical Diversification of Verucopeptin Leads to Structural and Functional Versatility. Organic letters 22 (11) (2020)
Wenjuan Li, Hengxiao Ni, Shaofeng Wu, Shang Han, Chang'an Chen, Li Li, Yunzhan Li, Fu Gui, Jiahuai Han, Xianming Deng
Targeting RIPK3 oligomerization blocks necroptosis without inducing apoptosis. FEBS letters 594 (14) (2020)
Fleur M Ferguson, Yan Liu, Wayne Harshbarger, Ling Huang, Jinhua Wang, Xianming Deng, Stephen J Capuzzi, Eugene N Muratov, Alexander Trospsha, Senthil Muthuswamy, Kenneth D Westover, Nathanael S Gray
Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one Scaffold. Journal of medicinal chemistry 63 (14) (2020)
Fleur M Ferguson, Yan Liu, Wayne Harshbarger, Ling Huang, Jinhua Wang, Xianming Deng, Stephen J Capuzzi, Eugene N Muratov, Alexander Trospsha, Senthil Muthuswamy, Kenneth D Westover, Nathanael S Gray
Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one Scaffold". Journal of medicinal chemistry 63 (17) (2020)
Peng-Bo Yang, Pei-Pei Hou, Fu-Yuan Liu, Wen-Bin Hong, Hang-Zi Chen, Xiao-Yu Sun, Peng Li, Yi Zhang, Cui-Yu Ju, Li-Juan Luo, Sheng-Fu Wu, Jia-Xin Zhou, Zhi-Jing Wang, Jian-Ping He, Li Li, Tong-Jin Zhao, Xianming Deng, Tianwei Lin, Qiao Wu
Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression. Proceedings of the National Academy of Sciences of the United States of America 117 (44) (2020)
Fu Gui, Jie Jiang, Zhixiang He, Li Li, Yunzhan Li, Zhou Deng, Yue Lu, Xinrui Wu, Guyue Chen, Jingyi Su, Siyang Song, Yue-Ming Zhang, Cai-Hong Yun, Xin Huang, Ellen Weisberg, Jianming Zhang, Xianming Deng
A non-covalent inhibitor XMU-MP-3 overrides ibrutinib-resistant BtkC481S mutation in B-cell malignancies. British journal of pharmacology 176 (23) (2019)
Jinhua Wang, Tatiana Erazo, Fleur M Ferguson, Dennis L Buckley, Nestor Gomez, Pau Muñoz-Guardiola, Nora Diéguez-Martínez, Xianming Deng, Mingfeng Hao, Walter Massefski, Oleg Fedorov, Nana Kwaku Offei-Addo, Paul M C Park, Lingling Dai, Amy DiBona, Kelly Becht, Nam Doo Kim, Michael R McKeown, Justin M Roberts, Jinwei Zhang, Taebo Sim, Dario R Alessi, James E Bradner, Jose M Lizcano, Stephen C Blacklow, Jun Qi, Xiang Xu, Nathanael S Gray
Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains. ACS chemical biology 13 (9) (2018)
Wei Huang, Xihuan Sun, Yunzhan Li, Zhixiang He, Li Li, Zhou Deng, Xiaoxing Huang, Shang Han, Ting Zhang, Jiaji Zhong, Zheng Wang, Qingyan Xu, Jianming Zhang, Xianming Deng
Discovery and Identification of Small Molecules as Methuosis Inducers with in Vivo Antitumor Activities. Journal of medicinal chemistry 61 (12) (2018)
Anna Czarna, Jinhua Wang, Diana Zelencova, Yao Liu, Xianming Deng, Hwan Geun Choi, Tinghu Zhang, Wenjun Zhou, Jae Won Chang, Hanne Kildalsen, Ole Morten Seternes, Nathanael S Gray, Richard Alan Engh, Ulli Rothweiler
Novel Scaffolds for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase (DYRK1A) Inhibitors. Journal of medicinal chemistry 61 (17) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Xianming Deng