Mariana Laureano de Souza (Mariana Laureano De Souza, Mariana L de Souza, Mariana Laureano De Souza)

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 20

Top Topics

Molecular Dynamics Simulations

Trypanosoma Cruzi

Top Venues

Journal of medicinal chemistry

Nature communications

Future medicinal chemistry

Expert opinion on drug discovery

This page only lists publications with an associated author ORCID identifier.

Publications

Silvane Maria Fonseca Murta, Pedro Augusto Lemos Santana, Thibault Joseph William Jacques Dit Lapierre, André Berndt Penteado, Marissa El Hajje, Thabata Corazza Navarro Vinha, Daniel Barbosa Liarte, Mariana Laureano de Souza, Gustavo Henrique Goulart Trossini, Celso de Oliveira Rezende Júnior, Renata Barbosa de Oliveira, Rafaela Salgado Ferreira
New drug discovery strategies for the treatment of benznidazole-resistance in Trypanosoma cruzi , the causative agent of Chagas disease. Expert opinion on drug discovery 19 (6) (2024)
Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse A Dunn, Madeline R Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Kate J Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N Bhebhe, Dana M Klug, Peter J Rutledge, Luiz C Godoy, Sumanta Dey, Mariana Laureano de Souza, Jair L Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerald J Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas A Williamson, Gouranga P Jana, Bikash C Maity, Patrick Thomson, Thomas Foley, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus C S Lee, Elizabeth A Winzeler, Michael D W Griffin, Matthew H Todd, Leann Tilley
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature communications 15 (1) (2024)
Lushun Wang, Monica J Bohmer, Jinhua Wang, Flore Nardella, Jaeson Calla, Mariana Laureano de Souza, Kyra A Schindler, Lukas Montejo, Nimisha Mittal, Frances Rocamora, Mayland Treat, Jordan T Charlton, Patrick K Tumwebaze, Philip J Rosenthal, Roland A Cooper, Ratna Chakrabarti, Elizabeth A Winzeler, Debopam Chakrabarti, Nathanael S Gray
Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases. Journal of medicinal chemistry 67 (2) (2024)
Rocío Marisol Espinoza-Chávez, Celso de Oliveira Rezende Junior, Mariana Laureano de Souza, Ivani Pauli, Marilia Valli, Leonardo Luiz Gomes Ferreira, Rafael Consolin Chelucci, Simone Michelan-Duarte, Renata Krogh, Fernando Bezerra Romualdo da Silva, Fábio Cardoso Cruz, Aldo Sena de Oliveira, Adriano Defini Andricopulo, Luiz Carlos Dias
Structure-activity relationships of novel N -imidazoylpiperazines with potent anti- Trypanosoma cruzi activity. Future medicinal chemistry (2024)
Lushun Wang, Monica J Bohmer, Jinhua Wang, Flore Nardella, Jaeson Calla, Mariana Laureano de Souza, Kyra A Schindler, Lukas Montejo, Nimisha Mittal, Frances Rocamora, Mayland Treat, Jordan T Charlton, Patrick K Tumwebaze, Philip J Rosenthal, Roland A Cooper, Ratna Chakrabarti, Elizabeth A Winzeler, Debopam Chakrabarti, Nathanael S Gray
Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases. Journal of medicinal chemistry 67 (2) (2024)
Rocío Marisol Espinoza-Chávez, Celso de Oliveira Rezende Junior, Mariana Laureano de Souza, Ivani Pauli, Marilia Valli, Leonardo Luiz Gomes Ferreira, Rafael Consolin Chelucci, Simone Michelan-Duarte, Renata Krogh, Fernando Bezerra Romualdo da Silva, Fábio Cardoso Cruz, Aldo Sena de Oliveira, Adriano Defini Andricopulo, Luiz Carlos Dias
Structure-activity relationships of novel N -imidazoylpiperazines with potent anti- Trypanosoma cruzi activity. Future medicinal chemistry 16 (3) (2024)
Silvane Maria Fonseca Murta, Pedro Augusto Lemos Santana, Thibault Joseph William Jacques Dit Lapierre, André Berndt Penteado, Marissa El Hajje, Thabata Corazza Navarro Vinha, Daniel Barbosa Liarte, Mariana Laureano de Souza, Gustavo Henrique Goulart Trossini, Celso de Oliveira Rezende Júnior, Renata Barbosa de Oliveira, Rafaela Salgado Ferreira
New drug discovery strategies for the treatment of benznidazole-resistance in Trypanosoma cruzi , the causative agent of Chagas disease. Expert opinion on drug discovery 19 (6) (2024)
Silvane Maria Fonseca Murta, Pedro Augusto Lemos Santana, Thibault Joseph William Jacques Dit Lapierre, André Berndt Penteado, Marissa El Hajje, Thabata Corazza Navarro Vinha, Daniel Barbosa Liarte, Mariana Laureano de Souza, Gustavo Henrique Goulart Trossini, Celso de Oliveira Rezende Júnior, Renata Barbosa de Oliveira, Rafaela Salgado Ferreira
New drug discovery strategies for the treatment of benznidazole-resistance in Trypanosoma cruzi , the causative agent of Chagas disease. Expert opinion on drug discovery (2024)
Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse A Dunn, Madeline R Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Kate J Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N Bhebhe, Dana M Klug, Peter J Rutledge, Luiz C Godoy, Sumanta Dey, Mariana Laureano de Souza, Jair L Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerald J Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas A Williamson, Gouranga P Jana, Bikash C Maity, Patrick Thomson, Thomas Foley, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus C S Lee, Elizabeth A Winzeler, Michael D W Griffin, Matthew H Todd, Leann Tilley
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature communications 15 (1) (2024)
Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse A Dunn, Madeline R Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Kate J Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N Bhebhe, Dana M Klug, Peter J Rutledge, Luiz C Godoy, Sumanta Dey, Mariana Laureano de Souza, Jair L Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerald J Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas A Williamson, Gouranga P Jana, Bikash C Maity, Patrick Thomson, Thomas Foley, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus C S Lee, Elizabeth A Winzeler, Michael D W Griffin, Matthew H Todd, Leann Tilley
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature communications 15 (1) (2024)
Lushun Wang, Monica J Bohmer, Jinhua Wang, Flore Nardella, Jaeson Calla, Mariana Laureano de Souza, Kyra A Schindler, Lukas Montejo, Nimisha Mittal, Frances Rocamora, Mayland Treat, Jordan T Charlton, Patrick K Tumwebaze, Philip J Rosenthal, Roland A Cooper, Ratna Chakrabarti, Elizabeth A Winzeler, Debopam Chakrabarti, Nathanael S Gray
Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases. Journal of medicinal chemistry 67 (2) (2024)
Lushun Wang, Monica J Bohmer, Jinhua Wang, Flore Nardella, Jaeson Calla, Mariana Laureano de Souza, Kyra A Schindler, Lukas Montejo, Nimisha Mittal, Frances Rocamora, Mayland Treat, Jordan T Charlton, Patrick K Tumwebaze, Philip J Rosenthal, Roland A Cooper, Ratna Chakrabarti, Elizabeth A Winzeler, Debopam Chakrabarti, Nathanael S Gray
Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases. Journal of medicinal chemistry 67 (2) (2024)
Rocío Marisol Espinoza-Chávez, Celso de Oliveira Rezende Junior, Mariana Laureano de Souza, Ivani Pauli, Marilia Valli, Leonardo Luiz Gomes Ferreira, Rafael Consolin Chelucci, Simone Michelan-Duarte, Renata Krogh, Fernando Bezerra Romualdo da Silva, Fábio Cardoso Cruz, Aldo Sena de Oliveira, Adriano Defini Andricopulo, Luiz Carlos Dias
Structure-activity relationships of novel N -imidazoylpiperazines with potent anti- Trypanosoma cruzi activity. Future medicinal chemistry 16 (3) (2024)
Rocío Marisol Espinoza-Chávez, Celso de Oliveira Rezende Junior, Mariana Laureano de Souza, Ivani Pauli, Marilia Valli, Leonardo Luiz Gomes Ferreira, Rafael Consolin Chelucci, Simone Michelan-Duarte, Renata Krogh, Fernando Bezerra Romualdo da Silva, Fábio Cardoso Cruz, Aldo Sena de Oliveira, Adriano Defini Andricopulo, Luiz Carlos Dias
Structure-activity relationships of novel N -imidazoylpiperazines with potent anti- Trypanosoma cruzi activity. Future medicinal chemistry 16 (3) (2024)
Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse A Dunn, Madeline R Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Kate J Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N Bhebhe, Dana M Klug, Peter J Rutledge, Luiz C Godoy, Sumanta Dey, Mariana Laureano de Souza, Jair L Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerald J Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas A Williamson, Gouranga P Jana, Bikash C Maity, Patrick Thomson, Thomas Foley, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus C S Lee, Elizabeth A Winzeler, Michael D W Griffin, Matthew H Todd, Leann Tilley
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature communications 15 (1) (2024)
Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Charisse Flerida A Pasaje, Elyse A Dunn, Madeline R Luth, Krittikorn Kumpornsin, Eva S Istvan, Joon Sung Park, Kate J Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N Bhebhe, Dana M Klug, Peter J Rutledge, Luiz C Godoy, Sumanta Dey, Mariana Laureano de Souza, Jair L Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerald J Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas A Williamson, Gouranga P Jana, Bikash C Maity, Patrick Thomson, Thomas Foley, Derek S Tan, Jacquin C Niles, Byung Woo Han, Daniel E Goldberg, Jeremy N Burrows, David A Fidock, Marcus C S Lee, Elizabeth A Winzeler, Michael D W Griffin, Matthew H Todd, Leann Tilley
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nature communications 15 (1) (2024)
Lushun Wang, Monica J Bohmer, Jinhua Wang, Flore Nardella, Jaeson Calla, Mariana Laureano de Souza, Kyra A Schindler, Lukas Montejo, Nimisha Mittal, Frances Rocamora, Mayland Treat, Jordan T Charlton, Patrick K Tumwebaze, Philip J Rosenthal, Roland A Cooper, Ratna Chakrabarti, Elizabeth A Winzeler, Debopam Chakrabarti, Nathanael S Gray
Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases. Journal of medicinal chemistry (2024)
Mariana Laureano de Souza, Thibault Joseph William Jacques Dit Lapierre, Gabriel Vitor de Lima Marques, Witor Ribeiro Ferraz, André Berndt Penteado, Gustavo Henrique Goulart Trossini, Silvane Maria Fonseca Murta, Renata Barbosa de Oliveira, Celso de Oliveira Rezende, Rafaela Salgado Ferreira
Molecular targets for Chagas disease: validation, challenges and lead compounds for widely exploited targets. Expert opinion on therapeutic targets (2023)
Tyler Eck, Mariana Laureano de Souza, Melvin Delvillar, Kutub Ashraf, Rammohan R Yadav Bheemanaboina, Ramappa Chakrasali, Tamara Kreiss, John J Siekierka, David P Rotella, Purnima Bhanot, Nina M Goodey
Characterization of Competitive Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase. Chembiochem : a European journal of chemical biology 23 (7) (2022)
Alex R Medeiros, Leonardo Luiz Gomes Ferreira, Mariana Laureano de Souza, Celso de Oliveira Rezende Junior, Rocío Marisol Espinoza-Chávez, Luiz Carlos Dias, Adriano Defini Andricopulo
Chemoinformatics Studies on a Series of Imidazoles as Cruzain Inhibitors. Biomolecules 11 (4) (2021)