Zachary D Nagel (Zachary Nagel, Z D Nagel)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 17

Top Topics

Gene Expression

Radiation Therapy

Escherichia Coli

Top Venues

Science translational medicine

Nature communications

Nature protocols

This page only lists publications with an associated author ORCID identifier.

Publications

Jiajia Chen, Daniel J Laverty, Surabhi Talele, Ashwin Bale, Brett L Carlson, Kendra A Porath, Katrina K Bakken, Danielle M Burgenske, Paul A Decker, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Rohit Bhargava, Zhenkun Lou, Petra Hamerlik, Brendan A C Harley, William F Elmquist, Zachary D Nagel, Shiv K Gupta, Jann N Sarkaria
Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization. Science translational medicine 16 (734) (2024)
Jiajia Chen, Daniel J Laverty, Surabhi Talele, Ashwin Bale, Brett L Carlson, Kendra A Porath, Katrina K Bakken, Danielle M Burgenske, Paul A Decker, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Rohit Bhargava, Zhenkun Lou, Petra Hamerlik, Brendan A C Harley, William F Elmquist, Zachary D Nagel, Shiv K Gupta, Jann N Sarkaria
Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization. Science translational medicine 16 (734) (2024)
Jiajia Chen, Daniel J Laverty, Surabhi Talele, Ashwin Bale, Brett L Carlson, Kendra A Porath, Katrina K Bakken, Danielle M Burgenske, Paul A Decker, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Rohit Bhargava, Zhenkun Lou, Petra Hamerlik, Brendan A C Harley, William F Elmquist, Zachary D Nagel, Shiv K Gupta, Jann N Sarkaria
Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization. Science translational medicine 16 (734) (2024)
Daniel J Laverty, Shiv K Gupta, Gary A Bradshaw, Alexander S Hunter, Brett L Carlson, Nery Matias Calmo, Jiajia Chen, Shulan Tian, Jann N Sarkaria, Zachary D Nagel
ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma. Nature communications 15 (1) (2024)
Jiajia Chen, Daniel J Laverty, Surabhi Talele, Ashwin Bale, Brett L Carlson, Kendra A Porath, Katrina K Bakken, Danielle M Burgenske, Paul A Decker, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Rohit Bhargava, Zhenkun Lou, Petra Hamerlik, Brendan A C Harley, William F Elmquist, Zachary D Nagel, Shiv K Gupta, Jann N Sarkaria
Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization. Science translational medicine 16 (734) (2024)
Aris A Polyzos, Ana Cheong, Jung Hyun Yoo, Lana Blagec, Sneh M Toprani, Zachary D Nagel, Cynthia T McMurray
Base excision repair and double strand break repair cooperate to modulate the formation of unrepaired double strand breaks in mouse brain. Nature communications 15 (1) (2024)
Daniel J Laverty, Shiv K Gupta, Gary A Bradshaw, Alexander S Hunter, Brett L Carlson, Nery Matias Calmo, Jiajia Chen, Shulan Tian, Jann N Sarkaria, Zachary D Nagel
ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma. Nature communications 15 (1) (2024)
Jiajia Chen, Daniel J Laverty, Surabhi Talele, Ashwin Bale, Brett L Carlson, Kendra A Porath, Katrina K Bakken, Danielle M Burgenske, Paul A Decker, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Rohit Bhargava, Zhenkun Lou, Petra Hamerlik, Brendan A C Harley, William F Elmquist, Zachary D Nagel, Shiv K Gupta, Jann N Sarkaria
Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization. Science translational medicine 16 (734) (2024)
Jiajia Chen, Daniel J Laverty, Surabhi Talele, Ashwin Bale, Brett L Carlson, Kendra A Porath, Katrina K Bakken, Danielle M Burgenske, Paul A Decker, Rachael Ann Vaubel, Jeanette E Eckel-Passow, Rohit Bhargava, Zhenkun Lou, Petra Hamerlik, Brendan A C Harley, William F Elmquist, Zachary D Nagel, Shiv K Gupta, Jann N Sarkaria
Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization. Science translational medicine 16 (734) (2024)
Daniel J Laverty, Shiv K Gupta, Gary A Bradshaw, Alexander S Hunter, Brett L Carlson, Nery Matias Calmo, Jiajia Chen, Shulan Tian, Jann N Sarkaria, Zachary D Nagel
ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma. Nature communications 15 (1) (2024)
Rumani Singh, Stacey J Yu, Marwa Osman, Zintis Inde, Cameron S Fraser, Abigail H Cleveland, Nicole Almanzar, Chuan Bian Lim, Gaurav N Joshi, Johan K E Spetz, Xingping Qin, Sneh M Toprani, Zachary D Nagel, Matthew C Hocking, Robert A Cormack, Torunn I Yock, Jeffrey W Miller, Zhi-Min Yuan, Timothy R Gershon, Kristopher A Sarosiek
Radiation therapy-induced neurocognitive impairment is driven by heightened apoptotic priming in early life and prevented by blocking BAX. Cancer research (2023)
Stefanie Koster, Rajendra Kumar Gurumurthy, Naveen Kumar, Pon Ganish Prakash, Jayabhuvaneshwari Dhanraj, Sofia Bayer, Hilmar Berger, Shilpa Mary Kurian, Marina Drabkina, Hans-Joachim Mollenkopf, Christian Goosmann, Volker Brinkmann, Zachary D Nagel, Mandy Mangler, Thomas F Meyer, Cindrilla Chumduri
Modelling Chlamydia and HPV co-infection in patient-derived ectocervix organoids reveals distinct cellular reprogramming. Nature communications 13 (1) (2022)
Cortt G Piett, T J Pecen, D J Laverty, Zachary D Nagel
Large-scale preparation of fluorescence multiplex host cell reactivation (FM-HCR) reporters. Nature protocols 16 (9) (2021)
Allyson E Koyen, Matthew Z Madden, Dongkyoo Park, Elizabeth V Minten, Priya Kapoor-Vazirani, Erica Werner, Neil T Pfister, Ramona Haji-Seyed-Javadi, Hui Zhang, Jie Xu, Nikita Deng, Duc M Duong, Turner J Pecen, Zoë Frazier, Zachary D Nagel, Jean-Bernard Lazaro, Kent W Mouw, Nicholas T Seyfried, Carlos S Moreno, Taofeek K Owonikoko, Xingming Deng, David S Yu
EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair. Oncogene 39 (25) (2020)
Zachary D Nagel, Andrew A Beharry, Patrizia Mazzucato, Gaspar J Kitange, Jann N Sarkaria, Eric T Kool, Leona D Samson
Fluorescent reporter assays provide direct, accurate, quantitative measurements of MGMT status in human cells. PloS one 14 (2) (2019)
Jerry H Houl, Zu Ye, Chris A Brosey, Lakshitha P F Balapiti-Modarage, Sarita Namjoshi, Albino Bacolla, Daniel Laverty, Brian L Walker, Yasin Pourfarjam, Leslie S Warden, Naga Babu Chinnam, Davide Moiani, Roderick A Stegeman, Mei-Kuang Chen, Mien-Chie Hung, Zachary D Nagel, Tom Ellenberger, In-Kwon Kim, Darin E Jones, Zamal Ahmed, John A Tainer
Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death. Nature communications 10 (1) (2019)
Mariangela Russo, Giovanni Crisafulli, Alberto Sogari, Nicole M Reilly, Sabrina Arena, Simona Lamba, Alice Bartolini, Vito Amodio, Alessandro Magrì, Luca Novara, Ivana Sarotto, Zachary D Nagel, Cortt G Piett, Alessio Amatu, Andrea Sartore-Bianchi, Salvatore Siena, Andrea Bertotti, Livio Trusolino, Mattia Corigliano, Marco Gherardi, Marco Cosentino Lagomarsino, Federica Di Nicolantonio, Alberto Bardelli
Adaptive mutability of colorectal cancers in response to targeted therapies. Science (New York, N.Y.) 366 (6472) (2019)