Kenneth D Westover (Kenneth Westover)

Loop profile ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 24

Top Venues

Journal of medicinal chemistry

Nature chemical biology

Cancer research

Scientific reports

The University of Texas Southwestern Medical Center

Stanford University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The University of Texas Southwestern Medical Center Jul 01 2012

United States

Associate Professor :: Radiation Oncology

Education History

Stanford University Jan 09 1999 - Mar 31 2005

United States

PHD :: Biophysics

Brigham Young University Jun 01 1995

United States

BSC

Publications

Kenneth D Westover
Another KRAS variant trapped. Nature chemical biology 20 (9) (2024)
Kenneth D Westover
Another KRAS variant trapped. Nature chemical biology (2024)
Kenneth D Westover
Another KRAS variant trapped. Nature chemical biology 20 (9) (2024)
Wen Chao Lu, Yao Liu, Yang Gao, Qixiang Geng, Deepak Gurbani, Lianbo Li, Scott B Ficarro, Cynthia J Meyer, Dhiraj Sinha, Inchul You, Jason Tse, Zhixiang He, Wenzhi Ji, Jianwei Che, Audrey Y Kim, Tengteng Yu, Kenneth Wen, Kenneth C Anderson, Jarrod A Marto, Kenneth D Westover, Tinghu Zhang, Nathanael S Gray
Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. Journal of medicinal chemistry (2023)
Wen Chao Lu, Yao Liu, Yang Gao, Qixiang Geng, Deepak Gurbani, Lianbo Li, Scott B Ficarro, Cynthia J Meyer, Dhiraj Sinha, Inchul You, Jason Tse, Zhixiang He, Wenzhi Ji, Jianwei Che, Audrey Y Kim, Tengteng Yu, Kenneth Wen, Kenneth C Anderson, Jarrod A Marto, Kenneth D Westover, Tinghu Zhang, Nathanael S Gray
Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. Journal of medicinal chemistry 66 (5) (2023)
Wen Chao Lu, Yao Liu, Yang Gao, Qixiang Geng, Deepak Gurbani, Lianbo Li, Scott B Ficarro, Cynthia J Meyer, Dhiraj Sinha, Inchul You, Jason Tse, Zhixiang He, Wenzhi Ji, Jianwei Che, Audrey Y Kim, Tengteng Yu, Kenneth Wen, Kenneth C Anderson, Jarrod A Marto, Kenneth D Westover, Tinghu Zhang, Nathanael S Gray
Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. Journal of medicinal chemistry 66 (5) (2023)
Wen Chao Lu, Yao Liu, Yang Gao, Qixiang Geng, Deepak Gurbani, Lianbo Li, Scott B Ficarro, Cynthia J Meyer, Dhiraj Sinha, Inchul You, Jason Tse, Zhixiang He, Wenzhi Ji, Jianwei Che, Audrey Y Kim, Tengteng Yu, Kenneth Wen, Kenneth C Anderson, Jarrod A Marto, Kenneth D Westover, Tinghu Zhang, Nathanael S Gray
Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. Journal of medicinal chemistry (2023)
Wen Chao Lu, Yao Liu, Yang Gao, Qixiang Geng, Deepak Gurbani, Lianbo Li, Scott B Ficarro, Cynthia J Meyer, Dhiraj Sinha, Inchul You, Jason Tse, Zhixiang He, Wenzhi Ji, Jianwei Che, Audrey Y Kim, Tengteng Yu, Kenneth Wen, Kenneth C Anderson, Jarrod A Marto, Kenneth D Westover, Tinghu Zhang, Nathanael S Gray
Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. Journal of medicinal chemistry 66 (5) (2023)
Nora-Guadalupe P Ramirez, Jeon Lee, Yue Zheng, Lianbo Li, Bryce Dennis, Didi Chen, Ashwini Challa, Vicente Planelles, Kenneth D Westover, Neal M Alto, Iván D'Orso
ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-ERK-AP-1 T cell signaling-transcriptional axis. Nature communications 13 (1) (2022)
Kari Kopra, Salla Valtonen, Randa Mahran, Jonas N Kapp, Nazia Hassan, William K Gillette, Bryce Dennis, Lianbo Li, Kenneth D Westover, Andreas Plückthun, Harri Härmä
Thermal Shift Assay for Small GTPase Stability Screening: Evaluation and Suitability. International journal of molecular sciences 23 (13) (2022)
Paul Yenerall, Rahul K Kollipara, Kimberley Avila, Michael Peyton, Christopher A Eide, Daniel Bottomly, Shannon K McWeeney, Yan Liu, Kenneth D Westover, Brian J Druker, John D Minna, Ralf Kittler
Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations. Cancer research 81 (18) (2021)
Venkatesh P Mysore, Zhi-Wei Zhou, Chiara Ambrogio, Lianbo Li, Jonas N Kapp, Chunya Lu, Qi Wang, Maxwell R Tucker, Jeffrey J Okoro, Gabriela Nagy-Davidescu, Xiao-Chen Bai, Andreas Plückthun, Pasi A Janne, Kenneth D Westover, Yibing Shan, David E Shaw
A structural model of a Ras-Raf signalosome. Nature structural & molecular biology 28 (10) (2021)
Sudershan R Gondi, Althaf Shaik, Kenneth D Westover
Acid-Catalyzed Synthesis of Isatoic Anhydride-8-Secondary Amides Enables IASA Transformations for Medicinal Chemistry. The Journal of organic chemistry 87 (1) (2021)
Asim K Bera, Jia Lu, Chunya Lu, Lianbo Li, Sudershan Gondi, Wei Yan, Andrew Nelson, Goujun Zhang, Kenneth D Westover
GTP hydrolysis is modulated by Arg34 in the RASopathy-associated KRASP34R. Birth defects research 112 (10) (2020)
Fleur M Ferguson, Behnam Nabet, Srivatsan Raghavan, Yan Liu, Alan L Leggett, Miljan Kuljanin, Radha L Kalekar, Annan Yang, Shuning He, Jinhua Wang, Raymond W S Ng, Rita Sulahian, Lianbo Li, Emily J Poulin, Ling Huang, Jost Koren, Nora Dieguez-Martinez, Sergio Espinosa, Zhiyang Zeng, Cesear R Corona, James D Vasta, Ryoma Ohi, Taebo Sim, Nam Doo Kim, Wayne Harshbarger, Jose Miguel Lizcano, Matthew B Robers, Senthil Muthaswamy, Charles Y Lin, A Thomas Look, Kevin M Haigis, Joseph D Mancias, Brian M Wolpin, Andrew J Aguirre, William C Hahn, Kenneth D Westover, Nathanael S Gray
Discovery of a selective inhibitor of doublecortin like kinase 1. Nature chemical biology 16 (6) (2020)
Guangyan Du, Suman Rao, Deepak Gurbani, Nathaniel J Henning, Jie Jiang, Jianwei Che, Annan Yang, Scott B Ficarro, Jarrod A Marto, Andrew J Aguirre, Peter K Sorger, Kenneth D Westover, Tinghu Zhang, Nathanael S Gray
Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine. Journal of medicinal chemistry 63 (4) (2020)
Fleur M Ferguson, Yan Liu, Wayne Harshbarger, Ling Huang, Jinhua Wang, Xianming Deng, Stephen J Capuzzi, Eugene N Muratov, Alexander Trospsha, Senthil Muthuswamy, Kenneth D Westover, Nathanael S Gray
Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one Scaffold. Journal of medicinal chemistry 63 (14) (2020)
Fleur M Ferguson, Yan Liu, Wayne Harshbarger, Ling Huang, Jinhua Wang, Xianming Deng, Stephen J Capuzzi, Eugene N Muratov, Alexander Trospsha, Senthil Muthuswamy, Kenneth D Westover, Nathanael S Gray
Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one Scaffold". Journal of medicinal chemistry 63 (17) (2020)
Zhi-Wei Zhou, Chiara Ambrogio, Asim K Bera, Lianbo Li, Jieun Son, Sudershan Gondi, Emily Campbell, Hua Jin, Jeffrey J Okoro, Cheng-Xiong Xu, Pasi A Janne, Kenneth D Westover
KRASQ61H Preferentially Signals through MAPK in a RAF Dimer-Dependent Manner in Non-Small Cell Lung Cancer. Cancer research 80 (17) (2020)
Asim K Bera, Jia Lu, Thomas E Wales, Sudershan Gondi, Deepak Gurbani, Andrew Nelson, John R Engen, Kenneth D Westover
Structural basis of the atypical activation mechanism of KRASV14I. The Journal of biological chemistry 294 (38) (2019)
Sudershan R Gondi, Asim K Bera, Kenneth D Westover
Publisher Correction: Green Synthesis of Substituted Anilines and Quinazolines from Isatoic Anhydride-8-amide. Scientific reports 9 (1) (2019)
Sudershan R Gondi, Asim K Bera, Kenneth D Westover
Green Synthesis of Substituted Anilines and Quinazolines from Isatoic Anhydride-8-amide. Scientific reports 9 (1) (2019)
Emily J Poulin, Asim K Bera, Jia Lu, Yi-Jang Lin, Samantha Dale Strasser, Joao A Paulo, Tannie Q Huang, Carolina Morales, Wei Yan, Joshua H Cook, Jonathan A Nowak, Douglas K Brubaker, Brian A Joughin, Christian W Johnson, Rebecca A DeStefanis, Phaedra C Ghazi, Sudershan Gondi, Thomas E Wales, Roxana E Iacob, Lana Bogdanova, Jessica J Gierut, Yina Li, John R Engen, Pedro A Perez-Mancera, Benjamin S Braun, Steven P Gygi, Douglas A Lauffenburger, Kenneth D Westover, Kevin M Haigis
Tissue-Specific Oncogenic Activity of KRASA146T. Cancer discovery 9 (6) (2019)
Jia Lu, Asim K Bera, Sudershan Gondi, Kenneth D Westover
KRAS Switch Mutants D33E and A59G Crystallize in the State 1 Conformation. Biochemistry 57 (3) (2017)

Kenneth D Westover.css-eqlu8i{font-size:small;padding-left:4px;} (Kenneth Westover)

Publication Activity (10 Years)

Top Topics

Top Venues

Kenneth D Westover (Kenneth Westover)