Yong Huang

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 49

Top Topics

Advanced Non Small Cell Lung Cancer

Staphylococcus Aureus

Top Venues

Molecular pharmaceutics

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Xueqiong Feng, Zhongqing Wen, Xiangcheng Zhu, Xiaohui Yan, Yanwen Duan, Yong Huang
Anti-HER2 Immunoliposomes: Antitumor Efficacy Attributable to Targeted Delivery of Anthraquinone-Fused Enediyne. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (17) (2024)
Zhongqing Wen, Zhoukang Zhuang, Huiming Liu, Zilong Wang, Xueqiong Feng, Xiangcheng Zhu, Xiaohui Yan, Yanwen Duan, Yong Huang
DNA Interaction and Cleavage Modes of Anthraquinone-Fused Enediynes: A Study on Tiancimycins, Yangpumicins, and Their Semisynthetic Analogues. Journal of medicinal chemistry 67 (6) (2024)
Xueqiong Feng, Zhongqing Wen, Xiangcheng Zhu, Xiaohui Yan, Yanwen Duan, Yong Huang
Anti-HER2 Immunoliposomes: Antitumor Efficacy Attributable to Targeted Delivery of Anthraquinone-Fused Enediyne. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2024)
Zhongqing Wen, Zhoukang Zhuang, Huiming Liu, Zilong Wang, Xueqiong Feng, Xiangcheng Zhu, Xiaohui Yan, Yanwen Duan, Yong Huang
DNA Interaction and Cleavage Modes of Anthraquinone-Fused Enediynes: A Study on Tiancimycins, Yangpumicins, and Their Semisynthetic Analogues. Journal of medicinal chemistry 67 (6) (2024)
Xueqiong Feng, Zhongqing Wen, Xiangcheng Zhu, Xiaohui Yan, Yanwen Duan, Yong Huang
Anti-HER2 Immunoliposomes: Antitumor Efficacy Attributable to Targeted Delivery of Anthraquinone-Fused Enediyne. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (17) (2024)
Xueqiong Feng, Zhongqing Wen, Xiangcheng Zhu, Xiaohui Yan, Yanwen Duan, Yong Huang
Anti-HER2 Immunoliposomes: Antitumor Efficacy Attributable to Targeted Delivery of Anthraquinone-Fused Enediyne. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (17) (2024)
Zhongqing Wen, Zhoukang Zhuang, Huiming Liu, Zilong Wang, Xueqiong Feng, Xiangcheng Zhu, Xiaohui Yan, Yanwen Duan, Yong Huang
DNA Interaction and Cleavage Modes of Anthraquinone-Fused Enediynes: A Study on Tiancimycins, Yangpumicins, and Their Semisynthetic Analogues. Journal of medicinal chemistry (2024)
Xueqiong Feng, Zhongqing Wen, Xiangcheng Zhu, Xiaohui Yan, Yanwen Duan, Yong Huang
Anti-HER2 Immunoliposomes: Antitumor Efficacy Attributable to Targeted Delivery of Anthraquinone-Fused Enediyne. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (17) (2024)
Jie Shi, Dian Peng, Fei-Fei Peng, Qing-Bo Zhang, Yan-Wen Duan, Yong Huang
The Isolation and Structure Elucidation of Spirotetronate Lobophorins A, B, and H8 from Streptomyces sp. CB09030 and Their Biosynthetic Gene Cluster. Molecules (Basel, Switzerland) 28 (8) (2023)
Jie Shi, Dian Peng, Fei-Fei Peng, Qing-Bo Zhang, Yan-Wen Duan, Yong Huang
The Isolation and Structure Elucidation of Spirotetronate Lobophorins A, B, and H8 from Streptomyces sp. CB09030 and Their Biosynthetic Gene Cluster. Molecules (Basel, Switzerland) 28 (8) (2023)
Jie Shi, Dian Peng, Fei-Fei Peng, Qing-Bo Zhang, Yan-Wen Duan, Yong Huang
The Isolation and Structure Elucidation of Spirotetronate Lobophorins A, B, and H8 from Streptomyces sp. CB09030 and Their Biosynthetic Gene Cluster. Molecules (Basel, Switzerland) 28 (8) (2023)
Hong Pu, Dian Peng, Genyun Tang, Qingxian Ma, Huaiyi Huang, Yani Zhong, Jiayao Long, Xueshuang Huang, Yanwen Duan, Yong Huang
Diaporpyrone E, an undescribed α-pyrone from the endophytic fungus Diaporthe sp. CB10100. Natural product research (2023)
Jie Shi, Dian Peng, Fei-Fei Peng, Qing-Bo Zhang, Yan-Wen Duan, Yong Huang
The Isolation and Structure Elucidation of Spirotetronate Lobophorins A, B, and H8 from Streptomyces sp. CB09030 and Their Biosynthetic Gene Cluster. Molecules (Basel, Switzerland) 28 (8) (2023)
Xin Chen, Chengcheng Lu, Yanwen Duan, Yong Huang
Recent Advancements in Drug Delivery of Sinomenine, A Disease-Modifying Anti-Rheumatic Drug. Pharmaceutics 14 (12) (2022)
Jian Pan, Qingwen Tan, Saibin Zhu, Xiaohui Yan, Yu Li, Zhoukang Zhuang, Xiangcheng Zhu, Yanwen Duan, Yong Huang
Discovery of pentaene polyols by the activation of an enediyne gene cluster: biosynthetic implications for 9-membered enediyne core structures. Chemical science 13 (45) (2022)
Xin Chen, Duanxiu Li, Hailu Zhang, Yanwen Duan, Yong Huang
Co-amorphous Systems of Sinomenine with Platensimycin or Sulfasalazine: Physical Stability and Excipient-Adjusted Release Behavior. Molecular pharmaceutics 19 (11) (2022)
Xueqiong Feng, Huiming Liu, Jian Pan, Yi Xiong, Xiangcheng Zhu, Xiaohui Yan, Yanwen Duan, Yong Huang
Liposome-Encapsulated Tiancimycin A Is Active against Melanoma and Metastatic Breast Tumors: The Effect of cRGD Modification of the Liposomal Carrier and Tiancimycin A Dose on Drug Activity and Toxicity. Molecular pharmaceutics 19 (4) (2022)
Xin Chen, Chengcheng Lu, Yanwen Duan, Yong Huang
Recent Advancements in Drug Delivery of Sinomenine, A Disease-Modifying Anti-Rheumatic Drug. Pharmaceutics 14 (12) (2022)
Xin Chen, Chengcheng Lu, Yanwen Duan, Yong Huang
Recent Advancements in Drug Delivery of Sinomenine, A Disease-Modifying Anti-Rheumatic Drug. Pharmaceutics 14 (12) (2022)
Hong Pu, Ting Jiang, Dian Peng, Juanjuan Xia, Juan Gao, Yeji Wang, Xiaohui Yan, Xueshuang Huang, Yanwen Duan, Yong Huang
Degradation of mirubactin to multiple siderophores with varying Fe(III) chelation properties. Organic & biomolecular chemistry 20 (25) (2022)
Danfeng Cao, Jie Yang, Youchao Deng, Meng Su, Yeji Wang, Xueqiong Feng, Yi Xiong, Enhe Bai, Yanwen Duan, Yong Huang
Discovery of a mammalian FASN inhibitor against xenografts of non-small cell lung cancer and melanoma. Signal transduction and targeted therapy 7 (1) (2022)
Dandan Hu, Xin Chen, Duanxiu Li, Hailu Zhang, Yanwen Duan, Yong Huang
Sustained Release of Co-Amorphous Matrine-Type Alkaloids and Resveratrol with Anti-COVID-19 Potential. Pharmaceutics 14 (3) (2022)
Youchao Deng, Yuling Li, Zhongqing Wen, Claudia H Ruiz, Xiang Weng, Michael D Cameron, Yanwen Duan, Yong Huang
Morphing Natural Product Platensimycin via Heck, Sonogashira, and One-Pot Sonogashira/Cycloaddition Reactions to Produce Antibiotics with In Vivo Activity. Antibiotics (Basel, Switzerland) 11 (4) (2022)
Xin Chen, Chengcheng Lu, Yanwen Duan, Yong Huang
Recent Advancements in Drug Delivery of Sinomenine, A Disease-Modifying Anti-Rheumatic Drug. Pharmaceutics 14 (12) (2022)
Jian Pan, Qingwen Tan, Saibin Zhu, Xiaohui Yan, Yu Li, Zhoukang Zhuang, Xiangcheng Zhu, Yanwen Duan, Yong Huang
Discovery of pentaene polyols by the activation of an enediyne gene cluster: biosynthetic implications for 9-membered enediyne core structures. Chemical science 13 (45) (2022)
Bang Gong, Enhe Bai, Xueqiong Feng, Liwei Yi, Yeji Wang, Xin Chen, Xiangcheng Zhu, Yanwen Duan, Yong Huang
Characterization of Chalkophomycin, a Copper(II) Metallophore with an Unprecedented Molecular Architecture. Journal of the American Chemical Society (2021)
Meng Su, Danfeng Cao, Zhe Wang, Yanwen Duan, Yong Huang
Fatty Acid Synthase Inhibitor Platensimycin Intervenes the Development of Nonalcoholic Fatty Liver Disease in a Mouse Model. Biomedicines 10 (1) (2021)
Zhe Wang, Xingyun Liu, Yanwen Duan, Yong Huang
Nanoparticle-Hydrogel Systems Containing Platensimycin for Local Treatment of Methicillin-Resistant Staphylococcus aureus Infection. Molecular pharmaceutics 18 (11) (2021)
Saibin Zhu, Yeji Wang, Zhongqing Wen, Yanwen Duan, Yong Huang
Discovery of a DNA Topoisomerase I Inhibitor Huanglongmycin N and Its Congeners from Streptomyces sp. CB09001. The Journal of organic chemistry 86 (23) (2021)
Zilong Wang, Runze Sun, Miao Li, Ling Liu, Yanwen Duan, Yong Huang
Yield improvement of enediyne yangpumicins in Micromonospora yangpuensis through ribosome engineering and fermentation optimization. Biotechnology journal 16 (12) (2021)
Yeji Wang, Shuo Wu, Yanwen Duan, Yong Huang
A point cloud-based deep learning strategy for protein-ligand binding affinity prediction. Briefings in bioinformatics (2021)
Lin Jiang, Jingxi Xiang, Saibin Zhu, Danfeng Tang, Bang Gong, Hong Pu, Yanwen Duan, Yong Huang
Undescribed benzophenone and xanthones from cave-derived Streptomyces sp. CB09001. Natural product research (2020)
Wenqing Zhou, Haoyu Liang, Xiangjing Qin, Danfeng Cao, Xiangcheng Zhu, Jianhua Ju, Ben Shen, Yanwen Duan, Yong Huang
The Isolation of Pyrroloformamide Congeners and Characterization of Their Biosynthetic Gene Cluster. Journal of natural products 83 (2) (2020)
Xingyun Liu, Zhe Wang, Xueqiong Feng, Enhe Bai, Yi Xiong, Xiangcheng Zhu, Ben Shen, Yanwen Duan, Yong Huang
Platensimycin-Encapsulated Poly(lactic-co-glycolic acid) and Poly(amidoamine) Dendrimers Nanoparticles with Enhanced Anti-Staphylococcal Activity in Vivo. Bioconjugate chemistry 31 (5) (2020)
Ling Liu, Sainan Li, Runze Sun, Xiangjing Qin, Jianhua Ju, Changsheng Zhang, Yanwen Duan, Yong Huang
Activation and Characterization of Bohemamine Biosynthetic Gene Cluster from Streptomyces sp. CB02009. Organic letters 22 (12) (2020)
Zhe Wang, Xingyun Liu, Ying Peng, Meng Su, Saibin Zhu, Jian Pan, Ben Shen, Yanwen Duan, Yong Huang
Platensimycin-Encapsulated Liposomes or Micelles as Biosafe Nanoantibiotics Exhibited Strong Antibacterial Activities against Methicillin-Resistant Staphylococcus aureus Infection in Mice. Molecular pharmaceutics 17 (7) (2020)
Haoyu Liang, Lin Jiang, Qiyun Jiang, Jie Shi, Jingxi Xiang, Xiaohui Yan, Xiangcheng Zhu, Lixing Zhao, Ben Shen, Yanwen Duan, Yong Huang
A 3-hydroxy-3-methylglutaryl-CoA synthase-based probe for the discovery of the acyltransferase-less type I polyketide synthases. Environmental microbiology 21 (11) (2019)
Meng Su, Lin Qiu, Youchao Deng, Claudia H Ruiz, Jeffrey D Rudolf, Liao-Bin Dong, Xueqiong Feng, Michael D Cameron, Ben Shen, Yanwen Duan, Yong Huang
Evaluation of Platensimycin and Platensimycin-Inspired Thioether Analogues against Methicillin-Resistant Staphylococcus aureus in Topical and Systemic Infection Mouse Models. Molecular pharmaceutics 16 (7) (2019)
Saibin Zhu, Yanwen Duan, Yong Huang
The Application of Ribosome Engineering to Natural Product Discovery and Yield Improvement in Streptomyces. Antibiotics (Basel, Switzerland) 8 (3) (2019)
Zhengren Xu, Shi-Ming Fang, Malina A Bakowski, Mostafa E Rateb, Dong Yang, Xiangcheng Zhu, Yong Huang, Li-Xing Zhao, Yi Jiang, Yanwen Duan, Mitchell V Hull, Case W McNamara, Ben Shen
Discovery of Kirromycins with Anti- Wolbachia Activity from Streptomyces sp. CB00686. ACS chemical biology 14 (6) (2019)
Youchao Deng, Xiang Weng, Yuling Li, Meng Su, Zhongqing Wen, Xinxin Ji, Nan Ren, Ben Shen, Yanwen Duan, Yong Huang
Late-Stage Functionalization of Platensimycin Leading to Multiple Analogues with Improved Antibacterial Activity in Vitro and in Vivo. Journal of medicinal chemistry 62 (14) (2019)
Lin Jiang, Hong Pu, Xiangjing Qin, Jianxin Liu, Zhongqing Wen, Yimin Huang, Jingxi Xiang, Yunxi Xiang, Jianhua Ju, Yanwen Duan, Yong Huang
Syn-2, 3-diols and anti-inflammatory indole derivatives from Streptomyces sp. CB09001. Natural product research 35 (1) (2019)
Zilong Wang, Zhongqing Wen, Ling Liu, Xiangcheng Zhu, Ben Shen, Xiaohui Yan, Yanwen Duan, Yong Huang
Yangpumicins F and G, Enediyne Congeners from Micromonospora yangpuensis DSM 45577. Journal of natural products 82 (9) (2019)
Youchao Deng, Meng Su, Dingding Kang, Xingyun Liu, Zhongqing Wen, Yuling Li, Lin Qiu, Ben Shen, Yanwen Duan, Yong Huang
Semisynthesis of Platensimycin Derivatives with Antibiotic Activities in Mice via Suzuki-Miyaura Cross-Coupling Reactions. Journal of medicinal chemistry 61 (24) (2018)
Xiaohui Yan, null Hindra, Hui Ming Ge, Dong Yang, Tingting Huang, Ivana Crnovcic, Chin-Yuan Chang, Shi-Ming Fang, Thibault Annaval, Xiangcheng Zhu, Yong Huang, Li-Xing Zhao, Yi Jiang, Yanwen Duan, Ben Shen
Discovery of Alternative Producers of the Enediyne Antitumor Antibiotic C-1027 with High Titers. Journal of natural products 81 (3) (2018)
Youchao Deng, Dingding Kang, Jie Shi, Wenqing Zhou, Aijun Sun, Jianhua Ju, Xiangcheng Zhu, Ben Shen, Yanwen Duan, Yong Huang
The semi-synthesis, biological evaluation and docking analysis of the oxime, hydrazine and hydrazide derivatives of platensimycin. MedChemComm 9 (5) (2018)
Ling Liu, Jian Pan, Zilong Wang, Xiaohui Yan, Dong Yang, Xiangcheng Zhu, Ben Shen, Yanwen Duan, Yong Huang
Ribosome engineering and fermentation optimization leads to overproduction of tiancimycin A, a new enediyne natural product from Streptomyces sp. CB03234. Journal of industrial microbiology & biotechnology 45 (3) (2018)
Lin Qiu, Kai Tian, Zhongqing Wen, Youchao Deng, Dingding Kang, Haoyu Liang, Xiangcheng Zhu, Ben Shen, Yanwen Duan, Yong Huang
Biomimetic Stereoselective Sulfa-Michael Addition Leads to Platensimycin and Platencin Sulfur Analogues against Methicillin-Resistant Staphylococcus aureus. Journal of natural products 81 (2) (2018)
Jian-Jun Chen, Mostafa E Rateb, Melissa S Love, Zhengren Xu, Dong Yang, Xiangcheng Zhu, Yong Huang, Li-Xing Zhao, Yi Jiang, Yanwen Duan, Case W McNamara, Ben Shen
Herbicidins from Streptomyces sp. CB01388 Showing Anti- Cryptosporidium Activity. Journal of natural products 81 (4) (2018)