Yosuke Demizu

Scopus Author ID Researcher Name Resolver ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 53

Top Topics

Estrogen Receptor

Top Venues

Organic letters

ACS medicinal chemistry letters

Expert opinion on drug discovery

This page only lists publications with an associated author ORCID identifier.

Publications

Kazuya Kamata, Masami Kuriyama, Hironobu Tahara, Akira Nishikawa, Kosuke Yamamoto, Yosuke Demizu, Osamu Onomura
One-pot C(sp 3 )-H difluoroalkylation of tetrahydroisoquinolines and isochromans via electrochemical oxidation and organozinc alkylation. Chemical communications (Cambridge, England) (2024)
Kazuya Kamata, Masami Kuriyama, Hironobu Tahara, Akira Nishikawa, Kosuke Yamamoto, Yosuke Demizu, Osamu Onomura
One-pot C(sp 3 )-H difluoroalkylation of tetrahydroisoquinolines and isochromans via electrochemical oxidation and organozinc alkylation. Chemical communications (Cambridge, England) 60 (50) (2024)
Zhou Dongrui, Maho Miyamoto, Hidetomo Yokoo, Yosuke Demizu
Innovative peptide architectures: advancements in foldamers and stapled peptides for drug discovery. Expert opinion on drug discovery (2024)
Kazuya Kamata, Masami Kuriyama, Hironobu Tahara, Akira Nishikawa, Kosuke Yamamoto, Yosuke Demizu, Osamu Onomura
One-pot C(sp 3 )-H difluoroalkylation of tetrahydroisoquinolines and isochromans via electrochemical oxidation and organozinc alkylation. Chemical communications (Cambridge, England) 60 (50) (2024)
Zhou Dongrui, Maho Miyamoto, Hidetomo Yokoo, Yosuke Demizu
Innovative peptide architectures: advancements in foldamers and stapled peptides for drug discovery. Expert opinion on drug discovery 19 (6) (2024)
Zhou Dongrui, Maho Miyamoto, Hidetomo Yokoo, Yosuke Demizu
Innovative peptide architectures: advancements in foldamers and stapled peptides for drug discovery. Expert opinion on drug discovery 19 (6) (2024)
Kosuke Yamamoto, Kohei Torigoe, Masami Kuriyama, Yosuke Demizu, Osamu Onomura
(3+2) Cycloaddition of Heteroaromatic N -Ylides with Sulfenes. Organic letters (2024)
Kosuke Yamamoto, Kohei Torigoe, Masami Kuriyama, Yosuke Demizu, Osamu Onomura
(3+2) Cycloaddition of Heteroaromatic N -Ylides with Sulfenes. Organic letters 26 (4) (2024)
Takuji Shoda, Genichiro Tsuji, Maiko Kawamura, Takashi Kurohara, Takashi Misawa, Ruri Kikura-Hanajiri, Yosuke Demizu
Structural analysis of an lysergic acid diethylamide (LSD) analogue N-methyl-N-isopropyllysergamide (MiPLA): Insights from Rotamers in NMR spectra. Drug testing and analysis (2023)
Miyako Naganuma, Nobumichi Ohoka, Genichiro Tsuji, Takao Inoue, Mikihiko Naito, Yosuke Demizu
Structural Optimization of Decoy Oligonucleotide-Based PROTAC That Degrades the Estrogen Receptor. Bioconjugate chemistry (2023)
Keisuke Tsuchiya, Kanako Horikoshi, Minami Fujita, Motoharu Hirano, Maho Miyamoto, Hidetomo Yokoo, Yosuke Demizu
Development of Hydrophobic Cell-Penetrating Stapled Peptides as Drug Carriers. International journal of molecular sciences 24 (14) (2023)
Motoharu Hirano, Hidetomo Yokoo, Chihiro Goto, Makoto Oba, Takashi Misawa, Yosuke Demizu
Magainin 2-derived stapled peptides derived with the ability to deliver pDNA, mRNA, and siRNA into cells. Chemical science 14 (38) (2023)
Po-Chang Shih, Miyako Naganuma, Yosuke Demizu, Mikihiko Naito
Current Status of Oligonucleotide-Based Protein Degraders. Pharmaceutics 15 (3) (2023)
Hidetomo Yokoo, Mikihiko Naito, Yosuke Demizu
Investigating the cell permeability of proteolysis-targeting chimeras (PROTACs). Expert opinion on drug discovery (2023)
Rika Ishikawa, Kosuke Saito, Takashi Misawa, Yosuke Demizu, Yoshiro Saito
Identification of the Stapled α-Helical Peptide ATSP-7041 as a Substrate and Strong Inhibitor of OATP1B1 In Vitro. Biomolecules 13 (6) (2023)
Takahito Ito, Wakana Hashimoto, Nobumichi Ohoka, Takashi Misawa, Takao Inoue, Ryuji Kawano, Yosuke Demizu
Structure-Activity Relationship Study of Helix-Stabilized Antimicrobial Peptides Containing Nonproteinogenic Amino Acids. ACS biomaterials science & engineering (2023)
Takahito Ito, Hidetomo Yokoo, Takuma Kato, Mitsunobu Doi, Yosuke Demizu
Sculpting Secondary Structure of a Cyclic Peptide: Conformational Analysis of a Cyclic Hexapeptide Containing a Combination of l-Leu, d-Leu, and Aib Residues. ACS omega 8 (46) (2023)
Po-Chang Shih, Miyako Naganuma, Yosuke Demizu, Mikihiko Naito
Current Status of Oligonucleotide-Based Protein Degraders. Pharmaceutics 15 (3) (2023)
Rika Ishikawa, Kosuke Saito, Takashi Misawa, Yosuke Demizu, Yoshiro Saito
Identification of the Stapled α-Helical Peptide ATSP-7041 as a Substrate and Strong Inhibitor of OATP1B1 In Vitro. Biomolecules 13 (6) (2023)
Takahito Ito, Natsumi Matsunaga, Megumi Kurashima, Yosuke Demizu, Takashi Misawa
Enhancing Chemical Stability through Structural Modification of Antimicrobial Peptides with Non-Proteinogenic Amino Acids. Antibiotics (Basel, Switzerland) 12 (8) (2023)
Po-Chang Shih, Miyako Naganuma, Yosuke Demizu, Mikihiko Naito
Current Status of Oligonucleotide-Based Protein Degraders. Pharmaceutics 15 (3) (2023)
Rika Ishikawa, Kosuke Saito, Takashi Misawa, Yosuke Demizu, Yoshiro Saito
Identification of the Stapled α-Helical Peptide ATSP-7041 as a Substrate and Strong Inhibitor of OATP1B1 In Vitro. Biomolecules 13 (6) (2023)
Haruna Tsujimura, Miyako Naganuma, Nobumichi Ohoka, Takao Inoue, Mikihiko Naito, Genichiro Tsuji, Yosuke Demizu
Development of DNA Aptamer-Based PROTACs That Degrade the Estrogen Receptor. ACS medicinal chemistry letters 14 (6) (2023)
Kosuke Yamamoto, Yu Suganomata, Takumi Inoue, Masami Kuriyama, Yosuke Demizu, Osamu Onomura
Copper-Catalyzed Asymmetric Oxidative Desymmetrization of 2-Substituted 1,2,3-Triols. The Journal of organic chemistry 87 (9) (2022)
Yuki Murakami, Hinata Osawa, Takashi Kurohara, Yuta Yanase, Takahito Ito, Hidetomo Yokoo, Norihito Shibata, Mikihiko Naito, Kosuke Aritake, Yosuke Demizu
Structure-activity relationship study of PROTACs against hematopoietic prostaglandin D 2 synthase. RSC medicinal chemistry 13 (12) (2022)
Kotone Katagiri, Masami Kuriyama, Kosuke Yamamoto, Yosuke Demizu, Osamu Onomura
Organocatalytic Synthesis of Phenols from Diaryliodonium Salts with Water under Metal-Free Conditions. Organic letters 24 (28) (2022)
Hanqiao Xu, Takashi Kurohara, Reina Takano, Hidetomo Yokoo, Norihito Shibata, Nobumichi Ohoka, Takao Inoue, Mikihiko Naito, Yosuke Demizu
Development of Rapid and Facile Solid-Phase Synthesis of PROTACs via a Variety of Binding Styles. ChemistryOpen 11 (7) (2022)
Mami Takyo, Yumi Sato, Naoya Hirata, Keisuke Tsuchiya, Hiroaki Isida, Takashi Kurohara, Yuta Yanase, Takahito Ito, Yasunari Kanda, Keiko Yamamoto, Takashi Misawa, Yosuke Demizu
Oligoarginine-Conjugated Peptide Foldamers Inhibiting Vitamin D Receptor-Mediated Transcription. ACS omega 7 (50) (2022)
Mayu Takada, Takahito Ito, Megumi Kurashima, Natsumi Matsunaga, Yosuke Demizu, Takashi Misawa
Structure-Activity Relationship Studies of Substitutions of Cationic Amino Acid Residues on Antimicrobial Peptides. Antibiotics (Basel, Switzerland) 12 (1) (2022)
Nobumichi Ohoka, Masanori Suzuki, Takuya Uchida, Genichiro Tsuji, Yoshinori Tsukumo, Masayuki Yoshida, Takao Inoue, Yosuke Demizu, Hitoshi Ohki, Mikihiko Naito
Development of Gilteritinib-Based Chimeric Small Molecules that Potently Induce Degradation of FLT3-ITD Protein. ACS medicinal chemistry letters 13 (12) (2022)
Yuta Yanase, Genichiro Tsuji, Miki Nakamura, Norihito Shibata, Yosuke Demizu
Control of STING Agonistic/Antagonistic Activity Using Amine-Skeleton-Based c-di-GMP Analogues. International journal of molecular sciences 23 (12) (2022)
Hidetomo Yokoo, Miyako Naganuma, Makoto Oba, Yosuke Demizu
Recent Advances in PROTAC Technology Toward New Therapeutic Modalities. Chemistry & biodiversity 19 (11) (2022)
Nobumichi Ohoka, Masanori Suzuki, Takuya Uchida, Genichiro Tsuji, Yoshinori Tsukumo, Masayuki Yoshida, Takao Inoue, Yosuke Demizu, Hitoshi Ohki, Mikihiko Naito
Development of Gilteritinib-Based Chimeric Small Molecules that Potently Induce Degradation of FLT3-ITD Protein. ACS medicinal chemistry letters 13 (12) (2022)
Yuki Murakami, Hinata Osawa, Takashi Kurohara, Yuta Yanase, Takahito Ito, Hidetomo Yokoo, Norihito Shibata, Mikihiko Naito, Kosuke Aritake, Yosuke Demizu
Structure-activity relationship study of PROTACs against hematopoietic prostaglandin D 2 synthase. RSC medicinal chemistry 13 (12) (2022)
Hiroyuki Takada, Keisuke Tsuchiya, Yosuke Demizu
Helix-Stabilized Cell-Penetrating Peptides for Delivery of Antisense Morpholino Oligomers: Relationships among Helicity, Cellular Uptake, and Antisense Activity. Bioconjugate chemistry 33 (7) (2022)
Mami Takyo, Yumi Sato, Naoya Hirata, Keisuke Tsuchiya, Hiroaki Isida, Takashi Kurohara, Yuta Yanase, Takahito Ito, Yasunari Kanda, Keiko Yamamoto, Takashi Misawa, Yosuke Demizu
Oligoarginine-Conjugated Peptide Foldamers Inhibiting Vitamin D Receptor-Mediated Transcription. ACS omega 7 (50) (2022)
Mayu Takada, Takahito Ito, Megumi Kurashima, Natsumi Matsunaga, Yosuke Demizu, Takashi Misawa
Structure-Activity Relationship Studies of Substitutions of Cationic Amino Acid Residues on Antimicrobial Peptides. Antibiotics (Basel, Switzerland) 12 (1) (2022)
Motoharu Hirano, Chihiro Saito, Hidetomo Yokoo, Chihiro Goto, Ryuji Kawano, Takashi Misawa, Yosuke Demizu
Development of Antimicrobial Stapled Peptides Based on Magainin 2 Sequence. Molecules (Basel, Switzerland) 26 (2) (2021)
Hidetomo Yokoo, Motoharu Hirano, Takashi Misawa, Yosuke Demizu
Helical Antimicrobial Peptide Foldamers Containing Non-proteinogenic Amino Acids. ChemMedChem 16 (8) (2021)
Hidetomo Yokoo, Norihito Shibata, Akinori Endo, Takahito Ito, Yuta Yanase, Yuki Murakami, Kiyonaga Fujii, Kengo Hamamura, Yasushi Saeki, Mikihiko Naito, Kosuke Aritake, Yosuke Demizu
Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design. Journal of medicinal chemistry 64 (21) (2021)
Motoharu Hirano, Chihiro Saito, Chihiro Goto, Hidetomo Yokoo, Ryuji Kawano, Takashi Misawa, Yosuke Demizu
Rational Design of Helix-Stabilized Antimicrobial Peptide Foldamers Containing α,α-Disubstituted Amino Acids or Side-Chain Stapling. ChemPlusChem 85 (12) (2021)
Hidetomo Yokoo, Motoharu Hirano, Nobumichi Ohoka, Takashi Misawa, Yosuke Demizu
Structure-activity relationship study of amphipathic antimicrobial peptides using helix-destabilizing sarcosine. Journal of peptide science : an official publication of the European Peptide Society 27 (12) (2021)
Miyako Naganuma, Nobumichi Ohoka, Genichiro Tsuji, Haruna Tsujimura, Kenji Matsuno, Takao Inoue, Mikihiko Naito, Yosuke Demizu
Development of Chimeric Molecules That Degrade the Estrogen Receptor Using Decoy Oligonucleotide Ligands. ACS medicinal chemistry letters 13 (1) (2021)
Hidetomo Yokoo, Nobumichi Ohoka, Mami Takyo, Takahito Ito, Keisuke Tsuchiya, Takashi Kurohara, Kiyoshi Fukuhara, Takao Inoue, Mikihiko Naito, Yosuke Demizu
Peptide Stapling Improves the Sustainability of a Peptide-Based Chimeric Molecule That Induces Targeted Protein Degradation. International journal of molecular sciences 22 (16) (2021)
Hidetomo Yokoo, Takashi Misawa, Yosuke Demizu
De Novo Design of Cell-Penetrating Foldamers. Chemical record (New York, N.Y.) 20 (9) (2020)
Chihiro Goto, Motoharu Hirano, Katsuhiko Hayashi, Yutaka Kikuchi, Yukiko Hara-Kudo, Takashi Misawa, Yosuke Demizu
Development of Amphipathic Antimicrobial Peptide Foldamers Based on Magainin 2 Sequence. ChemMedChem 14 (22) (2019)
Takashi Misawa, Chihiro Goto, Norihito Shibata, Motoharu Hirano, Yutaka Kikuchi, Mikihiko Naito, Yosuke Demizu
Rational design of novel amphipathic antimicrobial peptides focused on the distribution of cationic amino acid residues. MedChemComm 10 (6) (2019)
Nobumichi Ohoka, Genichiro Tsuji, Takuji Shoda, Takuma Fujisato, Masaaki Kurihara, Yosuke Demizu, Mikihiko Naito
Development of Small Molecule Chimeras That Recruit AhR E3 Ligase to Target Proteins. ACS chemical biology 14 (12) (2019)
Yurie Koba, Atsushi Ueda, Makoto Oba, Mitsunobu Doi, Takuma Kato, Yosuke Demizu, Masakazu Tanaka
Left-Handed Helix of Three-Membered Ring Amino Acid Homopeptide Interrupted by an N-H···Ethereal O-Type Hydrogen Bond. Organic letters 20 (24) (2018)
Koyo Okitsu, Takayuki Hattori, Takashi Misawa, Takuji Shoda, Masaaki Kurihara, Mikihiko Naito, Yosuke Demizu
Development of a Small Hybrid Molecule That Mediates Degradation of His-Tag Fused Proteins. Journal of medicinal chemistry 61 (2) (2017)
Takashi Misawa, Yasunari Kanda, Yosuke Demizu
Rational Design and Synthesis of Post-Functionalizable Peptide Foldamers as Helical Templates. Bioconjugate chemistry 28 (12) (2017)
Hiroyuki Kobayashi, Takashi Misawa, Kenji Matsuno, Yosuke Demizu
Preorganized Cyclic α,α-Disubstituted α-Amino Acids Bearing Functionalized Side Chains That Act as Peptide-Helix Inducers. The Journal of organic chemistry 82 (19) (2017)
Nobuko Akiyama, Nobukazu Takizawa, Maki Miyauchi, Hiromi Yanai, Ryosuke Tateishi, Miho Shinzawa, Riko Yoshinaga, Masaaki Kurihara, Yosuke Demizu, Hisataka Yasuda, Shintaro Yagi, Guoying Wu, Mitsuru Matsumoto, Reiko Sakamoto, Nobuaki Yoshida, Josef M Penninger, Yasuhiro Kobayashi, Jun-Ichiro Inoue, Taishin Akiyama
Identification of embryonic precursor cells that differentiate into thymic epithelial cells expressing autoimmune regulator. The Journal of experimental medicine 213 (8) (2016)