Xin-Yuan Guan (Xinyuan Guan)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 62

Top Topics

Squamous Cell Carcinoma

Signaling Pathway

Top Venues

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Nature communications

Signal transduction and targeted therapy

This page only lists publications with an associated author ORCID identifier.

Publications

Dan Liao, Li Zhong, Junqiang Yin, Cuiling Zeng, Xin Wang, Xingchuan Huang, Gina Jinna Chen, Hong Zhang, Ruhua Zhang, Xin-Yuan Guan, Xintao Shuai, Jianhua Sui, Song Gao, Wuguo Deng, Yi-Xin Zeng, Jing-Nan Shen, Jian Chen, Tie-Bang Kang
Author Correction: Chromosomal translocation-derived aberrant Rab22a drives metastasis of osteosarcoma. Nature cell biology (2024)
Jiao Huang, Wai Ying Tsang, Xiao-Na Fang, Yu Zhang, Jie Luo, Lan-Qi Gong, Bai-Feng Zhang, Ching Ngar Wong, Zhi-Hong Li, Bei-Lei Liu, Jin-Lin Huang, Yu-Ma Yang, Shan Liu, Liu-Xian Ban, Yiu Hong Chan, Xin-Yuan Guan
FASN Inhibition Decreases MHC-I Degradation and Synergizes with PD-L1 Checkpoint Blockade in Hepatocellular Carcinoma. Cancer research 84 (6) (2024)
Bei-Lei Liu, Hongyu Zhou, Licheng Tan, Kin To Hugo Siu, Xin-Yuan Guan
Exploring treatment options in cancer: Tumor treatment strategies. Signal transduction and targeted therapy 9 (1) (2024)
Ching Ngar Wong, Yu Zhang, Beibei Ru, Songna Wang, Hongyu Zhou, Jiarun Lin, Yingchen Lyu, Yanru Qin, Peng Jiang, Victor Ho-Fun Lee, Xin-Yuan Guan
Identification and Characterization of Metastasis-Initiating Cells in ESCC in a Multi-Timepoint Pulmonary Metastasis Mouse Model. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (30) (2024)
Jiao Huang, Wai Ying Tsang, Xiao-Na Fang, Yu Zhang, Jie Luo, Lan-Qi Gong, Bai-Feng Zhang, Ching Ngar Wong, Zhi-Hong Li, Bei-Lei Liu, Jin-Lin Huang, Yu-Ma Yang, Shan Liu, Liu-Xian Ban, Yiu Hong Chan, Xin-Yuan Guan
FASN Inhibition Decreases MHC-I Degradation and Synergizes with PD-L1 Checkpoint Blockade in Hepatocellular Carcinoma. Cancer research 84 (6) (2024)
Bei-Lei Liu, Hongyu Zhou, Licheng Tan, Kin To Hugo Siu, Xin-Yuan Guan
Exploring treatment options in cancer: Tumor treatment strategies. Signal transduction and targeted therapy 9 (1) (2024)
Ching Ngar Wong, Yu Zhang, Beibei Ru, Songna Wang, Hongyu Zhou, Jiarun Lin, Yingchen Lyu, Yanru Qin, Peng Jiang, Victor Ho-Fun Lee, Xin-Yuan Guan
Identification and Characterization of Metastasis-Initiating Cells in ESCC in a Multi-Timepoint Pulmonary Metastasis Mouse Model. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2024)
Bei-Lei Liu, Hongyu Zhou, Licheng Tan, Kin To Hugo Siu, Xin-Yuan Guan
Exploring treatment options in cancer: Tumor treatment strategies. Signal transduction and targeted therapy 9 (1) (2024)
Ching Ngar Wong, Yu Zhang, Beibei Ru, Songna Wang, Hongyu Zhou, Jiarun Lin, Yingchen Lyu, Yanru Qin, Peng Jiang, Victor Ho-Fun Lee, Xin-Yuan Guan
Identification and Characterization of Metastasis-Initiating Cells in ESCC in a Multi-Timepoint Pulmonary Metastasis Mouse Model. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (30) (2024)
Xiang-Peng Tan, Yan He, Jing Yang, Xian Wei, You-Long Fan, Guo-Geng Zhang, Yi-Dong Zhu, Zheng-Qiu Li, Hua-Xin Liao, Da-Jiang Qin, Xin-Yuan Guan, Bin Li
Blockade of NMT1 enzymatic activity inhibits N-myristoylation of VILIP3 protein and suppresses liver cancer progression. Signal transduction and targeted therapy 8 (1) (2023)
Fu Peng, Hailin Tang, Peng Liu, Jiangang Shen, Xin-Yuan Guan, Xiaofang Xie, Jihai Gao, Liang Xiong, Lei Jia, Jianping Chen, Cheng Peng
Author Correction: Isoliquiritigenin modulates miR-374a/PTEN/Akt axis to suppress breast cancer tumorigenesis and metastasis. Scientific reports 13 (1) (2023)
Yongxu Jia, Bai-Feng Zhang, Chunyang Zhang, Dora Lai-Wan Kwong, Zhiwei Chang, Shanshan Li, Zehua Wang, Huiqiong Han, Jing Li, Yali Zhong, Xin Sui, Li Fu, Xin-Yuan Guan, Yanru Qin
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Esophageal Squamous Cell Carcinoma. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (7) (2023)
Xiang-Peng Tan, Yan He, Jing Yang, Xian Wei, You-Long Fan, Guo-Geng Zhang, Yi-Dong Zhu, Zheng-Qiu Li, Hua-Xin Liao, Da-Jiang Qin, Xin-Yuan Guan, Bin Li
Blockade of NMT1 enzymatic activity inhibits N-myristoylation of VILIP3 protein and suppresses liver cancer progression. Signal transduction and targeted therapy 8 (1) (2023)
Qian Yan, Xiaona Fang, Xiaoxia Liu, Sai Guo, Siqi Chen, Min Luo, Ping Lan, Xin-Yuan Guan
Loss of ESRP2 Activates TAK1-MAPK Signaling through the Fetal RNA-Splicing Program to Promote Hepatocellular Carcinoma Progression. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2023)
Xia Wang, Hongyang Huang, Karen Man-Fong Sze, Jin Wang, Lu Tian, Jingyi Lu, Yu-Man Tsui, Hoi Tang Ma, Eva Lee, Ao Chen, Joyce Lee, Ying Wang, Judy Wai Ping Yam, Tan-To Cheung, Xin-Yuan Guan, Irene Oi Lin Ng
S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos. Gut (2023)
Ki-Fong Man, Lei Zhou, Huajian Yu, Ka-Hei Lam, Wei Cheng, Xin Yu, Terence Kin-Wah Lee, Jing-Ping Yun, Xin-Yuan Guan, Ming Liu, Stephianie Ma
SPINK1-induced tumor plasticity provides a therapeutic window for chemotherapy in hepatocellular carcinoma. Nature communications 14 (1) (2023)
Yongxu Jia, Bai-Feng Zhang, Chunyang Zhang, Dora Lai-Wan Kwong, Zhiwei Chang, Shanshan Li, Zehua Wang, Huiqiong Han, Jing Li, Yali Zhong, Xin Sui, Li Fu, Xin-Yuan Guan, Yanru Qin
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Esophageal Squamous Cell Carcinoma. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (7) (2023)
Lily Liang, Xu Zhang, Xiaodong Su, Tingting Zeng, Daqin Suo, Jing-Ping Yun, Xin Wang, Xin-Yuan Guan, Yan Li
Fibroblasts in metastatic lymph nodes confer cisplatin resistance to ESCC tumor cells via PI16. Oncogenesis 12 (1) (2023)
Xiang-Peng Tan, Yan He, Jing Yang, Xian Wei, You-Long Fan, Guo-Geng Zhang, Yi-Dong Zhu, Zheng-Qiu Li, Hua-Xin Liao, Da-Jiang Qin, Xin-Yuan Guan, Bin Li
Blockade of NMT1 enzymatic activity inhibits N-myristoylation of VILIP3 protein and suppresses liver cancer progression. Signal transduction and targeted therapy 8 (1) (2023)
Yongxu Jia, Bai-Feng Zhang, Chunyang Zhang, Dora Lai-Wan Kwong, Zhiwei Chang, Shanshan Li, Zehua Wang, Huiqiong Han, Jing Li, Yali Zhong, Xin Sui, Li Fu, Xin-Yuan Guan, Yanru Qin
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Esophageal Squamous Cell Carcinoma. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (7) (2023)
Yongxu Jia, Bai-Feng Zhang, Chunyang Zhang, Dora Lai-Wan Kwong, Zhiwei Chang, Shanshan Li, Zehua Wang, Huiqiong Han, Jing Li, Yali Zhong, Xin Sui, Li Fu, Xin-Yuan Guan, Yanru Qin
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Esophageal Squamous Cell Carcinoma. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2023)
Xiang-Peng Tan, Yan He, Jing Yang, Xian Wei, You-Long Fan, Guo-Geng Zhang, Yi-Dong Zhu, Zheng-Qiu Li, Hua-Xin Liao, Da-Jiang Qin, Xin-Yuan Guan, Bin Li
Blockade of NMT1 enzymatic activity inhibits N-myristoylation of VILIP3 protein and suppresses liver cancer progression. Signal transduction and targeted therapy 8 (1) (2023)
Bei-Lei Liu, Bai-Feng Zhang, Jiali Qi, Hongyu Zhou, Licheng Tan, Jinlin Huang, Jiao Huang, Xiaona Fang, Lanqi Gong, Jie Luo, Shan Liu, Li Fu, Fei Ling, Stephianie Ma, Dora Lai-Wan Kwong, Xin Wang, Xin-Yuan Guan
Targeting MFGE8 secreted by cancer-associated fibroblasts blocks angiogenesis and metastasis in esophageal squamous cell carcinoma. Proceedings of the National Academy of Sciences of the United States of America 120 (42) (2023)
Yongxu Jia, Bai-Feng Zhang, Chunyang Zhang, Dora Lai-Wan Kwong, Zhiwei Chang, Shanshan Li, Zehua Wang, Huiqiong Han, Jing Li, Yali Zhong, Xin Sui, Li Fu, Xin-Yuan Guan, Yanru Qin
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Esophageal Squamous Cell Carcinoma. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (7) (2023)
Lan-Qi Gong, Jie Luo, Yu Zhang, Yuma Yang, Shanshan Li, Xiaona Fang, Bai-Feng Zhang, Jiao Huang, Larry Ka-Yue Chow, Dittman Chung, Jinlin Huang, Cuicui Huang, Qin Liu, Lu Bai, Yuen Chak Tiu, Pingan Wu, Yan Wang, George Sai-Wah Tsao, Dora Lai-Wan Kwong, Anne Wing-Mui Lee, Wei Dai, Xin-Yuan Guan
Nasopharyngeal carcinoma cells promote regulatory T cell development and suppressive activity via CD70-CD27 interaction. Nature communications 14 (1) (2023)
Yuen Chak Tiu, Lanqi Gong, Yu Zhang, Jie Luo, Yuma Yang, Ying Tang, Wing-Mui Lee, Xin-Yuan Guan
GLIPR1 promotes proliferation, metastasis and 5-fluorouracil resistance in hepatocellular carcinoma by activating the PI3K/PDK1/ROCK1 pathway. Cancer gene therapy 29 (11) (2022)
Qian Yan, Xiaona Fang, Chenxi Li, Ping Lan, Xin-Yuan Guan
Oncofetal proteins and cancer stem cells. Essays in biochemistry 66 (4) (2022)
Yu Zhang, Trang Vu, Douglas C Palmer, Rigel J Kishton, Lanqi Gong, Jiao Huang, Thanh Nguyen, Zuojia Chen, Cari Smith, Ferenc Livák, Rohit Paul, Chi-Ping Day, Chuan Wu, Glenn Merlino, Kenneth D Aldape, Xin-Yuan Guan, Peng Jiang
A T cell resilience model associated with response to immunotherapy in multiple tumor types. Nature medicine 28 (7) (2022)
Ting-Ting Zeng, Tian-Hao Deng, Zhen Liu, Jia-Rong Zhan, Yuan-Zhen Ma, Yuan-Yuan Yan, Xiao Sun, Ying-Hui Zhu, Yan Li, Xin-Yuan Guan, Lei Li
HN1L/AP-2γ/PLK1 signaling drives tumor progression and chemotherapy resistance in esophageal squamous cell carcinoma. Cell death & disease 13 (12) (2022)
Liangzhan Sun, Shaoyan Xi, Zhengdong Zhou, Feifei Zhang, Pengchao Hu, Yuzhu Cui, Shasha Wu, Ying Wang, Shayi Wu, Yanchen Wang, Yuyang Du, Jingyi Zheng, Hui Yang, Miao Chen, Qian Yan, Dandan Yu, Chaoran Shi, Yu Zhang, Dan Xie, Xin-Yuan Guan, Yan Li
Elevated expression of RIT1 hyperactivates RAS/MAPK signal and sensitizes hepatocellular carcinoma to combined treatment with sorafenib and AKT inhibitor. Oncogene (2021)
Xia Wang, Jin Wang, Yu-Man Tsui, Chaoran Shi, Ying Wang, Xin Zhang, Qian Yan, Miao Chen, Chen Jiang, Yichuan Yuan, Chun Ming Wong, Ming Liu, Zeng-Yu Feng, Hong-Lin Chen, Irene Oi Lin Ng, Lingxi Jiang, Xin-Yuan Guan
RALYL increases hepatocellular carcinoma stemness by sustaining the mRNA stability of TGF-β2. Nature communications 12 (1) (2021)
Ya-Nan Tan, Jian-Dong Huang, Yong-Peng Li, Shan-Shan Li, Min Luo, Jie Luo, Anne Wing-Mui Lee, Li Fu, Fu-Qiang Hu, Xin-Yuan Guan
Near-infrared Responsive Membrane Nanovesicles Amplify Homologous Targeting Delivery of anti-PD Immunotherapy Against Metastatic Tumors. Advanced healthcare materials (2021)
Fan-En Kong, Guang-Meng Li, Yun-Qiang Tang, Shao-Yan Xi, Jane Ho Chun Loong, Mei-Mei Li, Hao-Long Li, Wei Cheng, Wen-Jie Zhu, Jia-Qiang Mo, Yuan-Feng Gong, Hui Tang, Yue Zhao, Yan Zhang, Stephianie Ma, Xin-Yuan Guan, Ning-Fang Ma, Mao-Bin Xie, Ming Liu
Targeting tumor lineage plasticity in hepatocellular carcinoma using an anti-CLDN6 antibody-drug conjugate. Science translational medicine 13 (579) (2021)
Yinli Zheng, Jinjun Wu, Ru Deng, Censhan Lin, Yuhua Huang, Xia Yang, Chunhua Wang, Mingming Yang, Yangfan He, Jiabin Lu, Xiaodong Su, Qian Yan, Ying-Hui Zhu, Xin-Yuan Guan, Yan Li, Jing-Ping Yun
G3BP2 regulated by the lncRNA LINC01554 facilitates esophageal squamous cell carcinoma metastasis through stabilizing HDGF transcript. Oncogene (2021)
Lei Li, Jia-Ru Wei, Jun Dong, Qing-Guang Lin, Hong Tang, Yong-Xu Jia, Wanlin Tan, Qing-Yun Chen, Ting-Ting Zeng, Shan Xing, Yan-Ru Qin, Ying-Hui Zhu, Yan Li, Xin-Yuan Guan
Laminin γ2-mediating T cell exclusion attenuates response to anti-PD-1 therapy. Science advances 7 (6) (2021)
Qian Yan, Yu Zhang, Xiaona Fang, Bei-Lei Liu, Tin-Lok Wong, Lanqi Gong, Shan Liu, Dandan Yu, Ming Liu, Lingxi Jiang, Xia Wang, Ting Wei, Yongxu Jia, Lei Li, Liangzhan Sun, Ying Tang, Ningning Zhou, Yun-Fei Yuan, Yan Li, Stephianie Ma, Xin-Yuan Guan
PGC7 promotes tumor oncogenic dedifferentiation through remodeling DNA methylation pattern for key developmental transcription factors. Cell death and differentiation 28 (6) (2021)
Wen Wen Xu, Can-Can Zheng, Qian Zuo, Jun-Qi Li, Pan Hong, Yan-Ru Qin, Xin-Yuan Guan, Qing-Yu He, Hua-Xin Liao, Bin Li
Genome-wide identification of key regulatory lncRNAs in esophageal cancer metastasis. Signal transduction and targeted therapy 6 (1) (2021)
Xiaofeng Zhang, Yinshan Bai, Li Huang, Shanshan Liu, Yanxuan Mo, Wei Cheng, Guangliang Wang, Zhiming Cao, Xiaogang Chen, Huiqing Cui, Ling Qi, Lei Ma, Ming Liu, Xin-Yuan Guan, Ning-Fang Ma
CHD1L augments autophagy-mediated migration of hepatocellular carcinoma through targeting ZKSCAN3. Cell death & disease 12 (10) (2021)
Wei Cheng, Hao-Long Li, Shao-Yan Xi, Xiao-Feng Zhang, Yun Zhu, null Le Xing, Yan-Xuan Mo, Mei-Mei Li, Fan-En Kong, Wen-Jie Zhu, Xiao-Gang Chen, Hui-Qing Cui, Zhi-Ming Cao, Yuan-Feng Gong, Yun-Qiang Tang, Yan Zhang, Xin-Yuan Guan, Ning-Fang Ma, Ming Liu
Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma. Nature communications 12 (1) (2021)
Lanqi Gong, Dora Lai-Wan Kwong, Wei Dai, Pingan Wu, Shanshan Li, Qian Yan, Yu Zhang, Bai-Feng Zhang, Xiaona Fang, Li Liu, Min Luo, Bei-Lei Liu, Larry Ka-Yue Chow, Qingyun Chen, Jinlin Huang, Victor Ho-Fun Lee, Ka-On Lam, Anthony Wing-Ip Lo, Zhiwei Chen, Yan Wang, Anne Wing-Mui Lee, Xin-Yuan Guan
Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma. Nature communications 12 (1) (2021)
Terence Kin-Wah Lee, Xin-Yuan Guan, Stephianie Ma
Cancer stem cells in hepatocellular carcinoma - from origin to clinical implications. Nature reviews. Gastroenterology & hepatology (2021)
Lei Li, Jia-Ru Wei, Ye Song, Shuo Fang, Yanyu Du, Zhuo Li, Ting-Ting Zeng, Ying-Hui Zhu, Yan Li, Xin-Yuan Guan
TROAP switches DYRK1 activity to drive hepatocellular carcinoma progression. Cell death & disease 12 (1) (2021)
Xintao Yang, Feng Hu, Jessica Aijia Liu, Shan Yu, May Pui Lai Cheung, Xuelai Liu, Irene Oi Lin Ng, Xin-Yuan Guan, Kelvin K W Wong, Rakesh Sharma, Hong Lok Lung, Yufei Jiao, Leo Tsz On Lee, Martin C H Cheung
Nuclear DLC1 exerts oncogenic function through association with FOXK1 for cooperative activation of MMP9 expression in melanoma. Oncogene 39 (20) (2020)
Ming Liu, Qian Yan, Yi Sun, Yoonhee Nam, Liang Hu, Jane Hc Loong, Qi Ouyang, Yu Zhang, Hao-Long Li, Fan-En Kong, Lei Li, Yan Li, Mei-Mei Li, Wei Cheng, Ling-Xi Jiang, Shuo Fang, Xiao-Dong Yang, Jia-Qiang Mo, Yuan-Feng Gong, Yun-Qiang Tang, Yan Li, Yun-Fei Yuan, Ning-Fang Ma, Ge Lin, Stephanie Ma, Ji-Guang Wang, Xin-Yuan Guan
A hepatocyte differentiation model reveals two subtypes of liver cancer with different oncofetal properties and therapeutic targets. Proceedings of the National Academy of Sciences of the United States of America 117 (11) (2020)
Dan Liao, Li Zhong, Junqiang Yin, Cuiling Zeng, Xin Wang, Xingchuan Huang, Gina Jinna Chen, Hong Zhang, Ruhua Zhang, Xin-Yuan Guan, Xintao Shuai, Jianhua Sui, Song Gao, Wuguo Deng, Yi-Xin Zeng, Jing-Nan Shen, Jian Chen, Tie-Bang Kang
Chromosomal translocation-derived aberrant Rab22a drives metastasis of osteosarcoma. Nature cell biology 22 (7) (2020)
Daqin Suo, Ling Wang, Tingting Zeng, Hui Zhang, Lei Li, Jinyun Liu, Jingping Yun, Xin-Yuan Guan, Yan Li
NRIP3 upregulation confers resistance to chemoradiotherapy in ESCC via RTF2 removal by accelerating ubiquitination and degradation of RTF2. Oncogenesis 9 (8) (2020)
Guan-Man Li, Lei Li, Meng-Qing Li, Xu Chen, Qiao Su, Zhi-Juan Deng, Hai-Bo Liu, Bin Li, Wen-Hui Zhang, Yong-Xu Jia, Wen-Jian Wang, Jie-Yi Ma, Hai-Liang Zhang, Dan Xie, Xiao-Feng Zhu, Yu-Long He, Xin-Yuan Guan, Jiong Bi
DAPK3 inhibits gastric cancer progression via activation of ULK1-dependent autophagy. Cell death and differentiation 28 (3) (2020)
Xuming Tang, Tingting Cao, Yun Zhu, Liyi Zhang, Gina Jinna Chen, Tengfei Liu, Xiaoyan Ming, Shuo Fang, Yichuan Yuan, Lingxi Jiang, Jian-Dong Huang, Xin-Yuan Guan
PIM2 promotes hepatocellular carcinoma tumorigenesis and progression through activating NF-κB signaling pathway. Cell death & disease 11 (7) (2020)
Daqin Suo, Zi-Feng Wang, Lei Li, Qingyun Chen, Tingting Zeng, Ran-Yi Liu, Jingping Yun, Xin-Yuan Guan, Yan Li
HOXC10 upregulation confers resistance to chemoradiotherapy in ESCC tumor cells and predicts poor prognosis. Oncogene 39 (32) (2020)
Yu Zhang, Qian Yan, Lanqi Gong, Hang Xu, Beilei Liu, Xiaona Fang, Dandan Yu, Lei Li, Ting Wei, Ying Wang, Ching Ngar Wong, Zhaojie Lyu, Ying Tang, Pak Chung Sham, Xin-Yuan Guan
C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism. Oncogene 40 (6) (2020)
Shuo Fang, Ming Liu, Lei Li, Fei-Fei Zhang, Yun Li, Qian Yan, Yu-Zhu Cui, Ying-Hui Zhu, Yun-Fei Yuan, Xin-Yuan Guan
Lymphoid enhancer-binding factor-1 promotes stemness and poor differentiation of hepatocellular carcinoma by directly activating the NOTCH pathway. Oncogene 38 (21) (2019)
Hong Tang, Lingxi Jiang, Cailei Zhu, Raymond Liu, Yufeng Wu, Qian Yan, Ming Liu, Yongxu Jia, Juan Chen, Yanru Qin, Victor Ho-Fun Lee, Suxia Luo, Qiming Wang, Xin-Yuan Guan
Loss of cell adhesion molecule L1 like promotes tumor growth and metastasis in esophageal squamous cell carcinoma. Oncogene 38 (17) (2019)
Lei Li, Yin-Li Zheng, Chen Jiang, Shuo Fang, Ting-Ting Zeng, Ying-Hui Zhu, Yan Li, Dan Xie, Xin-Yuan Guan
HN1L-mediated transcriptional axis AP-2γ/METTL13/TCF3-ZEB1 drives tumor growth and metastasis in hepatocellular carcinoma. Cell death and differentiation 26 (11) (2019)
Baozhu Zhang, Zhao Zhang, Lei Li, Yan-Ru Qin, Haibo Liu, Chen Jiang, Ting-Ting Zeng, Meng-Qing Li, Dan Xie, Yan Li, Xin-Yuan Guan, Ying-Hui Zhu
TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-κB signaling. Nature communications 9 (1) (2018)
Xing Tian, Chang Liu, Xin Wang, Fei Wang, Liqun Wang, Lu Xu, Jinfa Ma, Yating Gao, Yantao Bao, Falin Wang, Luyao Sun, Junni Wei, Chuwen Lin, He Zhang, Gang Zhu, Xin-Yuan Guan, Songbin Fu, Chunyu Zhang
Sei-1 promotes double minute chromosomes formation through activation of the PI3K/Akt/BRCA1-Abraxas pathway and induces double-strand breaks in NIH-3T3 fibroblasts. Cell death & disease 9 (3) (2018)
Lei Li, Hong Yang, Yan Li, Xiao-Dong Li, Ting-Ting Zeng, Su-Xia Lin, Ying-Hui Zhu, Xin-Yuan Guan
Hypoxia restrains the expression of complement component 9 in tumor-associated macrophages promoting non-small cell lung cancer progression. Cell death discovery 4 (2018)
Lei Li, Jiang-Chao Li, Hong Yang, Xu Zhang, Lu-Lu Liu, Yan Li, Ting-Ting Zeng, Ying-Hui Zhu, Xiao-Dong Li, Yan Li, Dan Xie, Li Fu, Xin-Yuan Guan
Expansion of cancer stem cell pool initiates lung cancer recurrence before angiogenesis. Proceedings of the National Academy of Sciences of the United States of America 115 (38) (2018)
Patrick Ming-Kuen Tang, Shuang Zhou, Xiao-Ming Meng, Qing-Ming Wang, Chun-Jie Li, Guang-Yu Lian, Xiao-Ru Huang, Yong-Jiang Tang, Xin-Yuan Guan, Bryan Ping-Yen Yan, Ka-Fai To, Hui-Yao Lan
Smad3 promotes cancer progression by inhibiting E4BP4-mediated NK cell development. Nature communications 8 (2017)
Fu Peng, Hailin Tang, Peng Liu, Jiangang Shen, Xin-Yuan Guan, Xiaofang Xie, Jihai Gao, Liang Xiong, Lei Jia, Jianping Chen, Cheng Peng
Isoliquiritigenin modulates miR-374a/PTEN/Akt axis to suppress breast cancer tumorigenesis and metastasis. Scientific reports 7 (1) (2017)
Li Fu, Yan-Ru Qin, Xiao-Yan Ming, Xian-Bo Zuo, Yu-Wen Diao, Li-Yi Zhang, Jiaoyu Ai, Bei-Lei Liu, Tu-Xiong Huang, Ting-Ting Cao, Bin-Bin Tan, Di Xiang, Chui-Mian Zeng, Jing Gong, Qiangfeng Zhang, Sui-Sui Dong, Juan Chen, Haibo Liu, Jian-Lin Wu, Robert Z Qi, Dan Xie, Li-Dong Wang, Xin-Yuan Guan
RNA editing of SLC22A3 drives early tumor invasion and metastasis in familial esophageal cancer. Proceedings of the National Academy of Sciences of the United States of America 114 (23) (2017)
Xiao-Yan Ming, Li Fu, Li-Yi Zhang, Yan-Ru Qin, Ting-Ting Cao, Kwok Wah Chan, Stephanie Ma, Dan Xie, Xin-Yuan Guan
Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma. Nature communications 7 (2016)
Stella Chai, Kai-Yu Ng, Man Tong, Eunice Y Lau, Terence K Lee, Kwok Wah Chan, Yun-Fei Yuan, Tan-To Cheung, Siu-Tim Cheung, Xiao-Qi Wang, Nathalie Wong, Chung-Mau Lo, Kwan Man, Xin-Yuan Guan, Stephanie Ma
Octamer 4/microRNA-1246 signaling axis drives Wnt/β-catenin activation in liver cancer stem cells. Hepatology (Baltimore, Md.) 64 (6) (2016)